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Search Results: 1 - 10 of 460 matches for " MG;Cogo "
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Bothrops jararacussu venom-induced neuromuscular blockade inhibited by Casearia gossypiosperma Briquet hydroalcoholic extract
Camargo, TM;Nazato, VS;Silva, MG;Cogo, JC;Groppo, FC;Oshima-Franco, Y;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2010, DOI: 10.1590/S1678-91992010000300009
Abstract: the hydroalcoholic extract of casearia gossypiosperma briquet (flacourtiaceae) was standardized for the first time through quality control procedures including pharmacognostic methods, fingerprint chromatograms, defined amounts of marker substances and physicochemical characteristics. the pharmacological activity of c. gossypiosperma (cg) hydroalcoholic extract was assayed by a traditional in vitro test, which involved irreversible neuromuscular blockade induced by bothrops jararacussu (bjssu) venom (60 μg/ml) in mouse phrenic nerve-diaphragm preparations. bjssu venom blocked muscle activity for 26 (± 2.0) minutes (n = 6). cg extract (0.1 mg/ml) induced changes on the baseline muscle activity without impairing the muscle function and inhibited 87.6% (± 1.8) (n = 6) of the bjssu venom-induced blockade. both flavonoids (0.624 g%) and polyphenols (4.63 g%) from the extract were spectrophotometrically quantified. therefore, the present study confirms the antibothropic activity of cg extract, supporting the ethnomedical use of casearia sp. in the treatment of snakebite victims.
The lung at high altitude
Annalisa Cogo
Multidisciplinary Respiratory Medicine , 2011, DOI: 10.1186/2049-6958-6-1-14
Abstract: A new classification of altitude levels based on the effects on performance and well-being has been recently proposed [1]: the decrease in partial pressure of oxygen reduces maximal oxygen uptake and impairs "aerobic" performance by reducing maximal aerobic power. Submaximal exercise performance is also impaired at altitude. When the acclimatization is not adequate, hypoxia triggers maladaptive responses that lead to various forms of high altitude illness or acute mountain sickness (AMS), characterized by headache plus gastrointestinal symptoms (anorexia, nausea) and sleep disturbances. AMS is present in 10-30% of subjects at altitudes between 2500 and 3000 m a.s.l. and is usually due to a fast ascent. It is well defined by the short phrase: "Too fast, too high". Less frequent, but much more serious, consequences are high-altitude cerebral edema (HACE), and high-altitude pulmonary edema (HAPE).The lung response to acute altitude exposure is mainly hyperventilation which, together with elevated heart rate, aims at achieving an adequate supply of oxygen to the tissues. At rest, ventilation increases by firstly increasing the tidal volume, at least up to 3500 m. Above this altitude, also the breathing rate significantly increases. Besides the compensatory response, other mechanisms affect lung physiology during hypoxic exposure: the increase of pulmonary artery pressure and endothelial permeability which can explain the extravascular lung fluid accumulation described in many papers [2]. It must be underlined that the interstitial fluid accumulation which affects a large part of climbers at high altitude should be considered a para-physiological mechanism and does not predict subsequent pulmonary edema [3].The role of the lung in the acute exposure to altitude was first described by Angelo Mosso, physiologist at the University of Torino, at the end of the 19th century. He very well pointed out the changes in ventilation and the reduction of lung volumes consistent with
Libraries Demonstrate Low Adherence to Virtual Reference Service Guidelines. A Review of: Shachaf, Pnina, and Sarah M. Horowitz. “Virtual Reference Service Evaluation: Adherence to RUSA Behavioral Guidelines and IFLA Digital Reference Guidelines.” Library & Information Science Research 30.2 (2008): 122-37.
