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Search Results: 1 - 10 of 12788 matches for " Marcelo;Serralheiro "
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Efeito do priming na redu??o da latência do pipecur?nio, novo bloqueador neuromuscular n?o-despolarizante
Canga, José Carlos;Lehn, Carlos Neutzling;Tonelli, Deoclécio;Sacco, Paula de Camargo Neves;Beltr?o, Danielle;Kirsch, Marcelo;Serralheiro, Fernando César;Cimerman, Gustavo;
Revista Brasileira de Anestesiologia , 2005, DOI: 10.1590/S0034-70942005000400002
Abstract: background and objectives: one of the most important neuromuscular blockers property is short onset, allowing early tracheal intubation. low nondepolarizing blocker dose before the full dose is known to decrease the onset of most neuromuscular blockers. pipecuronium bromide is a long-lasting aminosteroid with major cardiovascular stability, however, with late onset. this study aimed at evaluating pipecuronium priming effect in adult patients submitted to elective surgeries under general anesthesia. methods: participated in this study 33 adult patients of both genders, aged 20 to 65 years, physical status asa i or ii, to be submitted to elective surgeries under general anesthesia. exclusion criteria were patients with kidney or liver failure, neuromuscular diseases, in concurrent use of drugs influencing pipecuronium pharmacokinetics, and patients with family history of malignant hyperthermia. patients were divided in 2 groups: group 1 = priming with 0.01 mg.kg-1 and 3 minutes later the remaining 0.07 mg.kg-1 (total 0.08 mg.kg-1); group 2 = no priming dose (group control). neuromuscular relaxation was controlled by acceleromyography (tof-guard device) and laryngoscopy was accomplished when t1 < 10%. t test for independent samples was used for statistical analysis and shapiro wilks was used to test normality. results: groups were homogeneous. time for t1 < 10% was 161.4 ± 13.7 seconds for group 1 and 217.8 ± 23.4 seconds for group 2, with p < 0.001 and statistically significant differences between groups. conclusions: our results have shown statistically significant differences between groups with and without priming, indicating that pipecuronium also has its onset decreased, similarly to other known neuromuscular blockers.
Influência do comprimento do sulco sobre a equa??o de infil-tra??o obtida pelo método dos dois pontos de Elliot & Walker
Shahidian,S.; Serralheiro,R.P.; Serrano,J.;
Revista de Ciências Agrárias , 2010,
Abstract: the kostiakov infiltration equation can be established by the two point method of el-liot and walker. nevertheless, there are no indications as to how the two points should be selected. in this paper different pairs of points along a 220m long furrow are used to calculate the corresponding infiltration equation. the results indicate that the expo-nent of the equation increases with the length of the furrow, and with distance to the first point. the k of the equation behaves in the opposite direction, decreasing with an increase in the length of the furrow. it is recommended that the first measurement point should be located half way between the furrow inlet and the second measure-ment point.
Resposta das culturas do girassol e do milho a diferentes cenários de rega deficitária
Toureiro,C. M.; Serralheiro,R. P.; Oliveira,M. R.;
Revista de Ciências Agrárias , 2007,
Abstract: some results are presented from a project aiming the water use optimisation from an environmental point of view. this means that the decision criterion in irrigation management is ?deficit irrigation?, rather than maximum etc as the irrigation water amount. some experiments with ?deficit irrigation? of a sunflower crop (in 2004 irrigation season) and maize (in 2005) were carried out in the irrigation district of divor (alentejo, south portugal). crop growth and production parameters were evaluated relative to three experimental irrigation regimes: 1) irrigation opportunity and amount with soil available water equalling ?optimum yield level?, this corresponding to a non restrictive water use by the crop, according to current procedure, irrigation amount corresponding to maximum etc; 2) and 3) levels 1 and 2 of deficit irrigation, considering irrigation opportunity with soil available water respectively 10% and 30% under the ?optimum yield level? and irrigation amounts 10% and 30% less than etc between irrigation events. during the flowering periods normal irrigation for full etc was practiced in all experiment plots. crop yield data and the economic analysis show that a remarkable potential exists for saving water with ?deficit irrigation?.
