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Search Results: 1 - 10 of 411167 matches for " M. Carmen Lobo "
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Growth of Four Varieties of Barley (Hordeum vulgare L.) in Soils Contaminated with Heavy Metals and Their Effects on Some Physiological Traits  [PDF]
águeda González, M. Carmen Lobo
American Journal of Plant Sciences (AJPS) , 2013, DOI: 10.4236/ajps.2013.49221

To evaluate the effect of zinc (Zn), cadmium (Cd), and chromium (Cr) on growth and selected physiological traits in barley, a greenhouse trial was performed using four barley varieties that were exposed to different concentration of these metals. The parameters quantified were growth, chlorophyll content, and chlorophyll fluorescence during three phenological stages: flag leaf, anthesis, and grain filling. The metal concentrations in both the plant and soil were also quantified. We determined that the varieties studied were more tolerant to Zn and Cd than to Cr. Treatment with Zn did not negatively affect growth, and only high concentrations of Cd decreased growth by approximately 4% to 8%. Plants treated with the highest Cr concentration stopped growing at the flag leaf stage. The amount of metal that accumulated in the plant increased with increasing metal concentration, and the highest amount of accumulated metal was recorded in the root and shoot. Both the plant height and dry weight were higher in the CB502 variety plants, followed by the Reinette, Pedrezuela, and Plaisant varieties. The same trend was observed for the chlorophyll content and fluorescence, with a significant correlation between the growth parameters and chlorophyll content (p < 0.001). Thus, we determined that barley has variability in the studied traits.

Homenaje al Dr.Solón Nú ez Frutos en su 125 aniversario de nacimiento
Carmen Lidia Guerrero Lobo
Revista Costarricense de Salud Pública , 2006,
Efecto del pisoteo en sistemas de producción de cerdos a campo sobre propiedades del suelo
Rodríguez M,Adriana; Pulido M,Mansonia A; Rey B,Juan C; Lobo L,Deyanira; Araque,Humberto; Rivero,Carmen;
Agronomía Tropical , 2010,
Abstract: the objective of this study was to evaluate the tendency of changes produced by the trampling in production systems from pigs to fi eld (pf) on the properties of a mollisol ground of venezuela. the sampling was based with pigson a factorial design 2x3, a factor of two levels: pastures (pwp) and pig paddocks without (ppw) and soil depth atf three levels (0-5, 5-10 y 10-20 cm). in each plot four points were selected at random according to previous variability analysis. at each point was determined ph, electrical conductivity (ec) and organic carbon (oc) content of the soil, and assessing structural condition, structural stability to wet sieving, drop impact, and water movement. the results showed significant differences between treatment for the variables bulk density (bd), pores with radio <15 μm, mechanical resistance to the penetration (mrp) and oc, while for ph and ec only significant differencesby effect of the presence or absence of pigs. this suggest that pigs trampling have an modifier effect on soil properties evaluated, in this case further evidence of negative changes such as, increase of bd and pores with radio <15 μm and the diminution of the total porosity and infiltration rate
Effect of Zn, Cd and Cr on growth, water status and chlorophyll content of barley plants (H. vulgare L.)  [PDF]
águeda González, Valerio Chumillas, María del Carmen Lobo
Agricultural Sciences (AS) , 2012, DOI: 10.4236/as.2012.34069
Abstract: To evaluate the potential of barley for the phytoremediation of soils contaminated by metals, we conducted a growth chamber experiment with plants exposed to various concentrations of Zn, Cd and Cr. Growth parameters, chlorophyll content and chlorophyll fluorescence were measured at 15 and 29 days after treatment application, and the metal concentration in the aerial part of the plant, the root and the soil was also measured. In all cases, the amount of metal accumulated in the plant increased by increasing the concentration of the applied metal, and the roots accumulated more metal than did the aerial part of the plant. The amount of Cr found in the soil was significantly lower than that of Cd and Zn. The toxic effect of Zn and Cd on the plant was low, affecting growth only at the highest concentrations. For Zn and Cd at the concentrations used, the decrease in water content was 14% compared with the control and 26% for Cr. For plants treated with the highest metal concentrations, the most significant differences were found in chlorophyll content, which had the lowest values compared with the control (23% for Zn, and 42% for Cd and Cr), and in chlorophyll fluorescence (2% for Zn, 23% for Cd and 29% for Cr). These decreases occurred 29 days after applying the Zn and Cd treatments. In plants treated with Cr, the decrease occurred 15 days after treatment application. Under our experimental conditions, barley is more tolerant to Zn and Cd than to Cr.
