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Search Results: 1 - 10 of 30017 matches for " Luis Mayor "
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Polyphenol extraction from grape wastes: Solvent and pH effect  [PDF]
Celia M. Librán, Luis Mayor, Esperanza M. Garcia-Castello, Daniel Vidal-Brotons
Agricultural Sciences (AS) , 2013, DOI: 10.4236/as.2013.49B010
Abstract:

World wine industry transforms 10% - 25% of raw grapes into residues, mainly represented by lees, grape marcs, seeds and stems. These by-products are a rich source of polyphenols and therefore they can be used to produce new added value products. The aim of this work wasto determine the best process conditions(treatment time, % of ethanol and pH of the solvent)during solid-liquid extraction of polyphenolsfrom grape marcs, by analyzing the phenolic content of the extracts, namely: total polyphenol content, flavanols, flavonols, phenolic acids and anthocyanins. Antioxidant activity of the extracts was also determined. An extraction time of two hours was enough since longer times did not increase process yields. Best extraction yields were obtained for 75% ethanol solutions. Basic pH led to better yields in extracting media with low percentage of ethanol, whereas acid pH presented better extraction yields in extracting media with high percentage of ethanol. Among all the polyphenols extracted, anthocyanins were themost abundant representing over 40% of the total. In general, the best process conditions were 2 h ofextraction in a 75% EtOH liquid mixture at pH =2.

Water sorption isotherms of globe artichoke leaves  [PDF]
Luis Mayor, Alejandro Calvo, Ramon Moreira, Pedro Fito, Esperanza Garcia-Castello
Agricultural Sciences (AS) , 2013, DOI: 10.4236/as.2013.49B011
Abstract: One third of the artichoke production is used in industrial processes, where up to 70% - 85% of the initial raw material is transformed into solid wastes. For an adequate management of these wastes, it is necessary to know their water sorption properties, because physical, chemical andbiological changes which occur during theirstorage depend on water-solid interactions. The objectives of this work are to experimentally determine equilibrium sorption (adsorption anddesorption) data of artichoke wastes at different temperatures (25°C - 55°C), as well as correlate and predict water sorption isotherms using bibliographic models. Equilibrium moisture content ranged 0 - 0.6 kg water/kg dry solid (water activity 0.05 - 0.9). Water sorption isotherms were classified between Types II and III. Hysteresis phenomenon was not observed, neither was the dependence of the equilibrium data with temperature. BET, GAB, Oswin and Peleg correlation models were satisfactorily fitted to experimental data. A predictive model based on composition and physical state of artichoke waste components was also successfully used to reproduce experimental data.
Testing statics-dynamics equivalence at the spin-glass transition in three dimensions
Luis Antonio Fernandez,Victor Martin-Mayor
Physics , 2014, DOI: 10.1103/PhysRevB.91.174202
Abstract: The statics-dynamics correspondence in spin glasses relate non-equilibrium results on large samples (the experimental realm) with equilibrium quantities computed on small systems (the typical arena for theoretical computations). Here we employ statics-dynamics equivalence to study the Ising spin-glass critical behavior in three dimensions. By means of Monte Carlo simulation, we follow the growth of the coherence length (the size of the glassy domains), on lattices too large to be thermalized. Thanks to the large coherence lengths we reach, we are able to obtain accurate results in excellent agreement with the best available equilibrium computations. To do so, we need to clarify the several physical meanings of the dynamic exponent close to the critical temperature.
