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Search Results: 1 - 10 of 59099 matches for " Lingli Yang "
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Dysregulation of Circular Antigen-Specific T Cells Anergy in Autoimmune Vitiligo  [PDF]
Atsushi Tanemura, Lingli Yang, Ichiro Katayama
Journal of Cosmetics, Dermatological Sciences and Applications (JCDSA) , 2018, DOI: 10.4236/jcdsa.2018.83015
Abstract: Background: Vitiligo is an autoimmune disorder related to melanocyte loss; however, the exact interplay between antigen-specific autoimmunity and local oxidative stress remains unclear. Recently, the migration ability and number of Foxp3-expressing regulatory T cells (Tregs) in lesional skin was found to be reduced in vitiligo patients. Objectives: We aimed to clarify the T cell anergy status of melanocytes by focusing on the impaired equivalence of peripheral melanocyte-specific cytotoxic T cells and functional Tregs in patients with progressive vitiligo. Materials and methods: Ten progressive vitiligo patients and 10 age-matched healthy individuals were enrolled in this study. We analyzed the number of functional Tregs in progressive vitiligo patients and compared the findings with those of controls. Next, to assess the suppressive activity of Tregs on melanocyte-specific T lymphocytes, we strictly purified the functional Tregs fraction and Melan-A-specific CD8+ T cells and co-cultured these cells with each other. The number of Melan-A-specific CD8+ T cells was then counted by FACS. In addition, the expression of the representative exhaustion markers PD-1 and CTLA-4 on functional Tregs was assessed in vitiligo patients and normal controls. Results: The number of functional Tregs itself was not significantly decreased in the blood of vitiligo patients compared to healthy controls. However, the cytotoxic T cell (CTL) proliferation was significantly decreased after cultivation with Tregs from healthy individuals (p < 0.01), and this decrease in CTLs was less marked after cultivation with Tregs from vitiligo patients. Conclusions: We demonstrated a reduced suppressive function of activated Tregs on Melan-A-specific CTLs in the circulating cells of vitiligo patients compared with healthy controls. This result suggests that T cell anergy with Tregs dysfunction may participate in the immune response to melanocytes in vitiligo patients.
A note on the sign (unit root) ambiguities of Gauss sums in index 2 and 4 cases
Jing Yang,Lingli Xia
Mathematics , 2009, DOI: 10.1007/s11464-012-0217-2
Abstract: Recently, the explicit evaluation of Gauss sums in the index 2 and 4 cases have been given in several papers (see [2,3,7,8]). In the course of evaluation, the sigh (or unit root) ambiguities are unavoidably occurred. This paper presents another method, different from [7] and [8], to determine the sigh (unit root) ambiguities of Gauss sums in the index 2 case, as well as the ones with odd order in the non-cyclic index 4 case. And we note that the method in this paper are more succinct and effective than [8] and [7].
Complete Solving for Explicit Evaluation of Gauss Sums in the Index 2 Case
Jing Yang,Lingli Xia
Mathematics , 2009, DOI: 10.1007/s11425-010-3155-z
Abstract: Let $p$ be a prime number, $q=p^f$ for some positive integer $f$, $N$ be a positive integer such that $\gcd(N,p)=1$, and let $\k$ be a primitive multiplicative character of order $N$ over finite field $\fq$. This paper studies the problem of explicit evaluation of Gauss sums in "\textsl{index 2 case}" (i.e. $f=\f{\p(N)}{2}=[\zn:\pp]$, where $\p(\cd)$ is Euler function). Firstly, the classification of the Gauss sums in index 2 case is presented. Then, the explicit evaluation of Gauss sums $G(\k^\la) (1\laN-1)$ in index 2 case with order $N$ being general even integer (i.e. $N=2^{r}\cd N_0$ where $r,N_0$ are positive integers and $N_03$ is odd.) is obtained. Thus, the problem of explicit evaluation of Gauss sums in index 2 case is completely solved.
Inquiry of Water-Soluble Polysaccharide Extraction Conditions from Grapefruit Skin  [PDF]
Shiyu Tan, Qiliang Xu, Ziping Luo, Zilin Liu, Haiyan Yang, Lingli Yang
Engineering (ENG) , 2011, DOI: 10.4236/eng.2011.311135
Abstract: Water-soluble polysaccharide was isolated from grapefruit with the method of water-dissolving and ethanol-precipitating. By single factor test and orthogonal experimental method, the extraction conditions of the water-soluble polysaccharide were investigated, which contained liquid-solid ratio, temperature, time and pH. The results showed that pH was the most important factor of polysaccharide extraction, followed by temperature. The optimized extraction technology conditions were obtained. The liquid-solid ratio was 1:40, temperature was 90?C, time was 2.0 h, and pH was 2. The highest extraction rate of crude polysaccharide was 8.30%.
Improved Non-Local Means Algorithm for Image Denoising  [PDF]
Lingli Huang
Journal of Computer and Communications (JCC) , 2015, DOI: 10.4236/jcc.2015.34003
Abstract: Image denoising technology is one of the forelands in the field of computer graphic and computer vision. Non-local means method is one of the great performing methods which arouse tremendous research. In this paper, an improved weighted non-local means algorithm for image denoising is proposed. The non-local means denoising method replaces each pixel by the weighted average of pixels with the surrounding neighborhoods. The proposed method evaluates on testing images with various levels noise. Experimental results show that the algorithm improves the denoising performance.
