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Search Results: 1 - 10 of 3267 matches for " Linda Wauben "
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Insights from Stakeholders of Five Residential Smart Grid Pilot Projects in the Netherlands  [PDF]
Uchechi Obinna, Peter Joore, Linda Wauben, Angele Reinders
Smart Grid and Renewable Energy (SGRE) , 2016, DOI: 10.4236/sgre.2016.71001
Abstract: This paper presents insights and perceptions of stakeholders involved in the development and implementation of residential smart grid pilot projects in the Netherlands, adding to the limited information that is currently available in this area, while expectations about the potential benefits of smart grids are high. The main research questions of this study are: (1) How have some typical residential smart grid pilots in the Netherlands been set up? (2) Which stakeholders are involved in these pilots in the year 2014? (3) What are their views and perceptions with regards to the development and performance of residential smart grids? and (4) What do these stakeholders think about the products and services that may support an active participation of end-users in a smart energy home? To obtain information, we evaluated five residential smart grid pilot projects where smart energy products and services have been implemented. Semi-structured interviews were conducted with nine stakeholders involved in these projects. The Strategic Niche management framework was used to identify the present state of development and implementation of smart grid pilots. Our study shows that in the Netherlands residential smart grid pilots have been set-up and funded mainly by the government and grid operators. Other stakeholders involved include energy suppliers, end-users (as an energy cooperative or individual household), product and service suppliers, Information and Communication Technology (ICT) companies, and knowledge institutes. Currently a technology-push approach exists which barely includes an integrated approach towards smart grids products and services development. To the opinion of the interviewed stakeholders, current products and services offered in residential smart grid pilots are functionally attractive, but often too technically complex for the understanding of end-users. Hence, the general view held by respondents is that end-users should be the starting point in the development of smart grid products and services at the residential areas.
CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis
Elmieke PJ Boot, Gerben A Koning, Gert Storm, Josée PA Wagenaar-Hilbers, Willem van Eden, Linda A Everse, Marca HM Wauben
Arthritis Research & Therapy , 2005, DOI: 10.1186/ar1722
Abstract: In several autoimmune diseases, for example rheumatoid arthritis, the involvement of CD4+ T cells in disease induction has been suggested [1]. As a treatment strategy, the manipulation of CD4+ T cells by CD4-directed antibodies has therefore been studied extensively [2]. However, because anti-CD4 therapy targets the whole CD4+ population, CD4+ T cells not related to the disease or involved in disease regulation will also be affected. Ideally, only the auto-aggressive CD4+ T cells that are involved in the disease process should be targeted. Because for many human autoimmune diseases the exact antigens recognized by these cells are not known, a therapy would be favorable that specifically targets the auto-aggressive CD4+ T cells and does not depend on the definition of the crucial auto-antigen.Because auto-reactive CD4+ T cells become activated upon recognition of their cognate antigen in the periphery, they will be transiently marked by the expression of T cell activation markers. In this respect, CD134 (OX40 antigen) is an interesting candidate target molecule, because CD134 is expressed in vivo exclusively on activated CD4+ T cells (reviewed in [3]). In experimental autoimmune encephalomyelitis, a disease model for multiple sclerosis, it has been shown that CD134 is preferentially expressed on pathogenic CD4+ T cells that home to the target organ (namely the central nervous system) [4], and transiently marks the auto-aggressive T cells specific for myelin basic protein [5]. Moreover, in this T cell transfer model, depletion of CD134+ T cells with an anti-CD134 immunotoxin results in the amelioration of paralytic symptoms [6]. Interestingly, in patients with rheumatoid arthritis a high percentage of CD4+ T cells in synovial fluid express CD134 in comparison with peripheral blood T cells [6,7], suggesting that auto-aggressive CD4+ T cells may be transiently marked by surface expression of CD134 in arthritis too.Here, we investigated whether CD134 can be used as a tar
Creative Expression: Effectiveness of a Weekly Craft Group with Women Who Have Experienced Trauma  [PDF]
Linda Garner
