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Search Results: 1 - 10 of 12806 matches for " Marcelo;Velasques "
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é necessária a realiza??o de biópsia de medula óssea bilateral para o estadiamento do linfoma difuso de grandes células B?
Bellesso, Marcelo;Velasques, Rodrigo Dolphini;Pracchia, Luis Fernando;Beitler, Beatriz;Aldred, Vera Lúcia;Chamone, Dalton Alencar Fisher;Pereira, Juliana;
Jornal Brasileiro de Patologia e Medicina Laboratorial , 2009, DOI: 10.1590/S1676-24442009000200004
Abstract: this retrospective study aims to analyze the usefulness of bilateral bone marrow biopsy in bone marrow infiltration by diffuse large b-cell lymphoma (dlbcl). our objectives were to assess the incidence of unilateral bm involvement by dlbcl and compare fragment length obtained from positive and negative samples for infiltration. furthermore, we compared the differences between unilateral and bilateral infiltration correlating with lactic dehydrogenase (ldh) and computerized tomography (ct) staging. we evaluated 268 cases of dlbcl and observed medullary infiltration in 34 cases (13%). it was not possible to evaluate 6 out of 34 cases. 70 bm fragments were reviewed as to the presence or absence of infiltration and length. the mean number of fragments per case was 2.5; the mean bm fragment length was 11.01 mm (± 5.12 mm) and the mean bm fragment length per case was 27.53 mm. there was unilateral bm infiltration in six cases (21.4%). there were no differences in the mean fragment length as to the presence/absence of infiltration 10.95 mm (± 5.2 mm) versus 11.57 mm, p > 0.05, respectively. there were no differences in 23 cases between the comparison of unilateral medullary infiltration versus bilateral with lactic dehydrogenase and ct staging. we concluded that bilateral bone marrow biopsy was superior to unilateral because it may increase by 21.4% the detection of bm involvement by dlbcl.
Investigation of the occurrence of Mansonella ozzardi in the State of Rond?nia, Western Amazonia, Brazil
Basano, Sergio de Almeida;Camargo, Juliana de Souza Almeida Aranha;Vera, Luana Janaína de Souza;Velasques, Suzane Neves;Ogawa, Guilherme Maerschner;Medeiros, Jansen Fernandes;Fontes, Gilberto;Camargo, Luís Marcelo Aranha;
Revista da Sociedade Brasileira de Medicina Tropical , 2011, DOI: 10.1590/S0037-86822011005000055
Abstract: introduction: mansonella ozzardi, a human filarial nematode transmitted by diptera simuliidae flies (black flies), is widely spread in the amazon, while the occurrence of mansonelliasis in the state of rond?nia (western amazonia) has not been reported thus far. the existence of this parasitic disease in this state is investigated in this study. methods: a total of 4,452 people who lived alongside the madeira, mamore, guapore, machado and preto rivers, in the state of rond?nia, were examined using the thick blood smear method. alongside the machado and guapore rivers, 2,112 adult simuliid specimens were captured. results: infected people were not reported, although simuliids with vector potential such as cerqueirellum pydanielli, c. argentiscutum and c. amazonicum were found. conclusions: this study registered no infected people. this finding may be explained by the individuals' low level of microfilaremia that is below the limit of detection of the diagnostic method used in the study or insufficient migration of people infected with m. ozzardi from endemic areas, making it impossible to introduce the disease into rond?nia. further studies using more sensitive diagnostic techniques could shed light on this question.
Neurorestorative Effects of Constraint-Induced Movement Therapy after Stroke: An Integrative Review  [PDF]
Marina Lucas, Pedro Ribeiro, Mauricio Cagy, Silmar Teixeira, Fernanda Chaves, Diana Carvalho, Caroline Peressutti, Sérgio Machado, Juliana Bittencourt, Bruna Velasques, Roberto Piedade
Neuroscience & Medicine (NM) , 2013, DOI: 10.4236/nm.2013.44036

Stroke has been considered as one of the main causes of death and of motor and cognitive sequels. Especially, many patients with upper limb hemiparesis improved their motor action and showed meaningful cortical changes after treatment with constraint-induced movement therapy. Therefore, this review aims to verify the literature about neuroimaging and behavioral evidences in the cortical reorganization through the use of the constraint-induced movement therapy. So, we conducted the literature research in indexed journals from many databases like Pubmed, Medline, Cochrane Database, Lilacs and Scielo. We concluded that the behavioral and neuroimaging studies using traditional and modified constraint-induced movement therapy promote cortical reorganization.

