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Search Results: 1 - 10 of 9677 matches for " Lucy;Campos "
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Effect of lateralized epileptic discharges on the thought flow
Mendon?a, Paulo Bueno de;Piccinin, Lucy Campos;Capucho, Celso Medeiros;Campos, Carlos José Reis de;
Arquivos de Neuro-Psiquiatria , 2001, DOI: 10.1590/S0004-282X2001000300002
Abstract: purpose: pauses in verbal expression of thought flow in patients with partial epilepsy was studied in order to achieve a best comprehension of brain interhemispheric influences. method: we studied thirty nine patients with partial epileptic seizures and twenty four volunteers (control group). free association of ideas was used as a method to stablish the thought flow, starting with a stimulus word (subject name) that must be followed by spontaneous and consecutive word-phrase. patients were instructed to say any thought that came to their minds without any kind of censoring. subject responses were recorded through a pc keyboard and time intervals (pauses) between each word-phrase were processed by a software developed for this purpose. results: time intervals reduction among associations in right lesional group were compared to left lesional, right non-lesional and control groups. an increase of associative time intervals was observed in the right non-lesional group compared to left non-lesional group. conclusions: we suggest a possible inhibitory inter-hemispheric function of the right hemisphere modulating verbal expression of the thought flow. considering the hypothesis of the inter-hemispheric inhibition by the right hemisphere on left hemisphere, we admit that in epileptic patients with right hemispheric lesion there is an attenuation of the inter-hemispheric inhibition and an increase in thought flow, whereas in patients without a lesion but a paroxysmal epileptic activity in right temporal lobe there is an exacerbation of this inhibitory function and consequent reduction in the thought flow.
Effect of lateralized epileptic discharges on the thought flow
Mendon?a Paulo Bueno de,Piccinin Lucy Campos,Capucho Celso Medeiros,Campos Carlos José Reis de
Arquivos de Neuro-Psiquiatria , 2001,
Abstract: PURPOSE: Pauses in verbal expression of thought flow in patients with partial epilepsy was studied in order to achieve a best comprehension of brain interhemispheric influences. METHOD: We studied thirty nine patients with partial epileptic seizures and twenty four volunteers (control group). Free association of ideas was used as a method to stablish the thought flow, starting with a stimulus word (subject name) that must be followed by spontaneous and consecutive word-phrase. Patients were instructed to say any thought that came to their minds without any kind of censoring. Subject responses were recorded through a PC keyboard and time intervals (pauses) between each word-phrase were processed by a software developed for this purpose. RESULTS: Time intervals reduction among associations in right lesional group were compared to left lesional, right non-lesional and control groups. An increase of associative time intervals was observed in the right non-lesional group compared to left non-lesional group. CONCLUSIONS: We suggest a possible inhibitory inter-hemispheric function of the right hemisphere modulating verbal expression of the thought flow. Considering the hypothesis of the inter-hemispheric inhibition by the right hemisphere on left hemisphere, we admit that in epileptic patients with right hemispheric lesion there is an attenuation of the inter-hemispheric inhibition and an increase in thought flow, whereas in patients without a lesion but a paroxysmal epileptic activity in right temporal lobe there is an exacerbation of this inhibitory function and consequent reduction in the thought flow.
Essential Maternal and Newborn Care Skills Training for Midwives: Their Impact on Reducing Maternal and Neonatal Mortalities in Kenya  [PDF]
Lucy Gitonga
Open Journal of Obstetrics and Gynecology (OJOG) , 2016, DOI: 10.4236/ojog.2016.61009
Abstract: Continuing professional development (CPD) continues to gain acceptance as a model for health care professionals to engage in lifelong learning. Little is known about how CPD participants put the experience and the new knowledge into practice and whether it has impact on patient care outcomes. The primary objective of this study was to evaluate the effectiveness of CPD of Midwives on Essential Maternal and Newborn care skills on maternal and neonatal mortality in Embu County, Kenya. The study was an interventional non-randomized pretest post test study design of midwives from the participants of the 2010 ministry of health training on essential maternal and newborn care skills. Sixty (60) midwives working in maternity unit of Embu level five hospitals were targeted. The study was carried out in two phases. Phase one involved environmental scanning of the factors that support good performance in the workplace using a questionnaire. Phase two involved evaluation of the impact by testing a hypotheses using data collected by use of questionnaires, evaluation checklist and chart audit. Data were analyzed using qualitative content analysis and presented using percentages and frequency tables. Chi-square test and correlation analysis were used to show the association between variables, which are midwives essential maternal and newborn care skills and maternal and neonatal mortality. A chi-square χ2 = 14.143, df = 9 and a coefficient = 0.357. This coefficient is less than p-value at Alpha 0.05 and therefore is not significant, proving that the essential maternal and neonatal care skills do not contribute to reduction in mortalities as such two variables are almost independent of each other, whether one exists does not necessitate the existence of another nor does it reduce maternal and neonatal mortalities in Kenya.
Influence of the polymorphism of apolipoprotein E in cerebral vascular disease
Souza Dorotéia R.S.,Campos Bernadete F.,Arruda érika F. de,Yamamoto Lucy J.
Arquivos de Neuro-Psiquiatria , 2003,
Abstract:
Role of sphingosine kinases and sphingosine 1-phosphate in mediating adipogenesis  [PDF]
Lucy D. Mastrandrea
Journal of Diabetes Mellitus (JDM) , 2013, DOI: 10.4236/jdm.2013.32009
Abstract:

Recent Background: Development of obesity involves promotion of preadipocyte differrentiation. This study investigated the role that sphingosine kinases (SPHK) and ceramide-derived sphingosine 1-phosphate (S1P) play in adipocyte terminal differentiation. Materials and Methods: The mouse 3T3-L1 cell line was used as a model for adipogenesis. Cells were harvested at specific time points after initation of differentiation, and SPHK activity was measured. 3T3-L1 cells were treated with S1P and expression of early adipogenesis transcription markers was measured by real time PCR. The expression of S1P-receptors (S1PRs) during differentiation was measured. Results: SPHK activity is induced when 3T3-L1 cells are treated with insulin, dexamethasone, and isobutylmethylxanthine to induce differentiation. SPHK1 is active in preadipocytes and early in the differentiation process. Both SPHK1 and SPHK2 isozymes contribute to activity in differentiated adipocytes. Inhibition of SPHK1 attenuates adipocyte differentiation; however, extracellular S1P does not rescue the effect of SPHK1 inhibition on adipogenesis. Although treatment of preadipocytes with S1P induced message expression of the early adipogenesis transcription factor CC AAT/ binding proteinalpha, continued treatment did not fully support the development of differentiated adipocytes. Sphingosine 1-phosphate receptors (S1PRs) are expressed in preadipocytes and message expression declines markedly during adipocyte differentiation. Conclusion: These results demonstrate that the contribution of SPHK and S1P to adipogenesis is mediated primarily through biphasic activation of SPHK1 and 2 with extracellular S1P and S1PRs playing little role during preadipocyte differentiation.

Modeling of Soft Tissues Interacting with Fluid (Blood or Air) Using the Immersed Finite Element Method  [PDF]
Lucy T. Zhang
Journal of Biomedical Science and Engineering (JBiSE) , 2014, DOI: 10.4236/jbise.2014.73018
Abstract:

This paper presents some biomedical applications that involve fluid-structure interactions which are simulated using the Immersed Finite Element Method (IFEM). Here, we first review the original and enhanced IFEM methods that are suitable to model incompressible or compressible fluid that can have densities that are significantly lower than the solid, such as air. Then, three biomedical applications are studied using the IFEM. Each of the applications may require a specific set of IFEM formulation for its respective numerical stability and accuracy due to the disparities between the fluid and the solid. We show that these biomedical applications require a fully-coupled and stable numerical technique in order to produce meaningful results.

