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Search Results: 1 - 10 of 400815 matches for " M Esser "
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Primary immunodeficiency diseases: ‘Look deeper into nature, and then you will understand everything better.’ – Albert Einstein
S Buldeo, M Suchard, M Esser
Continuing Medical Education , 2012,
Neurodevelopmental status of HIV-exposed but uninfected children: A pilot study
P Springer, B Laughton, M Tomlinson, J Harvey, M Esser
South African Journal of Child Health , 2012,
Abstract: Introduction. HIV affects children both directly and indirectly, with evidence of increased infectious mortality and morbidity in the HIV-exposed but uninfected (HEU) infant. There is little published research on neurodevelopmental outcome of HEU infants in Africa. Following the introduction of successful prevention of mother-to-child transmission programmes, it has become important to determine whether differences exist between HEU infants and infants born to HIV-negative mothers in order to guide current management policies of this rapidly growing group of infants. Objectives. To compare the developmental outcome of infants exposed to HIV in utero who remained uninfected (HEU) with that of infants unexposed to HIV in utero (HUU). Methodology. This was a prospective, blinded, hospital-based study. Infants aged between 17 and 19 months were assessed on the Griffiths Mental Developmental Scales (GMDS). Birth history, previous hospitalisation, maternal and infant characteristics, antiretroviral exposure, anthropometric measurements and abnormal clinical findings were documented. Results. Of the original 55 infants enrolled at 2 weeks of age, 37 (17 HEU and 20 HUU) underwent neurological and developmental assessment. There were no significant differences between the groups with regard to the GMDS general quotient or other subscales, apart from the Personal/social subscale, where the HEU group performed significantly more poorly than the HUU participants (p=0.026). This difference is probably a result of cultural differences between the groups, as 76% of HEU and only 15% of HUU participants were of Xhosa origin. Discussion. There was no difference in neurodevelopmental outcome at 18 months between the HEU and HUU groups.
Polymorphisme de la phosphoglucomutase (PGM) dans l'espèce bovine
M Ansay, R Hanset, J Esser-Coulon
Genetics Selection Evolution , 1971, DOI: 10.1186/1297-9686-3-4-413
La malate déshydrogénase mitochondriale: variants électrophorétiques de nature héréditaire dans l'espèce bovine
M Ansay, R Hanset, J Esser-coulon
Genetics Selection Evolution , 1971, DOI: 10.1186/1297-9686-3-3-235
Can I-124 PET/CT Predict Pathological Uptake of Therapeutic Dosages of Radioiodine (I-131) in Differentiated Thyroid Carcinoma?  [PDF]
Gauke K. Lammers, Jan Paul Esser, Pieternel C. M. Pasker, Marina E. Sanson-van Praag, John M. H. de Klerk
Advances in Molecular Imaging (AMI) , 2014, DOI: 10.4236/ami.2014.43004
Introduction: The aim of the study was to assess the role of I-124 PET/CT in the prediction of uptake of a therapeutic dosage I-131 during follow-up of patients with differentiated thyroid cancer (DTC). Methods: The results of 34 I-124 PET/CT scans performed in our hospital between 2007 and 2012 were retrospectively evaluated. All scans were made in patients under follow up, replacing the diagnostic I-131 or I-123 scintigraphy. In all cases thyroglobulin (Tg) was stimulated (by recombinant thyroid stimulating hormone (rhTSH) or thyroid hormone withdrawal). A dosage of 40 MBq I-124 was used, with scans at 24 hours and 96 hours after administration. Results were compared to subsequent I-131 post-treatment scans (6 cases) and a combination of follow up, stimulated Tg and other imaging tools results available to assess presence of recurrence. Results: Recurrence of DTC was found in 14/34 cases. I-124 PET/CT correctly detected recurrence in 2 cases, with false negative results in 12 cases. In 1 case a false positive I-124 PET/CT result was recorded. 19 true negative results were found. For I-124 PET/CT this meant a sensitivity of 14% and a specificity of 95%. Positive predictive value was 67%, negative predictive value 61%. Post-treatment I-131 uptake (6 cases) was correctly predicted in 1 case, with false negative results in 4 cases and 1 true negative result. Conclusions: In this study I-124 PET/CT did not reliably detect recurrent differentiated thyroid carcinoma. More importantly it failed to predict I-131 uptake on post-treatment scintigraphy in a significant number of cases, which would lead to under-treatment.
Genetics of fungi: retrospect and perspective
K. Esser
Micología Aplicada Internacional , 2001,
Abstract: This short survey on fungal genetics in the 20th century reflects the course of development from classical to molecular genetics and its implication to biotechnology.
Dendrochernes cyrneus (Arachnida: Pseudoscorpiones: Chernetidae) in Brandenburg
Esser, Jens
Arachnologische Mitteilungen , 2011, DOI: 10.5431/aramit4203
Abstract: The pseudoscorpion Dendrochernes cyrneus (L. Koch, 1873) is recorded for the first time in Brandenburg (Germany). The specimen was found in the ancient park of Sanssouci under the bark of a branch of a beech tree. The suitability of D. cyrneus as an indicator species for old-growth woodlands is discussed.
Comparative International Communication Projects: Overcoming the Challenges
Frank Esser
Brazilian Journalism Research , 2011,
J. Venema, Kiliaen van Rensselaer (1586-1643): Designing a New World
R. Esser
BMGN : Low Countries Historical Review , 2011,
Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility
Aidan Casey,Edward M. Fox,Stephan Schmitz-Esser,Aidan Coffey,Olivia McAuliffe,Kieran Jordan
Frontiers in Microbiology , 2014, DOI: 10.3389/fmicb.2014.00068
Abstract: Listeria monocytogenes is a virulent food-borne pathogen most often associated with the consumption of “ready-to-eat” foods. The organism is a common contaminant of food processing plants where it may persist for extended periods of time. A commonly used approach for the control of Listeria monocytogenes in the processing environment is the application of biocides such as quaternary ammonium compounds. In this study, the transcriptomic response of a persistent strain of L. monocytogenes (strain 6179) on exposure to a sub-lethal concentration of the quaternary ammonium compound benzethonium chloride (BZT) was assessed. Using RNA-Seq, gene expression levels were quantified by sequencing the transcriptome of L. monocytogenes 6179 in the presence (4 ppm) and absence of BZT, and mapping each data set to the sequenced genome of strain 6179. Hundreds of differentially expressed genes were identified, and subsequent analysis suggested that many biological processes such as peptidoglycan biosynthesis, bacterial chemotaxis and motility, and carbohydrate uptake, were involved in the response of L. monocyotogenes to the presence of BZT. The information generated in this study further contributes to our understanding of the response of bacteria to environmental stress. In addition, this study demonstrates the importance of using the bacterium's own genome as a reference when analysing RNA-Seq data.
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