Pectinmethylesterase extraction from orange solid wastes: Optimization and comparison between conventional and ultrasound-assisted treatments  [PDF]
Antonio D. Rodriguez-Lopez, Luis Mayor, María M. Galfarsoro, Jorge Martinez-Otalo, Esperanza M. Garcia-Castello
Agricultural Sciences (AS) , 2013, DOI: 10.4236/as.2013.49B008
Abstract:

During orange juice production, a half of fresh oranges weight is considered as production waste (peels, pulp, seeds, orange leaves and damaged orange fruits). An alternative for the management of these wastes is their treatment by addition of lime and a latter pressing, obtaining a press cake and a press liquor rich in sugars (10° Brix) and citric acid, protein, pectin and ethanol. For non-thermal concentration of press liquor to obtain citruss molasses (65°-70° Brix), the removal of pectin is necessary. Traditionally, depectinization of juices has been done by using pectinmethylesterase (PME) enzymes from external sources. In this work it performed the extraction of PME enzymes from orange peels to obtain the optimum extraction conditions. Two different methods of solventextraction were compared (conventional andultrasound-assisted methods). For the conventional extraction experiments, a central composite design with three variables ([NaCl], pH and time) and five replicates of the center point was used. For ultrasound-assisted extraction, experiments were done at pH = 5.5 and [NaCl] = 1.25M), varying extraction time (1-30 min). Response variables were PME activity, protein content and a ratio between them, named PME effectiveness (ηPME). At the same experimental conditions (pH =5.5, [NaCl] = 1.25 M, t = 15 min) it was found that conventional extractions led to slightly better results in terms of ηPME than ultrasound-assisted extraction method.

Determinación por procedimientos físico-mecánicos de la dosificación de agua en morteros monocapa. Su incidencia en la aparición de patologías en la obra terminada
Mayor Lobo, Pablo Luis,Hernández Olivares, Francisco
Informes de la Construccion , 2007,
Abstract: Mortars coating for external facades often contain different additives mixed up in different proportions depending on the manufacturer, so that each mortar should be considered and treated as a composite displaying specific physical characteristics. This article aims to set up some ad hoc procedures that will allow determining the exact proportion of water added to a mortar. The methodology adopted will be based on a preliminary stage of sample- taking from the building site so that, given a defect in the product, it will be possible to detect defects in the mixture and also find out whether the manufacturera s specifications have been followed or not. It is shown that there exists a close relationship between the ultrasonic Younga s Modulus of each mortar and its surface cracked area after hydration. Los morteros de revestimiento monocapa tienen entre sus componentes diversos aditivos y adiciones en proporciones variables, según cada fabricante. De este modo, cada mortero monocapa puede calificarse como único. En este artículo se presentan una serie de procedimientos de laboratorio que permiten averiguar la cantidad de agua de amasado con la que se ha elaborado un mortero, partiendo de muestras extraídas en obra. De este modo, si aparece un defecto o anomalía del mortero aplicado puede descartarse, o no, que se deba a una incorrecta dosificación por no haber seguido las recomendaciones del fabricante. Se demuestra que la medida del Módulo de Young ultrasónico puede predecir la proporción de área fisurada que aparecerá en el mortero tras la hidratación de los conglomerantes.
Cobertura real de la ley de atención de emergencia y del Seguro Obligatorio contra Accidentes de Tránsito (SOAT)
Miranda,J. Jaime; Rosales-Mayor,Edmundo; Gianella,Camila; Paca-Palao,Ada; Luna,Diego; Lopez,Luis; Huicho,Luis; ,;
Revista Peruana de Medicina Experimental y Salud Pública , 2010, DOI: 10.1590/S1726-46342010000200004
Abstract: objective. the aim of this study was to ascertain, from patients’ perspective, the degree of knowledge and the actual coverage of the emergency health care law and the compulsory insurance against road traffic crashes (soat). material and methods. a cross-sectional, active surveillance of emergency wards of selected health facilities in three peruvian cities (lima, pucallpa y ayacucho) was conducted. results. out of 644 surveyed victims, 77% did not know about the law about provision of emergency health care (81% in lima, 64% in pucallpa y 93% in ayacucho; p<0,001). following the explanation of what this law entails, 46% reported to have received care according to the law specifications. as for soat, the health care related costs of 237 persons (37.2%) were not covered by any insurance scheme (74% in pucallpa, 34% in ayacucho and 26% in lima: p<0,001). conclusions. in this study, the lack of knowledge about the provision of emergency health care law was important, and the coverage of care was deficient as nearly half of participants reported not to be treated by one or more of the entitlements stated in such law. road traffic injuriesrelated health care costs were not covered by any insurance scheme in one of three victims. improvements on citizens’ information about their rights and of effective law enforcement are badly needed to reach a universal and more equitable coverage in the health care of road traffic-related victims.