Resposta das culturas do girassol e do milho a diferentes cenários de rega deficitária Deficit irrigation as a criterion for irrigation water management with sunflower and maize crops
C. M. Toureiro,R. P. Serralheiro,M. R. Oliveira
Revista de Ciências Agrárias , 2007,
Abstract: Apresentam-se alguns resultados de um projecto em que se procura integrar, nos critérios de decis o sobre a oportunidade e a dota o de rega, a optimiza o da produtividade ambiental da água, valorizando-se maximamente a utiliza o desse recurso escasso. Surge assim a defini o de critérios de gest o da rega em que as dota es s o “deficitárias”, isto é, em que se fornece à cultura uma quantidade de água inferior à correspondente à ETc calculada. Durante as campanhas de rega de 2004 e 2005 decorreram ensaios experimentais com “rega deficitária”, em parcelas regadas do Perímetro do Divor: em 2004 avaliou-se e caracterizou-se o comportamento da cultura do girassol, sujeita a diferentes regimes hídricos, com três cenários diferentes de decis o para definir a oportunidade e dota o de rega: 1) considerando como oportunidade de rega (ponto de rega) o limite inferior de gest o (ou défice de gest o permissível), tradicionalmente definido por limite do rendimento óptimo (LRO) na zona da reserva facilmente utilizável do solo; 2) e 3) considerando como oportunidade de rega (ponto de rega) dois limites abaixo do LRO (10 e 30%, respectivamente); em 2005 avaliou-se e caracterizou-se o comportamento da cultura do milho, sujeita a três cenários de gest o da água de rega: 1) regime óptimo de fornecimento de água igual às necessidades hídricas da cultura, traduzidas pela ETc calculada; 2) nível 1 de “rega deficitária” regime de regas 10% abaixo do valor de ETc; 3) nível 2 de “rega deficitária” regime de regas 30% abaixo do valor de ETc. Durante as fases de desenvolvimento da cultura mais sensíveis ao défice de água no solo, as três modalidades de ensaio foram regadas de igual modo (nível de fornecimento de água igual ao valor de ETc. Verificou-se um nítido potencial de economia de água proporcionável pela gest o da cultura com “rega deficitária”. Some results are presented from a project aiming the water use optimisation from an environmental point of view. This means that the decision criterion in irrigation management is “deficit irrigation”, rather than maximum ETc as the irrigation water amount. Some experiments with “deficit irrigation” of a sunflower crop (in 2004 irrigation season) and maize (in 2005) were carried out in the Irrigation District of Divor (Alentejo, South Portugal). Crop growth and production parameters were evaluated relative to three experimental irrigation regimes: 1) irrigation opportunity and amount with soil available water equalling “optimum yield level”, this corresponding to a non restrictive water use by the crop, according to current pro
Influência do comprimento do sulco sobre a equa o de infil-tra o obtida pelo método dos dois pontos de Elliot & Walker Influence of furrow length on the infiltration equation obtained by the two point method of Elliot & Walker
S. Shahidian,R.P. Serralheiro,J. Serrano
Revista de Ciências Agrárias , 2010,
Abstract: A Equa o de infiltra o do tipo Kostiakov pode ser determinada através do método dos dois pontos de Elliot & Walker. No entanto n o existem normas para a selec o dos dois pontos. No presente trabalho foram utilizados diferentes pares de pontos ao longo de um sulco com 220m para calcular as correspon-dentes equa es de infiltra o. Os resultados demonstram que o expoente a da equa o aumenta com o comprimento de sulco consi-derado, e com a distancia até ao ponto do meio. Por sua vez, o coeficiente k tem um comportamento inverso, diminuindo com o aumento do comprimento do sulco. Assim, e por forma a que haja uma uniformidade de critérios, é recomendável que o primeiro pon-to esteja o mais próximo da meia distancia entre a cabeceira e o segundo ponto. The Kostiakov infiltration equation can be established by the two point method of El-liot and Walker. Nevertheless, there are no indications as to how the two points should be selected. In this paper different pairs of points along a 220m long furrow are used to calculate the corresponding infiltration equation. The results indicate that the expo-nent of the equation increases with the length of the furrow, and with distance to the first point. The k of the equation behaves in the opposite direction, decreasing with an increase in the length of the furrow. It is recommended that the first measurement point should be located half way between the furrow inlet and the second measure-ment point.