Perceptions and Use of Herbal Remedies among Patients with Diabetes Mellitus in Murang’a North District, Kenya  [PDF]
Joshua Mwangi, Lucy Gitonga
Open Journal of Clinical Diagnostics (OJCD) , 2014, DOI: 10.4236/ojcd.2014.43024
Abstract: Diabetes mellitus is a chronic disease with a world wide distribution. Use of herbal remedies has been on increase with World Health Organization estimating that 80 percent of the world’s population presently uses some form of herbal medicine for some aspect of primary health care. Objectives of this study were therefore to determine the perceptions people with diabetes mellitus have towards herbal remedies, to determine the extent to which they use herbal remedies and also to establish whether there is any association between the perceptions people have on herbal remedies and use of herbal remedies. The study was carried out in Murang’a District, in Mathioya and Kangema Constituencies where five community health units were purposively selected to participate in the study based on their level of establishment in community health strategy. Data was collected using interview schedules. SPSS was used for data analysis. Significant findings from this study were: a significant number of the respondents (15%) were diagnosed with diabetes mellitus when already admitted in the wards prior to which period they had no idea that they were diabetic, over 86% of those interviewed were given information on diabetes management on diagnosis and they attend hospital clinics for follow-up regularly and therefore this means that the reason for seeking alternative modes of treatment is not due to lack of information on diabetes but due to other reasons, 12.4% of those interviewed admitted using herbal remedies as part of their management of diabetes. Recommendations made following the study were: the government of Kenya through Ministry of Health should encourage rigorous screening of clients and population in general for diabetes to ensure diabetes is diagnosed early and put under appropriate management and that the government of Kenya through Ministry of Health should put up a campaign educating diabetic patients on the potential dangers associated with combining herbal remedies with contemporary medicines due to their interactions.
Remote Sensing Study of Glacial Change in the Northern Patagonian Icefield  [PDF]
Lucy Dixon, Shrinidhi Ambinakudige
Advances in Remote Sensing (ARS) , 2015, DOI: 10.4236/ars.2015.44022
Abstract: The Patagonian Icefield has the largest temperate ice mass in the southern hemisphere. Using remote sensing techniques, this study analyzed multi-decadal glacial retreat and expansion of glacier lakes in Northern Patagonia. Glacial boundaries and glacier lake boundaries for 1979, 1985, 2000, and 2013 were delineated from Chilean topographic maps and Landsat satellite images. Aster stereo images were used to measure mass balance from 2007 to 2012. The highest retreat was observed in San Quintin glacier. The area of glacier lakes increased from 13.49 km2 in 1979 to 65.06 km2 in 2013. Four new glacier lakes formed between 1979 and 2013. Between 2007 and 2012, significant glacial thinning was observed in major glaciers, including HPN1, Pared Norte, Strindberg, Acodado, Nef, San Quintin, Colonia, HPN4, and Benito glaciers. Generally, ablation zones lost more mass than accumulation zones.
Adolescents’ Compulsive Internet Use and Depression: A Longitudinal Study  [PDF]
Einar B. Thorsteinsson, Lucy Davey
Open Journal of Depression (OJD) , 2014, DOI: 10.4236/ojd.2014.31005
Abstract: Background: The present longitudinal study examined predictors of compulsive internet use and depression. Method: Adolescents, 21 males and 20 females, completed online questionnaires with a 12-month interval. Results: Social internet use (i.e., using instant messaging and social networks) was associated with decreased levels of depression. High support satisfaction, use of social networking, and instant messaging contributed to lower changes in compulsive Internet use. Conclusion: The effects of social internet use in combination with different psychosocial factors seem to have more positive effects than negative ones on change in depression and the development of compulsive internet use.

Perspectives of Continuing Professional Development (CPD) for Kenyan Midwives  [PDF]
Lucy Gitonga, Njogu Samson Muriuki
Open Journal of Clinical Diagnostics (OJCD) , 2014, DOI: 10.4236/ojcd.2014.42015
Abstract: Continuing Professional Development (CPD) provides an important strategy for reduction of maternal morbidity and mortality with the aim of attaining Millennium Development goals (MDG) four and five. However, there is lack of information about how Kenyan midwives understand and perceive CPD and how this is situated in the practice and social context. This research aimed to explore Kenyan midwives’ experience and perceptions of CPD. A descriptive explorative approach gathered focus group discussion and questionnaire data on beliefs, opinions, and perceptions, demotivating and motivating factors to CPD of a total of 25 midwives in a level five hospital in Kenya. Questionnaires were piloted and self-administered after cleaning and focus groups taped and transcribed verbatim. Data were analyzed thematically using inductive approach with the aid of SPSS computer program. Results: Four key themes emerged from the data: Midwives’ views of CPD, their motivators for undertaking CPD, the choices they made around CPD, their demotivators for undertaking CPD. Congruence with the issues evident in the literature were: the difficulties with role diversity, the importance of CPD in personal and professional growth, the importance of flexible modes of study and the importance of a supportive culture for ongoing learning. The study findings helped in identifying gaps in the literature about Kenyan midwives’ perspectives on CPD.
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