Open Journal of Nursing (OJN) , 2015, DOI: 10.4236/ojn.2015.52011
Abstract: Creativity interventions have been shown to positively influence psychological and emotional health indicators. Nurses can play an important role in the development and implementation of interventions designed to counter the longer-term emotional and psychological consequences of trauma. The purpose of this study was to explore how participation in a nurse-facilitated weekly craft group may influence anxiety, depression, self-esteem, and self-confidence among women who have emotional and physical experienced trauma. A pre/post visual analog scale was used during a 7-week intervention to measure changes in anxiety, depression, stress, self-esteem and self-confidence among a convenience sample of adult female trauma survivors (n = 33). A paired sample t test was used to evaluate the intervention with significance set at p = 0.05. Participant observation and field notes were used for qualitative data generation. Significant reductions were noted in anxiety, depression, and stress along with significant increases in self-esteem and self-confidence. Cohen’s d statistic indicated a large effect size for anxiety (0.72) and stress (0.69). Moderate effect size was determined for self-confidence (0.36), depression (0.41), and self-esteem (0.52). Emergent qualitative themes included: creative expression improved confidence to sooth the self, safe spaces fostered creativity, a sense of accomplishment was stimulated through creative activities, and creative expression groups provided opportunities for positive affirmation. Offered as a complementary intervention, nurse-facilitated creative expression groups can support continued healing long after traditional support services have been exhausted. It is important for nurses to pursue a greater understanding of the art of nursing and the important contribution of creativity when used as a nursing intervention with trauma survivors.
Residual Effects from Occupational Mercury Exposure Include a Proposed Mercury Tremor Biomarker or “Fingerprint”  [PDF]
Linda Jones
Journal of Environmental Protection (JEP) , 2017, DOI: 10.4236/jep.2017.810068
Abstract: The study investigated residual effects of high levels of occupational mercury exposure, 30 years after a cohort of women worked in public service dentistry. They had all used copper amalgam in a pellet form that required heating and handling, and silver amalgam before the encapsulated form was available. Mercury handling practices changed in the mid-1970 when the workforce was urine tested and mercury poisoning became apparent. The aim was to compare control group and exposed group scores on tasks from a neurobehavioural test battery; plus survey results from a composite health, work history and environmental influences survey. The findings showed that the exposed and control groups were equivalent not only on those variables that one would want to be matched (age, alcohol consumption), but also on many of the cognitive and psychomotor test scores. The present paper focuses on psychomotor skill and tremor patterns. Tremor patterns were seen as generating new evidence of long term effects of the historic mercury insult. Data also suggest that there may be a distinctive mercury “fingerprint”, in samples of sinusoidal waveforms that may have potential as a non-invasive sub-clinical biomarker for adverse effects of mercury exposure, in screening or workplace monitoring.
Greenhouse effects of aircraft emissions as calculated by a radiative transfer model
J. P. F. Fortuin,R. van Dorland,W. M. F. Wauben,H. Kelder
Annales Geophysicae (ANGEO) , 2003,
Abstract: With a radiative transfer model, assessments are made of the radiative forcing in northern mid-latitudes due to aircraft emissions up to 1990. Considered are the direct climate effects from the major combustion products carbon dioxide, nitrogen dioxide, water vapor and sulphur dioxide, as well as the indirect effect of ozone production from NOx emissions. Our study indicates a local radiative forcing at the tropopause which should be negative in summer (–0.5 to 0.0 W/m2) and either negative or positive in winter (–0.3 to 0.2 W/m2). To these values the indirect effect of contrails has to be added, which for the North Atlantic Flight Corridor covers the range –0.2 to 0.3 W/m2 in summer and 0.0 to 0.3 W/m2 in winter. Apart from optically dense non-aged contrails during summer, negative forcings are due to solar screening by sulphate aerosols. The major positive contributions come from contrails, stratospheric water vapor in winter and ozone in summer. The direct effect of NO2 is negligible and the contribution of CO2 is relatively small.
Thromboelastography: Current Applications, Future Directions  [PDF]
Linda M. Trapani
Open Journal of Anesthesiology (OJAnes) , 2013, DOI: 10.4236/ojanes.2013.31007
Abstract:

Analyzing coagulability often hinges on patient surveillance using prothrombin time (PT) or international normalized ratio (INR) and activated partial thromboplastin time (aPTT) to monitor the extrinsic and intrinsic coagulation pathways, respectively A more complete assessment, however, can often be obtained using thromboelastography (TEG), a coagulation assay that evaluates the efficiency of clot formation, as well as the viscoelastic properties of the clot. Developed by Dr. Helmut Hartert in 1948 at the UniversityofHeidelberg, it provides information regarding hemostasis as a dynamic process [1,2]. Here, the TEG technique will be described, as well as its current applications and future directions for its use.

Feasibility of bioelectric impedance as a measure of muscle mass in mechanically ventilated ICU patients  [PDF]
Linda L. Chlan
Open Journal of Nursing (OJN) , 2014, DOI: 10.4236/ojn.2014.41008
Abstract:

Background: Critically ill patients receiving prolonged mechanical ventilatory support are at risk for loss of muscle mass and muscle strength from immobility. Feasible, non-invasive methods are needed to accurately obtain data on markers of muscle mass to design effective interventions and monitor patient progress during recovery from critical illness. Bioelectric impedance has been used in other settings to obtain data on body composition and muscle mass. Purpose: The aims of this study were to determine the feasibility of bioelectric impedance as a marker of muscle mass in a sample of mechanically ventilated patients and to assess data trends in these obtained values. Methods: A descriptive design was used to obtain standard bioelectric impedance parameters (total body resistance, legs resistance, and percent lean body mass) over 4 days from eligible patients already enrolled in a randomized clinical trial. Results: Bioimpedance parameters were readily obtained over 4 days in a sample of 43 patients (age 59 + 15.7 years, 56% male) receiving prolonged ventilatory support (mean 9.4 + 10.4 days) due to respiratory failure. Reasons for not obtaining impedance measures included skin impairment, monitoring devices, or presence of implantable cardiac defibrillator or pacemaker. Average total body impedance was 464.3 + 117.1 ohms, while average impedance of legs was 479.1 + 146.4 ohms. Lean body mass was 68.4% (+10.8). Conclusions/Implications for Practice: With carefully trained staff and a standardized measurement protocol, bioimpedance is a feasible method to obtain body composition data reflective of muscle mass in mechanically ventilated patients. Further research will determine the utility of bioimpedance to monitor recovery and effectiveness of interventions to restore function after prolonged periods of ventilatory support and immobility in mechanically ventilated patients.

Bioremediation of Lead(II) from Polluted Wastewaters Employing Sulphuric Acid Treated Maize Tassel Biomass  [PDF]
Mambo Moyo, Linda Chikazaza
American Journal of Analytical Chemistry (AJAC) , 2013, DOI: 10.4236/ajac.2013.412083
Abstract:

The ability to modify a waste by-product precursor, maize tassel biomass using sulfuric acid as the activating agent with specific focus on Lead(II) ion from water has been proposed. The treating of maize tassel using sulphuric acid is believed to enhance sorption capacity of Lead(II) ions. For this, batch adsorption mode was adopted for which the effects of initial pH, adsorbent dosage, contact time and initial concentration were investigated. Consequently, it was found that the adsorbent capacity depends on pH; since it increases up to 4.5 and then decreases. The highest percentage of Lead(II) ion removal was achieved in the adsorbent dosage of 1.2 g and at an initial concentration of 10 mg/L metal ion. In an attempt to determine the capacity and rate of Lead(II) removal, isotherm and kinetic data were modeled using appropriate equations. To this end, the adsorption data fitted best into the Langmuir model with an R2 (0.9997) while kinetically the Lead(II) adsorption followed the pseudo-second-order model. Furthermore, as a way to address issues related to sustainability, maize tassel is recommended since the process is considered to be a dual solution for environmental cleaning. From one side, it represents a better way to dispose the maize tassel which has no use after fertilization and on the other hand it is an economic source of carbonaceous materials.

 

A Higher Education Leadership Distance Ph.D. Program: An Assessment Using Blocher’s Ecological Learning Theory  [PDF]
Linda Kuk, James H. Banning
Creative Education (CE) , 2014, DOI: 10.4236/ce.2014.59082
Abstract:

This study utilized a case study approach to discuss the issues of distance education in the delivery of doctoral education. The case study provided abroad background to the issues of distance education graduate programs and an assessment of the case. Blocher’s (1974) Ecological Learning Theory is applied to the case to provide for analytical generalization. The results support the need for distance delivery of academic programs to consider both the content and the program’s delivery structure as important components in realizing student success.

Perceived Benefits of Incorporating Yoga into Classroom Teaching: Assessment of the Effects of “Yoga Tools for Teachers”  [PDF]
David Dapeng Chen, Linda Pauwels
Advances in Physical Education (APE) , 2014, DOI: 10.4236/ape.2014.43018
Abstract:

With rising health issues among children and adolescents in America such as obesity and diabetes, getting physically active becomes ever more important. Yoga, as an ancient system of exercise, has a great potential to teach children to be mindful of factors that impact their health and improve their total well-being. The purpose of this study was to examine the perceived benefits of incorporating yoga-based activities into classroom teaching as a result of implementing the Yoga Ed. Tools for Teachers program. One hundred and three physical education and classroom teachers were trained by certified Yoga Ed. instructors for two days. These teachers, in turn, implemented the yoga-based activities for 5 - 15 minutes daily for a year. At the completion of this period, questionnaires from 550 parents and 661 students as well as 103 teachers were analyzed. Triangulation of the data provided solid evidence suggesting that yoga-based activities produced perceived benefits in such areas as mental well-being, social well-being, physical well-being, and daily behaviors. The data analyses also revealed barriers teachers encountered during implementation and what they did to overcome these barriers. The results were discussed with regard to their future implications for yoga programs appropriate for schools in the United States (US).

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