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Search Results: 1 - 10 of 141399 matches for " Li Min;Cendes "
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Menstrual cycle worsening of epileptic seizures in women with symptomatic focal epilepsy
Bazán, Ana Carolina Belini;Montenegro, Maria Augusta;Cendes, Fernando;Min, Li Li;Guerreiro, Carlos A.M.;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000500006
Abstract: introduction: hormonal fluctuation is responsible for worsening of epileptic seizures during the menstrual cycle. objetive: to identify irregularities in the menstrual cycles of women with mesial temporal lobe epilepsy (mtle) and extratemporal focal epilepsy (etfe) and correlate the frequency of seizures during the menstrual cycles. method: we evaluated prospectively women in the menacme with mtle and etfe. calendars were provided for these patients, and they were asked to mark their seizure frequency according to the menses. calendars were reviewed in each routine medical appointment. results: thirty-nine patients with mtle and 14 with etfe were evaluated. we registered 211 cycles in the patients with mtle and 49 in those with etfe. irregular menstrual cycles were found in 28 (28/39, 71.7%) patients with mtle and 6 (6/14, 42.8%) with etfe (p=0.052). premenstrual seizure worsening was observed in 46 (21.8%) patients with mtle and 9 (18.3%) with etfe (p=0.596). menstrual worsening was observed in 47 (22.2%) patients with mtle and 15 (30.6%) with etfe (p=0. 217). ovulatory worsening was observed in 36 (17%) patients with mtle and 13 (26.5%) with etfe (p=0,126). catamenial worsening was observed in 58 (27.4%) of the patients with mtle and in 17 (34.7%) of the patients with etfe (p=0.315). conclusion: there was no difference between the group of patients with mtle and etfe regarding the frequency of irregular cycles and seizure worsening during the premenstrual, menstrual, catamenial or ovulatory periods.
Memory impairment in children with temporal lobe epilepsy: a review
Guimar?es, Catarina A.;Min, Li Li;Rzezak, Patrícia;Fuentes, Daniel;Franzon, Renata C.;Montenegro, Maria Augusta;Valente, Kette;Cendes, Fernando;Guerreiro, Marilisa M.;
Journal of Epilepsy and Clinical Neurophysiology , 2006, DOI: 10.1590/S1676-26492006000200005
Abstract: introduction: the authors present a review article on memory aspects of temporal lobe epilepsy in childhood. methods: we performed a search in the literature. results: temporal lobe epilepsy (tle) in childhood present with great clinical, electroencephalographic and etiological diversity. the neuropsychological features in children with tle are not well-defined yet. the relationship between the lateralization of the lesion and performance on memory tests is not established. conclusion: the studies performed in children with tle show controversy data. this finding may be due to the etiological, clinical and electroencephalographic diversity seen in such group of children. besides, most studies use different assessments. therefore, it is clear that more studies are necessary to elucidate which neuropsychological deficits occur in children with tle.
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil
Noronha, Ana Lúcia Andrade;Marques, Lúcia Helena;Borges, Moacir Alves;Cendes, Fernando;Guerreiro, Carlos Alberto Mantovani;Li, Li Min;
Arquivos de Neuro-Psiquiatria , 2004, DOI: 10.1590/S0004-282X2004000500003
Abstract: objective: to assess the epilepsy treatment gap in campinas and s?o josé do rio preto, two cities in the state of s?o paulo, brazil. method: the treatment gap was estimated using the formula n1-n2/n1x100, where n1 was calculated using 1.86% prevalence and represented the number of individuals with epilepsy, while n2 represented the number of people who could be treated with an adult standard dose for a year utilizing the antiepileptic drugs supplied by the public health system. results: our estimates revealed that in 2001, approximately 50% of the population with epilepsy was treated with the recommended antiepileptic medication. conclusion: these results suggest that a relevant percentage of patients with epilepsy are not untreated. further epidemiological studies are needed to investigate the reasons for this treatment gap so that interventions can reduce this gap and improve the quality of life of patients with epilepsy.
