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Search Results: 1 - 10 of 132807 matches for " LU Wei-yu "
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Changes in the anterior segment of eyes of children with different genetic background under different accommodations

DAI Yi-kang
, FU Wei-cai, LU Wei-yu, et al

- , 2016, DOI: 10.3969/j.issn.1674-8115.2016.01.016
Abstract: 目的 研究和分析不同遗传背景下,相同屈光状态儿童在不同的调节刺激下眼前节结构的变化。方法 采集正视眼儿童(+0.50~-0.50 DS)60例(60眼),分成2组:A组30例,儿童父母均为正视;B组30例,父母均为高度近视(≥6.0 DS)。所有受试儿童行散瞳主觉验光,调节放松和不同程度调节刺激下测量前房深度、晶状体厚度及暗瞳直径,比较两组间的差异。结果 两组儿童的年龄、调节幅度和裸眼视力差异均无统计学意义(P>0.05)。调节放松和诱发3D调节时两组间各测量指标的差异无统计学意义(P>0.05)。诱发6D调节时,A组前房深度变浅值和晶状体变厚值均大于B组(P<0.05),但暗瞳直径缩小值两组之间的差异无统计学意义(P>0.05)。结论 在6D调节刺激下,父母均为高度近视的儿童眼前节结构中前房深度以及晶状体厚度变化值均小于父母均为正视的儿童,这种差异是否造成今后屈光转归的不同尚需进一步研究。
: Objective To investigate and analyze the changes in the anterior segment of eyes of children with different genetic background and same refraction under different accommodations. Methods A total of 60 emmetropic children (60 eyes, +0.50~-0.50 DS) were enrolled and divided into A group (n=30) and B group (n=30). Parents of children of A group were emmetropic and parents of children of B group were highly myopic (≥6.0 DS). All children underwent subjective refraction after mydriasis. The anterior chamber depth, crystalline lens thickness, and dark pupil diameter were measured under relaxation and different accommodations. The difference between two groups was compared. Results The differences of age, accommodation amplitude, and naked vision between two groups were not statistically significant (P>0.05). The differences of measurements under relaxation and accommodation of 3D between two groups were not statistically significant (P>0.05). The decrease of anterior chamber depth and the increase of crystalline lens thickness of A group under accommodation of 6D were larger than those of B group (P<0.05), while the difference of the decrease of dark pupil diameter between two groups was not statistically significant (P>0.05). Conclusion Changes of anterior chamber depth and crystalline lens thickness in the anterior segment of eyes of children with highly myopic parents under accommodation of 6D are smaller than those of children with emmetropic parents. Whether this difference leads to the difference of refraction in the future still needs further study
ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: A preliminary study
Ming-Yii Huang, Wei-Yu Fang, Su-Chen Lee, Tian-Lu Cheng, Jaw-Yuan Wang, Shiu-Ru Lin
BMC Cancer , 2008, DOI: 10.1186/1471-2407-8-50
Abstract: Six gene polymorphisms functional in drug-metabolism – GSTP1 Ile105Val, ABCB1 Ile1145Ile, MTHFR Ala222Val, TYMS double (2R) or triple (3R) tandem repeat – and DNA-repair genes – ERCC2 Lys751Gln and XRCC1 Arg399Gln – were assessed in 201 CRC patients using a polymerase chain reaction-restriction fragment-length polymorphism (PCR-RFLP) technique and DNA sequencing. Patients were diagnosed as either high-risk stage II (T2 and 3 N0 M0) or III (any T N1 and 2 M0) and were administered adjuvant chemotherapy regimens that included 5-fluorouracil (5FU) and leucovorin (LV). The correlations between genetic polymorphisms and patient clinicopathological features and relapses were investigated.In this study, the distributions of GSTP1 (P = 0.003), ABCB1 (P = 0.001), TYMS (P < 0.0001), ERCC2 (P < 0.0001) and XRCC1 (P = 0.006) genotypes in the Asian population, with the exception of MTHFR (P = 0.081), differed significantly from their distributions in a Caucasian population. However, the unfavorable genotype ERCC2 2251A>C (P = 0.006), tumor invasion depth (P = 0.025), lymph node metastasis (P = 0.011) and cancer stage (P = 0.008) were significantly correlated with early relapse. Patients carrying the ERCC2 2251AC or2251CC genotypes had a significantly increased risk of early relapse (OR = 3.294, 95% CI, 1.272–8.532).We suggest that ERCC2 2251A>C alleles may be genetic predictors of early CRC relapse.The primary treatment for colorectal cancer (CRC) is resection of the primary tumor. After surgery, patients are frequently administered adjuvant chemotherapy to eliminate cancer cells that may have metastasized [1]. Despite chemotherapy, CRC remains the third major cause of cancer-related death in Taiwan, accounting for >3,000 deaths per year [2]. The overall five-year survival is 50–60% in European countries [3], a result similar to that in Taiwan [4]. The primary cause of death is distant and loco-regional relapses. Notably, CRC relapse is strongly correlated with chemotherapeutic
Evaluation of Cathodic Arc Deposited Thick CrAlSiN Coatings by Erosion Test  [PDF]
Wei-Yu Ho, Yen-Sho Chang, Bo-Yi Chou, Chien-Liang Lin
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.31010

