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Search Results: 1 - 10 of 965 matches for " Manorama;Arora "
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Role of the Parasight-F test in the diagnosis of complicated Plasmodium falciparum malarial infection
Arora, Sandeep;Gaiha, Manorama;Arora, Anju;
Brazilian Journal of Infectious Diseases , 2003, DOI: 10.1590/S1413-86702003000500008
Abstract: an evaluation was made of the diagnostic efficacy and utility of the parasight-f test in diagnosing plasmodium falciparum malaria, compared with conventional microscopy, particularly in severe and complicated cases. this study was designed as a prospective, case control hospital-based study. febrile patients suspected to be suffering from malaria were selected randomly and were subjected to peripheral smear examinations (thick and thin) and parasight-f tests till the required number of at least 30 cases of p. falciparum infection were identified, including at least 15 complicated cases. in addition 20 cases of p. vivax malarial infection as well as 20 healthy age and sex-matched individuals were taken as two control groups. the outcome measure was the number of cases with positive parasight-f test results compared with conventional microscopy. thirty-two patients with p. falciparum malaria were identified, with 15 severe and complicated cases. peripheral smears were positive in 29 (91%) of these, while parasight-f test was positive in 31 out of 32 (97%) cases. parasites were detected only by bone marrow examination in one case. diagnostic sensitivity and specificity of peripheral smears for detecting falciparum infection were 90.6% and 100% respectively while that of the parasight-f test were 96.8% and 100%, respectively (p>.05). the parasight-f test has high sensitivity and specificity in diagnosing p. falciparum malarial infection, comparable to or even higher than microscopy exams, particularly in severe and complicated cases, with additional advantages of speed, simplicity and objectivity.
Role of the Parasight-F test in the diagnosis of complicated Plasmodium falciparum malarial infection
Arora Sandeep,Gaiha Manorama,Arora Anju
Brazilian Journal of Infectious Diseases , 2003,
Abstract: An evaluation was made of the diagnostic efficacy and utility of the Parasight-F test in diagnosing Plasmodium falciparum malaria, compared with conventional microscopy, particularly in severe and complicated cases. This study was designed as a prospective, case control hospital-based study. Febrile patients suspected to be suffering from malaria were selected randomly and were subjected to peripheral smear examinations (thick and thin) and Parasight-F tests till the required number of at least 30 cases of P. falciparum infection were identified, including at least 15 complicated cases. In addition 20 cases of P. vivax malarial infection as well as 20 healthy age and sex-matched individuals were taken as two control groups. The outcome measure was the number of cases with positive Parasight-F test results compared with conventional microscopy. Thirty-two patients with P. falciparum malaria were identified, with 15 severe and complicated cases. Peripheral smears were positive in 29 (91%) of these, while parasight-F test was positive in 31 out of 32 (97%) cases. Parasites were detected only by bone marrow examination in one case. Diagnostic sensitivity and specificity of peripheral smears for detecting falciparum infection were 90.6% and 100% respectively while that of the Parasight-F test were 96.8% and 100%, respectively (P>.05). The Parasight-F test has high sensitivity and specificity in diagnosing P. falciparum malarial infection, comparable to or even higher than microscopy exams, particularly in severe and complicated cases, with additional advantages of speed, simplicity and objectivity.
Efficacy of Slow Reversal Hold and Isometrics in Improving Muscle Strength, Increasing Range of Motion, and Reducing Pain in Patients with Osteoarthritis of Knee  [PDF]
Harneet Arora
Health (Health) , 2018, DOI: 10.4236/health.2018.105043
Abstract: Osteoarthritis of knee is a common problem in the elderly population worldwide. Physical therapy has been shown to be useful in decreasing pain and increasing mobility in this population. The aim of this study was to study the effectiveness of slow reversal hold and isometric exercise techniques in reducing pain, increasing muscle strength, and increasing range of motion for knee flexion in patients with osteoarthritis of knee. The other aim of this study was to compare the relative effectiveness of these two interventions. 60 subjects participated in this study and were randomly assigned either to the slow reversal hold group (n = 30) or, to the isometrics exercise group (n = 30). All subjects performed their respective exercises for 3 weeks. Pain scores using the visual analog scale, muscle strength using manual muscle testing of quadriceps and hamstrings, and range of motion (ROM) for knee flexion using a goniometer were recorded both pre-treatment and post-treatment for both left and right knees. Both the interventions showed a significant decrease in pain scores, an increase in muscle strength, as well as an increase in the ROM. However, ROM was significantly increased in the slow reversal hold group as compared to the isometrics group in both knees. It was concluded that both exercise techniques could be useful in patients with osteoarthritis of knee for decreasing pain and increasing muscle strength. Slow reversal hold technique might be a better technique than isometrics for increasing ROM for knee flexion.
Risk of high gestational weight gain on adverse pregnancy outcomes  [PDF]
Rajin Arora, Darin Arora, Jayanton Patumanond
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.31A027
Abstract:

