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Search Results: 1 - 10 of 2201 matches for " MEASLES VACCINE "
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Relationship between Self-Reported Vaccination History and Measles and Rubella Antibody Titers in Medical and Nursing Students  [PDF]
Masanori Ogawa, Ryusuke Ae, Teppei Sasahara
Advances in Infectious Diseases (AID) , 2017, DOI: 10.4236/aid.2017.72004
Abstract: In hospitals, infection control for measles and rubella is important. Medical and nursing students as well as healthcare workers must have immunity against these diseases. Many countries have adopted requirements for healthcare workers’ documented vaccination history or laboratory tests as evidence of their immunity. Evaluating a written vaccination history is difficult in many cases. Therefore, we compared measles and rubella antibody titers with self-reported vaccination history and we evaluated the association between the history and measles and rubella antibody titers, using the medical and nursing students’ data. We analyzed 564 data for measles and 558 data for rubella. Vaccination history was requested to be completed as accurately as possible. Students with one or more measles or rubella vaccinations had high positive ratios of titer, and the ratio was significantly higher than that of the students without vaccinations. The positive ratio between the two-dose and one-dose vaccination groups was not significantly different for measles or rubella (measles: p = 0.534, rubella: p = 0.452). Although it should be requested that the history is complete by using other resources, such as referring to maternity passbooks or proof of vaccination, self-reported history may be useful to confirm immunity, even if there is a possibility that the history is not accurate.
Clinical Trial of Measles and Rubella Combined Vaccine Produced by POLYVAC in Vietnam  [PDF]
Nguyen Dang Hien, Nguyen Thuy Huong, Ngo Thu Huong, Pham Thi Phuong Thao, Dinh Hong Duong, Nguyen Xuan Dong, Tomio Lee, Takashi Ito, Tetsuo Nakayama
Open Journal of Pediatrics (OJPed) , 2018, DOI: 10.4236/ojped.2018.82020
Abstract: A clinical trial of measles and rubella combined vaccine (MR: MRVAC) produced by POLYVAC was conducted in Vietnam in 2016. A total of 756 subjects were enrolled, and 504 were allocated to MRVAC and 252 to control MR vaccine groups. Paired sera were obtained in 733, and the number of subjects was 403 aged 1 - 2 years, 164 aged 2 - 18 years, and 166 aged 18 - 45 years. Antibodies against measles and rubella viruses were evaluated by EIA. Most subjects had been immunized with a single dose of Expanded Programme on Immunization (EPI) measles vaccine at 9 months of age. Only 41 of 403 subjects aged 1 - 2 years were negative for measles antibody before vaccination, and all became seroconverted. A serological response of more than a 2-fold increase against measles was noted in 214 (47%, 95% CI; 42.4%
Perfil epidemiológico do sarampo no Estado de Santa Catarina, Brasil, de 1996 a 2000
Faversani, Maria Cristina de Sousa Santos;Kupek, Emil;Westrupp, Maria Helena Bittencourt;
Cadernos de Saúde Pública , 2005, DOI: 10.1590/S0102-311X2005000200020
Abstract: this ecological study, based on an analysis of secondary data from epidemiological surveillance and using the municipality (county) as the unit of analysis, showed that measles vaccine coverage was lower than necessary for eradication (95%) and control (90%) in many municipalities in the state of santa catarina, brazil, both before and during the last epidemic in 1997, particularly regarding the second dose of the vaccine, applied as a component of the mmr vaccine, scheduled at 15 months of age. low vaccine coverage was associated with higher measles incidence. however, during the 1997 epidemic small-scale measles outbreaks were recorded even in municipalities with first-dose coverage of 95% or higher, particularly among those which also had low second-dose coverage for mmr. approximately 80% of all measles cases during 1996-2000 occurred among schoolchildren and young adults. measles virus circulation in the municipality in the previous year and population density increased the risk of measles. two imported cases of measles in santa catarina in 2004 illustrate that it would be premature to describe the current situation as one of eradication.
Measles vaccination: influence of age on its efficacy
Lopes, Marta Heloísa;Mendon?a, Jo?o Silva de;Pannuti, Cláudio Sérgio;Albrecht, Paul;Biancalana, Maria Lúcia Neves;Mantese, Orlando César;Correa, José Fábio;Amato Neto, Vicente;
Revista do Instituto de Medicina Tropical de S?o Paulo , 1989, DOI: 10.1590/S0036-46651989000500005
Abstract: the authors compare the serologic efficacy and the clinical protection afforded by three different measles vaccination schemes in adequately nourished children in s?o paulo city, brazil. two hundred forty two children were divided into three groups. group a, comprising 117 children who had received the vaccine before 12 months of age and a second dose at 12 months of age or more. group b, comprising 46 children who had received only one dose, before 12 months of age. group c, comprising 79 children who had received only one dose, at 12 months of age or more. the geometric mean titer of antibodies in group a was 790.1; in group b, 251.1; and in group c, 550.3. there was no statistically significant difference between groups a and c. the exposure to the measles virus was probably similar in all groups, and the children in groups a and c had similar chances of acquiring the disease after vaccination whereas in group b the chances were higher when compared to the other two groups. the results obtained in this study favor the use, in developing countries, of a vaccination program against measles that includes an early first dose at eight months of age and revaccination after 12 months of age.
