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Search Results: 1 - 10 of 27530 matches for " Lisong Hu "
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Physicochemical Properties and Nutritional Ingredients of Kernel Oil of Carya cathayensis Sarg  [PDF]
Lisong Hu, Menghao Du, Jingping Zhang
American Journal of Plant Sciences (AJPS) , 2018, DOI: 10.4236/ajps.2018.912180
Abstract: Carya cathayensis Sarg is distributed near Tianmu mountain areas in Zhejiang Province and Anhui Province, China. Kernel of Carya cathayensis Sarg, which is well-known for the daintiness and nutritional content, is popular and very delicious food in eastern China. In this paper, we investigated the physiochemical properties and nutrient gradients of the kernel oil of Carya cathayensis Sarg. The results showed that the kernel oil of Carya cathayensis Sarg contained 63% of fat, 9.1% of proteins, 3.6% of starch and 4.6% of soluble proteins (based ration of weight). The compositions of the fatty acids were very similar to olive oil, and the total unsaturated fatty acids were 94%. Meanwhile, the kernel oil of Carya cathayensis Sarg also contained some polyphenols such as vanillic acid, ferulic acid, 3-methoxybenzoic acid and quercetin. The content of total polyphenols was 9.7 μg/g. Furthermore, the kernel oil of Carya cathayensis Sarg also contained some trace amount of squalene, β-Sitosterol, Vitamin E.
Chemistry of the Main Component of Essential Oil of Litsea cubeba and Its Derivatives  [PDF]
Lisong Hu, Menghao Du, Jingping Zhang, Yangdong Wang
Open Journal of Forestry (OJF) , 2014, DOI: 10.4236/ojf.2014.45050
Abstract: The tree of Litsea cubeba is widely spread in China, Indonesia and other part of Southeast Asia. The essential oil of Litsea cubeba (EOLC) is obtained by steam distillation from the pepper-like fruits tree Litsea cubeba. The EOLC consists of about 29 active compounds. Among them, citral is the main component; the content of citral is nearly 80% of the EOLC. Due to the special function group, citral is easy to react with many chemicals. Thus, EOLC is usually applied as starting material to carry out aldol condensation, reduction, and six-member ring forming reaction. The EOLC is extensively employed to synthesis of geranal nitriles, pseudonoe, ionone, methyl ionone, Vitamin E and Vitamin A. These products are broadly applied in the fields of fragrance, perfume, medicine and so on. This paper presents comprehensive utilization of EOLC as raw materials to synthesize many active chemicals.
Present Situation and Prospective of Camellia Nut Shells Utilization  [PDF]
Jinping Zhang, Lisong Hu, Zhoulian Wang, Menghao Du, Xiaohua Yao
Open Journal of Forestry (OJF) , 2015, DOI: 10.4236/ojf.2015.57066
Abstract: With the rapid development of Camellia oleifera industry, more and more Camellia nut shells have been produced, leading to serious environmental pollution problem. This paper reviews the works on the characterization of the physical and chemical properties of Camellia nut shells, active ingredient extraction, its application in chemical production, growing media and animal feed and its properties as a biomass. Based on the review, we proposed a novel all-component high value application strategy to covert camellia nut shells into high value biomasses, which could realize waste recycling and environmental protection.
Anti-Fatigue Effect of Blended Camellia oleifera Abel Tea Oil and Ge-132 in Mice  [PDF]
Lisong Hu, Xuezhi Fang, Menghao Du, Jingping Zhang
Food and Nutrition Sciences (FNS) , 2015, DOI: 10.4236/fns.2015.615152
Abstract: Nowadays, people are busier and busier for working and living, and suffer a lot of pressure on their body or mind. Therefore, people are prone to have fatigue activity and decrease their working efficiency and happiness. It was reported that fatigue is a common symptom in the community, with up to half of the general population complaining of fatigue. More and more researchers devoted themselves to studying natural active ingredients in organism as the anti-fatigue drugs to release fatigue symptom. However, these natural ingredients were difficult to obtain from plants, animals and microorganisms by separating and purifying. In addition, some active substances have many side effects. In our study, we employed tea seed oil as main ingredients blended with bis-(carboxyethylgermanium) sesquioxide (Ge-132) to investigate the effects of anti-fatigue on mice by administrating mice with low dose, intermediate dose and high dose of tea seed oil complex for 0, 2 or 4 weeks. The specific tests of studying effects of anti-fatigue were body weight, weight-loaded force swimming, blood urea nitrogen, blood lactic acid and hepaticglycogen. And the results showed that appropriate level of tea seed oil complex could decrease the body weight and prolong the weight-loaded swimming time, and had an active effect on the bloodurea nitrogen, hepatic glycogen and blood lactic acid level mice, which significantly embodied the anti-fatigue activity of tea seed oil complex.
