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Search Results: 1 - 10 of 378122 matches for " Lívia Cristina de Melo Pino "
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Evaluation of the Therapeutic Response and Improvement in the Quality of Life of the Patient with Darier Disease to Acitretin through an Analogy between Close Relatives  [PDF]
Thiago Sande Miguel, Mateus de Oliveira Reis, Bruno Fonseca dos Santos, Aline da Silva Rocha, Nayrton Kalys Cruz dos Anjos, Lívia Cristina de Melo Pino, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.58004
Abstract: Darier disease (DD), also known as follicular keratosis, is a rare autosomal dominant hereditary acantholytic dermatosis caused by a mutation in the ATP2A2 gene. Skin lesions are characterized by persistent confluent papules, preferentially located on the seborrheic areas of the face, chest and back. The hands, feet and nails are also commonly affected. DD has a chronic course with frequent relapses. Their treatment is often difficult and unsatisfactory. We present the case of a 54-year-old male with a history of keratotic papules with a brownish-black color, with a foul-smelling, pruritic and ardent appearance on the back and trunk, since the age of 19, which worsen in the summer. His 27-year-old daughter has a similar picture with her skin lesions started at age of 17 in the region below the breast, back, trunk, feet and hands. After the skin biopsy, the diagnosis was confirmed and acitretin 30 mg/day was instituted. The importance of this case report is to alert health professionals that the diagnosis of DD should be considered in family members of patients, especially those in the first degree, and also in patients with follicular keratolytic dermatoses, being an important differential diagnosis of this group of patients diseases.
Cutaneous Vasculitis with Renal Impairment in Octogenarian  [PDF]
Thiago Sande Miguel, Bruna Sande Miguel, Vinicius Sande Miguel, Jair Baptista Miguel, Sebasti?o Celio Horta Coelho Filho, Nayrton Kalys Cruz dos Anjos, Lívia Cristina de Melo Pino, Paola Stephanie Azevedo de, Vitor Araújo Goulart, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.56004
Abstract: Henoch-Schönlein purpura is a vasculitis of small vessels, characterized by tissue deposition of IgA, affecting predominantly the skin, intestine, joints and kidneys. It mainly affects the pediatric age group, especially from 2 to 11 years old. Most often, it is preceded by episode of upper airway infection from days to weeks. The most common clinical manifestations are purpuric cutaneous lesions located in the lower limbs and buttocks, abdominal pain in colic, nausea, vomiting, diarrhea, in addition to arthralgia/arthritis, usually with spontaneous resolution. Renal impairment usually manifests with hematuria and proteinuria, and renal function may also be impaired. The case described refers to a female patient, 86 years old, with a previous history of infection of the upper airways, followed by purpura in the lower limbs and renal impairment: serum creatinine 3.1 mg/dL (N 0.5 - 1.2 mg/dL); glomerular filtration rate 15 ml/min (N > 60 ml/min); urea 118 mg/dL (N < 40 g/dL); proteinuria 4.497 mg/24h. The present report aims to draw attention to the occurrence of Henoch-Schönlein purpura in an atypical age group, with significant renal impairment, improvement only with conservative treatment, thus avoiding the use of immunosuppressants and the risks of immunosuppression and toxicity related to such drugs.
Ulcerated Lesion in Buccal Mucosa in a Patient with Paracoccidioidomycosis—Case Report  [PDF]
Giovanna Lima Vaz, Lívia Cristina de Melo Pino, Aline Gabriela Santos Costa, Ibrahim Yahia El Somailli, Jo?o Roberto Resende Fernandes, Elayne Christina Meireles Martins, Daniel Cohen Goldemberg, Aline Hellen da Silva Camacho, Rhanna Neves Cirqueira, Daniel Almeida da Costa
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.510005
Abstract: Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is a fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis. This microorganism can penetrate the human body through direct contact and can cause intense lymphadenopathy, ulcerated lesions in the oral cavity and in the skin among other alterations. In this study, we report a case of paracoccidioidomycosis with unusual clinical presentation, as it manifested in the female sex and although it did not present any relevant complaints of respiratory focus, it presented a single ulcerated lesion in the buccal mucosa. A biopsy of the lesion and a mycological examination revealed Paracoccidioidesbrasiliensis infection.
