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Search Results: 1 - 10 of 407443 matches for " M?nica Diuana;Monteiro "
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The rabbit as an animal model for experimental surgery
Calasans-Maia, Mnica Diuana;Monteiro, Maria Lucia;áscoli, Fábio Oliveira;Granjeiro, José Mauro;
Acta Cirurgica Brasileira , 2009, DOI: 10.1590/S0102-86502009000400014
Abstract: the white new zealand rabbit (oryctolagus cuniculus) is frequently used as a model for in vivo studies. however, information on precautions when using this animal as an experimental model is limited. this review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. based upon the literature and our own experience with white new zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.
Avalia??o histológica comparativa de reparo ósseo em tíbia de coelho tratada com xenoenxertos
Calasans-Maia, Mnica Diuana;Ascoli, Fabio Oliveira;Novellino, Adriana Terezinha Neves Alves;Rossi, Alexandre Malta;Granjeiro, José Mauro;
Acta Ortopédica Brasileira , 2009, DOI: 10.1590/S1413-78522009000600005
Abstract: objective: xenografts are an alternative to autogenous grafts and must be osteoconductive and biocompatible. a recent study has demonstrated that the physical and chemical characteristics of commercially available hydroxyapatites do not fit the manufacturers' descriptions. this study evaluates the biocompatibility and osteoconduction of a xenograft derived from bovine medullary bone. methods: fifteen adult rabbits weighing between 2,500 g and 3,000 g each were anesthetized and subjected to surgical procedures to create three perforations in the tibia, with a diameter of 2 mm. these were filled with blood clot, osseus? and bio-oss?. the animals were euthanized after 7, 14 and 28 days. results: histopathological analysis of the interface between the bone and the biomaterial showed a slight inflammatory response after 7 days, which was absent in the subsequent periods. both materials were partially replaced by bone tissue directly in contact with the surface of the materials, without the occurrence of fibrosis. conclusion: we concluded that both materials are biocompatible and absorbable, allowing for progressive bone apposition on the surface throughout the evaluation period.
Saúde em pris?es: representa??es e práticas dos agentes de seguran?a penitenciária no Rio de Janeiro, Brasil
Diuana, Vilma;Lhuilier, Dominique;Sánchez, Alexandra Roma;Amado, Gilles;Araújo, Leopoldina;Duarte, Ana Maria;Garcia, Mnica;Milanez, Eliane;Poubel, Luciene;Romano, Elizabeth;Larouzé, Bernard;
Cadernos de Saúde Pública , 2008, DOI: 10.1590/S0102-311X2008000800017
Abstract: the role of prison guards in limiting access to health services by inmates and the impact of their representations on daily health practices were investigated through an action-research program. the program aimed to produce knowledge and improve the guards' involvement in tuberculosis and hiv/aids control by raising their awareness. developed in three prisons and two hospitals, the study included individual interviews and group discussions and showed that representations of health and illness, risk hierarchy, and preventive strategies are related to actors' status in the prison's social organization, the conflicts and tensions between them, and the sense of group belonging that reinforces identities and antagonisms. such representations have a major influence on the guards' daily practices and inmates' access to health services. the denial of inmates' right to health and their limited autonomy contributed to the implementation of essentially prescriptive health actions. the guards' awareness of their own health representations and practices may contribute to the deconstruction of stereotypes and increase their involvement in prevention and care. further, improvement of inmates' health depends on changes in prison conditions.
Desigualdades sociais no uso de interna??es hospitalares no Brasil: o que mudou entre 1998 e 2003
Castro,Mnica Silva Monteiro de;
Ciência & Saúde Coletiva , 2006, DOI: 10.1590/S1413-81232006000400020
Abstract: the objective of this paper was to compare hospital admission associated factors in brazil in 1998 and 2003. the data of the 2003 national household survey health supplement were analyzed using a logistic regression model with normalized weights, using andersen's behavioral model, and the results were compared to those published in the pnad 1998. there was a decrease in hospital admission coefficients for women in reproductive age and older adults, and an increase in the coefficient for children. for adults, there was an increase in inequality in hospital admissions according to the income. among children, those with no income had more chances for hospital admission. race and educational level had no influence in hospital admissions. some general trends with respect to hospital admissions in brazil could be verified in this study: the increase in admissions for surgical procedures, the decrease in admissions related to pregnancy, childbirth and puerperium, shorter in-patient care, the increase in admissions to public hospitals, the increase in admissions financed by the brazilian unified health system (sus) in comparison to admissions covered by private health insurances and out-of-pocket payment, the decrease in admissions financed by more than one system and the great proportion of users satisfied with the care they received.