Elise Cogo
Evidence Based Library and Information Practice , 2009,
Abstract: Objectives – This study evaluates the level to which virtual (asynchronous e-mail) reference services adhere to professional guidelines. Specifically, it addresses the following research questions: 1) To what extent do virtual reference services adhere to the American Library Association (ALA) Reference and User Services Association (RUSA) and the International Federation of Library Associations (IFLA) guidelines? 2) How does the level of adherence to RUSA or IFLA guidelines vary based on request type, user name, and institution? 3) Is there a correlation between outcome measures of reference transactions (accuracy, completeness, and satisfaction) and the level of adherence to RUSA or IFLA guidelines? Design – Unobtrusive evaluation of researcher-generated queries. Setting – Fifty-four academic libraries in North America. Subjects – A total of 324 queries were sent to the 54 libraries, with each library receiving six different types of requests from six different user names. Methods – Researchers developed two coding schemes for the guidelines (34 codes and 12 attributes for the RUSA guidelines and 33 codes and 10 attributes for the IFLA guidelines). Each of the six user names used represented an ethnic and/or religious group identity: Mary Anderson (Caucasian, Christian), Moshe Cohen (Caucasian, Jewish), Ahmed Ibrahim (Arab), Latoya Johnson (African American), Rosa Manuz (Hispanic), and Chang Su (Asian). The six request types were designed so that three would be answered (questions 1-3) and three would be out of scope and not answered (questions 4-6). The following queries were sent, individualized for each institution: 1) Dissertation query; 2) Sports team query; 3) Population query; 4) Subject query; 5) Article query; 6) Request for a PDF copy. The 324 queries were uploaded into NVivo 2 software, and all e-mail transactions were coded and analyzed. Main Results – Analysis of the 324 transactions from 54 libraries showed the following results:1) Low levels of adherence to both sets of guidelines;2) Varied levels of adherence based on request types and user names on both sets of guidelines;3) Variation in institutional rank according to different sets of guidelines;4) No correlation between user satisfaction and adherence to either set of guidelines. Conclusion – This study suggests that higher levels of virtual reference service effectiveness could be achieved by automatically integrating some less observed behaviours (e.g., thank you notes) into replies sent to users and by increasing librarians’ awareness of professional guidelines through training
O Outro migrante: das estratégias de midiatiza o das migra es contemporaneas na mídia impressa brasileira
Denise Cogo
Ciberlegenda , 2011,
Abstract: O artigo analisa os processos de produ o de sentido sobre os fen menos migratórios contemporaneos na mídia impressa brasileira. A partir das inter-rela es entre processos de midiatiza o, experiência migratória e interculturalidade, é desenvolvido um mapeamento inicial e uma análise discursiva sobre as estratégias de midiatiza o das migra es e das falas imigrantes em uma amostra de jornais representativos das cinco regi es brasileiras e uma das principais revistas de circula o nacional.
The safe spinal anaesthetic: Spinal anaesthesia is not without its complications and should only be performed for the correct indications
MG Senekal
Continuing Medical Education , 2012,
Evaluation of Anthropometric Status of Hausas of Northern Nigeria
MG Taura
Bayero Journal of Pure and Applied Sciences , 2011,
Abstract: Anthropometry is a branch of anthropology that deals with the measurements of various parts of human body which are expected to grow predictably and proportionately. The aim of this work was to study some of the anthropometric parameters of the Hausa people residing in Kano, northwestern Nigeria. Anthropometric parameters measured and recorded in this study were height, weight, body mass index and blood pressure. The measurements were made according to the standard procedures. Sample size of 1113 subjects comprising of 599 (53.8%) males and 504 (46.2%) females were used for the study. The age range of the subjects was 18 to 60 years with mean age of 23.2 years. Instruments used included weighing machine, stadiometer, and blood pressure apparatus. The results showed that all values were higher in males than females except for body mass index which was higher in female subjects. Bivariate analysis showed a positive correlation between the parameters except for height and body mass index where a negative correlation was observed. The values of the anthropometric parameters in this study were similar to those of other Nigerian ethnic groups and tribes. The values also correlate with the findings from other countries. It is concluded from the findings of this study that the anthropometric parameters and blood pressure of the Hausas of northern Nigeria are within acceptable reference range.
Influence of Socio-Economic Variables on Dry Season Fluted Pumpkin Production in Njikoka Local Government Area of Anambra State, Nigeria
MG Nenna
Journal of Agricultural Extension , 2011,
Abstract: The paper examined the influence of Socio economic variables on dry season fluted pumpkin production in Njikoka Local Government Area of Anambra State, Nigeria. A multi-stage sampling technique was used to select the respondents for the study. Primary data was collected by means of structured questionnaire and 3- point liket scale. Nonparametric and parametric statistical tools including frequency distribution, percentages, means, mean ranking and multiple regression analysis were deployed for the data analysis. Majority (45%) of the farmers were aged 51-60 years and 95% were females. The result revealed that 47.50% of the respondents earned N76, 000. and above, indicating poverty level slightly above the benchmark of one U.S dollar per day. The multiple regression analysis showed that income of the farmers was significantly influenced by educational level, fertilizer application and access to credit at 5% level of significance. The paper revealed the constraints of the farmers to include insufficient land, lack of credit, high cost of labour, high cost of farm inputs among others. The result also showed a dearth in extension delivery system, especially in the dissemination of useful and technical information and procurement of improved yield increasing agricultural technologies to farmers. This suggests the need for intensified efforts of extension in the areas of seminars, workshops, meetings, conferences etc for farmers. Finally, government should subsidize improved agricultural inputs to enable the farmers compete favourably with the recent challenges in agricultural production.