Nodular Amyloidosis Overlapping and Polymyositis in a Patient with Skin Manifestations Lupus Fax: Case Report  [PDF]
Enéas Van Der Maas do Bem Filho, Laíza Maria dos Santos Couto, Ant?nio Luiz da Costa Soares Jr., Pedro Paulo Andrade, Thiago Sande Miguel, Sebasti?o Célio Horta Coelho Filho, Daniel Almeida da Costa, Lívia Cristina de Melo Pino, Thayro Van Der Maas do Bem
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.511005
Abstract: Amyloidosis is the result of fibrous and insoluble amyloid protein deposition in extracellular spaces of tissues and organs, including the skin. Through the analysis of medical records, clinical condition and laboratory tests, this article proposes a rare case report of an adult patient with symptoms and diagnosis of polymyositis, histopathology of nodular amyloidosis with skin lesions suggestive of lupus. The patient is still being followed at the dermatology clinic of Valença Medical School, in order to improve the prognosis and prevent the progression of existing symptoms.
Valores de referência de qualidade para metais pesados em solos no Estado do Espírito Santo
Paye, Henrique de Sá;Mello, Jaime Wilson Vargas de;Abrah?o, Walter Ant?nio Pereira;Fernandes Filho, Elpídio Inácio;Dias, Lívia Cristina Pinto;Castro, Maria Luisa Oliveira;Melo, Stefeson Bezerra de;Fran?a, Michele Milanez;
Revista Brasileira de Ciência do Solo , 2010, DOI: 10.1590/S0100-06832010000600028
Abstract: the reference quality values (rqv) for heavy metals in soils are quite heterogeneous around the world. in brazil, few studies establishing such values have been published. in the absence of vrq of heavy metals in soils established for the specific conditions of the state of espírito santo, international generic values or values developed for other states are used. however, it should be noted that the use of these values can lead to erroneous assessments, due to the regional differences in technical and environmental variables, particularly in terms of geological, water and soil conditions. the purpose of this study was to determine heavy metal concentration in soils of espírito santo state, and to investigate the major factors involved in the distribution of as, cd, co, cr, cu, mn, mo, ni, pb, ti, v and zn in soils of the river basins of riacho, reis magos and santa maria da vitória. based on this information rqv were established. total concentrations were determined by microwave oven digestion, according to the sw-846 3052 method of the environmental protection agency (usepa), and by inductively coupled plasma optical emission spectrometer (icp-oes). the mean concentrations of most heavy metals studied were, in general, lower than reported in international references. cadmium concentrations were below the detection limit (dl) in all samples. the rqvs found from the percentile 75 for as (< 12.83), cd (< 0.13), co (10.21), cr (54.13), cu (5.91), mn (137.80), mo (1.74), ni (9.17), pb (< 4.54), v (109.96), and zn (29.87), in mg kg-1; were similar to or lower than those adopted in sao paulo state and in brazilian, in general.
Relatório de estágio supervisionado como gênero discursivo mediador da forma??o do professor de língua materna
Silva, Wagner Rodrigues;Melo, Lívia Chaves de;
Trabalhos em Linguística Aplicada , 2008, DOI: 10.1590/S0103-18132008000100008
Abstract: this paper proposes to investigate the teacher process of education and the construction of teaching object on subjects of pre-service teacher of mother language teaching. the investigation is made through documental analysis of final report made by trainee teachers on the mentioned subjects. the final reports are shaped as a discursive genre so instable and complex what is triggered by the mobilization of different teacher knowledge that leads the professional practice of the trainee teacher. the results show the necessity of constant investigation or reflection about the teacher action. the transdisciplinar perspective of the applied linguistic is adopted on this paper.
Elementos traqueais de cinco táxons de Cactaceae da caatinga pernambucana, Brasil
Arruda, Emília Cristina Pereira de;Alves, Marccus;Melo-de-Pinna, Gladys Flávia;
Acta Botanica Brasilica , 2004, DOI: 10.1590/S0102-33062004000400004
Abstract: this work brings a morphological characterization of traqueary elements (vessels and tracheids) in root and cladode of five taxons of cactaceae (harrisia adscendens (gurke) britton & rose, melocactus × horridus wedermann notizbl., m. zehntneri (britton & rose) luetzelb., tacinga inamoena (schumann) n.p. taylor & stuppy and t. palmadora (britton & rose) n.p. taylor & stuppy) occurent in the caatinga of pernambuco state, brazil. the vessels elements observed in the roots and cladodes seem almost same among the studied taxons, were observed alternate, opposite and scalariform pitting, and simple perforation plate transversal or oblique. the tracheids (wbt) were exclusively noted in the cladodes of four studied taxons, except harrisia adscendens. the wbts with annular and helical thickening are present in all taxons and the mix thickening is present only in melocactus. the vessel elements and tracheids were measured and showing that the vessel elements are longer in roots and cladodes of melocactus and the longest wbts were only observed in cladode of melocactus.