Background/Aims: Excessive gestational weight gain was known to be associated with adverse pregnancy outcomes. It increased the complications during pregnancy, delivery and postpartum period. Nevertheless, there are studies reporting the incompliance of pregnant women with recommendations of weight gain. The objectives of this study were to estimate the prevalence of high gestational weight gain and to identify the increased adverse pregnancy outcomes in these women. Methods: This was a cross sectional study. Data were collected retrospectively from hospital electronic database of Lampang Regional Hospital (LPH) along with manual retrieval from medical charts and labor records. Data of all pregnant women who delivered at labor room of LPH were collected from 1st February 2011 to 31st August 2012. After preterm and multifetal pregnancies were excluded, 4747 cases were brought to the study. This study used the new weight gain recommendation from the Institute of Medicine and National Research Council to classify pregnant women by pre-pregnancy body mass index. Data were analyzed by univariate and multivariate analysis. Results: The proportions of pregnant women with different level of weight gain were 28.4%, 38.5% and 33.1% for low, normal and high weight gain. After multivariate analysis was done to control the confounders, women with high weight gain were significantly correlated with having preeclampsia, higher birth weight group, cesarean section and long neonatal length with relative risk (RR) and 95% confidence interval (95% CI) of 4.84 (2.31 - 10.16), 3.94 (3.24 - 4.79), 2.12 (1.82 - 2.47) and 2.33 (1.90 - 2.86). Conclusions: There were more than half of pregnant women that were prone to have inappropriate weight gain. Many complications from high weight gain that have been reported from aboard also occurred in Thai pregnant women. This should alert corresponding health institute to establish a new guideline to avoid high gestational weight gain.

Adverse pregnancy outcomes in women with high pre-pregnancy body mass index  [PDF]
Rajin Arora, Darin Arora, Jayanton Patumanond
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.32053
Abstract:

Background/Aims: Obesity along with high prepregnancy body mass index (PP-BMI) is known to cause many adverse pregnancy outcomes. In Thailand, there is not much study showing both the prevalence and complications of these conditions. The objectives of this study were to estimate the prevalence of prepregnancy overweight and obesity and their impacts on adverse pregnancy outcomes. Methods: This study was a cross sectional study. Data were collected retrospectively from hospital electronic database along with manual retrieval from medical charts and labor records. Data of all delivery women from 1st February 2011 to 31st August 2012 were collected. When excluded cases with incomplete data and those without PP-BMI, 5420 cases were into analysis. Descriptive and inferential data analyses were used with both univariate and multivariate methods. Results: The proportion of pregnant women with overweight and obesity were 11.1% and 3.9%. After multiple logistic regression analysis was done, women in obesity group were correlated with having 1, 2 and 3 complications. They were also correlated with preeclampsia, gestational diabetes, cesarean section, higher birth weight group and long neonatal length. Conclusions: This Thai prevalence of obesity in pregnancyshould alarm health care providers to be more prepared, for a future health problem of the country. Many complications that come with obese pregnant women that were reported in western countries also happen in Thai population. Decreasing body weight before conception, giving correct health education, well planned pregnancy; antenatal lifestyle intervention and even gestational weight gain restricttion could help avoiding these uneventful morbidities.

