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Search Results: 1 - 10 of 111950 matches for " LML;Pay?o "
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Relationship between Helicobacter pylori detection and an increased risk of infection in childhood
Venerando, R;Rasmussen, LT;de Labio, RW;Gatti, LL;Francisco, O;Viani, GA;Rivera, LML;Payo, SLM;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2012, DOI: 10.1590/S1678-91992012000400004
Abstract: the risk of developing gastric cancer is believed to be related to differences among helicobacter pylori strains and the inflammatory responses mediated by host genetic factors. h. pylori infection is acquired at an early age and in the absence of appropriate antibiotic therapy, it generally persists for life. tp53 gene regulates the transcription of several cytokines and chemokines involved in innate immunity and its action may be influenced by the presence of different h. pylori strains. the present study aimed to detect h. pylori in pediatric patients, to access tp53 polymorphism at codon 72 and to correlate such findings with age and histopathological results. three hundred and forty-two patients were analyzed. dna from their gastric biopsies was extracted and the detection of h. pylori was performed through polymerase chain reaction assays, urease test and histopathologic examination. allelic discrimination of snp rs1042522 (tp53) was performed by real-time polymerase chain reaction. our results suggest a possible relationship between the presence of h. pylori and chronic gastritis in children and young patients, and showed a significant association between ageing and positivity for h. pylori. it was verified that patients aged < 10 years were 1.3 times more likely to have infection by h. pylori when compared with those aged > 10 years. finally, no association was found between tp53 polymorphisms and the presence of h. pylori.
Estudo rand?mico da corre??o cirúrgica do prolapso uterino através de tela sintética de polipropileno tipo I comparando histerectomia versus preserva??o uterina
Carram?o, Silvia;Auge, Antonio Pedro Flores;Pacetta, Aparecida Maria;Duarte, Eliana;Ayrosa, Paulo;Lemos, Nucélio LML;Aoki, Tsutomu;
Revista do Colégio Brasileiro de Cirurgi?es , 2009, DOI: 10.1590/S0100-69912009000100012
Abstract: objectives: to compare surgical morbidity and time, as well as anatomical outcomes between vaginal histerectomy and uterine preservation in the treatment of uterine prolapse using a mesh kit (nazca ?). methods: randomized controled trial with 31 women with uterine prolapse pop-q stage 3 or 4 pelvic organ prolapse who underwent vaginal surgery using tipe i polypropilene mesh (nazca ?). they were randomized in two groups: group hv: hysterectomy and pelvic reconstruction floor with mesh (n=15); group hp: hysteropexy and pelvic reconstruction floor with mesh (n=16). race, miccional urgency, intestinal constipation, sacral pain were assessed as well as the amount of bleeding and time of operation. results: median follow-up was nine months on both groups. no difference was observed on complication rates and functional outcomes. operation time was 120 minutes on group hv, versus 58.9 minutes on group hp (x2 = 17.613*, p < 0.001 ) and intraoperative blood loss was 120 ml on group hv versus 20 ml on group hp (x2 = 19.425*; p < 0.001). there was no differences in relationship to anatomical cure rates. objective success rate was 86.67% to group hv and 75% to group hp (p=0,667) at nine months of follow-up. the anatomical results were similar between the two groups. conclusion: the anatomic results between histeropexy and hysterectomy were similar. however, surgical time and blood loss were greater in group with histerectomies. the erosion rate were also similar. vaginal surgery using mesh is an effective procedure for pelvic organ prolapse.
COMPARATIVE ANALYSIS OF PERFORMANCE OF PORTLAND CEMENT BLENDED WITH NANOSILICA AND SILICA FUME
TOBóN,J. I; RESTREPO,O. J; PAYá,J;
DYNA , 2010,
Abstract: in this paper some physical properties of colombian portland cement type iii replaced with nanosilica in percentages of 1, 3, 5 and 10% were evaluated. main determined properties were fluidity, normal consistency, setting times, heat of hydration and compressive strength on pastes and mortars. it was made also a comparative analysis with samples substituted with commercial silica fume in percentages of 5, 10 and 15%. results showed that the nanosilica from 5% beginning to have a major positive influence on the mechanical strength of mortars and with a 10% of substitution improvements in compressive strength up to 120% with respect to the control sample for one day of curing can be achieved. for longer curing time the improvement is decreased slightly, with near 80%, remaining this improvement in strength after 28 days of curing.
Controle genético das células-tronco humanas cultivadas
Payo, Spencer L. M.;Segato, Rosimeire;Santos, Ricardo R.;
Revista Brasileira de Hematologia e Hemoterapia , 2009, DOI: 10.1590/S1516-84842009005000021
Abstract: stem cells have a high capacity of self-regeneration, as well as a potential to differentiate into several cell types. these cells can be classified as embryonic or adult. in spite of having inherent properties of stem cells, mesenchymal cells show a certain degree of difficulty to establish cultures. this might induce a loss of the expression of the telomerase enzyme which is considered to be a biological clock or an indicator of the senescence of the cells. the most current and intriguing question for researchers is whether the presumed division potential of cultivated stem cells, over a period of time could result in an accumulation of genetic alterations and consequently, in a neoplastic process. for this reason, cytogenetic techniques are very important to guarantee the control and safety of cultivated stem cells to be used in human therapy. structural chromosomal alterations, such as for example, deletions, translocations and inversions represent an important mechanism by which cells might gradually transform in a neoplastic process. thus, these chromosomal alterations could result in an abnormal expression of the genes and lead to cancer.
Características clínicas da apraxia de fala na infancia: revis o de literatura = Clinical characteristics of childhood apraxia of speech: literature review
Payo, Luzia Miscow da Cruz et al.