Subacute Cutaneous Lupus Erythematosus in Older Man: Case Report  [PDF]
Debora Trindade Martins, Thiago Sande Miguel, Nayrton Kalys Cruz dos Anjos, Sebasti?o Celio Horta Coelho Filho, Vinicius Moreira Paladino, Bruna Sande Miguel, Vinicius Sande Miguel, Daniel Almeida da Costa, Livia Cristina de Melo Pino
Journal of Biosciences and Medicines (JBM) , 2017, DOI: 10.4236/jbm.2017.510003
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that affects mainly women, presents several clinical manifestations and has no known exact cause. The skin is one of the organs that can be affected, with subacute cutaneous lupus erythematosus (SCLE) being one of the classifications according to cutaneous lupus erythematosus lesions. SCLE is commonly found in young to middle age women and carries characteristics related to sun exposure. In this report, there is a rare case of a male and elderly patient that presents SCLE subgroup initially asymptomatic, with subsequent appearance of macular skin lesions and vitiligo appearance. This is an important case to alert health professionals that the disease can manifest itself and open its clinical profile even in patients of sex and unusual ages.
Correlations between yield and fruit quality characteristics of fresh market tomatoes
Souza, Lívia M de;Melo, Paulo César T;Luders, Reginaldo R;Melo, Arlete MT;
Horticultura Brasileira , 2012, DOI: 10.1590/S0102-05362012000400011
Abstract: genotypic, phenotypic and environmental correlations were estimated for all possible pairs among eleven characters of tomatoes. fifteen treatments including five parents and ten hybrids of instituto agron?mico (iac) tomato breeding program were evaluated using a randomized complete block experimental design, with tree replications in itatiba, s?o paulo state, brazil, during 2005/2006. the following traits were evaluated: fruit yield per plant (fp), fruit number per plant (fn), average fruit weight (fw), cluster number per plant (cn), fruit number per cluster (fc), number of locules per fruit (nl), fruit length (fl), fruit width (wi), fruit wall thickness (ft), total soluble solids (ss), and total titratable acidity (ta). the genotypic (rg), phenotypic (rf) and environmental correlations (ra) for two pairs of plant traits were estimated using the genes? program. high similarity was found among the estimates of genotypic and phenotypic correlations. positive and high phenotypic and genotypic correlations were observed between fp and the traits fn, fw and ft, and these associations contributed for yield increasing. fw and ft contributed to yield increase and should be considered together as primary yield components in tomato. positive values of the genotypic and phenotypic correlations revealed that fp influenced fn with high direct effect and significant positive correlation. these traits may be included as the main selection criteria for tomato yield improvement.
Topotecan Use for Second-Line Treatment in Patients with Recurrent or Metastatic Cervical Cancer at Brazilian National Cancer Institute (INCA)  [PDF]
Leandro Nascimento de Oliveira, Flávia Vieira Guerra Alves, Paulo Alexandre Ribeiro Mora, Claudio Calazan do Carmo, Angélica Nogueira-Rodrigues, Alvaro Henrique Ingles Garces, Andréia Cristina de Melo
Journal of Cancer Therapy (JCT) , 2013, DOI: 10.4236/jct.2013.46126

Objective: Cervical cancer represents the third most commonly diagnosed cancer and is an important cause of death for women suffering with malignancies. Patients who are refractory or progressed after first-line palliative treatment have a dismal prognosis and no second-line chemotherapy is considered standard so far. Several agents have been investigated in this setting and topotecan is one of the most characterized. The objective of this study was to evaluate response rate (RR), progression-free survival (PFS), overall survival (OS) and toxicity of topotecan in second palliative line for cervical cancer. Methods: An analysis was performed of all patients with recurrent or metastatic cervical cancer treated with topotecan in second palliative line at Brazilian National Cancer Institute, between 2008 and 2010. Results: A total of 73 courses of topotecan were given in the current study (median: 3.5 cycles; range 1 - 6). Anemia was the most frequent adverse event (grade 2:35%; grade 3:30%). Of the 20 patients evaluable, there were 2 partial responders to the treatment. The overall response rate (ORR) was 10%; 3 patients (15%) had stable disease as maximum response. The median PFS for the entire group was 2.93 months (95% CI 2.41 - 3.45) and OS was 4.66 months (95% CI 1.21 - 8.11). Conclusion: The limited activity of topotecan schemas in second-line treatment of cervical cancer and the associated overall toxicity may not justify their use in this setting. Patients who progress after first-line treatment may be offered participation in clinical trials, other second-line agents or best supportive care measures.

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