Statistical voxel-wise analysis of ictal SPECT reveals pattern of abnormal perfusion in patients with temporal lobe epilepsy
Amorim, Bárbara Juarez;Etchebehere, Elba Cristina Sá de Camargo;Camargo, Edwaldo Eduardo;Rio, Pablo Augusto;Bonilha, Leonardo;Rorden, Chris;Li, Li Min;Cendes, Fernando;
Arquivos de Neuro-Psiquiatria , 2005, DOI: 10.1590/S0004-282X2005000600014
Abstract: objective: to investigate the pattern of perfusion abnormalities in ictal and interictal brain perfusion spect images (bsi) from patients with temporal lobe epilepsy (tle). method: it was acquired interictal and ictal bsi from 24 patients with refractory tle. bsis were analyzed by visual inspection and statistical parametric mapping (spm2). statistical analysis compared the patients group to a control group of 50 volunteers. the images from patients with left-tle were left-right flipped. results: it was not observed significant perfusional differences in interictal scans with spm. ictal bsi in spm analysis revealed hyperperfusion within ipsilateral temporal lobe (epileptogenic focus) and also contralateral parieto-occipital region, ipsilateral posterior cingulate gyrus, occipital lobes and ipsilateral basal ganglia. ictal bsi also showed areas of hypoperfusion. conclusion: in a group analysis of ictal bsi of patients with tle, voxel-wise analysis detects a network of distant regions of perfusional alteration which may play active role in seizure genesis and propagation.
Tratamento de epilepsia: consenso dos especialistas brasileiros
Betting, Luiz Eduardo;Kobayashi, Eliane;Montenegro, Maria Augusta;Min, Li Li;Cendes, Fernando;Guerreiro, Marilisa M.;Guerreiro, Carlos A.M.;
Arquivos de Neuro-Psiquiatria , 2003, DOI: 10.1590/S0004-282X2003000600032
Abstract: epilepsy is a frequent condition in the world. recently a study in brazil showed prevalence of 18/1000 inhabitants in s?o josé do rio preto, s?o paulo state. in the last decade, new therapeutic options were discovered or developed. the main therapeutic decision method is based on randomized clinical trials. this method represents the higher level of evidence. however, even these studies have limitations and in some cases the treatment of choice remains controversial. in these instances, the epilepsy experts' opinions become helpful. in 2001 a similar study had been conducted in usa. the aim of this study is to create guidelines for epilepsy treatment based on the opinion of the brazilian experts. these guidelines can be used to create manuals and strategies for the treatment of some epileptic syndromes according to brazilian experts. as compared to the north-american guidelines our study better reflects the resources available in our country.
Brain SPECT in mesial temporal lobe epilepsy: comparison between visual analysis and SPM
Amorim, Bárbara Juarez;Ramos, Celso Darío;Santos, Allan Oliveira dos;Lima, Mariana da Cunha Lopes de;Min, Li Li;Camargo, Edwaldo Eduardo;Cendes, Fernando;Etchebehere, Elba Cristina Sá de Camargo;
Arquivos de Neuro-Psiquiatria , 2010, DOI: 10.1590/S0004-282X2010000200001
Abstract: objective: to compare the accuracy of spm and visual analysis of brain spect in patients with mesial temporal lobe epilepsy (mtle). method: interictal and ictal spects of 22 patients with mtle were performed. visual analysis were performed in interictal (visual(inter)) and ictal (visual(ictal/inter)) studies. spm analysis consisted of comparing interictal (spm(inter)) and ictal spects (spm(ictal)) of each patient to control group and by comparing perfusion of temporal lobes in ictal and interictal studies among themselves (spm(ictal/inter)). results: for detection of the epileptogenic focus, the sensitivities were as follows: visual(inter)=68%; visual(ictal/inter)=100%; spm(inter)=45%; spm(ictal)=64% and spm(ictal/inter)=77%. spm was able to detect more areas of hyperperfusion and hypoperfusion. conclusion: spm did not improve the sensitivity to detect epileptogenic focus. however, spm detected different regions of hypoperfusion and hyperperfusion and is therefore a helpful tool for better understand pathophysiology of seizures in mtle.