Interaction between Plectranthus barbatus herbal tea components and human serum albumin and lysozyme: Binding and activity studies
Pedro L. V. Falé,Lia Ascens o,Maria L. M. Serralheiro,Parvez I. Haris
Spectroscopy: An International Journal , 2011, DOI: 10.3233/spe-2011-0532
Abstract: Anti-cholinesterase and antioxidant active constituents of Plectranthus barbatus aqueous extract were found in plasma of rats after its administration – rosmarinic acid, luteolin and apigenin. The aim of the present work is to determine if the extract components can interact with human plasma proteins, namely albumin and lysozyme. Protein intrinsic fluorescence analysis showed that the plant phenolic compounds may bind to albumin, the main transport protein in plasma, and to lysozyme. The estimated thermodynamic parameters suggest that the main intermolecular interaction is hydrophobic association. FTIR analysis of the protein amide bands showed that the plant extract components do not alter the secondary structure of either albumin or lysozyme, however the rate of hydrogen–deuterium exchange suggests that tertiary structure changes might have occurred. An increase of hydrogen deuterium exchange suggests that rosmarinic acid may bind to the fatty acid binding sites in albumin, while luteolin and apigenin may bind to the drug binding sites. The plant extract components also inhibit lysozyme activity with IC50 values around 100 μM. Therefore P. barbatus herbal tea, rosmarinic acid, luteolin and apigenin interact and may be transported by albumin and lysozyme. The inhibition of lysozyme activity may be an additional mechanism for its anti-inflammatory activity.
Caracteriza??o do enraizamento da beterraba sacarina (Beta vulgaris L.) num solo de aluvi?o
Toureiro,C. M.; Brasi,F. C.; Oliveira,M. R.; Serralheiro,R. P.;
Revista de Ciências Agrárias , 2007,
Abstract: knowledge of plant rooting patterns and their evolution during the crop season is important for the apropriate soil water and nutrients management. the implementation of efficient irrigation practices ? such as the irrigation management in real time for a certain area ? needs information on meteorological, soil and crop parameters: such as crop growth stage, crop coefficients, paths of rooting depth, crop sensitivity to water stress, allowable soil water deficit, etc. also, the characteristics of irrigation events should also be known, normally irrigation amount, opportunity, and evaluation. the objective of the present study is to evaluate a sugar beet crop growth including root growth pattern, on an alluvial soil, under irrigation to give the crop the optimum water amount for maximum growth. the minirizotron method was used for monitoring root growth during crop season. later on, trenches were opened for directly observing and measuring root development and pattern, up to 50 cm depth. beet root depth and weight were evaluated at several points ? growing stage from 0 to 69 days after seeding (das), yield formation from 69 to 166 das, and ripening from 166 to 196 das - and crop growth indices were also determined: leaf area index (lai), and the duration of crop growing stages. finally, biomass and grain production were evaluated. data obtained showed that: 1) maximum values for biomass and lai were observed at 96 to 111 days, the values decreasing afterwards, while leaf senescence and rapid root growth occurred; and 2) mass and depth of the beet root was observed to increase throughout the crop cicle, but faster between 96 and 111 das, reaching 2000 g and 40 cm respectively at 196 das. images obtained with the minirizotron showed that fine beet roots had grown down to 90 cm depth.
