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Search Results: 1 - 10 of 37589 matches for " Mar Masiá "
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Usos de la tierra y distribución de la materia orgánica particulada béntica en ríos de monta?a (Patagonia, Argentina)
Masi,Carolina Isabel; Miserendino,María Laura;
Ecolog?-a austral , 2009,
Abstract: worldwide, there is a strong concern about how land use changes are affecting the ecological integrity of aquatic resources. in this paper, we examined the distribution of different items of benthic particulate organic matter and chlorophyll 'a' in 18 patagonian mountain rivers subjected to different land use types: pastures, exotic pine plantations, urban, reference urban, managed native forest, and undisturbed native forest. different items of detritus were obtained from samples in pools and riffles, whereas chlorophyll was quantified in runs. coarse particulate organic matter was significantly higher in forested sites than in pasture sites. particulate organic matter was rich in wood biomass and fragmented material in native forests, whereas managed native forest were rich in leaf biomass. chlorophyll did not exhibit any consistent pattern among land use types. bryophyte biomass was significantly higher in native forests, while macrophyte biomass was significantly higher in the urban land use. at the habitat scale, riffles supported higher leaf biomass and bryophytes than pools. land use practices in patagonia resulted in differences in the allochthonous detritus supply and the autotrophic production (bryophytes and macrophytes). the re-establishment of woody species and retention of patches of native forest in riparian corridors can ameliorate the lack of coarse particulate organic matter in rivers under pastoral development. the proper disposal of post harvest material from forest clearing and the restriction of livestock accesses to the channel will improve the ecological conditions of the banks as well as the in-stream habitat.
Contribution of Interferon gamma release assays testing to the diagnosis of latent tuberculosis infection in HIV-infected patients: A comparison of QuantiFERON-TB Gold In Tube, T-SPOT.TB and tuberculin skin test
Ramos José M,Robledano Catalina,Masiá Mar,Belda Sofia
BMC Infectious Diseases , 2012, DOI: 10.1186/1471-2334-12-169
Abstract: Background Diagnosis and treatment of latent tuberculosis infection (LTBI) is the most effective strategy to control tuberculosis (TB) among patients with HIV infection. The tuberculin skin test (TST) was the only available method to identify LTBI. The aim of the present work was to evaluate the usefulness of the interferon-gamma release assays (IGRAs): QuantiFERON-tuberculosis (TB) Gold-In-Tube test (QFG) and T-SPOT.TB for the diagnosis of LTBI in a diverse cohort of HIV-infected patients. Methods A prospective study was carried out in consecutive patients cared for in a single institution in Spain from January 2009 to October 2010. IGRAs and TST were performed simultaneously. TST induration ≥ 5 mm was considered positive. Results QFG, T-SPOT.TB and TST were performed in 373 subjects. Median CD4 cell count was 470/μl with a median nadir of 150/μl. TST, QFG and T-SPOT.TB were positive in 13.3%, 7.5% and 18.5% cases respectively. Among 277 patients with neither past or current TB nor previous treatment for LTBI and who had TST results, a positive TST result was obtained in 20 (7.2%) cases. When adding QFG results to TST, there were a total of 26 (8.6%) diagnoses of LTBI. When the results of both IGRAs were added, the number of diagnoses increased to 54 (17.9%) (incremental difference: 10.7% [95% confidence interval [CI]:5.3-16.2%] [p < 0.001]), and when both IGRAs were added, the number of diagnoses reached 56 (18.5%) (incremental difference: 11.3% [95% CI:5.7%–16.9%] [p < 0.001]). Patients with a CD4 cell count greater than 500 cells/μl and prior stay in prison were more likely to have a diagnosis of LTBI by TST and/or QFG and/or T-SPOT.TB (adjusted odds ratio [aOR]: 3.8; 95% CI, 1.4 – 9.9; and aOR: 3.3; 95% CI, 1.3 – 8.3, respectively). Conclusions IGRAs were more sensitive than TST for diagnosis of M. tuberculosis infection in HIV-infected patients. Dual sequential testing with TST and IGRAs may be the optimal approach for LTBI screening in this population.
