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Search Results: 1 - 10 of 537999 matches for " M.G.;Carvalho "
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Inibi??o e inativa??o in vitro de diferentes métodos de extra??o de Ocimum gratissimum L. ("alfavac?o", "alfavaca", "alfavaca-cravo") - Labiatae (Lamiaceae), frente a bactérias de interesse em alimentos
Passos, M.G.;Carvalho, H.;Wiest, J.M.;
Revista Brasileira de Plantas Medicinais , 2009, DOI: 10.1590/S1516-05722009000100012
Abstract: dilution tests in multiple tube system were used to evaluate the intensity of bacterial inhibition activity (iinib/bacteriostasis) and bacterial inactivation activity (iinab/bactericide) of conserver solutions containing ethanolic (alcoholature/in natura plant, hidroalcoholature/dry plant) and aqueous (decoctions/in natura or dry plant) extracts of ocimum gratissimum l. ("alfavac?o", "alfavaca", "alfavaca-cravo") - labiatae - (lamiaceae) on standardized inocula of salmonella enteritidis (atcc 11076), escherichia coli (atcc 11229) and staphylococcus aureus (atcc 25923). all the different extraction methods presented selective inhibition and/or inactivation on the bacterial inocula. the alcoholic extract had the highest antibacterial activity (inhibition/inactivation) against the three agents. salmonella enteritidis was the most sensitive to the antibacterial activity in all conserver solutions. staphylococcus aureus showed the lowest sensitivity to decoctions, whereas escherichia coli was the least sensitive to the hydroalcoholic extraction.
Poor response to tuberculosis treatment with regimens without rifampicin in immunosuppressed AIDS patients
O'Donnel M.M.,Souza Carvalho S.,Gadelha A.J.,Morgado M.G.
Brazilian Journal of Infectious Diseases , 2002,
Abstract: A prospective study was conducted on 79 advanced immunosuppressed AIDS patients from 1997 to 1999, during which nine cases of tuberculosis (TB) were diagnosed. The main clinical and laboratory characteristics and the response to TB treatment were reviewed. The clinical manifestations of TB were: pulmonary (six cases), extrapulmonary (two cases) and disseminated (one case). These patients were being treated with highly active antiretroviral treatment (HAART) and were not responding. In three cases an optional regimen without rifampicin (RMP) was indicated to maintain HAART during TB treatment. A clinical response to TB treatment (disappearance of fever) was observed in 6/9 patients during a mean of 73 days (SD = 96). The three unresponsive patients were those treated without RMP. A switch to TB regimens containing RMP was proposed and successful. In our study, though it was limited by a small sample size, the response to TB regimens without rifampin was poor in immunossupressed patients failing HAART.
Influência da época de colheita e do genótipo de cana-de-a?úcar sobre a infesta??o de Mahanarva fimbriolata (Stal) (Hemiptera: Cercopidae)
Dinardo-Miranda, Leila L.;Ferreira, José M.G.;Carvalho, Paulo A.M.;
Neotropical Entomology , 2001, DOI: 10.1590/S1519-566X2001000100021
Abstract: the objective of this work was to study the effect of harvest period and sugarcane genotypes on mahanarva fimbriolata (stal) infestation. under field conditions, 18 genotypes were harvested in three periods: may, august and october. the highest root froghoppers populations were obtained in the field were sugarcane was harvested in may, probably because, during summer, when the root froghopper attack is more intensive, the plants were more grown. in consequence, the soil was more shaded and humid, favouring the root froghopper development. the genotypes iac83-2396, sp80-1842 and rb825336 were severely attacked and were preferred by the pest. the cultivars rb72454, rb835486 e iac86-2210 also presented high populational levels. iac82-3092, iac87-3197 and po86-1107 presented the smallest pest infestations.