Creatinina sérica elevada en el paciente hipotiroideo: miopatía o verdadera nefropatía? Propuesta de clasificación
Guerrero-Lobo,Carmen Lidia;
Acta Médica Costarricense , 2009,
Abstract: background: in patients with hypothyroidism is possible to find an increased serum creatinine not only due to renal failure but to myopathy in presence of normal renal function. two patients, each representing 1 type of a proposed classification regarding thyroid dysfunction and abnormal creatinine are presented, in order to communicate this relationship, until now based on isolated reports. the first individual had an increased serum creatinine with normal renal function due to hypothyroid myopathy (type 1). rhabdomyolysis related to this myopathy is pointed as a cause of acute renal failure. the 2nd patient had an increased serum creatinine with abnormal kidney function (type 2), which improved when he became euthyroid after levothyroxine administration. the diagnosis of hypothyroidism is often missed in patients with altered renal function, if it becomes evident and is properly treated the renal function will improve. as is known hypothyroidism causes hypercholesterolemia, if such patient unknowingly receives statins or gemfibrozil, severe rhabdomyolysis and renal falilure may occur, as reported in the literature. the 3d category of the classification is the occurrence of nephrotic syndrome in hypothyroid patients who discontinue t4 treatment due to thyroid cancer for further studies or by patient non adherence, developing significant proteinuria few months later. kidney biopsy lesions vary from membranous glomerulopathy to membranoproliferative glomerulonephritis. these findings will resolve with the administration of levothiroxine, without glucocorticoids. however patients with nephrotic syndrome related to hashimoto thyroiditis will improve with glucocorticoids. conclusion: 1. tsh must be requested when: a) there is an increased serum creatinine or hypercholesterolemia without a clear cause. b) in patients with rabdomyolysis or acute renal failure with increased ck since it may be secondary to hypothyroid myopathy. 2. serum creatinine should be requested in hy
Creatinina sérica elevada en el paciente hipotiroideo: miopatía o verdadera nefropatía? Propuesta de clasificación Elevated Serum Creatinine in Hypothyroidism: Myopathy or Real Nephropathy ? Classification Proposal
Carmen Lidia Guerrero-Lobo
Acta Médica Costarricense , 2009,
Abstract: Justificación: En el paciente hipotiroideo la creatinina sérica puede aumentar no solo por fallo renal, sino también por miopatía en presencia de función renal normal. Se reportan 2 pacientes representativos de sendos tipos de la clasificación aquí propuesta sobre la asociación disfunción tiroidea / creatinina sérica. El primer enfermo presenta aumento de la creatinina sérica secundario a miopatía hipotiroidea con función renal normal (tipo 1), esta se puede complicar con rabdomiolisis y causar insuficiencia renal aguda en hipotiroideos no diagnosticada. El otro paciente con creatina sérica alta mejoró su función renal al tratarse su hipotiroidismo (tipo 2). Ocasionalmente, este ha permanecido oculto y al ser diagnosticado y tratado, se mejora la función renal. El hipotiroidismo cursa con hipercolesterolemia y si no se valora la función tiroidea y se administran estatinas, se empeora el da o muscular del paciente. Lo mismo ha sucedido con el uso de gemfibrozil en condiciones similares. El tercer tipo de da o renal relacionado con hipotiroidismo es la proteinuria en rango de síndrome nefrótico, vinculada con suspensión de la levotiroxina. Las biopsias muestran lesiones histológicas de diversas glomerulopatías, que mejoran con la administración de levotiroxina. En pacientes con tiroiditis de Hashimoto aparecen otras glomerulopatías que responden a los glucocorticoides. Conclusión: 1) La hormona estimulante de la tiroides (TSH por sus siglas en inglés) debe cuantificarse en pacientes con creatina sérica aumentada, en aquellos con colesterol elevado sin una causa evidente y en los que tienen polimiositis o rabdomiolisis con creatina fosfocinasa elevada e insuficiencia renal aguda. 