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Search Results: 1 - 10 of 410967 matches for " Laura M. Lessard "
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Cultural Sensitivity Associated with Domestic Travel Study Program: Long-Term Impact  [PDF]
Jessica R. Eosso, Marie Fanelli Kuczmarski, Ryan T. Pohlig, Laura M. Lessard, Sandra D. Baker
Creative Education (CE) , 2019, DOI: 10.4236/ce.2019.101008
Abstract: Domestic and international travel study programs have grown in length and popularity since they began in 1923. Regardless of the field of study, the goal of most programs is to enhance student cultural sensitivity. The purpose of this study was to explore the contribution of an undergraduate food-focused domestic travel study program on long-term cultural sensitivity based on the ASKED model. A travel study program focused on transcultural food and cuisine was initiated in 1987 and as of 2017, implemented 22 times. The program length varied between 3 and5 weeks and was offered in two locations in the United States. A survey developed to explore the long-term impact of the program incorporated the ASKED model of cultural competence. This model includes five domains: cultural awareness, skill, knowledge, encounters, and desire. The survey was validated and found to be reliable. University of Delaware alumni who participated in the travel study program (n = 461) and a comparison group of alumni (n = 402) who did not participate in the program were invited to complete the survey. The majority of respondents majored in nutrition and dietetics. Alumni who participated in the travel study program had significantly higher total cultural sensitivity scores and also higher scores on 3 domains, namely cultural skill, knowledge, and desire compared to those that did not. Of the 11 program activities participants were asked to rank as contributors to cultural sensitivity, dining experiences and farm to table tours were rated as the top two, respectively. The study findings provided evidence that a short-term, domestic travel study program enhanced long-term cultural sensitivity. Since domestic programs may be a more cost-effective option and align more closely with employment opportunities in healthcare than international travel programs for college graduates, educators should provide opportunities and encourage dietetic students to participate in these travel programs.
Rigorous numerics for ill-posed PDEs: periodic orbits in the Boussinesq equation
R. Castelli,M. Gameiro,J. -P. Lessard
Mathematics , 2015,
Abstract: In this paper, we develop computer-assisted techniques for the analysis of periodic orbits of ill-posed partial differential equations. As a case study, our proposed method is applied to the Boussinesq equation, which has been investigated extensively because of its role in the theory of shallow water waves. The idea is to use the symmetry of the solutions and a Newton-Kantorovich type argument (the radii polynomial approach), to obtain rigorous proofs of existence of the periodic orbits in a weighted $\ell^1$ Banach space of space-time Fourier coefficients with geometric decay. We present several computer-assisted proofs of existence of periodic orbits at different parameter values.
The Impact of Entropy on the Spatial Organization of Synaptonemal Complexes within the Cell Nucleus
Miriam Fritsche, Laura G. Reinholdt, Mark Lessard, Mary Ann Handel, J?rg Bewersdorf, Dieter W. Heermann
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0036282
Abstract: We employ 4Pi-microscopy to study SC organization in mouse spermatocyte nuclei allowing for the three-dimensional reconstruction of the SC's backbone arrangement. Additionally, we model the SCs in the cell nucleus by confined, self-avoiding polymers, whose chain ends are attached to the envelope of the confining cavity and diffuse along it. This work helps to elucidate the role of entropy in shaping pachytene SC organization. The framework provided by the complex interplay between SC polymer rigidity, tethering and confinement is able to qualitatively explain features of SC organization, such as mean squared end-to-end distances, mean squared center-of-mass distances, or SC density distributions. However, it fails in correctly assessing SC entanglement within the nucleus. In fact, our analysis of the 4Pi-microscopy images reveals a higher ordering of SCs within the nuclear volume than what is expected by our numerical model. This suggests that while effects of entropy impact SC organization, the dedicated action of proteins or actin cables is required to fine-tune the spatial ordering of SCs within the cell nucleus.
A universidade e a forma??o profissional dos docentes: novos questionamentos
Lessard, Claude;
Educa??o & Sociedade , 2006, DOI: 10.1590/S0101-73302006000100010
Abstract: with regard to the professional training of teachers in university settings, this paper presents an analysis of the present situation based on the rise of the state's insistence on greater effectiveness. it identifies three issues: 1) the necessary tensions between plural approaches to teacher development and school improvement; 2) the ways of dealing with forms of obligation of results in teacher training, and 3) the definition of "science" and "research" in the context of the return to prominence of "hard sciences". it argues that a university has more autonomy than a normal school and can hold itself aloof from certain perils. if university is unable of generating fruitful tensions between plural approaches to teacher development and school improvement; of sophisticatedly responding to the obligation of results; and of developing a critical relationship to science in teachers, who will be?
