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200 a os de Libertad, y una historia de sue os cumplidos
Bencomo, María Ninón
Salud, Arte y Cuidado , 2011,
Abstract: Con inmenso júbilo en el marco de la conmemoración del bicentenario, nueve países de nuestra América: Argentina, Bolivia, Chile, Colombia, Ecuador, México, Paraguay, Uruguay y Venezuela, celebramos el Bicentenario de la Independencia. Los festejos que se iniciaron en el 2009 y culminarán este a o 2011, deben asumirse como un momento para reflexionar sobre el futuro de la región. Hace doscientos a os América pensó que debía luchar para dar paso a una nueva visión del mundo, era ya inadmisible las terribles condiciones de disconformidades económicas y sociales donde los pueblos estaban oprimidos gracias a la Corona Espa ola, por ello se originaron movimientos independentistas que anhelaban soberanía, identidad e igualdad. Una etapa difícil, como todos los procesos que persiguen las transformaciones sociales, en pro de un mundo donde prevalezca la justicia y se respete la dignidad del ser humano.
FACTORES DE RIESGO DE OBESIDAD Y SOBREPESO EN EL PERSONAL DOCENTE UNIVERSITARIO. BARQUISIMETO ESTADO LARA. VENEZUELA
Bencomo, María Ninón,Dugarte Fernández Nelly,Berríos Rivas, Ana Teresa,Blanco Manuel Ramón
Salud, Arte y Cuidado , 2011,
Abstract: For determining the risk factors of obesity and overweight in the faculty of medicine and nursing programs of the Dean of Health Sciences, designed a field study descriptive, not experimental, we studied 55 regular active teachers, who are underwent clinical evaluation, anthropometric, biochemical, nutritional and socio-environmental, demographic data to investigate further. The most significant results were: 80% were located in aged ≤ 40 years and 20%> 40 years, the average age was 46 years with a standard deviation of 7.157, 84% were female and 16% were male, the nutritional diagnosis according to Body Mass Index (BMI) left to see a high percentage (67%) of overweight (23% obese, 44% overweight), the abdominal circumference (AC) associated with abdominal obesity and gender, percentage was higher in women than in men. As for the practice of physical activity, showed that a high percentage of teachers 81.8% said no physical activity. The teachers spend the wee hours of television and computer time. Fast food consumption and food consumption outside the home was present in more than 40% of teachers. These results allow us to conclude that the scourge of obesity and overweight increased daily gain prominence and interest to the health professional, for his social influence and bias in adult life. It is recommended to propose educational strategies through workshops and recreational activities aimed at reducing the high frequency of overweight staff evident in the Dean of Health Sciences at UC
Evaluación de la quimioprofilaxis con zidovudine a la mujer embarazada VIH(+) y su hijo (Uruguay)
Quian,Jorge; Picón,Teresa; Rodríguez,Irene; Gutiérrez,Stella; González,Alicia; Nin,Margarita; Galazka,Jeanette; Martín,Jacqueline; Galeano,Virginia; Cafferata,María Luisa; Russi,José; Pérez,María Teresa; Ruchansky,Dora;
Revista chilena de pediatría , 2001, DOI: 10.4067/S0370-41062001000100013
Abstract: actg 076 protocol results about zidovudine (azt) quimioprofilaxis (qp) in order to reduce vih vertical trasmission, were published in 1994, pregnant women who received azt, gad a 8.4% transmission, compared with 24% of the ones who received placebo. objetive: evaluate azt qp results. methods: 304 mother-child couple histories, from pereira rossell hospital, were retrospectively analized since june, 1990 to december, 1998. complete qp was defined when hiv (+) pregnant women received oral azt during one month or more before delivery, i/v azt while delivery labor and when the newborno received during the first six weeks. incomplete qp was defined when one or two parts of the complete treatment has failed. children were clasified as: seroreverted (s), infected (i), perinatal exposes (e) following c.d.c. criteria. results: until december, 1994, 116 mother-child couple were studied and vertical transmission were found in 28.4%. in 1995, in 39 couples transmission was 29.03%. no couple received complete qp and 5 (15.6%) received incomplete qp. in 1996, in 60 couples, transmission was 31.6%, 7 of then (11.66%) received complete qp, and 22 (36 %) received incomplete qp. in 117, in 50 couples, transmission was 12%, 26 of then (52.9%) received complete qp, and 16 (31.3%) incomplete qp. in 1998 in 47 couples, transmission was 8.5%, 31 of then (65%) received complete qp, a 14 (29.78%) incomplete qp. since january, 1995, 64 couples received complete qp, transmission was 6.25%, 57 couples received incomplete qp and transmission was 8.7%. in couples without qp, transmission was 43.2%. conclusions: since 1995, the number of couples that received azt qp had a progresive increase, with a favourable impact in non infected newborns. vih vertical transmission prevention obtained important results in uruguay. to disminish infected children, and an adecquated cost-benefit relationship must be the objective for 100% mother-child couples.