Leaf Essential Oil from Three Exotic Mytaceae Species Growing in the Botanical Garden of Rio de Janeiro, Brazil  [PDF]
Antonio C. Siani, Marcos J. Nakamura, Gabrielle P. das Neves, Sérgio da S. Monteiro, Mnica Freiman S. Ramos
American Journal of Plant Sciences (AJPS) , 2016, DOI: 10.4236/ajps.2016.76079
Abstract: The leaf essential oils of three Myrtaceae species: Melaleuca leucadendra, Lophostemon confertus and Ugni molinae, non-native to Brazil and growing in the Rio de Janeiro Botanical Garden, were obtained by hydrodistillation and analyzed by GC and GC-MS. Oil yields from fresh leaves were 0.76%, 0.08%, and 0.04%, respectively. Sixty-seven percent of M. leucadendra oil was made up of monoterpenes, wherein 1,8-cineole was largely predominant (49%), followed by α-terpineol (7.6%) and terpinen-4-ol (4.3%). The sesquiterpene profile was characterized by a significant amount of viridiflorol (29%). Oil from L. confertus was 42% monoterpenes; the most predominant constituents being α-pinene (20.8%) and α-thujene (7.1%). Total sesquiterpenes (55.4%) comprised spathulenol (28%), globulol (14%), and aromadendrene derivatives (8.5%) as the main species. U. Molinae
Agrupamento da Classifica??o Internacional de Doen?as para análise de reinterna??es hospitalares
Castro, Mnica S. Monteiro de;Carvalho, Marilia Sá;
Cadernos de Saúde Pública , 2005, DOI: 10.1590/S0102-311X2005000100035
Abstract: icd chapters and three-digit categories are not always appropriate for epidemiological analysis; the former are too generic and the latter too numerous. when the epidemiological focus is not on a specific clinical diagnosis, an intermediate grouping proposal between these two possibilities becomes necessary. such proposals are not frequent in the literature. we used a two-stage grouping proposal based on hospital admissions volume, internal clinical coherence in each group, and the results of a cox multivariate model for real data. as a result, we obtained 26 groups for adults and 19 groups for children, among which we chose hernia as the reference category for adults and appendiceal disease for children. the grouping proved adequate for the analysis of readmissions in a large brazilian general hospital. procedures similar to those described in this research report can be used to analyze other health problems.
Agrupamento da Classifica o Internacional de Doen as para análise de reinterna es hospitalares
Castro Mnica S. Monteiro de,Carvalho Marilia Sá
Cadernos de Saúde Pública , 2005,
Abstract: Para fins de análise epidemiológica, os capítulos da CID e as categorias de três dígitos nem sempre s o apropriadas, os primeiros por serem muito abrangentes e os segundos por serem muito numerosos. Quando o interesse epidemiológico n o recai sobre diagnósticos específicos, propostas de agrupamento intermediárias entre estas duas possibilidades se fazem necessárias. Tais propostas n o aparecem com freqüência na literatura. Nós utilizamos uma proposta de agrupamento, que foi baseada no volume de interna es, em duas etapas: na coerência clínica interna de cada grupo e nos resultados do ajuste de um modelo de Cox multivariado para dados reais. Obtivemos como resultado 26 grupos para adultos e 19 grupos para crian as, entre os quais escolhemos como categoria de referência hérnia para adultos e doen a do apêndice para crian as. O agrupamento obtido se mostrou adequado para a análise de reinterna es hospitalares em um grande hospital geral brasileiro. Procedimentos semelhantes ao descrito nesta nota de pesquisa podem ser utilizados para a análise de outros problemas de saúde.