Preliminary risk analysis applied to the handling of health-care waste
Carvalho, S.M.L.;Silva, M.G.C.;
Brazilian Journal of Chemical Engineering , 2002, DOI: 10.1590/S0104-66322002000400004
Abstract: between 75% and 90% of the waste produced by health-care providers no risk or is "general" health-care waste, comparable to domestic waste. the remaining 10-25% of health-care waste is regarded as hazardous due to one or more of the following characteristics: it may contain infectious agents, sharps, toxic or hazardous chemicals or it may be radioactive. infectious health-care waste, particularly sharps, has been responsible for most of the accidents reported in the literature. in this work the preliminary risks analysis (pra) technique was used to evaluate practices in the handling of infectious health-care waste. currently the pra technique is being used to identify and to evaluate the potential for hazard of the activities, products, and services from facilities and industries. the system studied was a health-care establishment which has handling practices for infectious waste. thirty-six procedures related to segregation, containment, internal collection, and storage operation were analyzed. the severity of the consequences of the failure (risk) that can occur from careless management of infectious health-care waste was classified into four categories: negligible, marginal, critical, and catastrophic. the results obtained in this study showed that events with critics consequences, about 80%, may occur during the implementation of the containment operation, suggesting the need to prioritize this operation. as a result of the methodology applied in this work, a flowchart the risk series was also obtained. in the flowchart the events that can occur as a consequence of a improper handling of infectious health-care waste, which can cause critical risks such as injuries from sharps and contamination (infection) from pathogenic microorganisms, are shown.
Preliminary risk analysis applied to the handling of health-care waste
Carvalho S.M.L.,Silva M.G.C.
Brazilian Journal of Chemical Engineering , 2002,
Abstract: Between 75% and 90% of the waste produced by health-care providers no risk or is "general" health-care waste, comparable to domestic waste. The remaining 10-25% of health-care waste is regarded as hazardous due to one or more of the following characteristics: it may contain infectious agents, sharps, toxic or hazardous chemicals or it may be radioactive. Infectious health-care waste, particularly sharps, has been responsible for most of the accidents reported in the literature. In this work the preliminary risks analysis (PRA) technique was used to evaluate practices in the handling of infectious health-care waste. Currently the PRA technique is being used to identify and to evaluate the potential for hazard of the activities, products, and services from facilities and industries. The system studied was a health-care establishment which has handling practices for infectious waste. Thirty-six procedures related to segregation, containment, internal collection, and storage operation were analyzed. The severity of the consequences of the failure (risk) that can occur from careless management of infectious health-care waste was classified into four categories: negligible, marginal, critical, and catastrophic. The results obtained in this study showed that events with critics consequences, about 80%, may occur during the implementation of the containment operation, suggesting the need to prioritize this operation. As a result of the methodology applied in this work, a flowchart the risk series was also obtained. In the flowchart the events that can occur as a consequence of a improper handling of infectious health-care waste, which can cause critical risks such as injuries from sharps and contamination (infection) from pathogenic microorganisms, are shown.
DNA topoisomerase inhibitors: biflavonoids from Ouratea species
Grynberg N.F.,Carvalho M.G.,Velandia J.R.,Oliveira M.C.
Brazilian Journal of Medical and Biological Research , 2002,
Abstract: Topoisomerase inhibitors are agents with anticancer activity. 7"-O-Methyl-agathisflavone (I) and amentoflavone (II) are biflavonoids and were isolated from the Brazilian plants Ouratea hexasperma and O. semiserrata, respectively. These biflavonoids and the acetyl derivative of II (IIa) are inhibitors of human DNA topoisomerases I at 200 μM, as demonstrated by the relaxation assay of supercoiled DNA, and only agathisflavone (I) at 200 μM also inhibited DNA topoisomerases II-alpha, as observed by decatenation and relaxation assays. The biflavonoids showed concentration-dependent growth inhibitory activities on Ehrlich carcinoma cells in 45-h culture, assayed by a tetrazolium method, with IC50 = 24 ± 1.4 μM for I, 26 ± 1.1 μM for II and 10 ± 0.7 μM for IIa. These biflavonoids were assayed against human K562 leukemia cells in 45-h culture, but only I showed 42% growth inhibitory activity at 90 μM. Our results suggest that biflavonoids are targets for DNA topoisomerases and their cytotoxicity is dependent on tumor cell type.
Magneto Hydrodynamic Orthogonal Stagnation Point Flow of a Power-Law Fluid Toward a Stretching Surface  [PDF]
Manisha Patel, M.G Timol
American Journal of Computational Mathematics (AJCM) , 2011, DOI: 10.4236/ajcm.2011.12013
Abstract: Steady two dimensional MHD stagnation point flow of a power law fluid over a stretching surface is investigated when the surface is stretched in its own plane with a velocity proportional to the distance from the stagnation point. The fluid impinges on the surface is considered orthogonally. Numerical and analytical solutions are obtained for different cases.