High pre-delivery body mass index also caused adverse pregnancy outcomes  [PDF]
Rajin Arora, Darin Arora, Jayanton Patumanond
Open Journal of Obstetrics and Gynecology (OJOG) , 2013, DOI: 10.4236/ojog.2013.34076
Abstract:

Background/Aims: It is known that high pre-preg-nancybody mass index (BMI) and high gestational weight gain both can cause many adverse pregnancy outcomes. High pre-delivery BMI (PD-BMI), though theoretically could do similar effects, is rarely been studied. The objectives of this study were to show the distribution of PD-BMI of the delivery women and to identify its correlation with adverse pregnancy outcomes. Methods: This study was a cross sectional study. Data were collected retrospectively from hospital electronic database of Lampang Regional Hospital (LPH) along with manual retrieval from medical charts and labor records. Data of all pregnant women who delivered at labor room were collected from 1st February 2011 to 31st August 2012. After preterm and multifetal pregnancies were excluded, 4999 cases were into the analysis. Descriptive and inferential data analyses were used with both univariate and multivariate methods. Results: In this group of women, 93.9% were in the PD-BMI range of 20.0 -34.9 kg/m2. After multivariate analysis was used, higher PD-BMI was shown to be correlated with higher cesarean section, neonates weighing ≥3500 gmand long neonatal length with relative risk (RR) and 95% confidence interval (95% CI) of 1.11 (1.09 - 1.13), 1.15 (1.12 - 1.17) and 1.07 (1.05 - 1.09), respectively. Conclusions: High PD-BMI was correlated with multiple adverse pregnancy outcomes. Interestingly, their effect sizes were much smaller comparing to high pre-pregnancy BMI and high gestational weight gain. It confirmed the current recommendations to monitor pre-pregnancy BMI and gestational weight gain to avoid unwanted morbidities.

Bevacizumab-Induced Reversible Thrombocytopenia in a Patient with Adenocarcinoma of Colon: Rare Adverse Effect of Bevacizumab
Jeevan Kumar,Manorama Bhargava,Shyam Aggarwal
Case Reports in Oncological Medicine , 2012, DOI: 10.1155/2012/695430
Abstract: We report a case of bevacizumab- (BEV-) induced thrombocytopenia in a 59-year-old man with adenocarcinoma of colon. After colectomy, the patient was treated with twelve cycles of FOLFOX-4 (folinic acid, 5-fluorouracil, and oxaliplatin) regimen. On relapse, he was treated with FOLFIRI (folinic acid, 5-fluorouracil, and irinotecan) regimen along with BEV 10 mg/kg for 6 cycles. After that, BEV was continued for maintenance as a single agent at an interval of three weeks. After the13th cycle of BEV, the patient developed melena with epistaxis and thrombocytopenia, from which he recovered on withdrawal of BEV. On rechallenge with half the initial dose, there was once again a reversible drop in platelet count. The proposed mechanism of thrombocytopenia may be immune-mediated peripheral destruction of platelets.
Using Letters Frequency Analysis in Caesar Cipher with Double Columnar Transposition Technique.
Gaurav Shrivastava,Ravindra Sharma,Manorama Chouhan
International Journal of Engineering Sciences & Research Technology , 2013,
Abstract: In this paper we have some modification in Caesar Cipher Technique. We have proposed a method to enhancing the Caesar cipher for more efficient and secure. We use Relative Frequency of Letters in Alphabets. We arrange the sequence of letter according to the frequency in increasing ordered. And then we have made use of a Modified Caesar cipher technique with double Columnar Transposition Technique.
HBV and Indian medical and dental students
Singh Shivaram,Swain Manorama,Kar Indu
Hepatitis B Annual , 2004,
Abstract:
GC-MS Determination of Bioactive components of Polycarpaea corymbosa lams. (Caryophyllaceae)
Sindhu.S,S.Manorama
Hygeia : Journal for Drugs and Medicines , 2013,
Abstract: Plan:The investigation was carried out to determine thepossible chemical components from Polycarpaea corymbosa Lam. root and aerial parts.Methodology: GC-MS was analysed using Agilent (Model 5975C) GasChromatography–Mass Spectrometry.Outcome: GC-MS analysis of methanolic extract of root and aerial part ledto identification of 30 and 24 compounds respectively. The components wereidentified by comparing their retention indices and mass spectra fragmentationpatterns with those stored in the National Institute of Standards andTechnology (NIST) library. The major constituents reported are n-Hexadecanoicacid in methanolic aerial extract and 5-Hydroxymethylfurfural in methanolicroot extract.Keywords:Polycarpaea corymbosa, n-Hexadecanoic acid, 5-Hydroxymethylfurfural.
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