Evaluation of endothelial function and subclinical atherosclerosis in association with hepatitis C virus in HIV-infected patients: a cross-sectional study
Mar Masiá, Sergio Padilla, Catalina Robledano, José M Ramos, Félix Gutiérrez
BMC Infectious Diseases , 2011, DOI: 10.1186/1471-2334-11-265
Abstract: Flow-mediated dilatation (FMD) of the brachial artery and circulating levels of cell adhesion molecules (CAM) were measured in HCV/HIV-coinfected and HIV-monoinfected patients. Subclinical atherosclerosis was assessed by carotid intima-media thickness (cIMT).63 (31%) HCV/HIV-coinfected and 138 (69%) HIV-monoinfected patients were included. Median soluble vascular CAM-1 (sVCAM-1) and intercellular CAM-1 (sICAM-1) levels were significantly higher in HIV/HCV-coinfected patients (P < 0.001 for both cases). Median (interquartile range) FMD was 6.21% (2.86-9.62) in HCV/HIV-coinfected and 5.54% (2.13-9.13) in HIV-monoinfected patients (P = 0.37). Adjustment for variables associated with HCV and FMD disclosed similar results. FMD correlated inversely with cIMT and age. Carotid IMT did not differ between HCV/HIV-coinfected and HIV-monoinfected patients in unadjusted (0.61 [0.55-0.65] mm vs 0.60 [0.53-0.72] mm; P = 0.39) or adjusted analyses.HCV infection was associated with higher levels of sICAM-1 and sVCAM-1, but no evidence of increased subclinical atherosclerosis was found when endothelial function was evaluated through FMD, or when assessing the cIMT.Relationship of hepatitis C virus (HCV) infection with an increased risk of cardiovascular disease (CVD) in HIV-infected patients remains controversial. While data from large cohort studies support a higher frequency of cardiovascular events in these patients [1,2], other studies have shown differing results [3], and no increased subclinical atherosclerosis measured with the carotid intima-media thickness (cIMT) was found in a large cohort of HCV/HIV-coinfected compared with HIV-monoinfected women [4].Endothelial dysfunction (ED) is an early event in the development of atherosclerosis [5,6]. HCV/HIV-coinfection has been associated with ED in a study based in the measurement of circulating cell adhesion molecules (CAM) levels [7]. Likewise, a sustained decrease in CAM levels (intercellular CAM-1 [ICAM-1] and vascular CAM-1 [
Early changes in inflammatory and pro-thrombotic biomarkers in patients initiating antiretroviral therapy with abacavir or tenofovir
Authors: Padilla, Mar Masiá, Natalia García, Inmaculada Jarrin, Consuelo Tormo, Félix Gutiérrez
BMC Infectious Diseases , 2011, DOI: 10.1186/1471-2334-11-40
Abstract: Consecutive patients initiating antiretroviral therapy (ART) with abacavir/lamivudine or tenofovir/emtricitabine were included. Plasma levels of high sensitivity C reactive protein (hsCRP), interleukin-6 (IL-6), intercellular adhesion molecule-1, vascular cell adhesion molecule-1 (sVCAM-1) and plasminogen activator inhibitor-1 (PAI-1) were measured at baseline and at different time points throughout 48 weeks. Comparisons were adjusted for age, sex, ART status at inclusion, viral load, lipodystrophy, Framingham score and hepatitis C virus co-infection status.50 patients were analyzed, 28 initiating abacavir and 22 tenofovir. The endothelial biomarker sVCAM-1 declined significantly in both treatment groups. hsCRP tended to increase soon after starting therapy with abacavir, a trend that was not seen in those initiating tenofovir. IL-6 significantly increased only at week 24 from baseline in patients on abacavir (+225%, p < 0.01) although the differences were not significant between groups. The procoagulant biomarker PAI-1 plasma levels increased from baseline at week 12 (+57%; p = 0.017), week 24 (+72%; p = 0.008), and week 48 (+149%; p < 0.001) in patients on tenofovir, but differences between groups were not statistically significant.Changes in biomarkers of inflammation, coagulation, and endothelial function are not different in viremic patients starting ART with abacavir/lamivudine or tenofovir/emtricitabine. These changes occur in the early phases of treatment and include anti- and pro-atherosclerotic effects with both drugs.Current or recent use of abacavir has been associated with an increased risk of developing acute myocardial infarction (MI) in the D:A:D cohort study [1] and in observational data derived from the SMART trial [2]. The excess risk of cardiovascular disease (CVD) did not seem to be explained by the underlying cardiovascular risk factors and was no longer present in patients who had stopped abacavir for more than 6 months [1], suggesting an acut
Comparison between telephone and self-administration of Short Form Health Survey Questionnaire (SF-36)
García,María; Rohlfs,Izabella; Vila,Joan; Sala,Joan; Pena,Araceli; Masiá,Rafael; Marrugat,Jaume; ,;
Gaceta Sanitaria , 2005, DOI: 10.1590/S0213-91112005000600003
Abstract: objective: the characteristics of the 36 item medical outcome short form health study survey (sf-36) questionnaire, designed as a generic indicator of health status for the general population, allow it to be self-administered or used in personal or telephone interviews. the main objective of the study was to compare the telephone and self-administered modes of sf-36 for a population from girona (spain). methods: a randomized crossover administration of the questionnaire design was used in a cardiovascular risk factor survey. of 385 people invited to participate in the survey, 351 agreed to do so and were randomly assigned to two orders of administration (i.e., telephone-self and self-telephone); 261 completed both questionnaires. scores were compared between administration modes using a paired t test. internal consistency and agreement between modalities were analyzed by respectively applying chronbach's alpha and intraclass correlation coefficients. the effect of the order of administration on the test-retest difference was analyzed by one-way anova for repeated measurements. results: physical function, physical role and social functioning received significantly lower scores when the self-administered questionnaire was used prior to the telephone survey. when the initial survey was conducted by telephone, all chronbach's alpha coefficients (except social functioning) scored over 0.70 in the self-administered modality. the intraclass correlation coefficient ranged from 0.41 to 0.83 for the telephone-self order and from 0.32 to 0.73 for the self-telephone order. no clinically significant effect was observed for the order of application. conclusions: the results of the present study suggest that the telephone-administration mode of sf-36 is equivalent to and as valid as the self-administered mode.