2) Se debe solicitar creatina sérica a los pacientes hipotiroideos que usan amiodarona y a quienes suspenden el tratamiento con levotiroxina, pues pueden presentar disminución de su función renal. 3) Un paciente hipotiroideo que descontinuó la levotiroxina puede desarrollar un síndrome nefrótico que puede responder al tratamiento con glucocorticoides o levotiroxina, si su origen es inmunológico o no. Background: In patients with hypothyroidism is possible to find an increased serum creatinine not only due to renal failure but to myopathy in presence of normal renal function. Two patients, each representing 1 type of a proposed classification regarding thyroid dysfunction and abnormal creatinine are presented, in order to communicate this relationship, until now based on isolated reports. The first individual had an increased serum creatinine with normal renal function due to hypoth
The Presence of Mutations in the K-RAS Gene Does Not Affect Survival after Resection of Pulmonary Metastases from Colorectal Cancer
Jon Zabaleta,Borja Aguinagalde,José M. Izquierdo,Nerea Bazterargui,Stephany M. Laguna,Maialen Martin-Arruti,Carmen Lobo,José I. Emparanza
ISRN Surgery , 2014, DOI: 10.1155/2014/157586
Abstract: Introduction. Our objective was to identify mutations in the K-RAS gene in cases of pulmonary metastases from colorectal cancer (CRC) and determine whether their presence was a prognostic factor for survival. Methods. We included all patients with pulmonary metastases from CRC operated on between 1998 and 2010. K-RAS mutations were investigated by direct sequencing of DNA. Differences in survival were explored with the Kaplan-Meier method log-rank tests and multivariate Cox regression analysis. Results. 110 surgical interventions were performed on 90 patients. Factors significantly associated with survival were disease-free interval , age , number of metastases , lymph node involvement , size of the metastases , and previous liver metastasis . Searching in 79 patients, K-RAS mutations were found in 30 cases. We did not find statistically significant differences in survival comparing native and mutated K-RAS. We found a higher rate of lung recurrence and shorter time to recurrence in patients with K-RAS mutations. Gly12Asp mutation was associated with higher recurrence and lower survival . Conclusions. The presence of K-RAS mutations in pulmonary metastases does not affect overall survival but is associated with higher rates of pulmonary recurrence. 1. Introduction In general, the development of cancer is the consequence of a gradual accumulation of genetic alterations. These cause a progressive transformation of normal human cells into malignant cells [1]. The RAS family of genes have the highest known rate of mutations in human cancer, and the aberrant activation of the RAS gene due to a mutation leads to an overexpression of Ras proteins, causing changes in the cells that lead to proliferation, invasion, and metastasis [2]. The conversion of Ras of a protooncogene to an oncogene generally occurs as a consequence of a single mutation in the gene. The mutations are found most often in codon 12 of the gene, followed by condon 13 [3]. In the normal human gene, codon 12 has the sequence CGT that codes for the amino acid glycine (Gly). Any change leading to a loss of the Gly residue at codon 12 may change a normal Ras gene into one that is potentially carcinogenic [3]. Similarly, changes in the Gly residue at codon 13 have the same effect [3]. In recent years, researchers have identified over 20 oncogenes, mutations of which contribute to the occurrence of solid tumours in humans [4]. In colorectal carcinoma, the most common mutations are located in the K-RAS, PIK3CA, BRAF, and N-RAS genes [4]. Recently, Tie reported, in the journal Clinical Cancer
Habilidad de cuidado de cuidadores familiares principales de pacientes con ACV: Cartagena (Colombia)
Montalvo Prieto,Amparo; Badrán Navarro,Yineth; Cavadías Puello,Catherine; Medina Ripoll,Elisabeth; Méndez Soraca,Karina; Padilla Lobo,Carmen; Ruidiaz Gómez,Keydi;
Revista Salud Uninorte , 2010,
