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Search Results: 1 - 10 of 359039 matches for " Luís Cesar;Matos "
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Relationship between peripheral and mesenteric serum levels of CEA and CA 242 with staging and histopathological variables in colorectal adenocarcinoma
Cardoso, Mauro Lamelas;Fernandes, Luís Cesar;Kim, Su Bong;Matos, Delcio;
Acta Cirurgica Brasileira , 2009, DOI: 10.1590/S0102-86502009000500012
Abstract: purpose: to compare histopathological variables and staging in colorectal adenocarcinoma cases with cea and ca 242 in peripheral and mesenteric blood. methods: in 169 individuals underwent surgery for colorectal cancer, cea and ca 242 were analyzed and compared to mesenteric and peripheral blood and correlated with macroscopic tumor's morphology and size, degree of cell differentiation, venous, neural and lymphatic involvement and tnm classification. results: there was a difference between the mesenteric (m) and peripheral (p) serum levels of cea (p=0.020). higher levels of markers were correlated with venous invasion cea (p) p=0.013, cea (m) p=0.05, ca 242 (m) p=0.005 and ca 242 (p) p=0.038; with advanced staging cea (p) < cea (m) (p < 0.05); ca 242 (p) < ca 242 (m) (p < 0.05); and with greater dimensions cea (p) < cea (m) (p < 0.001); ca 242 (p) < ca 242 (m) (p < 0.001). ca 242 became higher with neural invasion (p): p=0.014, (m): p=0.003). conclusions: there were higher mesenteric than peripheral levels of cea. both mesenteric and peripheral levels of cea and ca 242 were higher in neoplasm with venous involvement, greater diameter and advanced stages. there was a correlation between ca 242 and neural invasion.
Randomized clinical trial comparing spinal anesthesia with local anesthesia with sedation for loop colostomy closure
Abreu, Rone Ant?nio Alves de;Vaz, Filinto Anibal Alagia;Laurino, Ricardo;Speranzini, Manlio Basilio;Fernandes, Luís Cesar;Matos, Delcio;
Arquivos de Gastroenterologia , 2010, DOI: 10.1590/S0004-28032010000300011
Abstract: context: recent studies have shown that local anesthesia for loop colostomy closure is as safe as spinal anesthesia for this procedure. objectives: randomized clinical trial to compare the results from these two techniques. methods: fifty patients were randomized for loop colostomy closure using spinal anesthesia (n = 25) and using local anesthesia (n = 25). preoperatively, the bowel was evaluated by means of colonoscopy, and bowel preparation was performed with 10% oral mannitol solution and physiological saline solution for lavage through the distal colostomy orifice. all patients were given prophylactic antibiotics (cefoxitin). pain, analgesia, reestablishment of peristaltism or peristalsis, diet reintroduction, length of hospitalization and rehospitalization were analyzed postoperatively. results: surgery duration and local complications were greater in the spinal anesthesia group. conversion to general anesthesia occurred only with spinal anesthesia. there was no difference in intraoperative pain between the groups, but postoperative pain, reestablishment of peristaltism or peristalsis, diet reintroduction and length of hospitalization were lower with local anesthesia. conclusions: local anesthesia plus sedation offers a safer and more effective method than spinal anesthesia for loop colostomy closure.
Cost-effectiveness analysis on spinal anesthesia versus local anesthesia plus sedation for loop colostomy closure
Vaz, Filinto Aníbal Alagia;Abreu, Rone Ant?nio Alves;Soárez, Patrícia Coelho de;Speranzini, Manlio Basílio;Fernandes, Luís Cesar;Matos, Delcio;
Arquivos de Gastroenterologia , 2010, DOI: 10.1590/S0004-28032010000200008
Abstract: context: studies in the area of health economics are still poorly explored and it is known that the cost savings in this area is becoming more necessary, provided that strict criteria. objective: to perform a cost-effectiveness analysis of spinal anesthesia versus local anesthesia plus sedation for loop colostomy closure. methods: this was a randomized clinical trial with 50 patients undergoing loop colostomy closure either under spinal anesthesia (n = 25) or under local anesthesia plus sedation (n = 25). the duration of the operation, time spent in the post-anesthesia recovery room, pain, postoperative complications, length of hospital stay, laboratory and imaging examinations and need for rehospitalization and reoperation were analyzed. the direct medical costs were analyzed. a decision tree model was constructed. the outcome measures were mean cost and cost per local and systemic postoperative complications avoided. incremental cost-effectiveness ratios were presented. results: duration of operation: 146 ± 111.5 min. vs 105 ± 23.6 min. (p = 0.012); mean time spent in post-anesthesia recovery room: 145 ± 110.8 min. vs 36.8 ± 34.6 min. (p<0.001). immediate postoperative pain was lower with local anesthesia plus sedation (p<0.05). local and systemic complications were fewer with local anesthesia plus sedation (p = 0.209). hospitalization + rehospitalization: 4.5 ± 4.1 days vs 2.9 ± 2.2 days (p<0.0001); mean spending per patient: r$ 5,038.05 vs 2,665.57 (p<0.001). incremental cost-effectiveness ratio: r$ -474.78, indicating that the strategy with local anesthesia plus sedation is cost saving. conclusion: in the present investigation, loop colostomy closure under local anesthesia plus sedation was effective and appeared to be a dominant strategy, compared with the same surgical procedure under spinal anesthesia.