Risk Factors Associated with Malnutrition Caused by Over-consumption in Adolescents Factores de riesgo asociados con malnutrición por exceso en adolescentes
David Yunior Velasco Pe?a,Osmany álvarez Paneque,Yamilé Marí Nin,Andrés Andrés
Finlay : Revista de Enfermedades no Transmisibles , 2012,
Abstract: Introduction: obesity and overweight are currently a considerable health problem for children and adolescents in Cuba. Objective: to determine risk factors associated with malnutrition caused by over-consumption in the Julio Grave de Peralta Polyclinic, in Holguín, from August 2011 to February 2012. Methods: a transversal analytical study was performed including 37 adolescents aged from 15 to 19 years old. The variables analyzed in the study were: sex, nutritional assessment, blood pressure, total cholesterol and triglycerides. For comparative analysis we used the chi-square test. In all cases, we worked with a significance level of p <0,05. Results: obesity was found in 24, 32 % of adolescents and was more common in females. In the group of patients with malnutrition caused by overweight, 12 had pathological family history of obesity (80 %), X2 = 13, 87. These adolescents presented high levels of cholesterol and triglycerides and 20 % of them suffered from grade I hypertension. A significant association was found between malnutrition and excessive levels of cholesterol and triglycerides. Conclusions: the pathological family history of obesity, high cholesterol and triglycerides and high blood pressure emerged as risk factors associated with overweight in the teenagers included in the study. Introducción: en la actualidad la obesidad y el sobrepeso son un importante problema de salud para los ni os y adolescentes cubanos. Objetivo: determinar algunos factores de riesgo asociados con malnutrición por exceso en adolescentes del policlínico Julio Grave de Peralta de la provincia Holguín durante el periodo de agosto del 2011 a febrero del 2012. Métodos: se realizó un estudio analítico y transversal. Se estudiaron 37 adolescentes entre 15-19 a os. Las variables analizadas en el estudio fueron: sexo, evaluación nutricional, presión arterial, colesterol total y triglicéridos. Para el análisis comparativo se empleó el test de Chi cuadrado. En todos los casos, se trabajó con un nivel de significación de p < 0,05. Resultados: se encontró obesidad en el 24,32 % de los adolescentes y fue más frecuente en el sexo femenino. En el grupo de pacientes con malnutrición por exceso 12 presentaron antecedentes patológicos familiares de obesidad (80 %), X2 = 13,87. Los adolescentes con malnutrición por exceso tuvieron altos niveles de colesterol y triglicéridos. El 20 % de los adolescentes con malnutrición por exceso presentó hipertensión grado I. Se encontró asociación significativa entre la malnutrición por exceso y los niveles elevados de colesterol y triglicéridos. Concl
Determinantes genéticos del riesgo y pronóstico del da o renal agudo: una revisión sistemática Genetic determinants of acute renal damage risk and prognosis: a systematic review
P. Cardinal-Fernández,A. Ferruelo,A. Martín-Pellicer,N. Nin
Medicina Intensiva , 2012,
Abstract: Introducción: El da o renal agudo (DRA) es un síndrome frecuente en el paciente hospitalizado. Los factores de riesgo asociados a su desarrollo y evolución clásicamente aceptados se encuentran en relación con el ambiente o la enfermedad de base del paciente. Sin embargo, en los últimos a os se ha reconocido la influencia de los factores genéticos. Objetivo: Analizar la influencia de los polimorfismos genéticos en el riesgo de presentar y en la evolución del DRA. Fuente de datos: búsqueda electrónica en MEDLINE. Selección de estudios: manuscritos redactados en idioma inglés o espa ol, publicados entre el 1/1/1995 