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Search Results: 1 - 10 of 417702 matches for " Maisa M.;Alberto-Rincon "
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Estudo da intera??o polímero/cartilagem/osso utilizando poli (ácido lático-co-ácido glicólico) e poli (p-dioxanona) em condilo femural de coelhos
Sakata, Maisa M.;Alberto-Rincon, Maria do Carmo;Duek, Eliana A. R.;
Polímeros , 2004, DOI: 10.1590/S0104-14282004000300013
Abstract: bioresorbable devices are alternatives for internal fixation. during the treatment, those devices maintain the fixation, degrade gradually and eliminate the need for a remove surgery, decreasing the treatment cost when compared with metallic devices. the aim of this work was to study the interaction polymer/tissue interaction using pins of plga and pds implanted in new zealand rabbits. the animals were separated in 3 groups which were sacrificed after 3, 6 and 12 weeks after implantation, and the obtained material was submitted to histological analysis. histological analysis with plga implants showed after 3 weeks, the growth of a tissue with mesenchimal characteristics, after 3 weeks, with formation of mature bone aready after 12 weeks. pds implants after 3 weeks showed a bigger invasion of mesenchimal tissue compared to plga and after 12 weeks an advanced degradation occurred, with proliferation of mesenchimal and bone tissue formation. it is concluded that the results are highly positive, with the relevant absence of cells responsible for inflammatory response. analysis showed that the copolymer plga has better ostoinductive properties than pds, showing biocompatibility acceptable for orthopedics application.
Análise histológica da Blenda PLLA/PCL como prótese de menisco
Pinto, M.R.F.;Mariano, E.C.;Alberto-Rincon, M.C.;Duek, E.A.R.;
Matéria (Rio de Janeiro) , 2009, DOI: 10.1590/S1517-70762009000400009
Abstract: the numerous scientific papers applying bioreabsorbable polymers as biomaterial, since 1966, shows the growing interest of researchers in various parts of the world due to its wide range of applications in medicine, such as guided tissue regeneration, controlled release of drugs, support for cells culture, orthopaedic implants, among others. in order to analyze the histologically plla / pcl poly (lactic-acid / poly ( caprolactone) blends composition 70/30 with 3% of plasticizer for application as a meniscal prothesis, a study was performed in vivo in rabbits, which were subjected to total removal of the medial meniscus of the knee, and in one of the knees was implanted in the prosthesis and blend another without implant, served as control. after 8, 16 and 24 weeks, were collected them, along with a prosthesis the tissue around it, the femoral condyle of the prosthesis and the femoral condyle control. the materials were subjected to histological analysis by optical microscopy. the results showed that after 24 weeks, there was the formation of a tissue-type fibrocartilage, indicating that the blend studied presents great potential to be used for application in question, since the material promotes the tissue formation o very similar to the meniscus.
Haste intramedular polimérica bioreabsorvível (PLLA/PHBV) para uso na recupera??o de fraturas ósseas
Ferreira, Betina M. P.;Steffen, Alfredo M.;Cardoso, Túlio P.;Alberto-Rincon, Maria do Carmo;Duek, Eliana A. R.;
Polímeros , 2008, DOI: 10.1590/S0104-14282008000400010
Abstract: the growing interest in medicine with the use of bioreabsorbable polymeric materials has been stimulating researchers from orthopedic area to develop more biological solutions, substituting threads, stems and metallic plates for bioreabsorbable polymers in the treatment of fractures. so, we decided to study implants of the plla/phbv blends (two bioreabsorbable polymers) moulded in a mini-injector. those implants were used for recovery of fractures of rabbit femur and assessed in comparison with the thread of steinmann (stainless steel, commercially used). after euthanasia with 6, 12 and 24 weeks of implantation of the artifacts, the bones were studied with x ray, histological exam and mechanic test, while the polymeric implants were submitted the scanning electron microscopy (sem), mechanic test and modular differential scanning calorimetry (mdsc). the x ray showed good calluses bone with the use of the polymer stem as well as with the metallic control. the histological study showed absence of inflammatory reactions or osteolysis. the mechanical test showed bone consolidation in the two groups. in the mechanical test and in the calorimetry studies, the polymeric stem presented signs of progressive degradation within the studied time. with the data obtained, we can state that the implant plla/phbv demonstrated to be as effective in repairing fractures of rabbit femur as the metallic control.
Characterization of poly (L-co-D,L Lactic Acid) and a study of polymer-tissue interaction in subcutaneous implants in wistar rats
Ciambelli, Giuliano Serafino;Perez, Mariana Ortega;Siqueira, Guilherme Vasconcelos;Candella, Marco Aurélio;Motta, Adriana Cristina;Duarte, Marcia Adriana Tomaz;Alberto-Rincon, Maria do Carmo;Duek, Eliana Aparecida de Rezende;
Materials Research , 2013, DOI: 10.1590/S1516-14392012005000146
Abstract: poly (l-co-d,l lactic acid) (pldla) is an important biomaterial because of its biocompatibility properties that promote cellular regeneration and growth. the aim of this study was to evaluate the polymer-tissue interaction of pldla implants in the dorsal subcutaneous tissue of male wistar rats at various intervals (2, 7, 15, 30, 60 and 90 days) after implantation. physical properties such as the glass transition point (tg), degradation behavior and other mechanical properties were characterized by differential scanning calorimetry (dsc), thermogravimetric analysis (tga), gel permeation chromatography (gpc), scanning electron microscopy (sem) and tension tests. analysis of the degradation of pldla membranes in vitro showed that the polymer became crystalline as a function of the degradation time. mechanical tension tests showed that the polymer behaved like a ductile material: when subjected to constant tension it initially suffered deformation, then elongation and finally ruptured. tga/mev provided evidence of pldla membrane degradation. for histological analysis, samples from each group were processed in xylol/paraffin, except for the 60 - and 90 - day samples. each of the latter samples was divided in two: one half was treated with xylol/paraffin and the other with historesin. light microscopy showed the adhesion of cells to the biomaterial, the formation of a conjunctive capsule around the implant, the presence of epithelioid cells, the formation of foreign body giant cells and angiogenesis. during degradation, the polymer showed a 'lace' - like appearance when processed in xylol/paraffin compared to the formation of "centripetal cracks in the form of glove fingers" when embedded in historesin.
