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Search Results: 1 - 10 of 217631 matches for " Lígia Fernandes "
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A Rare Case of Pulmonary Mucormycosis Successfully Treated with Dual Antifungal Agents and Surgery in a Patient with Uncontrolled Diabetes  [PDF]
Vera Clérigo, Lígia Fernandes, Tiago Abreu, Pedro Barradas
Open Journal of Respiratory Diseases (OJRD) , 2016, DOI: 10.4236/ojrd.2016.62005
Abstract: Pulmonary mucormycosis is an emergent and life-threatening invasive fungal infection underdiagnosed by clinicians due to unspecific clinical picture and lack of awareness. Although the acknowledgment of risk factors, clinical and radiological findings may increase early recognition, the definite diagnosis is challenging to establish and the ideal treatment has never been delineated. The authors describe a rare case of pulmonary mucormycosis that was successfully treated with dual antifungal treatment and surgery in a patient with uncontrolled diabetes. When last evaluated, he was asymptomatic with no evidence of relapse. To our knowledge this is a rare report of a successfully treated diabetic patient with pulmonary mucormycosis with L-AmB, triazole posaconazole and surgery with no evidence of recurrence. We highlight the importance of clinicians’ awareness to early diagnosis, combined antifungal treatment and adjuvant surgery as the greatest chance of cure of a rapidly progressive disease with high mortality and morbidity.
A Rare Case of Diaphragmatic Mass: The Key to Diagnosis of a Lung Adenocarcinoma  [PDF]
Cláudia Rocha, Vera Clérigo, Lígia Fernandes, André Rodrigues, Dora Sargento, Glória Silva
Advances in Lung Cancer (ALC) , 2014, DOI: 10.4236/alc.2014.33009
Abstract: Lung cancer is a leading cause of death due to malignancy worldwide. Diaphragmatic metastasis secondary to primary lung cancer is rare. In the literature, only a few cases have been described as the majority of cases of diaphragmatic metastasis which are secondary to gastrointestinal neoplasia. The authors report a rare case of diaphragmmatic metastasis from a primary adenocarcinoma of the lung in a 76-year-old female patient with no history of active or passive smoking with progressive worsening fatigue, asthenia, malaise, and unquantified weight loss with three months of evolution, associated with pleuritic chest pain and edema of the lower limbs for fifteen days previous to hospital admission. Chest X-ray showed elevation of the right hemi-diaphragm and thoracic-abdominal-pelvic computed tomography revealed a complex multilobuled mass with neoformative characteristics intersecting the diaphragm and invading the dome liver and the right lung region. Biopsy of the mass was performed whose histological examination was consistent with moderately differentiated adenocarcinoma. Immunohistochemical examination was positive for cytokeratin 7 and negative forcytokeratin 20, suggesting primary lung tumor. A positron emission tomography was performed without uptake in other locations. Diagnosis of adenocarcinoma with diaphragmatic metastasis was then admitted and the patient started chemotherapy with carboplatin and gemcitabine. The patient died six months after the diagnosis. The authors also present a brief theoretical discussion based on the current and scarce literature on this rare entity.
Infective Endocarditis with Negative Cultures: A Defiant Diagnosis  [PDF]
Cláudia Rocha, Vera Clérigo, Lígia Fernandes, André Rodrigues, Dora Sargento, Glória Silva
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.38101

The diagnosis and management of blood culture-negative endocarditis constitute a real clinical challenge and a systemic approach is necessary for a successful outcome. The authors report a case of a female patient aged 26, with previous clinical history of valve disease and heart failure NYHA class II, with decompensation of co-morbidities associated with fever, productive cough, nonselective anorexia and unquantified weight loss with one month of evolution with negative blood cultures. Transesophageal echocardiography revealed the presence of severe pulmonary hypertension and mitral valve vegetations in the context of positive serology for Q fever. Herein, the authors report a case of blood culture-negative endocarditis and present a brief review on the management of this medical condition. We highlighted the diagnostic difficulties of blood culture-negative endocarditis and subacute clinical presentation, which sometimes present with fever of unknown origin and complaints of deterioration of cardiac function, thus creating a challenging differential diagnosis.