Weight Distributions of a Class of Cyclic Codes with Arbitrary Number of Zeros II
Jing Yang,Lingli Xia,Maosheng Xiong
Mathematics , 2014,
Abstract: Cyclic codes are an important class of linear codes, whose weight distribution have been extensively studied. So far, most of previous results obtained were for cyclic codes with no more than three zeros. Recently, \cite{Y-X-D12} constructed a class of cyclic codes with arbitrary number of zeros, and computed the weight distributions for several cases. In this paper, we determine the weight distribution for a new family of such codes. This is achieved by certain new methods, such as the theory of Jacobi sums over finite fields and subtle treatment of some complicated combinatorial identities.
Development and Validation of an HPLC Method for Simultaneous Determination of Nine Active Components in ‘Da-Chai-Hu-Tang’  [PDF]
Lingli Zheng, Deshi Dong
Chinese Medicine (CM) , 2011, DOI: 10.4236/cm.2011.21004
Abstract: In this study, a simple, reliable and accurate method for the simultaneous separation and determination of naringin, hesperidin, neohesperidin, baicalin, wogonoside, baicalein, wogonin, emodin and chrysophanol in ‘Da-Chai-Hu-Tang’ was developed by reverse-phase high-performance liquid chromatography (RP-HPLC). The chromatographic separation was performed on an Agilent ZORBAX C18 column (250 mm × 4.6 mm i.d., 5.0 μm), and the mobile phase composed of methanol and water containing 1% (v/v) acetic acid was used to elute the targets in a gradient elution mode. The flow rate and detection wavelength were set at 0.8 ml/min and 280 nm, respectively. All calibration curves of the nine components expressed good linearities (r2≥0.9992) within the tested ranges. The RSD values demonstrated the intra- and inter-day precisions were less than 2.89%, and the recoveries of the investigated compounds were between 96.22% and 105.28%. The proposed method is simple, precise, specific, sensitive, and successfully applied to determine the nine marker compounds in ‘Da-Chai-Hu-Tang’ for quality control.
The Effects of Meteorological Factors Anomalies on Oceanic Coral Reef Systems in the Northwestern South China Sea  [PDF]
Lingli Fan, Yuchun Shen
Journal of Geoscience and Environment Protection (GEP) , 2015, DOI: 10.4236/gep.2015.32004

Climate warming, variation of East Asian atmospheric system have affected the Chinese offshore environment through the air-sea interaction, the coastal waters of South China Sea had been influenced, leading a corresponding impact on the coral reef growth. This paper reports on coral coverage and dominant coral species changes in Xu wen National Coral Reef Nature Reserve, examines their relationship with meteorological factors anomalies recorded by satellite. The study reveals that: compared to the period from 1979 to 2003, the temperature of surface coastal water dropped significantly in South China Sea in 2004-2008, the divergence of low layer of atmosphere over it strengthened, produced a zonal westerly anomaly field, which had an opposite direction to the local northeastern trade wind. The increasing of suspended matter in water, the decreasing of down welling in northwestern South China Sea, made the water quality deteriorating, water transparency decreased significantly, coral reef survival environment worsened, which would cause adverse effects on coral reef building capacity in the Reserve. Continued monitoring efforts are necessary to further assess the relationship between coral building capacity and in situ meteorological factors anomalies and improve the use of the dataset in future regional degradation predictions.

Analyzing the Causes of the Dissolution of the Former Yugoslav Federation from the Perspective of Ethnicity Relations
Lingli Zhang
International Education Studies , 2008, DOI: 10.5539/ies.v1n2p111
Abstract: The split and continual civil war of Yugoslav, which once caused deep concern by the international community, has its complex specific reasons. But for a long time, the tense relations among the ethnic groups are the underlying factors that caused the disintegration of Yugoslav. The harmonious ethnicity relations will promote national prosperity. Otherwise, it will accelerate its demise. Some Chinese experts and scholars have begun to ponder over the development and the future of Chinese socialism. They are aware of the significance to constitute a reasonable ethnic policy to deal with ethnicity relations. This paper tries to give a systematic analysis of the breakup of the former Yugoslav Federation from the perspective of ethnicity relations. And it also tries to get something of inspiration.
Analysis of Metal Element Distributions in Rice (Oryza sativa L.) Seeds and Relocation during Germination Based on X-Ray Fluorescence Imaging of Zn, Fe, K, Ca, and Mn
Lingli Lu, Shengke Tian, Haibing Liao, Jie Zhang, Xiaoe Yang, John M. Labavitch, Wenrong Chen
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0057360
Abstract: Knowledge of mineral localization within rice grains is important for understanding the role of different elements in seed development, as well as for facilitating biofortification of seed micronutrients in order to enhance seeds’ values in human diets. In this study, the concentrations of minerals in whole rice grains, hulls, brown rice, bran and polished rice were quantified by inductively coupled plasma mass spectroscopy. The in vivo mineral distribution patterns in rice grains and shifts in those distribution patterns during progressive stages of germination were analyzed by synchrotron X-ray microfluorescence. The results showed that half of the total Zn, two thirds of the total Fe, and most of the total K, Ca and Mn were removed by the milling process if the hull and bran were thoroughly polished. Concentrations of all elements were high in the embryo regions even though the local distributions within the embryo varied between elements. Mobilization of the minerals from specific seed locations during germination was also element-specific. High mobilization of K and Ca from grains to growing roots and leaf primordia was observed; the flux of Zn to these expanding tissues was somewhat less than that of K and Ca; the mobilization of Mn or Fe was relatively low, at least during the first few days of germination.
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