Sex inversion of dusky grouper “Epinephelus marginatus” Invers o sexual da garoupa-verdadeira "Epinephelus marginatus"
Eduardo Gomes Sanches,Idili da Rocha Oliveira,Pedro Carlos da Silva Serralheiro
Revista Brasileira de Saúde e Produ??o Animal , 2009,
Abstract: This study aimed to evaluate the induced hormonal sex inversion of females using the androgenic 17 alpha-methyltestosterone supplied orally and injectable. Twenty-seven fish with 863.9 ± 231.2 g were divided into three treatments: T1 = control (groupers that did not receive hormone), T2 = orally treatment (groupers fed pieces of fish by which the hormone was administered) and T3 = injectable treatment (groupers that received the hormone by intramuscular injection) and maintained in floating net cages, in Ubatuba, State of S o Paulo, Brazil. In the orally treatment the androgenic dosage was 1 mg/kg of body weight, daily, for 5 days a week, and in the injectable treatment, the dosage was 5 mg/kg of body weight, weekly, in a single dose. After 180 days, 100 and 77.8% of fish of the orally and injectable treatments, respectively, produced semen and the control group remained as females. The most effective sex inversion of Epinephelus marginatus females was achieved by the use of hormone 17 alpha-methyltestosterone in the dosage of 1 mg/kg of body weight, administered orally with the food. The hormone 17 alpha-methyltestosterone produces an anabolyzant parallel effect and increase weight gain of the fish treated with oral application. Neste estudo pretendeu-se avaliar a invers o sexual de fêmeas por meio de indu o hormonal, utilizando-se o andrógeno 17 alfa-metiltestosterona, ministrado via oral e injetável. Vinte e sete peixes com 863,9 ± 231,2 g foram divididos em três tratamentos: T1 = controle (garoupas que n o receberam horm nio), T2 = tratamento via oral (garoupas alimentadas com peda os de peixe através do qual foi administrado o horm nio) e T3 = tratamento via injetável (garoupas que receberam o horm nio por inje o intramuscular) e mantidos em tanques-rede no mar, em Ubatuba/SP. No tratamento via oral, a dosagem de andrógeno foi de 1 mg/kg de peso corporal, diariamente, durante 5 dias por semana, e no tratamento via injetável, de 5 mg/kg de peso corporal, semanalmente, em uma única dose. Após 180 dias, 100 e 77,8%, respectivamente, dos peixes do tratamento via oral e via injetável produziram sêmen, ao passo que os do tratamento controle mantiveram-se como fêmeas funcionais. A invers o sexual induzida de fêmeas de Epinephelus marginatus mais efetiva foi a realizada com o uso do horm nio 17-alfa-metiltestosterona, na dosagem de 1 mg/kg de peso corporal, administrada via oral junto com o alimento. O horm nio 17-alfa-metiltestosterona proporciona efeito anabolizante paralelo e incrementa o ganho de peso dos exemplares que recebem aplica o oral.
Rearing of fat snook (“Centropomus parallelus”) at different stocking densities Cria o do robalo-peva ("Centropomus parallelus") submetido a diferentes densidades de estocagem
Sergio Ostini,Idili da Rocha Oliveira,Pedro Carlos da Silva Serralheiro,Eduardo Gomes Sanches
Revista Brasileira de Saúde e Produ??o Animal , 2007,
Abstract: Studies on the effect of stocking density on the growth of fat snook Centropomus parallelus were conducted in floating net cages in the north coast of the State of S o Paulo, in Ubatuba City. Juveniles weighing 32.53 ± 6.54 g were stocked in densities of 20 and 40 fish/m3 and appraised for 160 days. Fish were fed commercial diet with 40% of crude protein, supplied twice a day, at the rate of 3% biomass of each tank-net. The environmental variables (water temperature, oxygen level, salinity and transparency) were according to the parameters considered ideals for the species. Survival and the apparent feed conversion were not different (p <0.05) between the treatments. The mean final weights, specific growth rate and daily gain weight, indicated that the treatment of lower density was (p <0.05) superior to higher density. In relation to total weight gain, an accretion was observed of 98.6 and 87.9 g for the densities of 20 and 40 fishes/ m3, respectively. However, final biomass was superior (p<0.05) for the treatment with higher density, demonstrating a straight relationship between density and biomass production observed in the fish farming. Estudos sobre o efeito da densidade de estocagem na sobrevivência e no desempenho produtivo do robalo-peva Centropomus parallelus, criado em tanque-rede, foram realizados no litoral norte do Estado de S o Paulo, em Ubatuba. Juvenis pesando 32,53 ± 6,54 g foram estocados em densidades de 20 e 40 peixes/m3 e avaliados durante 160 dias. Os peixes foram alimentados com ra o comercial com 40% de proteína bruta, fornecida duas vezes ao dia, à taxa de 3% da biomassa de cada tanque-rede.. As variáveis ambientais (temperatura da água, teor de oxigênio, salinidade e transparência) mantiveram-se dentro dos parametros considerados ideais para a espécie. Em rela o à sobrevivência e a convers o alimentar aparente, n o foram observadas diferen as significativas (p<0.05) entre os tratamentos. As médias de pesos finais, taxa de crescimento específico e ganho de peso diário, indicaram que o tratamento de menor densidade foi significativamente (p< 0,05) superior ao de maior densidade. Em rela o ao ganho de peso total, observou-se um incremento na ordem de 98,6 e 87,9 g para as densidades de 20 e 40 animais / m3, respectivamente. Entretanto, a biomassa final foi significativamente (p<0,05) superior no tratamento com maior densidade, demonstrando a rela o direta existente entre densidade e produ o de biomassa comumente observada na piscicultura.