Assessment of Services Provided By Village Alive Women Association to Rural Women in Ifelodun Local Government Area of Kwara State, Nigeria
MG Olujide
Journal of Agriculture and Social Research (JASR) , 2011,
Abstract: Recent changes in the social and economic conditions of many nations of the world have led to the on-going special attention being focused on the role of rural women in development. As a result of these strategies, the research was initiated to study the analysis of services provided by Village Alive Women Association (VAWA) for the rural women in Ifelodun Local Government Area of Kwara State. This study focus on demographic characteristics of the beneficiaries, services provided by VAWA, attitude of rural women towards the VAWA services, level of participation of rural women, constraints facing the rural women and the benefit derived by rural women from the VAWA services. Information required for this study was obtained through the use of interview schedule which include open and close ended questions. Four villages were selected one of which 102 respondents (10% of the whole population) were randomly chosen to form the sample for the study, the result indicated that most of the respondents are young adult women between the ages of 18 – 30 years. Most of them had no formal education. The findings using Chi-square and Correlation analysis showed that stenographic characteristics of the respondents are significant with the services of VAWA to the rural women. It was confirmed that the respondents have a favourable attitude, level of participation, constraints and benefit derived towards VAWA services and they are more willing to continue with the activities of VAWA. In view of the above, the study recommended that money and other necessary technologies should be made available to the hardworking Rural women of Nigeria by different NGOs and Voluntary organizations so that they can increase their productivity those government organs or agencies (ADP, MANR, NCAM) set up to ameliorate the hardship of rural women should realize their potentialities ad come to their aid with incentives. Further research shall be conducted to look at the analysis of each of the VAWA services and the impact of governmental and non-governmental organizations assistance to income generating activities of women in the rural areas.
Hierarchically nanostructured hydroxyapatite: hydrothermal synthesis, morphology control, growth mechanism, and biological activity
International Journal of Nanomedicine , 2012, DOI: http://dx.doi.org/10.2147/IJN.S29884
Abstract: archically nanostructured hydroxyapatite: hydrothermal synthesis, morphology control, growth mechanism, and biological activity Original Research (3600) Total Article Views Authors: Ma MG Published Date April 2012 Volume 2012:7 Pages 1781 - 1791 DOI: http://dx.doi.org/10.2147/IJN.S29884 Received: 12 January 2012 Accepted: 02 February 2012 Published: 03 April 2012 Ming-Guo Ma Institute of Biomass Chemistry and Technology, College of Materials Science and Technology, Beijing Forestry University, Beijing, People's Republic of China Abstract: Hierarchically nanosized hydroxyapatite (HA) with flower-like structure assembled from nanosheets consisting of nanorod building blocks was successfully synthesized by using CaCl2, NaH2PO4, and potassium sodium tartrate via a hydrothermal method at 200°C for 24 hours. The effects of heating time and heating temperature on the products were investigated. As a chelating ligand and template molecule, the potassium sodium tartrate plays a key role in the formation of hierarchically nanostructured HA. On the basis of experimental results, a possible mechanism based on soft-template and self-assembly was proposed for the formation and growth of the hierarchically nanostructured HA. Cytotoxicity experiments indicated that the hierarchically nanostructured HA had good biocompatibility. It was shown by in-vitro experiments that mesenchymal stem cells could attach to the hierarchically nanostructured HA after being cultured for 48 hours. Objective: The purpose of this study was to develop facile and effective methods for the synthesis of novel hydroxyapatite (HA) with hierarchical nanostructures assembled from independent and discrete nanobuilding blocks. Methods: A simple hydrothermal approach was applied to synthesize HA by using CaCl2, NaH2PO4, and potassium sodium tartrate at 200°C for 24 hours. The cell cytotoxicity of the hierarchically nanostructured HA was tested by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Results: HA displayed the flower-like structure assembled from nanosheets consisting of nanorod building blocks. The potassium sodium tartrate was used as a chelating ligand, inducing the formation and self-assembly of HA nanorods. The heating time and heating temperature influenced the aggregation and morphology of HA. The cell viability did not decrease with the increasing concentration of hierarchically nanostructured HA added. Conclusion: A novel, simple and reliable hydrothermal route had been developed for the synthesis of hierarchically nanosized HA with flower-like structure assembled from nanosheets consisting of nanorod building blocks. The HA with the hierarchical nanostructure was formed via a soft-template assisted self-assembly mechanism. The hierarchically nanostructured HA has a good biocompatibility and essentially no in-vitro cytotoxicity.
Exploring safety in township secondary schools in the Free State province
MG Masitsa
South African Journal of Education , 2011,
Abstract: Research overwhelmingly suggests that effective teaching and learning can occur only in a safe and secure school environment. However, despite the plethora of laws and acts protecting teachers and learners in South African schools, scores of them are still unsafe. This study examines the safety of teachers and learners in township secondary schools in the Free State province, South Africa. The sample of study consisted of 396 teachers who were randomly selected from 44 township secondary schools across the province. The sample completed a questionnaire based on the safety of teachers and learners in their schools. Prior to completion, the questionnaire was tested for reliability using the Cronbach alpha coefficient and it was found to have a reliability score of .885, indicating an acceptable reliability coefficient. The questionnaire was computer analysed using the Statistical Package for Social Sciences Primer Version 12. The results of the analysis revealed that both teachers and learners are not safe in their schools, either during or after school hours. The causes of a lack of safety in these schools reside within and without the schools, implying that learners are sometimes the culprits. The study concludes with recommendations on addressing the problem.
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