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Search Results: 1 - 10 of 398922 matches for " Luís David; "
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Inefetividade e ineficiência: reflex?es sobre a epidemiologia e os servi?os de saúde de um estado de mal-estar social
Castiel, Luís David;
Cadernos de Saúde Pública , 1990, DOI: 10.1590/S0102-311X1990000100004
Abstract: a discussion about effectiveness of epidemiological practice im public health services in brazil is presented. in addition, an approach towards theoretical frames concerning epidemiology's object is developed regarding ''social" and "classical" trends. finally, it is emphasized the importance of ideological dimensions in devising the "subject of epidemiology" and its relationship with public health services effectiveness.
Freud: um epidemiologista?
Castiel, Luís David;
Cadernos de Saúde Pública , 1988, DOI: 10.1590/S0102-311X1988000300006
Abstract: an approach to freud's causal thinking concerning the origins of hysteria is presented. it is used john stuart mill's canons from his "sistem of logic". even without empirical evidence, freud' s thinking can be regarded through mill's logic to devise causal hypotheses in epidemiologic research.
For?a e vontade: aspectos teórico-metodológicos do risco em epidemiologia e preven??o do HIV/AIDS
Castiel,Luís David;
Revista de Saúde Pública , 1996, DOI: 10.1590/S0034-89101996000100012
Abstract: health education related to hiv/aids prevention is approached from the standpoint of risk in epidemiology. the shortcomings of the outcomes of health programs, in terms of controlling the spread of the disease led the author to consider the premisses that lie behind these programs. one of them is the idea of the rationality of the "receiver" of health information. notions related to public understanding of concepts produced by epidemiology are considered. some limitations of epidemiological methods regarding interactive relationships in processes of being affected by aids are discussed. a method that deals with interactional aspects is presented.
For a e vontade: aspectos teórico-metodológicos do risco em epidemiologia e preven o do HIV/AIDS
Castiel Luís David
Revista de Saúde Pública , 1996,
Abstract: Aborda-se, sob o ponto de vista do risco em epidemiologia, as propostas de educa o em saúde com vistas à preven o do HIV/AIDS. Levando em conta os resultados insatisfatórios dos programas de educa o sanitária, baseados no conceito de risco visando ao controle da pandemia, discutem-se as possíveis premissas subjacentes às referidas propostas. Nelas, se destaca a concep o de racionalidade do receptor de tais conteúdos educacionais. Assim, ficam consideradas as no es que envolvem o entendimento público dos conceitos epidemiológicos. S o discutidas limita es do instrumental epidemiológico para dar conta das dimens es interativas no adoecimento pela AIDS. Apresenta-se uma abordagem que procura levar em considera o tais aspectos.
Ariadne, Dédalo e os bondes do tigr o
Castiel Luís David
Cadernos de Saúde Pública , 2001,
Toward a neurobiology of auditory object perception: What can we learn from the songbird forebrain?
Kai LU, David S. VICARIO
Current Zoology , 2011,
Abstract: In the acoustic world, no sounds occur entirely in isolation; they always reach the ears in combination with other sounds. How any given sound is discriminated and perceived as an independent auditory object is a challenging question in neuroscience. Although our knowledge of neural processing in the auditory pathway has expanded over the years, no good theory exists to explain how perception of auditory objects is achieved. A growing body of evidence suggests that the selectivity of neurons in the auditory forebrain is under dynamic modulation, and this plasticity may contribute to auditory object perception. We propose that stimulus-specific adaptation in the auditory forebrain of the songbird (and perhaps in other systems) may play an important role in modulating sensitivity in a way that aids discrimination, and thus can potentially contribute to auditory object perception [Current Zoology 57 (6): 671–683, 2011].
Genomic Instability Is Associated with Natural Life Span Variation in Saccharomyces cerevisiae
Hong Qin, Meng Lu, David S. Goldfarb
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002670
Abstract: Increasing genomic instability is associated with aging in eukaryotes, but the connection between genomic instability and natural variation in life span is unknown. We have quantified chronological life span and loss-of-heterozygosity (LOH) in 11 natural isolates of Saccharomyces cerevisiae. We show that genomic instability increases and mitotic asymmetry breaks down during chronological aging. The age-dependent increase of genomic instability generally lags behind the drop of viability and this delay accounts for ~50% of the observed natural variation of replicative life span in these yeast isolates. We conclude that the abilities of yeast strains to tolerate genomic instability co-vary with their replicative life spans. To the best of our knowledge, this is the first quantitative evidence that demonstrates a link between genomic instability and natural variation in life span.
The reactance wave diffraction problem by a strip in a scale of Bessel potential spaces
Luís P. Castro,David Natroshvili
Opuscula Mathematica , 2006,
Abstract: We consider a boundary-transmission problem for the Helmholtz equation, in a Bessel potential space setting, which arises within the context of wave diffraction theory. The boundary under consideration consists of a strip, and certain reactance conditions are assumed on it. Operator theoretical methods are used to deal with the problem and, as a consequence, several convolution type operators are constructed and associated to the problem. At the end, the well-posedness of the problem is shown for a range of regularity orders of the Bessel potential spaces, and for a set of possible reactance numbers (dependent on the wave number).
Response Properties of the Auditory Telencephalon in Songbirds Change with Recent Experience and Season
Thomas A. Terleph, Kai Lu, David S. Vicario
PLOS ONE , 2008, DOI: 10.1371/journal.pone.0002854
Abstract: The caudomedial nidopallium (NCM) is a telencephalic auditory area that is selectively activated by conspecific vocalizations in zebra finches and canaries. We recently demonstrated that temporal and spectral dynamics of auditory tuning in NCM differ between these species [1]. In order to determine whether these differences reflect recent experience, we exposed separate groups of each species and sex to different housing conditions. Adult birds were housed either in an aviary with conspecifics (NORM), with heterospecifics (canary subjects in a zebra finch aviary, and vice versa: (CROSS)), or in isolation (ISO) for 9 days prior to testing. We then recorded extracellular multi-unit electrophysiological responses to simple pure tone stimuli (250–5000 Hz) in awake birds from each group and analyzed auditory tuning width using methods from our earlier studies. Relative to NORM birds, tuning was narrower in CROSS birds, and wider in ISO birds. The trend was greater in canaries, especially females. The date of recording was also included as a covariate in ANCOVAs that analyzed a larger set of the canary data, including data from birds tested outside of the breeding season, and treated housing condition and sex as independent variables. These tests show that tuning width was narrower early in the year and broader later. This effect was most pronounced in CROSS males. The degree of the short-term neural plasticity described here differs across sexes and species, and may reflect differences in NCM's anatomical and functional organization related to species differences in song characteristics, adult plasticity and/or social factors. More generally, NCM tuning is labile and may be modulated by recent experience to reflect the auditory processing required for behavioral adaptation to the current acoustic, social or seasonal context.
Planejamento em Saúde e Epidemiologia no Brasil: casamento ou divórcio?
Castiel, Luís David;Rivera, Francisco Javier Uribe;
Cadernos de Saúde Pública , 1985, DOI: 10.1590/S0102-311X1985000400005
Abstract: this paper discusses the relationship between the epidemiological tool and the planning methods applied to public health activities in brazil in order to achieve this, current ideas and trends of these disciplines are briefly reviewed. an analytical framework related to rationality in the planning process is considered. at last, possible reasons for explaining health planning failure in brazil and the role of epidemiology within this context are presented.
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