y el 31/5/2011 y que analizaron la asociación entre polimorfismos genéticos y: (a) susceptibilidad a DRA entre pacientes versus controles sanos o entre diferentes grupos de pacientes; (b) gravedad del DRA. Criterios de exclusión: estudios publicados solo en forma de resumen, casos clínicos o estudios que incluyeran pacientes menores de 16 a os, en diálisis crónica o con trasplante renal. Extracción de datos: al menos uno de los investigadores analizó cada artículo mediante formulario predefinido. Resultados: Se encontraron 12 trabajos que incluyeron 4.835 pacientes. Once genes contienen polimorfismos asociados a la susceptibilidad o gravedad del DRA. Hemos clasificado estos genes de acuerdo con su función en aquellos que participan en la respuesta hemodinámica (ACE, eNOS, FNMT y COMT), respuesta inflamatoria (TNFα, IL10, IL6, HIP-1A, EPO), estrés oxidativo (NAPH oxidasa) y en el metabolismo lipídico (APOE). Solo los genes de APOE, ACE y receptor AT1 han sido analizados en más de un estudio. Conclusión: La susceptibilidad y gravedad del DRA están relacionadas con factores genéticos que están implicados en distintos mecanismos fisiopatológicos. Introduction: Acute renal damage (ARD) is a frequent syndrome in hospitalized patients. It is well accepted that ARD susceptibility and outcome are related to environmental risk factors and to the patient premorbid status. Recently, host factors have also been recognized as important in ARD predisposition and evolution. Objective: To analyze genetic influences related to the risk and severity of ARD. Data sour MEDLINE search. Selection of studies: articles published in English or Spanish between 1/1/1995 and 31/5/2011, analyzing the association between genic polymorphisms and (a) ARD susceptibility in patients versus healthy controls or within groups of patients; or (b) ARD severity. Exclusion criteria: studies published only in abstract form, case reports or including patients less than 16 years of age, on
Rats surviving after high tidal volume ventilation show marked and reversible pulmonary and systemic changes
O Pe?uelas, N Nin, M De Paula, P Fernandez-Segoviano, J Lorente, A Esteban
Critical Care , 2006, DOI: 10.1186/cc4353
Abstract: Normal anesthetized Sprague-Dawley rats were tracheostomized and ventilated for 1 hour with either VT = 9 ml/kg + PEEP 5 cmH2O, or VT = 35 ml/kg + ZEEP. After the HTVV period, the tracheostomy was closed, and rats were sent back to their cages breathing room air. Other rats were sacrificed at this point in time (t = 1 hour). Rats surviving the acute period of HTVV were again intubated, monitored and then sacrificed at different points in time (24 hours, 72 hours, 168 hours). We measured the mean arterial pressure, aortic blood flow (QAo), arterial blood gases, and total protein, AST, ALT, IL-6, and VEGF serum and BAL fluid concentrations. Aortic segments and pulmonary micro vessels were mounted in myographs, and responses to acetylcholine in norepinehrine-precontracted rings were tested. Histological lung changes were studied.All lungs showed diffuse alveolar damage after HTVV at 1 and 24 hours, but histology was completely normal at t = 72 hours. HTVV induced hypotension, decreased QAo, hypoxemia, increased protein, AST, ALT, IL-6, and VEGF BAL fluid/serum concentration ratio. Acetylcholine and norephineprine-induced responses were impaired after HTVV in aortic rings. Moreover acetylcholine-induced responses in pulmonary microvessels were impaired. All these biochemical and vascular function changes normalized at t = 168 hours.About half the rats receiving for a short period of time ventilation using very high VT survive. HTVV induces in a reversible fashion pulmonary and systemic inflammation and vascular dysfunction.Funded by FIS CO3/11, GO3/063.