Gangrenous Cholecystitis with Atypical Presentation in an Elderly Diabetic Woman  [PDF]
Vera Clérigo, Cláudia Rocha, André Rodrigues, Lígia Fernandes, Dora Sargento, Glória Silva
Case Reports in Clinical Medicine (CRCM) , 2014, DOI: 10.4236/crcm.2014.39110

In elderly patients, numerous factors subsidize the diagnostic challenge and high incidence of complications in this specific population, taking gangrenous cholecystitis as a critical example. The aim of this work is to report an unusual case of gangrenous choleystitis in an elderly diabetic women and its atypical clinical presentation. A 79-year-old female patient came to our observation; her medical history showed nausea and vomiting of about 2 hours which rapidly ended with symptomatic therapy, without recurrence, and a 3-week history of intermittent fever associated with productive cough. No abdominal discomfort was declared. Physical examination of the abdomen was negative. Laboratory analysis revealed leukocytosis with the remaining criteria within the normal range. After 2 days, she started with a mildabdominal pain in the epigastric region that rapidly progressed to the right upper quadrant, right flank and right iliac fossa, without nausea, vomiting or fever. Abdominal computer tomography findings revealed thickness of the gall-bladder and important densification of the vascular bed. Acute cholecystitis was diagnosed. The patient was then submitted to a laparoscopic cholecystectomy under general anaesthesia with findings suggestive of gangrenous acute cholecystitis confirmed by histologic examination of the specimen. Delays in diagnosing acute cholecystitis in specific populations, such as elderly diabetics, result in a higher prevalence of morbidity and mortality due to potentially serious complications as gangrenous cholecystitis. Consequently, the diagnosis should be measured and investigated promptly in order to prevent poor outcomes.

Swimming Heart: A Pleural, Pulmonary and Pericardial Disseminated Thymoma  [PDF]
Lígia Fernandes, André Rodrigues, Vera Clérigo, Cláudia Rocha, Dora Sargento, Glória Silva
Open Journal of Clinical Diagnostics (OJCD) , 2014, DOI: 10.4236/ojcd.2014.44030
Abstract: Thymoma is the most common neoplasm of the anterior mediastinum and accounts for one quarter of all mediastinal tumours and half of all anterior mediastinal masses. Pericardial effusion may be present in approximately 20% of cases. This report presents a patient with a previously diagnosed thymoma without surgical indication and with poor response to chemotherapy and radiotherapy who had a pericardial effusion that likely resulted from the malignancy dissemination to pericardium.
Significado de velho e velhice segundo estudantes de enfermagem: subsídios para a reformula o do ensino de gradua o
Lígia Carvalheiro Fernandes,Yeda Aparecida de Oliveira Duarte
Saúde Coletiva , 2009,
Abstract: Este estudio tuvo como objetivo identificar la contribución del actual curriculum de graduación en enfermería de una universidad pública en la construcción de lo significado de "viejo" en el ámbito académico de enfermería. Se aplica tanto a la escala de diferencial semántico, validado y adaptado por Neri, construido para identificar las actitudes de los adultos jóvenes con los ancianos. Todos los estudiantes regularmente inscritos fueron invitados a participar en el estudio. Se levantó el 70,7% la participación en la investigación y la muestra se corresponde con los jóvenes (edad media 19 a os), y las mujeres solteras, 73,6% reportó vivir juntos antes con ancianos y estas sido clasificadas como positivas. Los resultados obtenidos mediante la aplicación de la escala no mostró diferencias significativas entre el primer y cuarto a o, mostrando poco impacto de la actual plan de estudios para graduarse en la formación de actitudes diferentes en los ancianos. Estos resultados muestran la urgencia de la adecuación del plan de estudios de posgrado de las tendencias identificadas para el siglo XXI, donde la atención gerontológica, por lo tanto, es alto.
