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Effects of Low-protein or High Energy Levels Diets on Layer-type Chick Juvenile Performance
A. Teteh,K. Aklikokou,M. Gbeassor,J. Buyse
International Journal of Poultry Science , 2010,
Abstract: Effects of feed nutritive values on broiler performance are widely investigated. But, relationship between feed macronutrients levels and layer-type chicks (male and female) retains little attention. However, as for all developmental stages, starter diet composition may affect layer-type chick juvenile growth as well as physiological parameters. A total of 684 Hisex Brown layer-type chicks were studied. Chicks were divided, at random, into 3 groups with equal number of males and females: control, Low-Protein Diet (LP) and High Metabolisable Energy Diet (HME). During rearing period, feed intakes were recorded and chicks were weighed individually at the end of each week. Also, sample of chicks were used to weigh liver, at hatch and at 7, 14 and 56 day-old and to collect blood for glucose, total protein and triglyceride levels determination. Results indicate that layer-type chick growth rate, liver weight and feed efficiency were in following order HME > control > LP. With regard to chick sex, male chicks of HME and control diets grew better than female chicks from d 7 onward. But, in LP group, the weights of male and female chicks were comparable up to 49 d-old. At 7 d post-hatch, serum total protein and triglyceride levels of control chicks were higher than those of chicks of LP group while the levels of HME group were comparable to those of the two other groups. For total protein levels this trend lasted until 56 d of age. It can be concluded that low protein level of starter diet affects negatively feed efficiency and layer-type chick juvenile growth while high level of metabolisable energy improve feed efficiency and growth rate.
The medicinal and aromatic plants: their present and future status
Messanyi Gbeassor
Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas , 2006,
Abstract:
Sida acuta Burm. f.: a medicinal plant with numerous potencies
SD Karou, WMC Nadembega, DP Ilboudo, D Ouermi, M Gbeassor, C De Souza, J Simpore
African Journal of Biotechnology , 2007,
Abstract: Sida acuta is shrub belonging to Malvaceae family. The plant is widely distributed in the subtropical regions where it is found in bushes, in farms and around habitations. Surveys conducted in indigenous places revealed that the plant had many traditional usages that varied from one region to another. The most cited illnesses are fever, headache and infections diseases. Indeed, many laboratory screening have been conducted to show the scientific rationale behind these usages and many compounds have been isolated from the plant. In the present review we listed the plant usages in folk medicine in some regions where the plant grows and we discussed on the confirmed in vitro activities after laboratory screenings. The review ended with the pharmacological properties of several compounds isolated from S. acuta principally alkaloids.
Effect of mancozeb-treated lettuce (Lactuca sativa) on wistar rat liver
Y Adjrah, SD Karou, A Agbonon, K Eklu-Gadegbeku, C de Souza, M Gbeassor
Ethiopian Journal of Environmental Studies and Management , 2013,
Abstract: Vegetable contamination by pesticides presents current problem of public health. Previous studies have shown that 60% vegetables sampled collected in Lomé (Togo) have pesticide residues exceeding the tolerable limits. Because mancozeb, ethylene bis-dithiocarbamate, is mainly used, more than five times, during the growth of lettuce (Lactuca sativa), the aim of the present investigation is to evaluate the potential effect of mancozeb-treated lettuce on the rat liver physiology. Mancozeb-treated lettuce and two doses of mancozeb were administered during 28 days to rats. Along the study, animal behavior was assessed, and at the end of administration, some hepatic enzymes such as transaminases and alkaline phosphatase were studied. The decrease in rat body weight was noted and animals have soft feces. Plasmatic concentrations of transaminases, alkaline phosphatase, and total bilirubin are increased in rats administered with mancozeb-treated lettuce. The plasmatic concentration of total protein is not decreased significantly. Those results indicate that lettuce collected directly from gardens, without washing or less washed, are not fit for human consumption.
