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Search Results: 1 - 10 of 2135 matches for " Makoto Inagami "
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Effect of Difference in Form of Driving Support Agent to Driver’s Acceptability
—Driver Agent for Encouraging Safe Driving Behavior (2)

Takahiro Tanaka, Kazuhiro Fujikake, Takashi Yonekawa, Makoto Inagami, Fumiya Kinoshita, Hirofumi Aoki, Hitoshi Kanamori
Journal of Transportation Technologies (JTTs) , 2018, DOI: 10.4236/jtts.2018.83011
Abstract: In recent years, the number of traffic accidents caused by elderly drivers has increased in Japan. However, a car is an important mode of transportation for the elderly. Therefore, to ensure safe driving, a system that can assist elderly drivers is required. In this study, we propose a driver-agent system that provides support to elderly drivers during and after driving and encourages them to improve their driving. This paper describes the prototype system based on the analysis of the teaching records of a human instructor, and the subjective evaluation of driving support to elderly and non-elderly driver from three different agent forms, a voice, visual, and robot. The result revealed that the robot form is more noticeable, familiar, and acceptable to the elderly and non-elderly than other forms.
Relationship between Senior Drivers’ Cognitive and Physical Functions and Urban Driving Behaviors during Behind-the-Wheel Driving Education Sessions with Driving Instructors  [PDF]
Takashi Yonekawa, Takahiro Tanaka, Hirofumi Aoki, Misako Yamagishi, Yuki Yoshihara, Eijiro Takeuchi, Issey Takahashi, Yoshiki Ninomiya, Hitoshi Kanamori, Tatsuya Suzuki, Makoto Inagami
Journal of Transportation Technologies (JTTs) , 2017, DOI: 10.4236/jtts.2017.72011
Abstract: Recently, traffic accidents caused by elderly drivers have been increasing. It is thought that the reasons of accidents are functions such as decline of eyesight, cognition and physical strength caused by aging. In order to assist safe driving for elderly drivers, it is necessary to sufficiently understand any possible relationship of various senior drivers’ cognition, physical strength and driving behavior. In this paper relationship of elderly driver’s cognition, physical strength and driving behaviors were analyzed using the result of driving instructions on urban road by driving school instructors.
Angiotensin II-mediated vascular smooth muscle cell growth signaling
Inagami, T.;Eguchi, S.;
Brazilian Journal of Medical and Biological Research , 2000, DOI: 10.1590/S0100-879X2000000600002
Abstract: the mechanism by which ang ii stimulates the growth of vascular smooth muscle cells was investigated by measuring the phosphorylation of mitogen-activated protein kinases erk 1 and erk 2. ca2+ ionophore was found to have effects practically analogous to ang ii. we found that the signaling pathway involves the activation of epidermal growth factor receptor (egfr) kinase, activation of the adaptor proteins shc and grb2, and the small g-protein ras. although the mechanism of at1- (or ca2+)-induced activation of egfr is not yet clear, we have found that calcium-dependent protein kinase cak?/pyk2 and c-src are involved in this process. these studies indicate a transactivation mechanism that utilizes egfr as a bridge between a gq-coupled receptor and activation of phosphotyrosine generation.
Angiotensin II-mediated vascular smooth muscle cell growth signaling
Inagami T.,Eguchi S.
Brazilian Journal of Medical and Biological Research , 2000,
Abstract: The mechanism by which Ang II stimulates the growth of vascular smooth muscle cells was investigated by measuring the phosphorylation of mitogen-activated protein kinases ERK 1 and ERK 2. Ca2+ ionophore was found to have effects practically analogous to Ang II. We found that the signaling pathway involves the activation of epidermal growth factor receptor (EGFR) kinase, activation of the adaptor proteins Shc and Grb2, and the small G-protein Ras. Although the mechanism of AT1- (or Ca2+)-induced activation of EGFR is not yet clear, we have found that calcium-dependent protein kinase CAK /PYK2 and c-Src are involved in this process. These studies indicate a transactivation mechanism that utilizes EGFR as a bridge between a Gq-coupled receptor and activation of phosphotyrosine generation.
Spontaneous Bacterial Peritonitis Caused by Listeria monocytogenes Associated with Ascitic Fluid Lymphocytosis: A Case Report and Review of Current Empiric Therapy
Todd Yecies,Sanae Inagami
Case Reports in Hepatology , 2013, DOI: 10.1155/2013/832457
Abstract: Spontaneous bacterial peritonitis (SBP) is a potentially deadly complication of ascites. We describe a case of SBP caused by Listeria monocytogenes in a patient with alcoholic cirrhosis. This was associated with the unusual finding of ascitic fluid lymphocytosis, which previously had only been associated with tuberculoid or malignant ascites. Given increasing rates of cefotaxime-resistant SBP alongside the possibility of Listeriosis, the use of cefotaxime as first-line therapy in SBP should be reevaluated. 1. Introduction Spontaneous bacterial peritonitis is the most common life-threatening infectious complication of cirrhosis, affecting between 10 and 30% of cirrhotic patients hospitalized for ascites [1]. Hospital mortality rates range from 10 to 30%, with the development of progressive renal impairment being the strongest predictor of mortality [2]. SBP is thought to result from increased bacterial translocation across gastrointestinal mucosa combined with diminished host immunity in cirrhotic patients [2]. Enteric gram-negative bacteria are the most common cause of SBP, with E. coli and Klebsiella responsible for more than half of SBP cases [3]; however there is a recent evidence for increasing prevalence of SBP caused by gram-positive cocci [4]. In addition, cases of SBP caused by Candida, anaerobes, and Listeria have been reported [3]. Intravenous cefotaxime is considered standard of care for empiric therapy for SBP after it was demonstrated superior to ampicillin-amikacin [5]. However, recent studies suggest that cefotaxime resistance is increasingly common [4]. Other studies show that empiric amoxicillin-clavulanic acid or ciprofloxacin may be equally effective in select patients [6, 7]. Appropriate selection of empiric antibiotics is essential as absolute mortality rates in patients not covered by the initial antibiotic therapy were 20% higher than in patients with appropriate coverage [8]. Cefotaxime-resistant bacteria that can cause SBP include extended-spectrum beta-lactamase (ESBL) producing gram-negative rods, Enterococci, anaerobes, and Listeria [9]. Fewer than 5 cases of Listeria SBP have been reported in the United States. 2. Case Report This patient is a 62-year-old Caucasian male with a history of alcoholic cirrhosis and ascites who presented with one month of increasing abdominal distention and discomfort. His distention had been worsening since his last paracentesis one-month prior. He was afebrile and otherwise asymptomatic on presentation. Prior to this hospitalization, he had undergone 8 therapeutic large-volume paracenteses over
On Canard Homoclinic of a Liénard Perturbation System  [PDF]
Makoto Hayashi
Applied Mathematics (AM) , 2011, DOI: 10.4236/am.2011.210170
Abstract: The classification on the orbits of some Liénard perturbation system with several parameters, which is relation to the example in [1] or [2], is discussed. The conditions for the parameters in order that the system has a unique limit cycle, homoclinic orbits, canards or the unique equilibrium point is globally asymptotic stable are given. The methods in our previous papers are used for the proofs.
Traffic Dynamics and Congested Phases Derived from an Extended Optimal-Velocity Model  [PDF]
Makoto Watanabe
Engineering (ENG) , 2014, DOI: 10.4236/eng.2014.68048

