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Search Results: 1 - 10 of 7282 matches for " Kyung-Hoon Jung "
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Transmission and Suppression of Avian Influenza Virus  [PDF]
Tai-Jin Kim, Kyung-Hoon Jung, Yeong-Sang Kim
Advances in Bioscience and Biotechnology (ABB) , 2018, DOI: 10.4236/abb.2018.912045
Abstract: The growth of AIV is possible with supply of minerals from aeolian desert dust, as cofactors of enzymes, and thus the blockage of the aeolian desert dusts to the poultry farmhouse is important to suppress the enzymatic activity of AIV. South Georgia of Subantarctic Islands may be the source of Continental AIV, so that Continental AIV can become endemic within the local bird population when surrounding environments are close to Subantarctica of South Georgia. There are food webs in sequence of aquatic virus, bacteria, phytoplankton, zooplankton, krill, fish and squid while penguins feed on the fish or squid infected by mutant virus to generate LPAI after an incubation period. When migratory birds move to the Continents, HPAI can spread in the Continents due to low UV-B radiation, enough feed of rice, wheat, corn, wetland, and mineral-enriched desert dust. The clean room is equipped with air washers to remove aeolian dusts and migratory birds feces from working personnel and equipments, heaters to keep the pasteurisation of ultra-high temperature at 135°C for 1 - 2 seconds to inactivate AIV, humidifier to keep wet state above 65% relative humidity for weak virus activity, and the UV-C lamps (254 nm) to finally inactivate AIV. Since AIV doesn’t like the high salinity and high relative humidity, seawater is blanketed as sprayer to maintain high salinity (>20 ppt) and high relative humidity (>65%) from the top to the bottom of the poultry farmhouses for suppression of AIV transmission from infected aeolian dust coming from outside.
Quasi-Feature based Panoramic Video Creation for Multiview Object Tracking System
Changhan Park,Kyung-Hoon Bae
International Journal of Advanced Robotic Systems , 2009,
Abstract: In this paper we present an efficient approach to building a panoramic video from mutiview cameras and to tracking objects. The proposed panoramic video creation module consists of two functions: (i) selecting four quasi-feature points in two adjacent frames acquired by corresponding multiple cameras and (ii) mosaicing the two images. Four pairs of selected quasi-feature points play a role of similarity reference in registering two adjacent frames. The mosaicing step uses the direct linear transformation (DLT) algorithm. The proposed tracking algorithm uses the active contour model (ASM), which is robust against partial occlusion. The proposed tracking module consists of four functions: (i) landmark point assignment, (ii) principal component analysis (PCA), (iii) modeling of local structure, and (iv) model fitting. While most conventional panoramic image creation methods are pixel-based, the proposed feature-based method provides more accurate tracking result. In the experiment, the created panoramic images exhibit high quality, which enables robust, real-time video tracking.
Honeycomb lattice solvable models
Kyung-Hoon Kwon,Doochul Kim
Physics , 1993,
Abstract: We construct solvable models on the honeycomb lattice by combining three faces of the square lattice solvable models into a hexagon face. These models contain two independent, anisotropy controlling, spectral parameters and their transfer matrices with different spectral parameters commute with each other. At the critical point, the finite-size scaling of the transfer matrix spectrum for the honeycomb lattice models is written in terms of the quantities obtained from the finite-size scaling of the square lattice solvable models. We study in detail the phase transition properties of two models based on the interacting hard square model and the magnetic hard square model, respectively. The models, in general, can be extended to the IRF version of the Z-invariant models of Baxter.
Lyapunov Exponent and the Solid-Fluid Phase Transition
Kyung-Hoon Kwon,Byung-Yoon Park
Physics , 1997, DOI: 10.1063/1.474879
Abstract: We study changes in the chaotic properties of a many-body system undergoing a solid-fluid phase transition. To do this, we compute the temperature dependence of the largest Lyapunov exponents $\lambda_{max}$ for both two- and three-dimensional periodic systems of $N$-particles for various densities. The particles interact through a soft-core potential. The two-dimensional system exhibits an apparent second-order phase transition as indicated by a $\lambda$-shaped peak in the specific heat. The first derivative of $\lambda_{max}$ with respect to the temperature shows a peak at the same temperature. The three-dimensional system shows jumps, in both system energy and $\lambda_{max}$, at the same temperature, suggesting a first-order phase transition. Relaxation phenomena in the phase-transition region are analyzed by using the local time averages.