Soroprevalência de anticorpos contra o sarampo de uma determinada popula??o infantil de Botucatu, SP
Godoy, Ilda de;Meira, Domingos Alves;
Revista da Sociedade Brasileira de Medicina Tropical , 2000, DOI: 10.1590/S0037-86822000000300004
Abstract: a study of the seroprevalence of measles antibodies was conducted in a population of children residing in botucatu, sp, in order to asses their immunological status whether induced by natural infection or by vaccination. a total of 101 children were studied, all of which had been vaccinated against measles. the laboratory tests used to determine the presence of antibodies in the collected blood samples were hemagglutination inhibition (hi) and immunoenzymatic assay (elisa). hi results showed that 92.1% of the samples presented antibodies against measles. samples with titers <1:4 when studied by hi were retested by elisa in the same laboratory and only two continued to be negative for measles antibodies. thus, measles antibodies were present in 98% of the serum samples from the children studied.
Measles, Mumps, and Rubella Vaccine (MMR)
Gulten Secmeer,Sinan Oguz
Cocuk Enfeksiyon Dergisi , 2008,
Abstract: Measles, mumps and rubella are important infectious diseases in childhood which can cause mortality and morbidity. Protection by vaccine is possible, so the World Health Organization proposes vaccination. Combination of vaccines are used for routine immunization because they are much easier to use and cause no increase in side effects and no decrease in immunity. These diseases and complications were decreased after vaccination programes in our country as in other developed countries.
Sarampo: inquérito sobre antecedentes vacinal e de doen?a em crian?as de 0 a 14 anos, atendidas nos Centros de Saúde Estaduais do Município de S?o Paulo, 1976
Barbosa,Victório; Iversson,Lygia Busch; Aquino,Alba Chiara de;
Revista de Saúde Pública , 1977, DOI: 10.1590/S0034-89101977000400009
Abstract: a survey was undertaken in july 1976, envolving 3096 children, with ages ranging from 0 to 14 years, attending the city of s?o paulo state public health centres, brazil, with the aim of identifying the population still able to contract measles either because they had not the illness or because they had not been vaccinated. the survey also aimed at getting other local informations important to the epidemiological surveillance of measles.
Epidemic Outbreaks in Plovdiv Region (Bulgaria) of Vaccine-Preventable Diseases: Measles, Mumps, Hepatitis A  [PDF]
Nikolay Todorov Vatev, Mariyana Vartigova Stoycheva, Andrei Ivanov Petrov, Rayna Dimitrova Velcheva
World Journal of Vaccines (WJV) , 2012, DOI: 10.4236/wjv.2012.23023
Abstract: Aim: To analyze the reasons for epidemic outbreaks of measles, mumps and viral hepatitis A and to propose measures to prevent them in future. Materials and methods: Тhe incidence of measles, mumps and hepatitis A in Plovdiv region was studied for the period 2006-2010. An analysis of the age structure of the patients was made, while taking into account the time for routine immunization performed against measles and mumps (first and second dose). Results: In 2006-2009 single cases of measles were found occasionally, but in 2010 they were 2787 (incidence 395/100,000). Most of them (51%) were for ages 13 months-12years, 27%-0-13 months and 11%-13 to 18 years. The incidence of mumps for 2006-2010 varied widely, and has increased significantly in 2007 (130/100,000) and 2008 (169/100,000). The majority of patients (over 34%) during the epidemics were aged 13 months-12years, and over 26% of them-13-19 years. For the period 2006-2010 the incidence of hepatitis A ranged from 2.98/100, 000 (2009) to 426/100,000 (2006). Over 50% of the cases involved children aged up to 9 years. For the three diseases over 80% of patients were individuals of Roma origin. Conclusions: 1. Epidemic spread of measles in 2010 was mainly due to shortcomings in the routine immunization carried as a prevention of the disease. 2. There are two reasons for the outbreak of mumps: А) Failure to administer the second vaccine dose at 12 years in Bulgaria until 2001. B) Shortcomings in routinely performed immunization. 3. The extremely high incidence of hepatitis A in 2006 (and in the rest of the years) is due to the lack of routine immunization. 4. Essential for the outbreaks in all three diseases are the poor hygienic living conditions, the low social status and the lack of health promotion of the population at risk 5. To prevent future outbreaks of the diseases hereby in question, we suggest it is appropriate: А) To introduce compulsory immunization against hepatitis A; B) To carry out periodic catch-up vaccination campaigns against measles and mumps.
El sarampión: una realidad y un desafío
Carballo López,María Teresa; García Torres,Milady; Galindo Sardi?a,Miguel ángel;
Revista Cubana de Higiene y Epidemiolog?-a , 1998,
Abstract: the historical antecedents of measles, and the fundamental aspects of the virus are presented in this paper. some of its characteristics such as the causal agent and its diverse complications, as well as the techniques used for the diagnosis and the development of measles vaccines since their appearance up to now are also approached. reference is also made to the epidemiological aspects and to the situation of this disease in cuba.
From control to elimination: the research agenda for measles
Robin Biellik
Pan African Medical Journal , 2010,
Abstract: Five out of 6 WHO regions have set time-limited goals to move from regional measles mortality reduction to the regional elimination of indigenous transmission. Despite the abundance of research, there are a number of unanswered questions as we move towards a goal of measles elimination, many of which will be critical to achieving the elimination goal. We present here a list of research priorities from a programmatic and operational perspective
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