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Search Results: 1 - 10 of 36106 matches for " Lorena Menéndez "
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Time to Progression of AFP (TPA) as a Predictor of Survival in Hepatocellular Carcinoma Treated with Sorafenib (SOR)  [PDF]
Maria Varela, Olegario Casta?o-Fernández, Marcelo Garrido, Lorena Blanco-García, Pablo Martínez-Camblor, Alicia Mesa-álvarez, Carmen Navascués, Valle Cadahía-Rodrigo, Rafael Menéndez de Llano, Ramon Pérez-álvarez, Maria Luisa González-Diéguez, Manuel Rodríguez
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.514133
Abstract: Background: The standard therapy in advanced hepatocellular carcinoma (HCC) is sorafenib (SOR), which has the inconvenience of toxicity and discontinuation. Patient selection and the use of early markers are critical for optimizing the potential benefit of SOR. Alpha-fetoprotein (AFP) has an established role in HCC prognosis. The objective was to evaluate whether AFP variation during SOR treatment reflects the lack of progression to SOR and can be used as a prognostic factor. Methods: AFP levels were prospectively analyzed in 114 patients to determine whether the time to progression of AFP (TPA) at 3 months had a prognostic value for survival. Results: Between July 2007 and October 2012, 114 patients were included (mean age 64 years, 97 male, 96 with cirrhosis). Etiology was alcohol 47 (41%) and hepatitis C virus (HCV) 31 (27%). According to the Barcelona Clinic Liver Cancer (BCLC) staging system: A (one case), B (24 cases) and C (89 cases). The Child-Pugh was Class A in 89 cases. The general condition of the patient according to ECOG-PS was 0 in 73 cases. The median duration of treatment was 5 months (3.47 - 6.53, 95% CI). The median overall survival (OS) was 9.23 months. The standard dose was maintained in 26 patients (22.8%). Sixty-seven percent of patients experienced at least one adverse event grade 3-4. The time to progression of AFP lower or higher than 3 months was an independent prognostic factor of OS (univariate and multivariate analysis): 8.10 vs. 18.85 months, P < 0.001. Conclusion: HCC treated with SOR with TPA > 3 months had longer OS, and TPA was an independent prognostic factor.
Associated or Concomitant Diseases Influence Significantly the Health-Sickness Concept in Celiacs  [PDF]
Eduardo Cueto Rúa, Maria Teresita Gonzalez Villar, Ricardo Wright, Claudia Losada Gómez, Karol Martínez, María Arregui, Luciana Guzmán, Cecilia Zubiri, Viviana Bernedo, Anabella Zosi, Lorena Menéndez, Lucas Ruiz, Leopoldo Mancinelli, María Urrutia, Ricardo Drut
Open Journal of Epidemiology (OJEpi) , 2017, DOI: 10.4236/ojepi.2017.72013
Abstract: It is well-known that feeling to be a healthy or sick person most probably results from the mind than from the body. We all know healthy people who feel sick and vice versa. We were interested in the health and sickness feeling of celiac people, their autorating of these feelings and its conditioning factors as well as their expectations. In this paper we present the results of an inquiry to evaluate these situations. We performed a descriptive, transversal and prospective study for 2 years to groups of celiacs and their families. They received a closed inquiry to be completed before the beginning of the talk. The inquiry included personal data and the co-existence of associated or concomitant (AoC) diseases. Most of the sample’s patients felt to be a healthy person (86.8%). Mothers see their children as healthy and the auto rated criteria is significantly better than the adult celiac person (“t”= -6.024 (p = 0.000)). AoC diseases influenced negatively in the feeling of being healthy and strongly decreased the autorating. Longer time passed on treatment reflects an increase feeling of health and of the autorating. In people with AoC diseases and who feel sick, the increased time of treatment did not show significant differences. People with “gluten sensitivity” felt sicker and auto rated themselves with a lower number than celiacs. Many pediatric gastroenterologists notice that the newly agreed definition of celiac disease, referring it as “autoimmune, chronic, incurable, and multisystemic”, results in a very negative character of the condition which might compromise the future labour of this people as well as their admittance to different health insurance systems.
Newspapers Coverage of Spain and the United States: A Comparative Analysis  [PDF]
Antonio V. Menéndez Alarcón
Sociology Mind (SM) , 2012, DOI: 10.4236/sm.2012.21009
Abstract: This article assesses the content of foreign news coverage in the United States and Spain. It draws on content analysis of two U.S. and two Spanish newspapers over a 28-month period, during 2005-2007 and in 2009. The results show that the content of these newspapers tends to be more negative when covering politics. However, there was a major change in the type of coverage in the Spanish newspapers from the period 2005-2007 to 2009. Coverage of U.S. politics in 2009 was much more positive than in the previous period studied. These findings suggest that newspapers contribute to an overall unfavorable representation of these countries for their respective populations. Also, when covering international news, newspapers are less independent from their government agendas than they claim; supporting critical research findings that mainstream media is vulnerable to “news management” by the government.