Enzimas no testículo de ratos em algumas condi??es experimentais
Póvoa Junior, Helion;Fernandes, Lígia;Marcondes, Neusa;Vicente, Maria Marfisa Aguiar;
Memórias do Instituto Oswaldo Cruz , 1980, DOI: 10.1590/S0074-02761980000100004
Abstract: got, gpt and ceruloplasmin activities have been determined in testicle of normal rats. low activities were found for every enzyme. in animals injected with cadmium chloride, there were significant alterations in enzyme activities. accentuated alterations in enzyme activities were also found in animals with destroyed testicles after injection of several hormones (testosterone, estradiol, progesterone and chorionic gonadotrophin).
Potencial de vida útil pós-colheita de quatro genótipos de mel?o tipo Galia
Morais, Patrícia Lígia Dantas de;Menezes, Josivan Barbosa;Oliveira, Odaci Fernandes de;
Ciência e Agrotecnologia , 2004, DOI: 10.1590/S1413-70542004000600013
Abstract: the postharvest life span of galia (genotypes primal, solarking, total, and vicar) melons (cucumis melo l.) was evaluated by a four (genotypes) x four (storage periods: 0, 3, 6, and 9 days) factorial experiment, in a completely randomized design with three replications. the fruits were harvested at maturation stage iv (yellow color predominance), and stored under 20 ± 1oc and hr 50 ± 2%. solarking's average firmness was better than that of the other genotypes during the experimental period. at the beginning of the experiment all genotypes had soluble solids contents at the level (eight to ten percent) required for exportation, with these levels varying slightly during storage. the internal aspect limited to six days the postharvest life span of genotype total. solarking, vicar, and primal showed great postharvest conservation potential, particularly the genotype solarking, which showed an adequate internal aspect up to the ninth day of storage.
Análise do fenómeno de base segura em contexto familiar: as rela??es crian?a/m?e e crian?a/pai
Monteiro,Lígia; Veríssimo,Manuela; Vaughn,Brian E.; Santos,António J.; Fernandes,Marília;
Psicologia , 2008,
Abstract: this paper high lights the importance of a family system approach to the study of attachment, in a naturalistic environment, by analysing the way the child uses both mother and father as a secure base, as well as, the concurrence or independence of this attachment relationships. 56 mother/child and father/child díades participated in the study. children?s ages range between 29 and 38 months. independent observers, made home observations of the child with the mother and the child with the father, using the aqs (waters, 1995). no differences were found between mean averages for security scores for mothers and fathers, showing that the child is able to use both parents as secure-bases. significant differences were found in the proximity and physical contact scales between both parents, suggesting that mothers and fathers probably have different communicative styles. a significant correlation was found between security scores for mother and father, a result comparable to the one obtained by veríssimo et al. (2006). this could be explained by the similarity on parental caregiving behaviour.
Ovos e órg os reprodutores de fêmeas de Angiostrongylus costaricensis s o reconhecidos mais intensamente por soros humanos de fase aguda na angiostrongilíase abdominal
Bender Ana Lígia,Maurer Rafael Lucyk,Silva Márcia Cristina Fernandes da,Ben Renata
Revista da Sociedade Brasileira de Medicina Tropical , 2003,
Abstract: O Angiostrongylus costaricensis é um nematódeo intra-arterial de roedores. O homem acidentalmente pode se infectar ao ingerir alimentos ou água contaminados. Nosso objetivo foi o de descrever as estruturas do parasita que s o reconhecidas por soros humanos das fases aguda e convalescente da angiostrongilíase abdominal. O método de imunofluorescência indireta foi empregado para estudar a reatividade sobre ovos íntegros e cortes de vermes fêmeas e de larvas de primeiro estágio (L1). L1 também foram estudadas íntegras e depois de tratamento por sonica o. Fluorescência sempre mais intensa com soros de fase aguda foi detectada na superfície dos ovos inteiros e nos fragmentos de L1 e n o estava presente nem nas L1 inteiras, nem em seus cortes. Uma reatividade inespecífica foi detectada na borda cuticular da cavidade geral e sobre os órg os reprodutores. Os dados indicam que estes órg os s o fonte importante de antigenicidade.
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