Dynamics is studied for one-dimensional single-lane traffic flow by means of an extended optimal-velocity model with continuously varied bottleneck strength for nonlinear roads. Two phases exist in this model such as free flow and wide moving jam states in the systems having relatively small values of the bottleneck strength parameter. In addition to the two phases, locally congested phaseappears as the strength becomes prominent. Jam formation occurs with the similar mechanism to the boomerang effect as well as the pinch one in it. Wide scattering of the flow-density relation in fundamental diagram is found in the congested phase.

Employment Protection, Employers’ Hiring Strategies and the Screening Role of Temporary Contracts  [PDF]
Makoto Masui
Modern Economy (ME) , 2016, DOI: 10.4236/me.2016.77080
Abstract: In this paper, we develop a matching model with both permanent and temporary contracts to address situations in which the quality of a match formed by a worker-firm pair is not observable to both workers and firms. The screening and cost-saving aspects of temporary employment contracts are two primary reasons that firms use them, but screening has received little attention in the study of employment protection. We show that increasing dismissal costs decreases job creation and that higher dismissal costs are likely to reduce the hiring threshold for temporary jobs and raise the threshold for permanent jobs. We also examine how changes in dismissal costs affect the average productivity of permanent jobs and discuss the effectiveness of the policy of increasing labour market flexibility by weakening firing restrictions for permanent employment.
On Utilization of K-Means for Determination of q-Parameter for Tsallis-Entropy-Maximized-FCM  [PDF]
Makoto Yasuda
Journal of Software Engineering and Applications (JSEA) , 2017, DOI: 10.4236/jsea.2017.107033
Abstract: In this paper, we consider a fuzzy c-means (FCM) clustering algorithm combined with the deterministic annealing method and the Tsallis entropy maximization. The Tsallis entropy is a q-parameter extension of the Shannon entropy. By maximizing the Tsallis entropy within the framework of FCM, membership functions similar to statistical mechanical distribution functions can be derived. One of the major considerations when using this method is how to determine appropriate q values and the highest annealing temperature, Thigh?, for a given data set. Accordingly, in this paper, a method for determining these values simultaneously without introducing any additional parameters is presented. In our approach, the membership function is approximated by a series of expansion methods and the K-means clustering algorithm is utilized as a preprocessing step to estimate a radius of each data distribution. The results of experiments indicate that the proposed method is effective and both q and Thigh can be determined automatically and algebraically from a given data set.
Guiding of Waves between Absorbing Walls  [PDF]
Dmitrii Kouznetsov, Makoto Morinaga
Journal of Modern Physics (JMP) , 2012, DOI: 10.4236/jmp.2012.37076
Abstract: Guiding of waves between parallel absorbing walls is considered. The principal mode is constructed; its absorption is estimated. The agreement with previous results about reflection of waves from absorbing walls is discussed. Roughly, the effective absorption of the principal mode is proportional the minus third power of the distance between walls, minus 1.5 d power of the wavenumber and minus 0.5 power of the local absorption of the wave in the wall. This estimate is suggested as hint for the design of the atomic waveguides, and also as tool for optimization of attenuation of the amplified spontaneous emission (and suppression of parasitic oscillations) in high power lasers.
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