Abstract: cerebrovascular accident (cva) is the neurological disease that causes more disability and institutionalization. its high survival is not even a full recovery, since until ninety percent suffer consequences, creating a demand for care and the presence of a caregiver to perform the basic activities. these caregivers are exposed to suffer changes in their lives that affect different roles, making them a vulnerable population that requires care from health services. objective: identify the skills of care from care givers of patients with sequelae of cva in cartagena. method: descriptive study, made to 152 caregivers of patients with sequelae of cva in the city of cartagena. it was used two instruments, characterization of the care givers and inventory caregiver's ability to care, an instrument that measures the ability of care in the dimensions knowledge, courage and patience. results: caregivers are mostly women in adulthood, younger than the subject of care, homemakers. they have more than 37 months devoted to the care, generally there are more carers, they have first degree of consanguinity (51.3%), and average ability to care. the dimensions of caring ability, knowledge (75.7%) patience (87.5%) and courage (2.6%) were in the high category. conclusions: caregivers of people with acv, do not have the skills necessary to establish the relationship of care, interventions are needed to reduce the risks of the caregiver role.
Protocolo largo con análogos de GnRH versus protocolo corto con antagonistas: ?existen diferencias en cuanto a los resultados de los ciclos de FIV-ICSI?
Blasco G,Laura; Armijo S,Onica; Castro M,Bárbara; Lobo M,Sonia; González V,Carolina; Montejo G,Juan Manuel; Cuadrado M,M. Carmen; Fernández M,Beatriz;
Revista chilena de obstetricia y ginecología , 2011, DOI: 10.4067/S0717-75262011000500002
Abstract: aims: to assess if there exist any differences in the results of the ivf-icsi cycles depending on the stimulation protocol employed. methods: retrospective descriptive study of infertile patients who underwent ivf-icsi cycles at la paz university hospital, between january and september 2010, comparing sitmula-tion protocol with gnrh agonists vs antagonists of gnrh. the variables analyzed were pregnancy rate, cancellation rate, total dose of gonadotropin required for stimulation, serum estradiol levels on the day of hcg administration, number of follicles punctured, complexes obtained, number of mature oocytes and of embryos obtained. results: no statistically significant differences where found in the results of cycles depending on the protocol of stimulation used in any of the variables analyzed. conclusions: this study didn't find any difference in the outcome of ivf-icsi cycles in relation to the use of gnrh agonists or antagonists. we need more studies with larger sample sizes to determine which is the best treatment to each patient in order to achieve optimal results.
Crecimiento de ni?os "normales" de la ciudad de Córdoba (Argentina),en el primer a?o de vida, 1993-1994. Estudio CLACYD
Agrelo M,Fernando; Sabulsky L,Jacobo; Lobo M,Beatriz; Batrouni K,Lucia; S.de Roitter,Hebe Goldenhersch; Villafa?e R,Liliana; Mongiano N,Carmen; Berra R,Silvina; Chesta B,Mónica;
Revista chilena de pediatría , 1998, DOI: 10.4067/S0370-41061998000500006
Abstract: this article describes some growth parameters of "normal" children from the city of cordoba, argentina, in their fist year of ire (atbirth, 6 and 1 2 months). a reoresentative cohort from different social levels was studiea. anthropometric examinations were carried cut, according to standardized methods at ages previously noted. means, standard deviations and percentiles of weight, length and head circumference are reported. moles showed higher values for the high-mecr social level showed higher values for weight af born (p < 0.02|, end both boys and girls from this social level showed a higher height value than the other social evils analyzed. local values were compared with one study fro-n the city of la plata and nchs. in order to find out if the studied population survey reaches the coals from who for the year 2000, percentile 10 of weight and length from cordoba was compared with pierce-tile 3 from nchs. it is important that these tables be used in future research in order to evaluate its adequacy to the growth pattern of children from cordoba, other regions of argentina or ether countries with similar genetic and environmental background.
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