Political Parties: Old Concepts and New Challenges
Luís Salgado de Matos
Análise Social , 2005,
Debaixo de Fogo! Salazar e as For as Armadas (1935-1941)
Luís Salgado de Matos
Análise Social , 2004,
Representa o Política Textos Clássicos
Luís Salgado de Matos
Análise Social , 2010,
Homens em Fundo Azul-Marinho. Ensaio de Observa o Sociológica sobre Uma Corpora o nos Meados do Século XX: a Armada Portuguesa
Luís Salgado de Matos
Análise Social , 2004,
DNA damage levels in systemic lupus erythematosus patients with low disease activity: An evaluation by comet assay  [PDF]
Thaís Muniz Montalv?o, Ana Luisa Miranda-Vilela, Mariana Matos Roll, Cesar Koppe Grisolia, Leopoldo Santos-Neto
Advances in Bioscience and Biotechnology (ABB) , 2012, DOI: 10.4236/abb.2012.327121
Abstract: Oxidative stress has been implicated in the inflammatory process of Systemic Lupus Erythematosus (SLE), particularly by the formation of anti-DNA autoantibodies, which can lead to DNA damage. The aim of this study was to investigate, through comet assay, whether the level of DNA damage in SLE patients is different from that of healthy subjects. Twenty-five adult SLE patients with SLEDAI up to ten, and 25 healthy subjects were paired according to age, gender and Body Mass Index (BMI). Other anthropometric variables were also assessed. Comet assay was assessed as the marker of oxidative stress described as DNA Damage (DD) percentage. Waist Circumference (WC), Hip Circumference (HC) and BMI were also performed. Exclusion criteria for patients and controls comprised smoking and other chronic disorders. Level of damage index was remarkably higher in SLE patients than in controls, and no significant differences between the groups were found for age, BMI, WC and HC. No stratification concerning gender was performed, since there were just two males per group. No correlation was observed between BMI and DD (%). DD increased in SLE, which reflects the oxidant/antioxidant imbalance in these patients. These findings support an association between oxidative stress and SLE. This stronger correlation observed in patients with low disease activity may be useful in elucidating the mechanisms of disease pathogenesis.
Marcadores tumorais no cancer colorretal
Fernandes, Luís César;Matos, Delcio;
Revista do Colégio Brasileiro de Cirurgi?es , 2002, DOI: 10.1590/S0100-69912002000200009
Abstract: colorectal cancer is a clinical entity of a persistent relevance in clinical practice and its early diagnosis is a determinant factor to obtain better therapeutic results. tumor markers are helpful means for a better approach to individuals with such neoplasm. in the present review, the authors analyze the phases in which surgical-clinical treatment markers must be used: diagnosis, determination of tumor stage, establishment of prognosis and detection of recurrence. current and future markers and the consensus on their use are discussed. causal factors for errors in diagnosis with markers and perspectives of use are also presented.
Sexual Education in Schools in Portugal: Evaluation of a 3 Years Period  [PDF]
Margarida Gaspar de Matos, Marta Reis, Lúcia Ramiro, José Luís Pais Ribeiro, Isabel Leal
Creative Education (CE) , 2014, DOI: 10.4236/ce.2014.515154

Sexual education is crucial for reducing sexual risk behaviors (or at least not to enable their increase). The goal of this study was to evaluate the implementation of sexual education in schools. For the quantitative study, all schools (clustered in Schools Organic Units—SOUs) in mainland Portugal were invited to participate. Study 1—A total of 428 school principals, 424 coordinating teachers of health education, belonging to 428 Organic Units (OU), which correspond to 53% of the Portuguese public SOU, corresponding to 617,701 students and 60,595 teachers participated in the quantitative study. Study 2—For the qualitative study, interviews were conducted. Analysis of the results of both studies emphasized that Law n.° 60/2009 (6th August) is being fulfilled with regard to the implementation of sexual education as well as the number of hours established for its implementation. In general the SOUs organized an office that provides information and support for students and manages its functioning. The implementation of the Law is, overall, ranked as good/very good (83.7%). However, during the qualitative study, school principals and teachers emphasize that SOUs are making a huge effort to implement the Law, some of them questioning their ability to continue this process due to the present conditions. Principals and teachers reported the need to “revitalize” this area, underlining the need to maintain the Law and one annual “Call” from which the Ministry of Education and Science receives proposals for funding schools for projects in the area of health promotion, and teacher training.

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