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Search Results: 1 - 10 of 593350 matches for " L.A.; "
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Problem based learning: From artificial heresy to res popularis
Branda,L.A.;
Educación Médica , 2009, DOI: 10.4321/S1575-18132009000100004
Abstract: the vast use of problem based learning (pbl) in the teaching-learning process has resulted in its transformation from an artificial heresy to a res popularis with the subsequent proliferation of publications, books and congresses on the subject. this deluge of information, very often, has created confusion on the comprehension of what pbl is as learning strategy. this article presents a definition of what pbl was considered in its conception, and its extension to problem resolution. the importance of learning objectives (learning outcomes) is indicated and some steps in the preparation of situations/scenarios/problems/cases are described. also, student evaluation is described, both the formative evaluation based on tutorial observations as well as the summative. the description of the stages in the pbl process has solely the purpose to indicate what the students could do, not what they should do. taking into account the resource limitations of most institutions which wish to implement pbl, the application of this strategy in large groups is also described. the role of the tutor facilitator and the characteristics of his intervention from hierarchical to one of facilitating student autonomy are discussed. this article ends with a reflexion on self-directed learning and its relationship to self-regulated learning.
Período crítico de interferência das plantas daninhas na cultura do milho baseado na fenologia da cultura
Kozlowski, L.A.;
Planta Daninha , 2002, DOI: 10.1590/S0100-83582002000300006
Abstract: a field experiment was carried out to determine the critical period of weed interference in corn, under a no-tillage system, based on the phenological stage of corn crop growth, at the gralha azul experimental farm/puc pr - brazil, during the growing season of 2000/2001. the experimental design was a randomized complete block arranged in a 2x7 factorial, with four replications. the fourteen treatments evaluated resulted from two series of treatments: with the crop weed free during the initial crop development and with the crop weedy during the initial crop development, in five phenological stages of corn crop growth: v2, v4, v6, v8 and v10 and two checks. the experiment was carried out on an area under no-till system. seeding, fertilization, and insect and disease control were conducted according to crop technology. weed interference critical period was between v2 and v7 phenological stages of growth, and corn yield was reduced in 87% when the crop was kept weedy during all the cycle, compared to the weed free crop. the dicotyledon species represented 22.3% of the community, with taraxacum officinale, senecio brasiliensis, rumex obtusifolius and bidens pilosa being most prevalent. monocotyledons species represented 77.7%, and brachiaria plantaginea was the most prevalent. biomass accumulation of corn, final population and ear per plant were not affected by weed interference.
The Significance of Laboratory Indices to Determine the Number of Lesions in Patients with Non-muscle Invasive Urinary Bladder Cancer
L.A. Derzhavets
Sovremennye Tehnologii v Medicine , 2012,
Abstract: The aim of the investigation is to estimate laboratory indices to determine the number of lesions in patients with non-muscle invasive urinary bladder cancer. Materials and methods. There were studied 552 patients with non-muscle invasive urinary bladder cancer, who had been treated in Republic Scientific Practical Centre of Oncology and Medical Radiology named after N.N. Alexandrov in 2002–2010 (Republic of Belarus). Modern laboratory techniques (immunoenzyme, immunoturbidity method, spectrofluorometry, ozonation, electron paramagnetic resonance spectrometry) were used to study tumour markers, growth factors, angiogenesis, cell-cell adhesion, endothelial damage, the products of inflammation and oxidative modifications of proteins and lipids in biological fluids (blood serum and plasma, urine). The investigation had been carried out before special treatment was started. The patients were divided into two groups depending on the number of lesions (266 patients with a single mass lesion, and 286 — with multiple mass lesions). Results. Statistical analysis of the data obtained enabled to reveal four indices from 27 studied parameters (Urinary Bladder Cancer — UBC, Tissue Polypeptide Antigen Specific — TPS, Intercellular Adhesion Molecule — sICAM, Transmembrane HER2-neu receptor — p185) correlating maximally with the number of lesions and minimally — among themselves, and form two regression equations on their basis. The equations make it possible to determine the presence of multiple mass lesions in patients with non-muscle invasive urinary bladder cancer preoperatively, the sensitivity of equations being 81–84%. Thus, clinicians can carry out an additional thorough examination of a patient (photodynamic diagnosis) in due time in order to reveal multifocal tumour growth.
“New economy” and innovative development
L.A. Yaremko
Marketing ì Mened?ment Innovacìj , 2011,
Abstract:
Mechanism of estimation of marketing strategy
L.A. Kvyatkovska
Marketing ì Mened?ment Innovacìj , 2011,
Abstract: In the article the chart of base elements of forming of marketing strategy of enterprise is given and indexes which can be applied at the estimation of efficiency of its realization within the limits of the models known broadly speaking are determined.
Dependence of central hemodynamic parameters on anthropo-somatotypologic peculiarities in ecto-morphic somatotype adolescence
Sarafinyuk L.A.
Морфолог?я , 2012,
Abstract: The article presents the results of construction of the regression models of reographic central hemodynamic parameters on the basis of anthropometric and somatotypological indexes features for practically healthy municipal youth boys and girls ectomorphic somatotype in Ukraine, Podolsk region. For boys with ektomorfs somatotype was found more symptoms according to which the final variant of regressional polynom has a coefficient of determination above 0.50. We have built mathematical models for boys with ektomorfs somatotype for the ten indicators of central hemodynamics, for the girls of the same constitutional type - for five only. Models of reographic central hemodynamic parameters of young men with ectomorphic somatotype often includes suchanthropometric dimensions: thickness of skin and fat folds on the abdomen, the circumference of the chest on inspiration and the face width. For the girls with ectomorphic somatotype in most cases the variability of central hemodynamics parameters determines by skin-fat folds thickness on shin and abdomen.