Isolation of Total Saponins from Sapindus mukorossi Gaerth  [PDF]
Menghao Du, Sumei Huang, Jinping Zhang, Jingwen Wang, Lisong Hu, Jingmin Jiang
Open Journal of Forestry (OJF) , 2014, DOI: 10.4236/ojf.2014.41004

The study has been carried out to investigate the effects of single factors such as solvents extraction temperature, times, solid-liquid ration, and the time of extractions on the yields of saponins present in the pulp of Sapindus mukorossi Gaerth. On this basis, an L9 orthogonal design of experiment was adopted to determine the optimal conditions for the extraction of saponins. The factors that influence the extraction of saponins are put in the order of extraction times, extraction time, solid-liquid ration, and the best combination is that the powder of the pulp is extracted with EtOH (solid-to-solvent ratio = 1:8, w/v) for three times at 60°C for 3 hours. Under these conditions, about 1.63 g saponins will be extracted from 10 g raw material. The stability test showed that the Sapindus mukuross saponins can maintain surface activity at water temperature (25°C - 40°C), pH (6.3 - 7.7) and water hardness (50 - 250 mg.L-1). It is proved that Sapindus mukuross saponins are quality non-ionic active agent.

Toxicolological Test of Saponins from Sapindus mukorossi Gaerth  [PDF]
Menghao Du, Sumei Huang, Jinping Zhang, Jingwen Wang, Lisong Hu, Jingmin Jiang
Open Journal of Forestry (OJF) , 2015, DOI: 10.4236/ojf.2015.57067
Abstract: The study has been carried out to investigate acute oral toxicity, acute dermal toxicity in SPF rats and dermal irritation in rabbits. The result shows: 1) acute oral toxicity test shows that LD50 of saponins from Sapindus mukorossi is 9260 mg/kg (95% confidence interval is 6360 - 13,500 mg/kg) and 7940 mg/kg (95% confidence interval is 4890 - 12,900 mg/kg); 2) acute dermal toxicity test shows that LD50 of saponins from Sapindus mukorossi is more than 5000 mg/kg in both female and male Wistar rats; 3) dermal irritation test in rabbits shows that the average score of dermal irritation per day of each rabbit is zero after 14 days of continuous dermal irritation. According to the classification standard of toxicity in “Hygienic Standard for Cosmetics” (2002 version), the sample is classified as “practical nontoxic” and “non dermal irritation”. Thus, we can conclude that the saponin extraction from S. mukorossi Gaerth is safe for cosmetics.
Coating of Mineral Acids with Niobic Solid Acid for Preparing Furfural from Nut Shell of Camellia oleifera Abel  [PDF]
Lisong Hu, Menghao Du, Jingping Zhang
Open Journal of Forestry (OJF) , 2016, DOI: 10.4236/ojf.2016.65037
Abstract: Nut shell of Camellia oleifera Abel which has large scale of plantation in mountainous region of southern China is abundant renewable resource. The nut shell is suitable for preparation of furfural, as the content of which is as much as 16% (based the dried nut shell). In early time, mineral acids were employed as typically catalyst for preparing of furfural from the nut shells. These mineral acids could pollute water and corrode equipment. In this paper we used various mineral acids coating with niobic acid as catalysts to investigate reactions for preparation of furfural. Among these catalysts, the catalyst of sulfuric acid coating with niobic acid was found to be very effective, which had higher hammett acidity and better effect of hydrolysis of the nut shells; The catalysts of sulfuric acid coating with niobic acid was characterized, and the conditions of preparation of the catalyst were investigated. The optimum conditions were: sulfuric acid as coating acid, the concentration of sulfuric 1.1 mol/L, impregnation time 8 h, calcination time 8 h and calcination temperature 450°C. Then hydrolysis of the nut shells was explored, the optimum conditions were as follows: dose of catalyst 20%, ratio of solid to liquid 1:15, reaction temperature 100°C, reaction time 4 h; Under this condition, the yield of furfural was 8.7%.