CrAlSiN with thickness up to 16 μm was deposited on tungsten carbide via multi-deposition process by cathode arc deposition technique. Scratch and water-sand jet impingement erosion tests were carried out to evaluate the adhesion by determining the worn surface of the coatings. Results showed that the failure mode of the adhesion can be concluded that the weak bond of each CrAlSiN layer as compared to the strong bond between the coating and substrate. The average surface roughness of the coatings before the erosion test was about the same level. After the erosion test of 30 minutes, the eroded CrAlSiN coatings exhibited improved average surface roughness as compared to the original CrAlSiN coatings. Further increasing the erosion up to 60 minutes, the wear and minor peeling of the CrAlSiN coating between each layer was observed. A further research to improve the bond strength between each layer was needed.

Using SiO2 Nanopowders in Anode Catalyst Layer to Improve the Performance of a Proton Exchange Membrane Fuel Cell at Low Humidity  [PDF]
Chien-Liang Lin, Shih-Chieh Hsu, Wei-Yu Ho
Journal of Materials Science and Chemical Engineering (MSCE) , 2015, DOI: 10.4236/msce.2015.31011

In this study, the transfer method is employed to add hydrophilic SiO2 nanopowders to a Pt/C catalyst ink to form an anode catalyst layer on a proton exchange membrane (PEM). The SiO2-layered membrane electrode assembly improves the performance of the PEM under low- or zero-humidification conditions. When the PEM fuel cell (PEMFC) undergoes electrochemical reaction, the moisture content of the PEM exhibits a substantial influence on the transmission of protons. To ensure the moisture content remains high, an external humidifier is typically employed to humidify the majority of PEMFCs. However, self-humidifying PEMFCs could utilize the water produced by the fuel cell reaction, thereby eliminating the need for an external humidifier. In this study, various SiO2 loadings were added to an anode catalyst layer, and the cell temperature and gas humidification conditions were adjusted to determine the influence of the SiO2 loadings on the fuel cell performance. The results show that adding SiO2 is preferable to not adding SiO2 when the fuel cell temperature is 50°C.