Reference Gene Selection and Validation for the Early Responses to Downy Mildew Infection in Susceptible and Resistant Vitis vinifera Cultivars
Filipa Monteiro, Mónica Sebastiana, Maria Salomé Pais, Andreia Figueiredo
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0072998
Abstract: The pivotal role of cultivated grapevine (Vitis vinifera L.) in many countries economy is compromised by its high susceptibility to Plasmopara viticola, the causal agent of downy mildew disease. Recent research has identified a set of genes related to resistance which may be used to track downy mildew infection. Quantification of the expression of these resistance genes requires normalizing qPCR data using reference genes with stable expression in the system studied. In this study, a set of eleven genes (VATP16, 60 S, UQCC, SMD3, EF1α, UBQ, SAND, GAPDH, ACT, PsaB, PTB2) was evaluated to identify reference genes during the first hours of interaction (6, 12, 18 and 24 hpi) between two V. vinifera genotypes and P. viticola. Two analyses were used for the selection of reference genes: direct comparison of susceptible, Trincadeira, and resistant, Regent, V. vinifera cultivars at 0 h, 6, 12, 18 and 24 hours post inoculation with P. viticola (genotype effect); and comparison of each genotype with mock inoculated samples during inoculation time-course (biotic stress effect). Three statistical methods were used, GeNorm, NormFinder, and BestKeeper, allowing to identify UBQ, EF1α and GAPDH as the most stable genes for the genotype effect. For the biotic stress effect, EF1α, SAND and SMD3 were the most constant for the susceptible cultivar Trincadeira and EF1α, GAPDH, UBQ for the resistant cultivar Regent. In addition, the expression of three defense-related transcripts, encoding for subtilisin-like protein, CYP and PR10, was analysed, for both datasets, during inoculation time-course. Taken together, our results provide guidelines for reference gene(s) selection towards a more accurate and widespread use of qPCR to study the first hours of interaction between different grapevine cultivars and P. viticola.
Compara??o de dados sobre homicídios entre dois sistemas de informa??o, Minas Gerais
Castro,Mnica S Monteiro de; Assun??o,Renato M; Durante,Marcelo Ottoni;
Revista de Saúde Pública , 2003, DOI: 10.1590/S0034-89102003000200002
Abstract: introduction: there is much criticism on the quality of criminal data available in brazil, but there lacks systematic studies to corroborate it. thus, it was conducted a comparison between homicides registered in minas gerais by two public information systems. methods: the number of homicide deaths of the mortality information system of the ministry of health (sim/ms) and minas gerais military police (pmmg), from 1979 to 1998, were assessed. the comparison between the two systems was performed using the ratio between absolute numbers, considering the municipalities categorized in five groups according to the population size in 1998, and homicide rates. two linear regression models were adjusted for rates in time, one for each system. results: in cities with less than 100,000 inhabitants pmmg homicide data is more complete than sim/ms one. in cities with more than 100,000 inhabitants, sim/ms registry is capable of providing homicide deaths data more efficiently, although it can include homicide deaths perpetrated in other municipalities and violent deaths of unknown nature that have not been due to homicide. the under-registration of pmmg in these municipalities can be due to late deaths in hospitals that are not followed up by pmmg. conclusions: pmmg and sim/ms systems represent the lower and upper limits of actual homicide deaths in larger cities. both data sources should be analyzed and compared when both are available; when only one of them is available, the analysis should take into account the differences indicated in this study.
Compara o de dados sobre homicídios entre dois sistemas de informa o, Minas Gerais
Castro Mnica S Monteiro de,Assun??o Renato M,Durante Marcelo Ottoni
Revista de Saúde Pública , 2003,
Abstract: INTRODU O: Existem muitas críticas à qualidade dos dados criminais existentes no Brasil, mas há pouco estudo sistemático para corroborar essas críticas. Nesse sentido, foi feito estudo com o objetivo de comparar o número de homicídios registrados entre dois sistemas públicos de informa o. MéTODOS: Foram analisados os óbitos registrados pelo Sistema de Informa es de Mortalidade do Ministério da Saúde (SIM/MS) e pela Polícia Militar (PMMG), de 1979 a 1998. A compara o entre os dois sistemas foi feita pela raz o entre os números absolutos, categorizando os municípios em cinco grupos de acordo com o tamanho da popula o em 1998, e pelas taxas de homicídio. Foram ajustados dois modelos de regress o linear das taxas no tempo, um para cada sistema. RESULTADOS: Nas cidades de menos de 100.00 habitantes, as informa es de homicídios da PMMG s o mais completas do que as do SIM/MS. Nas cidades de mais de 100.000 habitantes, o SIM/MS é capaz de recuperar mais eficientemente os óbitos, embora possam ser incluídos indevidamente óbitos de homicídios cometidos em outros municípios e óbitos por arma branca e de fogo de inten o indeterminada que n o tenham sido devido a homicídio. O sub-registro da PMMG pode ser devido às mortes hospitalares tardias, que n o s o acompanhadas pela PMMG. CONCLUS ES: Os sistemas do SIM/MS e PMMG representam limites superiores e inferiores do número real de homicídios ocorridos nas grandes cidades. Sugere-se que, quando disponíveis, as duas fontes sejam analisadas e comparadas; quando apenas uma delas estiver disponível, prop e-se que a análise deva considerar as diferen as.
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