Prevalência de rotavírus do grupo A em fezes diarréicas de bezerros de corte em sistema semi-intensivo de produ o
Buzinaro M.G.,Mistieri M.L.A.,Carvalho A.A.B.,Samara S.I.
Arquivo Brasileiro de Medicina Veterinária e Zootecnia , 2003,
Abstract: Determinou-se a prevalência de rotavírus durante surto de diarréia em bezerros de um rebanho de corte, criado em regime semi-intensivo de produ o. Analisaram-se, por meio de técnicas de eletroforese em gel de poliacrilamida (EGPA) e ensaio imunoenzimático (kit EIARA - Fiocruz), 69 amostras de fezes de bezerros, entre 30 e 60 dias de idade, colhidas em três esta es de pari o consecutivas (agosto a novembro/1999, janeiro a abril e agosto a novembro/2000). Pelo EIARA foram detectadas 63,8% (44/69) de amostras positivas. Na primeira esta o de pari o foi detectado rotavírus em 82,4% (14/17) dos bezerros que apresentaram quadro clínico de diarréia. No ano de 2000 a presen a de rotavírus foi detectada em 41,7% (5/12) e 62,5% (25/40) do total de amostras examinadas. A análise do perfil eletroforético do genoma indicou grande diversidade, com quatro eletroferótipos distintos, todos com perfil longo, característico de rotavírus do grupo A.
Hemodynamic and hormonal actions of adrenomedullin
Nicholls, M.G.;
Brazilian Journal of Medical and Biological Research , 2004, DOI: 10.1590/S0100-879X2004000800016
Abstract: adrenomedullin, a 52-amino acid residue peptide, has numerous biological actions which are of potential importance to cardiovascular homeostasis, growth and development of cardiovascular tissues and bone, prevention of infection, and regulation of body fluid and electrolyte balance. studies in man using intravenous infusion of the peptide have demonstrated that, at plasma levels detected after myocardial infarction or in heart failure, adrenomedullin reduces arterial pressure, increases heart rate and cardiac output, and activates the sympathetic and renin-angiotensin systems but suppresses aldosterone. the thresholds for these responses differ, being lower under some experimental circumstances for arterial pressure than for the other biological effects. adrenomedullin administration inhibits the pressor and aldosterone-stimulating action of angiotensin ii in man. by contrast, the pressor effect of norepinephrine is little altered by concomitant adrenomedullin administration. although in the absence of a safe, specific antagonist of the actions of endogenous adrenomedullin it is difficult to be certain about the physiological and pathophysiological importance of this peptide in man, current evidence suggests that it serves to protect against cardiovascular overload and injury. hope has been expressed that adrenomedullin or an agonist specific for adrenomedullin receptors might find a place in the treatment of cardiovascular disorders.
Un caso de cefalea post traumática: consideraciones sobre clasificación, fisiopatología y tratamiento
Meli,M.G.;
Revista de la Sociedad Espa?ola del Dolor , 2010,
Abstract: case report of a 35 year old woman with a post traumatic headache (pth). onset of the pain three years earlier, after falling on the ground, which required resuscitation. she had to be on mechanical ventilation for 11 days and suffered several contusions on the right frontal-temporal area of the skull. on discharge, she complained of a continuous bilateral tension headache; she underwent diagnostic cervical medial branch blocks and bilateral mayor occipital nerve blocks with no findings. subsequently, a c7 stellate ganglion block (sgb) on the right side was performed with full pain relief on the same side. headache is the most prevalent symptom of post concussion syndrome. diagnostic criteria for chronic pth secondary to moderate traumatic brain injury are described in the discussion. the pathophysiology of pth is poorly understood. neuroimaging and experimental models offer novel theories to explain a common mechanism for pain in pth and primary headaches. it is assumed that a central and a peripheral sensitization may act through a common pain pathway such as the cervico-trigeminal relay. after a brain injury, pain pathways may be damaged at different levels, causing different types of pain. a clinical case is described here, in which pharmacotherapy, cervical medial branch blocks and occipital nerve blocks failed. on the other hand, sgb was effective, the reason for which might be found in the pathophysiology of the pth, as it causes a temporary block of all the sympathetic fibres to the head and neck. if pth shared the peripheral sensitization mechanism and the vasoregulation impairment with primary headaches, analgesic properties from cervicothoracic sympathetic block would be explained. this unexpected effect should stimulate a review of the international classification of headache disorders ii. stellate ganglion block should be considered as a diagnostic and therapeutic option in case of resistant headache.
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