Anti-ulcer and Anti-inflammatory Effects of Hydroalcohol Extract of Aloe buettneri A. Berger (Lilliaceae)
K Metowogo, A Agbonon, K Eklu-Gadegbeku, AK Aklikokou, M Gbeassor
Tropical Journal of Pharmaceutical Research , 2008,
Abstract: Purpose: Aloe buettneri A. Berger is commonly used in Togolese folk medicine to treat inflammation and gastric ulcer. In this study we investigated the anti-oedema, analgesic, antipyretic and ulcer healing properties of the hydro-alcohol extract of their leaves. Methods: Rat oedema paw were induced by the injection of 0.1 ml of formaldehyde 1%, tail flick method is used to study analgesic property, hyperthermia was induced by subcutaneous injection of 15% of a brewers\' yeast suspension at dose of 10 ml/kg and ulcers were induced by ethanol or HCl/ethanol mixture. Results: The extract showed anti-inflammatory properties at doses between 250-500 mg/kg. It inhibited, in a dose- dependent manner, the oedema induced by 0.1 ml of formaldehyde 1%. Scores of 73.70% and 83.63% were obtned when the doses of extract administered were 100 and 500 mg/kg, respectively. The tail flick analgesic index showed an increase of 36.56% when the dose was 500 mg/kg. The extract decreased significantly the hyperthermia induced by the injection of yeast. 1000 mg/kg of the extract inhibited 63.77% of the gastric lesion induced by acid-water-ethanol mixture while daily administration of the same dose accelerated the cicatrisation of gastric ulcer induced by 95% ethanol. Conclusion: The results obtained show that the hydro-alcohol extract of Aloe buettneri A. Berger (Lilliaceae) has anti-inflammatory, anti-ulcer and wound healing properties
Acute and Sub-chronic (28-day) Oral Toxicity Studies of Hydroalcohol Leaf Extract of Ageratum conyzoides L (Asteraceae)
A Diallo, K Eklu-Gadegkeku, A Agbono, K Aklikokou, EE Creppy, M Gbeassor
Tropical Journal of Pharmaceutical Research , 2010,
Abstract: Purpose: Ageratum conyzoides is an annual herbaceous plant commonly used in African traditional medicine as a purgative, antipyretic, anti-ulcer and wound dressing agent. The objective of this study was to investigate the acute and sub-chronic toxicity of A. conyzoides leaves in Wistar rats. Methods: In the acute test, the limit test dose of 5000 mg/kg was administered to Wistar rats and then observed individually 1 h post-dosing, and at least once daily for 14 days. Sub-chronic toxicity was evaluated after administering daily oral doses of 500 and 1000 mg/kg body wt., for 28 days to the rats, Biochemical and haematological assessments as well as body and relative organ weights of the rats were carried out. Results: The limit dose of 5000 mg/kg did not cause any mortality or signs of acute toxicity in the rats tested during the observation period. In the sub-chronic tests, the results did not show any treatment–related abnormalities in terms of haematological and biochemical parameters. However, urea was significantly (p < 0.05) lower in the group treated with 500 mg/kg of A. conyzoides extract. The weekly body and organ weight of the rats showed no significant differences between the control and the rats treated with the extract except for liver where there was a significant increase (p < 0.05) in rats that received 1000 mg/kg, i.e., 3 ± 0.2 g as against 2.5 ± 0.1 g for the control. Conclusion: Our results suggest that the hydroalcohol extract of A. conyzoides is relatively safe when administered orally in rats.
Influence of Moringa oleifera leaves on atherogenic lipids and glycaemia evolution in HIV-infected and uninfected malnourished patients
A Tete-Benissan, MLA Quashie, K Lawson-Evi, K Gnandi, K Kokou, M Gbeassor
Journal of Applied Biosciences , 2013,
Abstract: Objectives: The study evaluated mineral composition of “Togolese ecotype” of Moringa oleifera leaves and its effect on anthropometric parameters, atherogenic lipids and glycaemia during nutritional recovery in HIV negative and HIV positive malnourished patients after daily use of the leaves powder. Methodology and results: Patients aged from 12 months to 8 years, consumed every day for 15 weeks the leaves powder. Results showed that powder is rich in proteins, micronutrients and induced BMI increase in both patients (p C 0.001). Biochemical parameters determination showed decrease in total cholesterol, triglycerides, LDL-cholesterol (p C 0.01), atherogenicity index (AI) correlated with HDL-cholesterol increase (p C 0.001) in HIV negative. Increase in triglycerides, LDL-cholesterol, AI (p C 0.001) correlated with HDLcholesterol decrease (p C 0.001) is observed in HIV positive. Total cholesterol decreased more in HIV positive asymptomatic and increased in patients treated with ARV drugs (p C 0.0001). Glycaemia level is decreased in both patients of the study. Conclusion and application of findings: This study confirms higher concentrations of proteins, micronutrients, hypolipidemic potential and hypocholesterolemic activity of M. oleifera leaves. This explained nutritional recovery and reduction of atherogenic lipids. Positive effect of the powder on cholesterol metabolism is due to beta-sitosterol, bioactive phytoconstituent of the leaves which fixed LDL particles and thought to be through the lowering significantly of their plasma concentrations. Reduction of glycaemia in both patients confirms also hypoglycemic properties of leaves with high concentration of polyphenols and antioxydants. The lowering of atherogenic risk and glycaemia after regular consumption of M. oleifera leaves powder is more significant in HIV negative than HIV positive patients. Results of this study bring information which will make it possible to pediatrics and nutritionists to adapt better use of M. oleifera leaves to combat malnutrition and the follow-up of HIV positive persons and in particular those on antiretroviral treatment.