Hemicellulose-Based Hydrogels Present Status and Application Prospects: A Brief Review  [PDF]
Lisong Hu, Menghao Du, Jinping Zhang
Open Journal of Forestry (OJF) , 2018, DOI: 10.4236/ojf.2018.81002
Abstract: Hemicellulose is one of the most abundant natural resources, which extensively exist in the pant tissues as the compositions of the cell wall filling between lignin and cellulose. In this review, the hemicellulose based hydrogels was illustrated in details including the hemicellulose derivatives (such as precursor of hemicellulose based hydrogel), hydrogels fabrication methods, origin of hemicellulose, composite hydrogels, and so on. In addition, the authors as well overviewed the new methods for fabrication of hemicellulose based hydrogels and special functional hemicellulose based hydrogels.
Quantitative Analysis Method of the Tea Saponin  [PDF]
Menghao Du, Shaohai Guo, Jinping Zhang, Lisong Hu, Mingze Li
Open Journal of Forestry (OJF) , 2018, DOI: 10.4236/ojf.2018.81005
Abstract: In this study, the detection method of tea saponin has been studied firstly. Determining the maximum absorption wavelength is 540 nm. Standard curve equation is y = 0.0015x - 0.0885. The correlation coefficient r = 0.9983 (p < 0.01). The relative standard deviation is 1.13%. Reclaimable rate of adding standard sample is 89.5% - 97.7%. Comparing vanille-sulfuric acid of gravimetric determination, the maximum deviation is 3.27%, indicating that vanille-sulfuric acid method is worth of quantitative analysis of tea saponin.
Lin28 Mediates Paclitaxel Resistance by Modulating p21, Rb and Let-7a miRNA in Breast Cancer Cells
Kezhen Lv, Liqun Liu, Linbo Wang, Jiren Yu, Xiaojiao Liu, Yongxia Cheng, Minjun Dong, Rongyue Teng, Linjiao Wu, Peifen Fu, Wuguo Deng, Wenxian Hu, Lisong Teng
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0040008
Abstract: Resistance to chemotherapy is a major obstacle for the effective treatment of cancers. Lin28 has been shown to contribute to tumor relapse after chemotherapy; however, the relationship between Lin28 and chemoresistance remained unknown. In this study, we investigated the association of Lin28 with paclitaxel resistance and identified the underlying mechanisms of action of Lin28 in human breast cancer cell lines and tumor tissues. We found that the expression level of Lin28 was closely associated with the resistance to paclitaxel treatment. The T47D cancer cell line, which highly expresses Lin28, is more resistant to paclitaxel than the MCF7, Bcap-37 or SK-BR-3 cancer cell lines, which had low-level expression of Lin28. Knocking down of Lin28 in Lin28 high expression T47D cells increased the sensitivity to paclitaxel treatment, while stable expression of Lin28 in breast cancer cells effectively attenuated the sensitivity to paclitaxel treatment, resulting in a significant increase of IC50 values of paclitaxel. Transfection with Lin28 also significantly inhibited paclitaxel-induced apoptosis. We also found that Lin28 expression was dramatically increased in tumor tissues after neoadjuvant chemotherapy or in local relapse or metastatic breast cancer tissues. Moreover, further studies showed that p21, Rb and Let-7 miRNA were the molecular targets of Lin28. Overexpression of Lin28 in breast cancer cells considerably induced p21 and Rb expression and inhibited Let-7 miRNA levels. Our results indicate that Lin28 expression might be one mechanism underlying paclitaxel resistance in breast cancer, and Lin28 could be a potential target for overcoming paclitaxel resistance in breast cancer.
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