Digital Watermarking for Error-diffused Images
Wei-yu Han,Yea-jou Shiau
Asian Journal of Information Technology , 2012,
Abstract: In this study, a new approach for watermarking of the Error-Diffused images is proposed for hiding data in halftone images. This novel data hiding is by forcing the parity on the processing pixel and preceding halftoned pixels in a unit of data either even or odd. Here, the parity used to preserve the data by means of authentication and tampering detection. The error between the original halftoned bit and parity setting bit of the current pixel is propagated to the unprocessed neighboring pixels for maintaining good visual quality. The proposed approach is directly applied to the halftoning process without extra computations. Experimental results show that the proposed method has successfully hidden the watermark into the Error-Diffused images and the results are encouraging.
Adaptive Compressive Spectrum Sensing for Wideband Cognitive Radios
Hongjian Sun,Wei-Yu Chiu,A. Nallanathan
Mathematics , 2013, DOI: 10.1109/LCOMM.2012.092812.121648
Abstract: This letter presents an adaptive spectrum sensing algorithm that detects wideband spectrum using sub-Nyquist sampling rates. By taking advantage of compressed sensing (CS), the proposed algorithm reconstructs the wideband spectrum from compressed samples. Furthermore, an l2 norm validation approach is proposed that enables cognitive radios (CRs) to automatically terminate the signal acquisition once the current spectral recovery is satisfactory, leading to enhanced CR throughput. Numerical results show that the proposed algorithm can not only shorten the spectrum sensing interval, but also improve the throughput of wideband CRs.
New algorithm for global optimization: cell membrane optimization

TAN Shi-heng,YU Wei-yu,

计算机应用研究 , 2011,
Abstract: By studying the characteristics of cell membrane and the mode of material transfer, proposed a new global optimization algorithm: cell membrane optimization (CMO), combined with global optimization algorithm. Numerical experiments proved CMO had excellent global optimization capability, rapid convergence and the ability to obtain accurate solution. Compared with the standard particle swarm optimization (PSO) and population migration algorithm (PMA). The simulation results show that CMO has better convergence performance in solving high-dimensional optimization problems.
Bee colony algorithm for image edge detection

XIAO Yong-hao,YU Wei-yu,

计算机应用研究 , 2010,
Abstract: This paper proposed an image edge detection based on bee colony algorithm. According to bee colony algorithm, could obtuin local optimization point via search image edge. Then found out object edge point from local point. Experimental results demonstrate the superior performance of the proposed approach.
Multi-level Threshold Image Segmentation Based on PSNR using Artificial Bee Colony Algorithm
Cao Yun-Fei,Xiao Yong-Hao,Yu Wei-Yu,Chen Yong-Chang
Research Journal of Applied Sciences, Engineering and Technology , 2012,
Abstract: Image segmentation is still a crucial problem in image processing. It hasn yet been solved very well. In this study, we propose a novel multi-level thresholding image segmentation method based on PSNR using artificial bee colony algorithm (ABCA). PSNR is considered as an objective function of ABCA. The multi-level thresholds (t*1, t*2 ,...., t*n-1, t*n) are those maximizing the PSNR. We compare entropy and PSNR in segmenting gray-level images. The experiments results demonstrate proposed method is effective and efficient.
Dye-Sensitized Solar Cells Using Mesocarbon Microbead-Based Counter Electrodes
Chien-Te Hsieh,Bing-Hao Yang,Wei-Yu Chen
International Journal of Photoenergy , 2012, DOI: 10.1155/2012/709581
Abstract: The dye-sensitized solar cells (DSCs) equipped with mesocarbon microbead (MCMB)-based counter electrodes were explored to examine their cell performance. Three types of nanosized additives including platinum, carbon nanotubes (CNTs), and carbon black (CB) are well dispersed and coated over microscaled MCMB powders. In the design of the counter electrodes, the MCMB graphite offers an excellent medium that allows charge transfer from the ITO substrate to the dye molecule. The active materials such as Pt, CNT, and nanosize CB act as an active site provider for the redox reaction. Among these counter electrodes, the DSCs fabricated with CB electrode exhibit the highest power conversion efficiency. This improved efficiency can be attributed to the fact that the CB nanoparticles not only offer a large number of catalytic sites but also low charge transfer resistance, facilitating a rapid reaction kinetics. Such design of carbon counter electrode has been confirmed to be a promising candidate for replacing Pt electrodes.
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