The Composition and Case Study of the Nurses’ Voluntary Turnover Cost in China  [PDF]
Min Li
Modern Economy (ME) , 2017, DOI: 10.4236/me.2017.86058
Abstract: Nurse is the largest number of four medical personnel, and the stability of the nurses is directly related to the quality of medical service, but countries around the world are faced with the high turnover rate of nurses [1]. At present, Chinese researches on the issue of nurses resignation mainly focus on the analysis of the variables and causes of nurses resignation, while there is few research related to the turnover costs of nurses which the managers focus most. All these problems lead to there is still no consensus and cognition on composition and measurement methods of turnover costs and the harm of the organizations. Based on the literature research, this paper summarizes the composition and measurement of the voluntary turnover cost of Chinese nurses, and draws the main constituent elements and feasible measurement methods of the nurses’ voluntary turnover cost. Furthermore, this paper takes a military hospital in Beijing as an example and shows the composition and measurement methods of turnover cost by the actual measurement of the nurses’ turnover costs in this hospital. Hope this paper can provide some reference for the future theoretical research and medical practice.
Research on the Innovative Practice of “The Flipped Classroom” in the Basic Management Course of Chinese Universities  [PDF]
Min Li
Creative Education (CE) , 2017, DOI: 10.4236/ce.2017.813146
Abstract: With the advancement of times and development of technology, the traditional teaching mode has gradually revealed some drawbacks. Therefore, a new teaching mode is needed. Flipped class, as one of the new teaching modes which can improve the students’ initiative and self-discipline, has attracted colleges and universities’ attention and exploration. Based on the teaching reform practice of the flipped classroom teaching mode of the basic management course in universities, this paper elaborates the significance and current situation of the flipped classroom practice in universities, and explores the specific schemes, procedures as well as the future development direction of the flipped classroom teaching mode of the basic management course. Through the analysis of these problems, we hope to contribute to the reform of flipped class teaching mode in universities, and provide some references for later research.
Clinical presentation of juvenile Huntington disease
Ruocco, Heloísa H.;Lopes-Cendes, Iscia;Laurito, Tiago L.;Li, Li M.;Cendes, Fernando;
Arquivos de Neuro-Psiquiatria , 2006, DOI: 10.1590/S0004-282X2006000100002
Abstract: objective: to describe the clinical presentation a group of patients with juvenile onset of huntington disease. method: all patients were interviewed following a structured clinical questioner. patients were genotyped for the trinucleotide cytosine-adenine-guanine (cag) repeat in the huntington disease gene. high resolution brain mri was performed in all patients. results: we identified 4 patients with juvenile onset of disease among 50 patients with huntington disease followed prospectively in our neurogenetics clinic. age at onset varied from 3 to 13 years, there were 2 boys, and 3 patients had a paternal inheritance of the disease. expanded huntington disease allele sizes varied from 41 to 69 trinucleotide repeats. the early onset patients presented with rigidity, bradykinesia, dystonia, dysarthria, seizures and ataxia. mri showed severe volume loss of caudate and putamen nuclei (p=0.001) and reduced cerebral and cerebellum volumes (p=0.01). conclusion: 8% of huntington disease patients seen in our clinic had juvenile onset of the disease. they did not present with typical chorea as seen in adult onset huntington disease. there was a predominance of rigidity and bradykinesia. two other important clinical features were seizures and ataxia, which related with the imaging findings of early cortical atrophy and cerebellum volume loss.
An Investigation and Analysis of Information Overload in Manager's Work  [PDF]
Tao Li, Min Li
iBusiness (IB) , 2011, DOI: 10.4236/ib.2011.31008
Abstract: The problem of information overload in management field has been receiving increasing attention, while there are less empirical researches now. This paper proposes a conceptual model and some operational variables, in which information overload is as an intervening variable between the factors of causes and impacts. An investigation and analysis has been conducted from a selected sample of managers. This research suggests that work efficiency and work quality are both not strongly connected with information overload. We also find that the main causes of information overload are the work interruption and work time pressure but the amount of information.
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