Effects of Glucides on Thermal Denaturation and Coagulation of Whey Proteins Studied by Ultraviolet Spectroscopy
Etou Mongo Antoine,A.A. Abena,M. Gbeassor,H. Chaveron
Journal of Applied Sciences , 2007,
Abstract: The thermal coagulation of whey proteins concentrates was inhibited by various glucides. The disaccharides, saccharose and lactose, were most effective and the amino sugar, glucosamine, least effective in this respect. Ultraviolet absorption and light-scattering measurements on thermal denaturation and coagulation of both unfractionated and individual whey proteins (α-lactalbumin, β-lactoglobulin and bovine serum albumin) showed that saccharose promotes the denaturation of these proteins but inhibits their subsequent coagulation. These results are interpreted in terms of the effect of saccharose on the hydrophobic interactions between solvent and protein.
Effect of Dietary Intake of Fermented Seeds of Parkia biglobosa (Jacq) Benth (African Locust Bean) on Hypertension in Bogou and Goumou-kope Areas of Togo
K Ognatan, K Adi, C Lamboni, J-M Damorou, KA Aklikokou, M Gbeassor, J-C Guilland
Tropical Journal of Pharmaceutical Research , 2011,
Abstract: Purpose: To identify the possible effect of the consumption of fermented seeds of Parkia biglobosa (Jack) Benth, Mimosaceae (African locust bean) by humans on the prevention of hypertension. Methods: Two types of populations in Togo were identified and compared: one type was in a region (Bogou) where the condiment (Parkia biglobosa seeds) is highly consumed and the other people do not eat it at all (Goumou-kope). Anthropometrical, clinical and biochemical analyses were investigated in both target groups. Results: Significantly decreased blood pressure and heart beat were detected in the group of people living in Bogou’s region when compared to the non-consumption group of Goumou-kope (p < 0.001). Magnesium level was significantly increased in the Bogou group compared to that in the second group (p < 0.0001). Lower levels of low density lipoprotein-cholesterol (91± 36 vs. 110 ± 44 mg/dL, p = 0.01), triglycerides (111 ± 6 vs. 129 ± 6 mg/dL, p = 0.028), and higher levels of high density lipoproteincholesterol (63 ± 2 vs. 48 ± 3 mg/dL, p < 0.001) were observed in subjects who regularly consummed P. biglobosa fermented seeds. Furthermore, plasma glucose concentration was significantly lower in Bogou group than in Goumou-kope (68 ± 16 vs. 76 ± 15 mg/dL (p < 0.001). Conclusion: The results of the present study demonstrate that fermented seeds of Parkia biglobosa exert an anti-hypertension effect.
Antimicrobial Activities of Syzygium aromaticum (L.) Merr. and L.M. Perry (Myrtaceae) Fruit Extracts on Six Standard Microorganisms and Their Clinical Counterpart  [PDF]
Y.-G. Afanyibo, K. Anani, K. Esseh, Y. Sadji, K. Idoh, K. Koudouvo, A. Agbonon, Y. Améyapoh, K. Tozo, M. Gbeassor
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104951
Abstract:
Syzygium aromaticum is used in combination with other plants as an al-coholic infusion by traditional practitioners to treat infections. It has been selected for evaluation for its antimicrobial properties to justify its use in traditional pharmacopoeia. The fruits were used as plant material while the microbial germs consisted of six reference strains: Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Salmonella typhimurium ATCC 14028, Pseudomonas aeruginosa ATCC 27853, Shigella flexneri ATCC 12022, Candida albicans ATCC 35659 and their clinical counterparts. The extracts were obtained by aqueous decoction, hydroethanolic and ethanolic macerations. The phytochemical screening was performed by chemical staining tests. The antibiotic susceptibility test was performed using the well diffusion method and the MIC and MBC or MFC were determined using the 96-well microplate dilution method. The results showed that 66.67% of the strains tested were sensitive to the aqueous extract with inhibition diameters ranging from 15 to 21 mm and MIC and MCB or MFC between 0.0976 - 0.3906 mg/mL and 0.1953 - 07812 mg/mL respectively, thus determining bacteriostatic activity. 100% of the germs tested were sensitive to hydroethanolic and ethanolic extracts. The inhibition diameters range from 12 - 28 mm for hydroethanolic extract with MIC and MBC or MFC ranging from 0.0488 - 0.3906 mm and 0.0488 - 0.7812 mm respectively. The ethanolic extract gave inhibition diameters of 12 - 26 mm; MIC and MBC or MFC ranging from 0.0976 - 0.7812 mm. Hydroethanolic extract gave three (3) bactericidal/fungicidal activities compared to four (4) as for ethanolic extract. These results prove the use of S. aromaticum among traditional recipes for treating infections in the pharmacopoeia but further studies remain important to produce traditionally improved drugs.
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