Evaluación situacional, estructura, dinámica y monitoreo de los sistemas de información en accidentes de tránsito en el Perú - 2009
Miranda,J. Jaime; Paca-Palao,Ada; Najarro,Lizzete; Rosales-Mayor,Edmundo; Luna,Diego; Lopez,Luis; Huicho,Luis; ,;
Revista Peruana de Medicina Experimental y Salud Pública , 2010, DOI: 10.1590/S1726-46342010000200018
Abstract: objective: a baseline assessment of the structure, dynamics, and monitoring capabilities of the information systems for road traffic injuries was conducted in three peruvian cities: lima, huamanga and pucallpa. material and methods. 50 in-depth interviews were performed with key stakeholders, including managers and operators of information systems. the instrument was developed taking into account international standards and recommendations for information systems. results. six information systems were identified, some of which contain integrated operational systems enabling the recollection, processing, aggregation and data analysis following automated processes. these systems are considered valuable by different stakeholders because of their ability to present data in an organized manner. a low level of collaboration and exchange of information between institutions in the diverse aspects of data collection, processing and usage was observed. officially, formal collaboration agreements between institutions do exist, potentially enabling more collaborative work. an interest was expressed in establishing an integrated information system due to the need for detailed and solid/trusted information that maximizes the use of existing resources. conclusions. current information systems for road traffic injuries have limitations. the actual use and utility of the information for decision-making for prevention of road traffic injuries nationwide is limited.
Charity wins BRCA2 patent
Susan Mayor
Genome Biology , 2003, DOI: 10.1186/gb-spotlight-20040213-01
Abstract: The patent awarded by the European Patent Office covers all attempts to sequence the BRCA2 gene or to test for damaged or inactive variants. It will extend the access currently available to researchers in the UK, where the commercial subsidiary of Cancer Research UK (Cancer Research Technology Limited) already holds a patent on the gene. The charity suggested that it will significantly boost cancer research throughout the continent. Any laboratory wanting to investigate the gene would usually have to pay a license fee to the patent holder, but Cancer Research Technology has agreed in principle to waive the fees for all public laboratories that apply to it.Peter Rigby, chief executive of the Institute of Cancer Research in London, said: "This patent means that the discovery of the BRCA2 gene, which was made here at the Institute, will be freely available to our colleagues throughout Europe to research."The situation in Europe was previously complicated by the fact that a US biotechnology company, Myriad Genetics, had been awarded patents on the BRCA1 and BRCA2 genes that gave it rights to develop commercial laboratory testing services, diagnostic tests, and therapies based on the gene sequences. However, a UK patent was also held by Cancer Research Technology because much of the BRCA2 gene was first published by Mike Stratton's group at the Institute of Cancer Research, London, based on work funded by Cancer Research UK.Gert Matthijs, head of molecular diagnostics, University Hospital Leuven, Belgium, and a representative of the European Society of Human Genetics, said: "On behalf of the many European genetic diagnostic laboratories involved in the opposition procedures against the patents on the BRCA1 and BRCA2 genes owned by Myriad Genetics, we wish to express our strong appreciation to Cancer Research UK because they have chosen to offer royalty-free licenses on its patent on the BRCA2 gene to public health services in European countries.""This decision may contri
As biotecnologias no início dos anos noventa: êxitos, perspectivas e desafios
Mayor, Federico;
Estudos Avan?ados , 1992, DOI: 10.1590/S0103-40141992000300002
Abstract: biotechnologies consist in the use of living organisms, or parts of organisms, to make or modify products. these techniques have broad application in agriculture, biomedicine and food industry. recent progresses in cell and molecular biology originated a biotechmological revolution, here exemplified by genetic engineering. this paper discusses the economic impact of modern biotechnologies, stressing the bioindustry strategies, the problems of biosafety (mainly the release of genetically modified organisms into the environment) and the problems of patents originated by genetic engineering. the role of biotechnologies in developing countries is discussed. in these countries the biotechnologies represent new opportunities for economic and social development but, also, bring the risk of loosing comparative advantages.
LIDERES MUNDIALES DE LA BIOLOGíA DEL DESARROLLO SE REUNIERON EN SANTIAGO
ROBERTO MAYOR
Biological Research , 2001,
Abstract:
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