Lesión pulmonar aguda y síndrome de distrés respiratorio agudo: una perspectiva genómica
Cardinal-Fernández,P.; Nin,N.; Lorente,J.A.;
Medicina Intensiva , 2011,
Abstract: genomics have allowed important advances in the knowledge of the etiology and pathogenesis of complex disease entities such as acute lung injury (ali) and acute respiratory distress syndrome (ards). genomic medicine aims to personalize and optimize diagnosis, prognosis and treatment by determining the influence of genetic polymorphisms in specific diseases. the scientific community must cope with the important challenge of securing rapid transfer of knowledge to clinical practice, in order to prevent patients from becoming exposed to unnecessary risks. in the present article we describe the main concepts of genomic medicine pertaining to ali/ards, and its currently recognized clinical applications.
Lesión pulmonar aguda y síndrome de distrés respiratorio agudo: una perspectiva genómica Acute lung injury and acute respiratory distress syndrome: a genomic perspective
P. Cardinal-Fernández,N. Nin,J.A. Lorente
Medicina Intensiva , 2011,
Abstract: Recientemente la genómica ha adquirido una enorme relevancia, permitiendo sustanciales avances en el conocimiento de la etiología y patogenia de entidades complejas como la lesión pulmonar aguda (LPA) y el síndrome de distrés respiratorio agudo (SDRA). La medicina genómica procura personalizar y optimizar el diagnóstico, pronóstico y tratamiento mediante el reconocimiento de la influencia que ejercen los polimorfismos genéticos en enfermedades específicas. Uno de los principales desafíos que la comunidad científica debe afrontar es lograr que este conocimiento sea transferido pertinente y rápidamente a la práctica clínica. En caso contrario, es posible que los pacientes sean sometidos a un riesgo innecesario. En el presente artículo se describen los principales aspectos de la medicina genómica en la LPA/SDRA y cuáles son las aplicaciones clínicas actuales. Genomics have allowed important advances in the knowledge of the etiology and pathogenesis of complex disease entities such as acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Genomic medicine aims to personalize and optimize diagnosis, prognosis and treatment by determining the influence of genetic polymorphisms in specific diseases. The scientific community must cope with the important challenge of securing rapid transfer of knowledge to clinical practice, in order to prevent patients from becoming exposed to unnecessary risks. In the present article we describe the main concepts of genomic medicine pertaining to ALI/ARDS, and its currently recognized clinical applications.
Paracetamol: ?Adictivo? Presentación de un caso
García González,Yamilet; Fernández Nin,María Victoria; Torriente Valle,Maggie; Díaz Rodríguez,Dianelys;
Revista Cubana de Medicina Militar , 2010,
Abstract: in present paper is presented the case of a male adolescent who after a bone pain started by medical prescription a treatment with non-steroids anti-inflammatory drugs. first the ibuprofen was prescribed, which was substituted at several weeks by acetaminophen which it is used for symptomatic treatment of pain and fever. patient was studied and there was not a structured additive disease, although with a positive risk of develop it. neither there was a visible hepatic damage. was treated with a favorable course.
Paracetamol: Adictivo? Presentación de un caso Paracetamol: Addictive? A case presentation
Yamilet García González,María Victoria Fernández Nin,Maggie Torriente Valle,Dianelys Díaz Rodríguez
Revista Cubana de Medicina Militar , 2010,
Abstract: En este trabajo se presenta a un adolescente masculino quien, tras un dolor óseo, inició por indicación médica tratamiento con antiinflamatorios no esteroideos. Primeramente le fue indicado ibuprofeno, el cual fue sustituido a las semanas por paracetamol, medicamento que se utiliza para el tratamiento sintomático del dolor y la fiebre. El paciente fue estudiado y no se detectó una enfermedad adictiva estructurada, aunque sí riesgo de desarrollarla. Tampoco se encontró un aparente da o hepático. Recibió tratamiento y la evolución fue favorable. In present paper is presented the case of a male adolescent who after a bone pain started by medical prescription a treatment with non-steroids anti-inflammatory drugs. First the Ibuprofen was prescribed, which was substituted at several weeks by Acetaminophen which it is used for symptomatic treatment of pain and fever. Patient was studied and there was not a structured additive disease, although with a positive risk of develop it. Neither there was a visible hepatic damage. Was treated with a favorable course.
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