Activities, procedures and doses in pediatric patients due to radiopharmaceuticals
Oliveira, Silvia Maria Velasques de;Boasquevisque, Edson Mendes;Santos, Felipe Sima dos;Biancardi, Rodrigo;
Brazilian Archives of Biology and Technology , 2008, DOI: 10.1590/S1516-89132008000700019
Abstract: an investigation performed between 2003 and 2005 in sixteen selected public and private institutions in northeast, southeast and south geographical regions of brazil evaluated average organ doses and effective doses in 2,411 pediatric patients due to diagnostic procedures with radiopharmaceuticals. for 1 year, effective doses were greater than literature. for 5 years, differences were noticed between present work and literature for bone scintigraphy, thyroid scintigraphy and 67ga citrate scintigraphy. these differences may be attributed to the uncertainties in internal dose calculations. high absorved doses in bone surfaces of children due to 67ga citrate and bone scintigraphy should be evaluated accordingly. current protocols used recommend standardized mean activities per mean weight for all ages. however, it was observed that the activities were not standardized and were higher for children with younger ages. future studies are needed for optimising activities of radiopharmaceuticals to these patients in the country.
Motor learning processes: an electrophysiologic perspective
Velasques, Bruna;Ferreira, Camila;Teixeira, Silmar Silva;Furtado, Vernon;Mendes, Elizabeth;Basile, Luis;Cagy, Mauricio;Piedade, Roberto;Ribeiro, Pedro;
Arquivos de Neuro-Psiquiatria , 2007, DOI: 10.1590/S0004-282X2007000600005
Abstract: the goal of the present study was to investigate electrophysiologic, qeeg, changes when individuals were exposed to a motor task. subjects? brain electrical activity was analyzed before and after the typewriting training task. for the neurophysiological variable asymmetry, a paired t-test was performed to compare each moment, pre and post-task, in the beta bands. the findings showed a change for the qeeg variable in each scalp site, f3/f4; c3/c4 and p3/p4. these results suggest an adaptation of pre-frontal, sensory-motor and parietal cortex, as a consequence of the typewriting training.
Clinical Psychophysical Assessment of the ON- and OFF-Systems of the Magnocellular and Parvocellular Visual Pathways  [PDF]
Marcelo Fernandes Costa
Neuroscience & Medicine (NM) , 2011, DOI: 10.4236/nm.2011.24043
Abstract: We developed a psychophysical paradigm for the clinical assessment of the contrast sensitivity (CS) mediated by the ON- and OFF-systems of the Magnocellular and Parvocellular pathways. We designed a stimulus considering two dimensions: two spatial frequencies (0.5 and 4.5 cpd) and two temporal rates of flicker (33 ms and 1500 ms). To evidence the ON- and OFF responses, the CS was measured for two polarities of light with luminance changes of 0.6 dB steps above and below the medium luminance grey background. We tested 38 healthy volunteers. The results shows that Magnocellular contrast sensitivity was higher than Parvocellular for the 33 ms flickering stimulus and the Parvocellular contrast sensitivity was higher than Magnocellular for 1500 ms stimuli. The reliability of the test was checked and confirmed. We concluded that the test performs a rapid measurement of the CS mediated by the ON and OFF systems of Magnocellular and Parvocellular pathways. It is useful in clinical protocols due to its high sensitivity and good reliability.
Heat Flow as Origin of Dark Energy  [PDF]
Marcelo Samuel Berman
Journal of Modern Physics (JMP) , 2013, DOI: 10.4236/jmp.2013.410175

We first introduce entropy according to University Physics textbooks, then, briefly discuss it, and then we prove by a general relativistic derivation that the Universe has entropy growth, like a white-hole, that it is R2-dependent, and that dark energy, represented by a cosmological constant, is caused by heat flow, and provides for entropy growth.