Regula??o múltipla e autonomia profissional dos professores: compara??o entre o Quebec e o Canadá
Lessard, Claude;
Educa??o em Revista , 2006, DOI: 10.1590/S0102-46982006000200008
Abstract: the paper deals with the relationships between models of regulation (bureaucratic, professionnal and market) of education and teacher autonomy. as espoused by professional and labour associations of canada and quebec, teacher autonomy is used to disclose the evolution of models of educational regulation. adopting a neo-institutionalist point of view, the paper argues that teacher autonomy, as promoted by canadian teacher unions, refers to activities considered central of teachers' work, as opposed to peripheral activities. this distinction helps understand why in canada a strong reaction against curriculum centralization and standardization of evaluation has been observed, whereas quebec teachers' unions seem to accommodate themselves with an increase in parental power. in both contexts (canada and quebec), a strong resistance to work reorganization is also noticeable.
State-space solution to a minimum-entropy $\mathcal{H}_\infty$-optimal control problem with a nested information constraint
Laurent Lessard
Mathematics , 2014,
Abstract: State-space formulas are derived for the minimum-entropy $\mathcal{H}_\infty$ controller when the plant and controller are constrained to be block-lower-triangular. Such a controller exists if and only if: the corresponding unstructured problem has a solution, a certain pair of coupled algebraic Riccati equations admits a mutually stabilizing fixed point, and a pair of spectral radius conditions is met. The controller's observer-based structure is also discussed, and a simple numerical approach for solving the coupled Riccati equations is presented.
A study of Pc-5 ULF oscillations
M. K. Hudson, R. E. Denton, M. R. Lessard, E. G. Miftakhova,R. R. Anderson
Annales Geophysicae (ANGEO) , 2004,
Abstract: A study of Pc-5 magnetic pulsations using data from the Combined Release and Radiation Effects Satellite (CRRES) was carried out. Three-component dynamic magnetic field spectrograms have been used to survey ULF pulsation activity for the approximate fourteen month lifetime of CRRES. Two-hour panels of dynamic spectra were examined to find events which fall into two basic categories: 1) toroidal modes (fundamental and harmonic resonances) and 2) poloidal modes, which include compressional oscillations. The occurence rates were determined as a function of L value and local time. The main result is a comparable probability of occurence of toroidal mode oscillations on the dawn and dusk sides of the magnetosphere inside geosynchronous orbit, while poloidal mode oscillations occur predominantly along the dusk side, consistent with high azimuthal mode number excitation by ring current ions. Pc-5 pulsations following Storm Sudden Commencements (SSCs) were examined separately. The spatial distribution of modes for the SSC events was consistent with the statistical study for the lifetime of CRRES. The toroidal fundamental (and harmonic) resonances are the dominant mode seen on the dawn-side of the magnetosphere following SSCs. Power is mixed in all three components. In the 21 dusk side SSC events there were only a few examples of purely compressional (two) or radial (one) power in the CRRES study, a few more examples of purely toroidal modes (six), with all three components predominant in about half (ten) of the events. Key words. Magnetospheric physics (MHD waves and instabilities; magnetospheric configuration and dynamics) – Space plasma physics (waves and instabilities) Full Article (PDF, 1098 KB) Citation: Hudson, M. K., Denton, R. E., Lessard, M. R., Miftakhova, E. G., and Anderson, R. R.: A study of Pc-5 ULF oscillations, Ann. Geophys., 22, 289-302, doi:10.5194/angeo-22-289-2004, 2004. Bibtex EndNote Reference Manager XML
Development and validation of the Treatment Related Impact Measure of Weight (TRIM-Weight)
Meryl Brod, Mette Hammer, Nana Kragh, Suzanne Lessard, Donald M Bushnell
Health and Quality of Life Outcomes , 2010, DOI: 10.1186/1477-7525-8-19
Abstract: The online validation battery survey was administered in four countries (the U.S., U.K., Australia, and Canada). Eligible subjects were over age eighteen, currently taking a prescription AOM and were currently or had been obese during their life. Validation analyses were conducted according to an a priori statistical analysis plan. Item level psychometric and conceptual criteria were used to refine and reduce the preliminary item pool and factor analysis to identify structural domains was performed. Reliability and validity testing was then performed and the minimally importance difference (MID) explored.Two hundred and eight subjects completed the survey. Twenty-one of the 43 items were dropped and a five-factor structure was achieved: Daily Life, Weight Management, Treatment Burden, Experience of Side Effects, and Psychological Health. A-priori criteria for internal consistency and test-retest coefficients for the total score and all five subscales were met. All pre-specified hypotheses for convergent and known group validity were also met with the exception of the domain of Daily Life (proven in an ad hoc analysis) as well as the 1/2 standard deviation threshold for the MID.The development and validation of the TRIM-Weight has been conducted according to well-defined principles for the creation of a PRO measure. Based on the evidence to date, the TRIM-Weight can be considered a brief, conceptually sound, valid and reliable PRO measure.The use of prescription anti-obesity medication (AOM) to treat obesity is becoming increasingly common as treatment options grow and become more accessible. However, AOM has been associated with a wide range of potentially negative impacts on patient functioning and well being. Unfortunately, the impact of AOM is far less well understood than the impact of obesity on Health Related Quality of Life (HRQoL). The main challenge in understanding these impacts is the absence of a conceptual and psychometrically sound treatment-specific m