Letras de Hoje , 2012,
Abstract: A falta de precis o e consistência dos movimentos de fala na ausência de déficits neuromusculares s o características de quadros de apraxia. A altera o ocorre no planejamento e/ou programa o de parametros espa o-temporais das sequências dos movimentos, resultando em erros na produ o dos sons da fala e altera es prosódicas. Essa revis o de literatura pretende abordar a produ o normal do gesto articulatório no contexto da fala encadeada, semelhan as e diferen as entre a apraxia de fala na infancia e a apraxia adquirida no adulto, além de características encontradas na literatura que auxiliam no diagnóstico da apraxia infantil. Os quadros de apraxia em adultos, ao contrário dos infantis, correspondem a uma perda de fun o neurológica. Em crian as, essa desordem prejudica o desenvolvimento de fun es que est o em processo de aquisi o. The lack of accuracy and consistency of speech movements in the absence of neuromuscular deficits are characteristic of apraxia. The alteration occurs in the planning and/or programming spatiotemporal of sequence movements parameters resulting in errors in the speech sounds production and prosodic disorders. This literature review aims to address the normal production of the articulatory gesture in the context of linked speech, similarities and differences between childhood apraxia of speech and acquired apraxia in adults, and features found in the literature that support the diagnosis of childhood apraxia. Unlike in children, apraxia in adults corresponds to loss of a neurological function. This disorder, in children, impairs the development of functions that are in acquisition.
COMPARATIVE ANALYSIS OF PERFORMANCE OF PORTLAND CEMENT BLENDED WITH NANOSILICA AND SILICA FUME
J. I TOBóN,O. J RESTREPO,J. PAYá
DYNA , 2010,
Abstract: In this paper some physical properties of Colombian Portland cement type III replaced with nanosilica in percentages of 1, 3, 5 and 10% were evaluated. Main determined properties were fluidity, normal consistency, setting times, heat of hydration and compressive strength on pastes and mortars. It was made also a comparative analysis with samples substituted with commercial silica fume in percentages of 5, 10 and 15%. Results showed that the nanosilica from 5% beginning to have a major positive influence on the mechanical strength of mortars and with a 10% of substitution improvements in compressive strength up to 120% with respect to the control sample for one day of curing can be achieved. For longer curing time the improvement is decreased slightly, with near 80%, remaining this improvement in strength after 28 days of curing.
BLMH and APOE genes in Alzheimer Disease: A possible relation  [PDF]
J. P. B. Ximenez, L. T. Rasmussen, W. A. Orcini, R. W. Labio, G. V. Arruda, P. H. F. Bertolucci, M. A. Smith, S. L. M. Payo
Advances in Alzheimer's Disease (AAD) , 2013, DOI: 10.4236/aad.2013.23015
Abstract: Alzheimer disease (AD) is a progressive and irreversible neurodegenerative disorder that is characterized by cognitive decline, memory loss and confusion. The E4 allele of the apolipoprotein E gene (APOE) is associated with AD and it is the main genetic risk factor for disease. Although the exact physiological function is unknown, bleomycin hydrolase (BLMH) may also be associated with AD development, although previous immunohistochemical findings havebeen inconsistent. Therefore, the purpose ofthis study was to evaluate the genotypic and allele frequencies of theAPOEgene andBLMH1450 G> A polymorphism and assessBLMHexpression using PCR-RFLP and RT-qPCR analyses ofblood samples from patients with Alzheimer disease (AD), healthy elderly adults (EC) andhealthyyoung subjects(YC). BLMHexpression wassignificantly different among groups (p= 0.015) and there was substantial reduction with age and with AD. TheAPOEandBLMHgenotype frequency did not diverge from the Hardy-Weinberg equilibrium. There was a higher frequency of genotype 3/3 inall subjects (61.1%) and the AD group demonstrated a higher frequency of allele 4; however, differences ingenotype and allele distributions were statistically different among groups.

Prevalence of Helicobacter pylori cagA and sabA Genotypes in Patients with Gastric Disease  [PDF]
Jéssica Nunes Pereira, Wilson A. Orcini, Rita L. Peruquetti, Marilia A. C. Smith, Spencer L. M. Payo, Lucas T. Rasmussen
Advances in Microbiology (AiM) , 2019, DOI: 10.4236/aim.2019.93017
Abstract: Gastric cancer is one of the most common types of cancer worldwide. Helicobacter pylori is considered one of the most important causes of this condition specially because of its virulence markers as sabA and cagA. Therefore, we aim to investigate the relation between these markers and the gastric diseases in 400 patients who underwent upper digestive endoscopy. To detect the bacteria and its genes by Polymerase Chain Reaction (PCR), the presence of H. pylori was significant when comparing the groups control vs. cancer (p value < 0.0001) OR [95% CI] 12.73 (5.45 - 29.69) and the groups control vs. chronic gastritis (p value < 0.0001) OR [95% CI] 12.99 (7.44 - 22.66). cagA was statistically significant considering its presence when comparing the chronic gastritis vs. cancer groups (p value = 0.0434) OR [95% CI] 2.44 (1.021 - 5.845). Associating both sabA and cagA, we found a statistically significant result (p value < 0.0001) OR [95% CI] 13.68 (3.95 - 47.33) considering the gastritis vs. cancer groups. Helicobacter pylori is directly associated to gastric diseases such as gastritis and cancer and its virulence markers: sabA and cagA increase the injury process to the gastric epithelium making the host more susceptible to cancer.
Los pueblos del salitre The villages of niter
Ernesto Payá
Revista chilena de infectología , 2012,
Abstract:
La pintura histórica The historical painting
Ernesto Payá
Revista chilena de infectología , 2013,
Abstract:
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