Caracteriza o do enraizamento da beterraba sacarina (Beta vulgaris L.) num solo de aluvi o Rooting pattern of sugar beet (Beta vulgaris L. var. saccharifera) in a soil from alluvium
C. M. Toureiro,F. C. Brasi,M. R. Oliveira,R. P. Serralheiro
Revista de Ciências Agrárias , 2007,
Abstract: O conhecimento do padr o de enraizamento das culturas e sua evolu o ao longo do ciclo cultural é importante para a gest o do uso da água e nutrientes do solo. A promo o de práticas de rega eficientes – como a condu o da água de rega em tempo real numa determinada área – requer o conhecimento, para além de parametros meteorológicos e pedológicos, de parametros culturais, como dura o dos estádios de desenvolvimento da cultura, coeficientes culturais, capacidade de aprofundamento radical, sensibilidade da cultura à deficiência hídrica, défice de gest o permissível e dos parametros que caracterizam as regas efectuadas durante a campanha (data e dota o de rega efectivamente aplicada e avalia o dos sistemas de rega utilizados). O presente estudo teve como objectivo avaliar o desenvolvimento da cultura da beterraba, num solo de aluvi o (A – Solos Incipientes, Aluviossolo Moderno n o Calcário de Textura Mediana), do Perímetro de Rega do Divor, cujo cenário de gest o da água de rega utilizado foi a optimiza o do rendimento óptimo da cultura. No ensaio realizado com a cultura da beterraba, durante a campanha de rega de 2004 (Primavera-Ver o), utilizou-se o método do minirizotr o, com o qual é possível acompanhar as varia es temporais e espaciais do desenvolvimento radical da cultura, permitindo uma caracteriza o do sistema radical como órg o dinamico. Para além deste método procedeu-se à abertura de perfis, perpendicularmente à linha de cultura, até à profundidade de 50 cm. Em várias datas de observa o durante o ciclo cultural, avaliou-se a capacidade de aprofundamento e peso do túberculo. Em complemento, avaliaram-se outros índices culturais tais como a dura o dos estados fenológicos, o índice de área foliar (IAF), matéria verde da parte aérea e a produ o total. Consideraram-se as seguintes épocas de observa o: desenvolvimento vegetativo (0-69 dias após a sementeira (DAS); desenvolvimento vegetativo e forma o do túberculo (69-166 DAS) e matura o (166-196 DAS). Os resultados obtidos mostram o seguinte: 1) Relativamente aos parametros da parte aérea da cultura: os valores máximos relativos à massa verde e índice de área foliar ocorreram no período de 96-111 DAS, após o qual se registou um decréscimo acentuado dos valores, coincidindo com o início da senescência da parte aérea da cultura e o desenvolvimento rápido do tubérculo; e 2) Relativamente aos parametros radicais e tubérculo: a evolu o da massa e da profundidade da localiza o do tubérculo foi crescente ao longo do ciclo, mais significativa a partir dos 96-111 DAS, atingindo os valores máximos
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