Understanding and assessing the impact of treatment in diabetes: the Treatment-Related Impact Measures for Diabetes and Devices (TRIM-Diabetes and TRIM-Diabetes Device)
Meryl Brod, Mette Hammer, Torsten Christensen, Suzanne Lessard, Donald M Bushnell
Health and Quality of Life Outcomes , 2009, DOI: 10.1186/1477-7525-7-83
Abstract: Patient interviews were conducted to collect the patient perspective and ensure high content validity. Interviews were hand coded and qualitatively analyzed to identify common themes. A conceptual model of the impact of diabetes medication was developed and preliminary items for the TRIM-Diabetes/Device were generated and cognitively debriefed. Validation data was collected via an on-line survey and analyzed according to an a priori statistical analysis plan to validate the overall score as well as each domain. Item level criteria were used to reduce the preliminary item pool. Next, factor analysis to identify structural domains was performed. Reliability and validity testing was then performed.One hundred and five patients were interviewed in focus groups, individual interviews and for cognitive debriefing. Five hundred seven patients participated in the validation study. Factor analysis identified seven domains: Treatment Burden, Daily Life; Diabetes Management; Psychological Health; Compliance and Device Function and Bother. Internal consistency reliability coefficients of the TRIM-Diabetes/Device ranged from 0.80 and 0.94. Test-retest reliability of the TRIM-Diabetes/Device ranged from 0.71 to 0.89. All convergent and known groups validity hypotheses were met for the TRIM-Diabetes/Device total scores and sub-scales.Validation is an ongoing and iterative process. These findings are the first step in that process and have shown that both the TRIM-Diabetes and the TRIM-Diabetes Device have acceptable psychometric properties. Future research is needed to continue the validation process and examine responsiveness and the validity of the TRIM-Diabetes/Device in a clinical trial population.Diabetes is one of the most debilitating common illnesses and requires lifelong management, often including medication, to control blood glucose levels. Treatments can be varied in terms of mode of administration (oral, syringe, pen, pump) as well as type of anti-diabetic agent (e.g.
pB264, a small, mobilizable, temperature sensitive plasmid from Rhodococcus
Philip A Lessard, Xian M O'Brien, Devin H Currie, Anthony J Sinskey
BMC Microbiology , 2004, DOI: 10.1186/1471-2180-4-15
Abstract: We isolated and sequenced pB264, a 4,970 bp cryptic plasmid from Rhodococcus sp. B264-1 with features of a theta-type replication mechanism. pB264 was nearly identical to pKA22, a previously sequenced but uncharacterized cryptic plasmid. Derivatives of pB264 replicate in a diverse range of Rhodococcus species, showing that this plasmid does not bear the same host range restrictions that have been exhibited by other theta replicating plasmids. Replication or maintenance of pB264 is inhibited at 37°C, making pB264 useful as a suicide vector for genetic manipulation of Rhodococcus. A series of deletions revealed that ca. 1.3 kb from pB264 was sufficient to support replication and stable inheritance of the plasmid. This region includes two open reading frames that encode functions (RepAB) that can support replication of pB264 derivatives in trans. Rhodococcus sp. B264-1 will mobilize pB264 into other Rhodococcus species via conjugation, making it possible to genetically modify bacterial strains that are otherwise difficult to transform. The cis-acting element (oriT) required for conjugal transfer of pB264 resides within a ca. 0.7 kb region that is distinct from the regions responsible for replication.Shuttle vectors derived from pB264 will be useful for genetic studies and strain improvement in Rhodococcus, and will also be useful for studying the processes of theta replication and conjugal transfer among actinomycetes.Gram-positive bacteria of the genus Rhodococcus have shown an extraordinary capacity for metabolizing recalcitrant organic compounds. Due to these diverse enzymatic activities and a demonstrated solvent tolerance, rhodococci have many practical applications for bioconversion and bioremediation (reviewed in [1,2]). One hindrance to the full exploitation of Rhodococcus is the dearth of genetic tools available for strain manipulation. Among the most basic of tools for genetic manipulation of bacteria are plasmids. Plasmids can be used to introduce new or ext
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