Las tecnologías apropiadas de la salud: una aproximación del enfoque Ciencia- Tecnología- Sociedad al tema
Menéndez Laria,Aimeé;
Humanidades M??dicas , 2006,
Abstract: health situation in contemporary world demands to society to place in a firth level of analysis questions like justness, promotion and prevention of health, quality of the attention, the ethical dilemmas, the recognition of the technological necessities of health in the national policy as an important factor for its development, and the use of proper technologies. for this reason of the most up-to-date literature in the last aspect, is made, with the purpose of contributing to the knowledge and broadcasting of a controversial but effective topic
Metodología cualitativa: varios problemas y reiteradas omisiones
Menéndez,Eduardo L.;
Index de Enfermería , 2012, DOI: 10.4321/S1132-12962012000100014
Abstract: from recognize the important contributions of the approaches and qualitative techniques to the study and intervention on health/illness/attention-prevention processes, this article drew and analyzes the domain of certain guidelines which have a negative impact or, at least, generated certain biases in quality production, which tend to exclude substantive aspects of the studied reality. the main analyzed here are as follows: a) the denial or, at least, a reluctance to make hypothesis, including interpretative ones; b) tendency to simplify increasingly qualitative techniques; c) the limited use of one of the main qualitative techniques, as in the case of observation, although participant observation is usually mentioned; d) trend strong to work almost exclusively with the social representations, discourses, narratives and/or experiences, leaving aside practices or assuming that the representations are equivalent to practices.
Magallania (Punta Arenas) , 2010, DOI: 10.4067/S0718-22442010000200007
Abstract: the aim of this paper is to contribute, from a bioarchaeological perspective, to the discussion about the model of economic intensification and diet broadening of hunter-gatherer populations in northeastern patagonia previously proposed by different authors. the underlying presuposition is that such process would have detectable effects in the intra-and interpopulational distribution of health and oral function indicators. to test this proposition, we analyzed temporal trends in the prevalence of different dental and periodontal relevant indicators (caries, abscesses and loss of antemortem teeth, periodontitis, tilting and lipping) in a collection formed by three diachronic subsamples of skulls from the río negro valley covering the last 3.600 years ab 14c. the results show that the prevalence of caries, periodontal disease and lipping tend to increase over time, while those of antemortem tooth loss, abscesses and tilting decrease. taken together, these temporal trends are consistent with the hypothesis of increased consumption of plant resources, particularly those with cariogenic potential (i.e. high starches content), after 1.000 ab.
Modelos de atención de los padecimientos: de exclusiones teóricas y articulaciones prácticas
Menéndez,Eduardo L.;
Ciência & Saúde Coletiva , 2003, DOI: 10.1590/S1413-81232003000100014
Abstract: in many latin american societies - especially in mexico - there is a diversity of care illness models, which are considered in an isolated and even antagonistic way by state health sector. this happens by living out the observation of individual and group practices which shows the narrow and continual relationship between this models. this paper describes particular relations between biomedicine and selfcare to show the constant transaction process between them. in first place some basic biomedical and selfcare characteristics are considered, then we observe the transaction between them with special attention to drugs prescription and selfmedication. transaction process is usually ignored by biomedicine and selfmedication process specially criticised by it. we are in the presence of a paradox because biomedicine and state health sector constantly promotes selfcare process which involves selfmedication. we notice that this takes place without a reflection on articulation and consequences of this transactions on health/illness/care process. we propose to think about this process in view of its intentional use by health services.
Las influenzas por todos tan temidas o de los difíciles usos del conocimiento
Menéndez, Eduardo L.;
Desacatos , 2010,
Abstract: this study describes and analyzes information generated by mexican national newspapers and journals specialized on public health concerning the possibly epidemic "avian influenza" that occurred by the end of 2005 and the beginning of 2006. for this episode, we observe multiple similarities with the april - june 2009 outbreak of influenza a (h1n1). our research seeks to reveal that the scaremongering that characterized how the media managed this situation is not only a media-related outcome, but a correlate of that observed in health institutions as well as the response of their officials and members of scientific and technical disciplines. this scaremongering is the product derived from multiple factors, including economic and political interests of several social sectors; notwithstanding, it results mainly from the wavering between uncertainty and the need of intervention that characterizes actions of the health sector, when it has to deal with possible but imprecise situations of collective risk.
Epidemiología sociocultural: propuestas y posibilidades
Menéndez, Eduardo L.;
Región y sociedad , 2008,
Abstract: this article contains a description and analysis of divergence, convergence and complementation processes between epidemiology and medical anthropology, with the purpose of contributing to the development of sociocultural epidemiology in mexico. particular issues are analyzed concerning problems with linking both disciplines, and which allude to the possibility of establishing generalizations, notions of prevention, validity and reliability of qualitative and statistical data, and criteria for informant selection, points which are discussed in terms of epidemiological and socio-anthropological approaches to poverty, gender, racism or alcohol consumption in the health/disease/care process. divergent and convergent issues are analyzed for all these topics, which does not negate a strong trend toward polarization between both disciplines. even so, we consider that this can be reduced and surmounted through strategies aimed at developing a sociocultural epidemiology conceived not as a discipline but as a link between epidemiological and anthropological approaches. one of the main strategies is a reflection on the health process under study, which includes an in-depth discussion of the researchers' own theoretical, empirical and technical assumptions.
Veinte a?os de la Reforma Psiquiatríca: Panorama del estado de la psiquiatría en Espa?a de los a?os 1970 a los 2000: de un pensamiento único a otro
Menéndez Osorio,Federico;
Revista de la Asociación Espa?ola de Neuropsiquiatría , 2005, DOI: 10.4321/S0211-57352005000300005
Abstract: 20 years after the psychiatric reformation, the situation of psychiatry in spain is analysed from the seventies to the two thousands, taking as a frame the report of the ministerial committee for the psychiatric reformation. succintly, it is divided in three periods going from the psychiatry during the latest years of the dictatorship, through the implications of the model and changes introduced by the psychiatric reformation, to the field appearing as dominant in the panorama of the psychiatric practice from the nineties: the neurosciences. it could be very brie?y expressed with a sentence: from an unique thought to another one. the prevailing epistemic basis and paradigms are outlined, as well as the characteristics and forms of expression of this unique thought, and the potential risks of totalitarian temptations, scientific and ideological fundamentalisms, restricting the diversity and freedom of thinking and the scientific progress at all.
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