Dignidad humana y situaciones terminales
Anales del Sistema Sanitario de Navarra , 2007, DOI: 10.4321/S1137-66272007000600004
Abstract: dignity should not be confused with the unbecoming conditions that a person can find himself in due to external situations or disease. the person/patient in a terminal situation has human dignity, which must be respected not because he/she is a terminal patient but simply because he/she is a person. but it is true that in terminal situations dignity can be particularly threatened. nonetheless, one must not deduce from the criterion of respecting dignity the conclusion of prolonging biological life at all costs, but instead that of guaranteeing the best quality of living during the process of dying and of worthily accompanying the person who is approaching death by helping him to accept this.
Dignidad humana y situaciones terminales Human dignity and terminal situations
J. Masiá
Anales del Sistema Sanitario de Navarra , 2007,
Abstract: No hay que confundir la dignidad con las condiciones indignas en que puede encontrarse una persona por circunstancias exteriores o por la enfermedad. La persona paciente en situación terminal tiene dignidad humana, que exige ser respetada, no por ser paciente terminal, sino simplemente por ser persona. Pero es cierto que en situaciones terminales puede verse particularmente amenazada la dignidad. Sin embargo, no se debe deducir del criterio de respetar la dignidad la conclusión de prolongar la vida biológica a toda costa, sino la de garantizar la mejor calidad del vivir durante el proceso de morir y de acompa ar dignamente a la persona que se aproxima a la muerte ayudándole a asumirla. Dignity should not be confused with the unbecoming conditions that a person can find himself in due to external situations or disease. The person/patient in a terminal situation has human dignity, which must be respected not because he/she is a terminal patient but simply because he/she is a person. But it is true that in terminal situations dignity can be particularly threatened. Nonetheless, one must not deduce from the criterion of respecting dignity the conclusion of prolonging biological life at all costs, but instead that of guaranteeing the best quality of living during the process of dying and of worthily accompanying the person who is approaching death by helping him to accept this.
Jaume Masià
Cirugía Plástica Ibero-Latinoamericana , 2006,
Generalized information-entropy measures and Fisher information
Marco Masi
Physics , 2006,
Abstract: We show how Fisher's information already known particular character as the fundamental information geometric object which plays the role of a metric tensor for a statistical differential manifold, can be derived in a relatively easy manner through the direct application of a generalized logarithm and exponential formalism to generalized information-entropy measures. We shall first shortly describe how the generalization of information-entropy measures naturally comes into being if this formalism is employed and recall how the relation between all the information measures is best understood when described in terms of a particular logarithmic Kolmogorov-Nagumo average. Subsequently, extending Kullback-Leibler's relative entropy to all these measures defined on a manifold of parametrized probability density functions, we obtain the metric which turns out to be the Fisher information matrix elements times a real multiplicative deformation parameter. The metrics independence from the non-extensive character of the system, and its proportionality to the rate of change of the multiplicity under a variation of the statistical probability parameter space, emerges naturally in the frame of this representation.
On the extended Kolmogorov-Nagumo information-entropy theory, the q -> 1/q duality and its possible implications for a non-extensive two dimensional Ising model
Marco Masi
Physics , 2006, DOI: 10.1016/j.physa.2006.11.019
Abstract: The aim of this paper is to investigate the q -> 1/q duality in an information-entropy theory of all q-generalized entropy functionals (Tsallis, Renyi and Sharma-Mittal measures) in the light of a representation based on generalized exponential and logarithm functions subjected to Kolmogorov's and Nagumo's averaging. We show that it is precisely in this representation that the form invariance of all entropy functionals is maintained under the action of this duality. The generalized partition function also results to be a scalar invariant under the q -> 1/q transformation which can be interpreted as a non-extensive two dimensional Ising model duality between systems governed by two different power law long-range interactions and temperatures. This does not hold only for Tsallis statistics, but is a characteristic feature of all stationary distributions described by q-exponential Boltzmann factors.
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