Modification of the protein’s composition from the neurospecifical intermediate filaments in different parts of the red’s brain depend on actions of the ionisition radiation
Romanenko L.A.
Морфолог?я , 2008,
Abstract: In our work was spend the research about modification of the protein’s composition from the neurospecifical intermediate filaments in different parts of the red’s brain, which depend on duration actions of the ionisition radiation. To the research traded on 30 reds. It were devided on groups, which depend on fate of radiation – 1 day, 1,2 and 3 week, like the control group. We spending the Rh – irradiation on the putting RUM – 17 in the fate 0,00129 Kl/kg. We was devide the brain on parts ( there are: the cortex, the cerebellum, the gypocamp), homogenize, centrifugize. Nhe quantity of neurofilaments (NF) was defined by the rocket-lineal immunoelectrophoresis. We defined reliable changes of the neurofilaments’s support in aii groups, which was expose by the action of small – fate ionisition radiation. The character of manifestations from this changes determined by the fate of action. So, the support of the protein NF at the experimental reds was not practically differ of control group by the unitary irradiation. The extension of the quantity of neurofilaments was set in the cortex of greater hemispheres, the cerebellum, the gypocamp at the irradiation reds during 21 days. We colligated this changes with polypep-tide 210 kDa.
The influence of small dozes of ionizing radiations on a glial intermediate filament’s condition.
Romanenko L.A.
Морфолог?я , 2007,
Abstract: The purpose of research was to define changes of structure of glial intermediate filaments in different departments of a brain of rats, depending on term of an irradiation. For research 30 rats that have been divided into groups have been used, depending on term of an irradiation - 1 day, 1, 2 and 3 weeks, including control group. The x-ray irradiation was spent on installation РУМ-17 in a doze of 0, 0129 Kl/kg. A brain divided on departments (a bark of the big hemispheres, a cerebellum, and gypocampus), homogenizing, and centrifugation. Quantity glial and fibrillar sour fiber (GFSF) defined with the help rocket – linear electrophoresis. Under action ionizing low-dose radiations by us have been determined authentic changes of contents GFSF in all groups subjected to an irradiation. Intensity these changes revealed dependence on validity of radiation. Character of these changes in researched departments of a brain was identical. Change of the contents of soluble and sour form GFSF were independent from each other. Thus, the unitary irradiation during 7 day caused decrease in both fractions GFSF in gypocampus and a cerebellum while in a bark of the big hemispheres increase filaments fractions took place within the limits of 5-23 %. The irradiation during 14-21 day was accompanied by increase filaments forms GFSF in researched structures of a brain.
Age features in protein’s composition modifications of the neurospecifical and glial intermediate filaments in different parts of the red’s brain depend on ionization radiation actions
Romanenko L.A.
Морфолог?я , 2008,
Abstract: In this work we compare the main changes in protein composition of intermediate filaments due to ionization radiation actions on old and yang rats. The objects of our investigation were 120 rats (60 old and 60 yangs). They were divided on groups in depend on ionization radiation action duration – 1 day, 1,2 and 3 week, and the control group. The action of ionization radiation was modeled with the help of “РУМ-17” in the fate 0,00129 Kl/kg. Brains were divided on parts (cortex, cerebellum, gypocamp), homogenized, centrifugised. The quantity of glial and neuronal filaments (NF) was defined by the rocket-lineal immunoelectrophoresis; immunoblotting with specific antibodies was used for qualitative changes defining. After ionization radiation action we observed no age features in protein composition of intermediate filaments. All changes were due to duration of the ionization radiation action. Main changes in neurofilaments were associated with decrease of 210 kDa subunit. Products of degradation (40 - 48 kDa) of fibrillar glial filaments were observed on the 2 week of experiment. There were biphasic changes in glial fibrillar acidic protein in cerebellum and gypocamp of yang and old rats.
Efficacy and safety of fixed combination of lisinopril and hydrochlorothiazide for management of vascular disorders in patients with arterial hypertension
L.A. Haisheva
Rational Pharmacotherapy in Cardiology , 2009,
Abstract: Aim. To study endothelial disorders and artery elasticity disorders in patients with arterial hypertension (HT), as well as possibility of their correction by lisinopril or by fixed low dose combination of lisinopril and hydrochlorothiazide.Material and methods. 99 patients with HT were included in the study. Patients were randomized into 2 groups. Patients of the 1st group were treated with the fixed low dose combination of lisinopril (5мг) and hydrochlorothiazide (12,5 mg). Patients of the 2nd group were treated with lisinopril alone. The amlodipine was added in case of insufficient therapy. Pulse wave velocity was defined by volume sphygmography. Tests for evaluation of microalbuminuria and activity of von Willebrand factor were performed.Results. Endothelium function disorders were observed in a half of the patients with HT aged 60 y.o. and older. The fixed low dose combination of lisinopril and hydrochlorothiazide was more effective than lisinopril monotherapy in target blood pressure achievement. Positive changes of endothelium function indicators were founded in both groups of therapy. This fixed combination had also a good safety profile.Conclusion. Lisinopril alone or in low dose combination with hydrochlorothiazide improves endothelium function and decreases microalbuminuria level in patients with HT and high body mass index.
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