Cortical asymmetry: catching an object in free fall
Velasques, Bruna;Machado, Sergio;Portella, Cláudio Elidio;Silva, Julio Guilherme;Terra, Patrícia;Ferreira, Camila;Basile, Luis;Cagy, Mauricio;Piedade, Roberto;Ribeiro, Pedro;
Arquivos de Neuro-Psiquiatria , 2007, DOI: 10.1590/S0004-282X2007000400015
Abstract: the main goal of the present study was to analyze theta asymmetry through quantitative electroencephalography (qeeg) when individuals were exposed to a sequential motor task, i.e. catching a ball. the sample was composed of 23 healthy subjects, male and female, between 25 and 40 years of age. a two-way factor anova was applied to compare pre and post moments related to the balls' drop and scalp regions (i.e., frontal and parieto-occipital cortices). the first analysis of the frontal region compared electrodes in the left, right and left/right hemispheres combined, with the frontal midline electrode (fz) included in the analysis. the results showed moment and region main effects. the second analysis compared left versus right hemisphere without the fz site. the findings demonstrated an interaction effect between moment and region. the first parieto-occipital analysis, comparing left, right and central regions, with pz included in all regions, showed main effects of moment and region. the second analysis, comparing left, right (without pz) and central regions strictly demonstrated a region main effect. thus, we observed an asymmetric pattern in the frontal cortex (i.e., planning and response selection) when the subjects were waiting for the balls' drop. moreover, the left hemisphere seems to engage differently from the other regions when the central nervous system needs to prepare for a motor action. on the other hand, the parieto-occipital cortex, which is related to attentive processes, demonstrated a more asymmetric activity towards the right region which implies a participation of this area in cognitive strategies in this particular task. taken together, we concluded that the adopted experimental approach can be useful to explore several others directions combining sensorimotor integration tasks with different pathologies, such as depression, alzheimer's and parkinson's diseases.
Effects of a cognitive modulator in the theta and alpha asymmetry during a typewriting task: a sensorimotor integration perspective
Cunha, Marlo;Machado, Sergio;Miana, Luiz Cláudio;Machado, Dionis;Bastos, Victor Hugo;Velasques, Bruna;Cagy, Maurício;Basile, Luis F.;Piedade, Roberto;Ribeiro, Pedro;
Arquivos de Neuro-Psiquiatria , 2009, DOI: 10.1590/S0004-282X2009000200008
Abstract: this study aimed to elucidate cortical mechanisms and to identify the areas where occur such mechanisms due to interaction between bromazepam and motor learning. the sample was composed of 45 healthy subjects randomly distributed in 3 groups: placebo (n=15), bromazepam 3 mg (n=15) or bromazepam 6 mg (n=15). to perform the experimental task, subjects sat comfortably at a distance of approximately 20 cm from the typewriter. the typewriter keyboard was covered with a wooden box to avoid visual information about the hands' position. the typewriting task was performed concomitantly with eeg recording. anova two-way results indicated a decreased asymmetry in sensorimotor areas in the experimental groups. our interpretation is that moderate doses of bromazepam may improve performance on tasks with predictable elements to promote stability of psychomotor functions, but may also impair performance on tasks executed in unpredictable environments.
Alzheimer's disease and implicit memory
Machado, Sergio;Cunha, Marlo;Minc, Daniel;Portella, Claudio Elidio;Velasques, Bruna;Basile, Luis F.;Cagy, Maurício;Piedade, Roberto;Ribeiro, Pedro;
Arquivos de Neuro-Psiquiatria , 2009, DOI: 10.1590/S0004-282X2009000200034
Abstract: specific neuropsychiatric disorders, such as alzheimer's disease (ad) affect some forms of memory while leaving others relatively intact. in this review, we investigate particularities of the relationship between explicit and implicit memories in ad. it was found that implicit memory is preserved in ad, irrespective of the task used; in other words, there was not interference from explicit memory. in addition, it was verified that is possible through implicit memory compensatory strategies such as, activities of daily living (adl) to compensate for the explicit memory deficits. in this sense, cognitive rehabilitation (cr) demonstrates reasonable results in the process of compensation of explicit memory deficits. concluding, the decline in explicit memory suggests that both systems are functionally independent even if the other is compromised. we expect that when explicit memory system is not involved in competition with the implicit system, the final effect of learning is better, because all of the implicit memory capacity is engaged in learning and not in competition with the explicit system.
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