Atmospheric Corrosion
Blanca M. Rosales,Rosa Vera,Oladis Troconis de Rincon,Alejandro Di Sarli,Jaime Alberto Rocha Valenzuela,Johan Tidblad
International Journal of Corrosion , 2012, DOI: 10.1155/2012/174240
A experiência de uma formadora de professores de Química: analisando suas a??es e reflex?es num curso de educa??o continuada
Altarugio, Maisa Helena;Villani, Alberto;
Ciência & Educa??o (Bauru) , 2010, DOI: 10.1590/S1516-73132010000300007
Abstract: this paper is meant to analyze a teacher educator's experience when giving a continuing education course for chemistry teachers, held at a public university in s?o paulo, in 2004. the information here has resulted from the observation of the teacher educator's performance and her reflections on their own ideas, conflicts, anguish and impressions concerning her actions throughout the course. the contrasts between the educator's practice and her reflections are the focus of this study. such contrasts are regarded as a result of the presence of unconscious elements that either favor or hinder practice, and show that reflection and action not always lead to the same direction. we believe individuals should be encouraged to take a more questioning and more reflective attitude, enabling better results in teachers' education as well as more effective performance. data analysis was based on concepts belonging to freud's and lacan's psychoanalytic theories.
The Role of the Educator in the Reflexive Process of Science Teachers
Maisa Helena Altarugio,Alberto Villani
Investiga??es em Ensino de Ciências , 2010,
Abstract: This work aims at discussing practices and discourses of a science teacher educator, of broad experience and of great success, in initial and continuous teaching education. Our hypothesis is that, in addition to the knowledge and techniques, the elements which will sustain the teacher education process are found in the intersubjective relationship construed between the teacher educator and the group of teachers. Considering the unique aspects of the teacher educator in terms of conceiving and facing the educational task, we attempted to highlight the importance of this role, above all, in carrying out the process which focuses on educating and training reflexive teachers in their day-to-day practice. Our analysis applied some elements of the psychoanalysis in S. Freud and J. Lacan, who have revealed to us the potential in exploring aspects of subjective nature of the educational phenomena.
The Histological Effect of Hunger Stress on the Stomach in Male Albino Rats: A Study of Light Microscope
Maisa M. Al-Qudah
Research Journal of Biological Sciences , 2012, DOI: 10.3923/rjbsci.2011.569.574
Abstract: Emotional changes can influence feeding behavior. Feed intake is the cornerstone of animal productivity. The consequences of inadequate intake include inhibited growth, delayed puberty, infertility, reduced milk production and lowered resistance to parasites and disease. In this study, the histological changes observed in male albino rats stomach mucosa which was exposed to hunger were examined. Pieces from stomach were taken in the 1st-5th days following last feeding. These tissue specimens were fixed by using 10% neutral formalin which was compressed. After routine tissue checks, the tissue pieces were sunk into paraffin wax and some blocks were prepared. With the aim to examine histological structures of the pieces taken, they were stained with Hematoxylin and Eosin (H and E). An increase in the number of blood cells taken part in stomach tissue was observed in the first 24 h. At the end of the 3rd day of hunger, necrosis of fundic glands, especially the base of fundus and mild congestion of mucosal blood vessels were observed. A widening in glandular epithelium lumen was seen after 2 days. A tendency to slim was observed in mucosa layer of the surface and glandular lumen during hunger. In the stomach mucosa, structural changes were caused by hunger. It was found that these changes were in direct proportion with hunger duration.
Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival
Tina M. Thornton, Mercedes Rincon
International Journal of Biological Sciences , 2009,
Abstract: The p38 MAPK kinase pathway is activated in response to a wide range of cellular stress stimuli and cytokines. Our understanding of the important functions of p38 MAPK in the process of differentiation and cell death has grown considerably in the recent years and is now relatively established. Here we discuss the role of p38 MAPK in the mediation of cell cycle checkpoints and cell survival, processes that have received less attention. We describe how p38 MAPK regulates both the G2/M as well as a G1/S cell cycle checkpoint in response to cellular stress such as DNA damage. While p38 MAPK has classically been associated with the induction of apoptosis, we discuss that p38 MAPK can also mediate cell survival in specific situations, such as in response to DNA damage. It is important to recognize these less appreciated functions of p38 MAPK when considering the potential use of pharmacological inhibitors of p38 MAPK in therapeutic treatments for disease.
The Stefan problem with moving boundary
M. A. Rincon,A. Scardua
Boletim da Sociedade Paranaense de Matemática , 2008,
Abstract: A mathematical model of the linear thermodynamic equations with moving ends, based on the Stefan Problem is considered. In this work, we are interested in obtaining existence, uniqueness and regularity using the Faedo-Galerkin method. For numerical solutions, we shall employ the finite element method together with the Crank-Nicolson method. A numerical experiment is presented to show the moving boundary for the problem.
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