Overexpression of peroxiredoxin I and thioredoxin1 in human breast carcinoma
Mee-Kyung Cha, Kyung-Hoon Suh, Il-Han Kim
Journal of Experimental & Clinical Cancer Research , 2009, DOI: 10.1186/1756-9966-28-93
Abstract: We investigated levels of expression of both Prx I and Trx1 in breast cancer by real-time polymerase chain reaction (RT-PCR) and Western blot.Levels of messenger RNA (mRNA) for both Prx I and Trx1 in normal human breast tissue were very low compared to other major human tissues, whereas their levels in breast cancer exceeded that in other solid cancers (colon, kidney, liver, lung, ovary, prostate, and thyroid). Among members of the Prx family (Prx I-VI) and Trx family (Trx1, Trx2), Prx I and Trx1 were preferentially induced in breast cancer. Moreover, the expression of each was associated with progress of breast cancer and correlated with each other. Western blot analysis of different and paired breast tissues revealed consistent and preferential expression of Prx I and Trx1 protein in breast cancer tissue.Prx I and Trx1 are overexpressed in human breast carcinoma and the expression levels are associated with tumor grade. The striking induction of Prx I and Trx1 in breast cancer may enable their use as breast cancer markers.Organisms living under aerobic conditions are exposed to reactive oxygen species (ROS) such as superoxide anion (O2-), hydrogen peroxide (H2O2), and nitric oxide (NO), which are generated by redox metabolism, mainly in mitochondria. It has been demonstrated in vitro that ROS in small amounts participate in many physiological processes such as signal transduction, cell differentiation, apoptosis, and modulation of transcription factors [1-3]. All organisms, from prokaryotes to primates, are equipped with different defensive systems to combat the toxic processes of ROS. These defensive systems include antioxidant enzymes such as superoxide dismutases, catalases, glutathione peroxidases, and a new type of peroxidase, the rapidly growing family of peroxiredoxins (Prxs) [3,4].The major functions of Prxs comprise cellular protection against oxidative stress, modulation of intracellular signaling through H2O2 as a second messenger molecule, and regulati
Reinterpretation of the protein identification process for proteomics data
Kyung-Hoon Kwon,Sang Kwang Lee,Gun Wook Park,Kun Cho
Interdisciplinary Bio Central , 2009,
Abstract: In the mass spectrometry-based proteomics, biological samples are analyzed to identify proteins by mass spectrometer and database search. Database search is the process to select the best matches to the experimental mass spectra among the amino acid sequence database and we identify the protein as the matched sequence. The match score is defined to find the matches from the database and declare the highest scored hit as the most probable protein. According to the score definition, search result varies. In this study, the difference among search results of different search engines or different databases was investigated, in order to suggest a better way to identify more proteins with higher reliability.
Analytical methods for proteome data obtained from SDS-PAGE multi-dimensional separation and mass spectrometry
Kyung-Hoon Kwon,Jin Young Kim,Gun Wook Park,Jong Shin Yoo
Journal of Analytical Science & Technology , 2010,
Abstract: For proteome analysis, various experimental protocols using mass spectrometry have been developed over thelast decade. The different protocols have differing performances and degrees of accuracy. Furthermore, the “best”protocol for a proteomic analysis of a sample depends on the purpose of the analysis, especially in connection withdisease proteomics, including biomarker discovery and therapeutics analyses of human serum or plasma. Theprotein complexity and the wide dynamic range of blood samples require high-dimensional separation technology.In this article, we review proteome analysis protocols in which both Sodium Dodecyl Sulfate-Polyacryl Amide GelElectrophoresis(SDS-PAGE) and liquid chromatography are used for peptide and protein separations. Multidimensionalseparation technology supplies a high-quality dataset of tandem mass spectra and reveals signals fromlow-abundance proteins, although it can be time-consuming and laborious work. We survey shotgun proteomicsprotocols using SDS-PAGE and liquid chromatography and introduce bioinformatics tools for the analysis ofproteomics data. We also review efforts toward the biological interpretation of the proteome.
Nuclear Akt promotes neurite outgrowth in the early stage of neuritogenesis
Ji Hye Park1,2,3#, Sang Bae Lee1,#, Kyung-Hoon Lee2,3,* & Jee-Yin Ahn1,3,*
BMB Reports , 2012,
Abstract: In addition to its pivotal role in neuronal survival, PI3K/Aktsignaling is integral to neuronal differentiation and neuriteoutgrowth. However, the exact role of Akt in neuronaldifferentiation is still controversial. Here, we found thatnuclear expression of CA-Akt resulted in unusual rapid neuriteoutgrowth and overexpression of KD-Akt caused multipledendrite growth without specific axon elongation. Moreover,microarray data revealed that the expression of FOXQ1expression was about 10-fold higher in cells with nuclear,active Akt than in control cells. Quantitative real-time PCRanalysis showed that mRNA levels were upregulated inNLS-CA-Akt cells as compared to KD or EV cells. Furthermore,our FACS analysis demonstrated that overexpression ofNLS-CA-Akt accumulate cells in the G1 phase within 24 h,fitting with the rapid sprouting of neuritis. Thus, our dataimplied that at least in this early time frame, the overexpressionof nuclear, active Akt forced cells into neurite developmentthrough probably FOXQ1regulation.
Sampling Frequency Offset Estimation Methods for DVB-T/H Systems
Kyung Hoon Won,Jung Su Han,Hyung-Jin Choi
Journal of Networks , 2010, DOI: 10.4304/jnw.5.3.313-320
Abstract: A precise estimation and compensation of SFO (Sampling Frequency Offset) is an important issue in OFDM (Orthogonal Frequency Division Multiplexing) system, because sampling frequency mismatch between the transmitter and the receiver dramatically degrades the system performance due to the loss of orthogonality between the subcarriers. However, the conventional method causes serious performance degradation of SFO estimation in low SNR (Signal to Noise Ratio) or large Doppler frequency environment. Therefore, in this paper, we propose two SFO estimation methods which can achieve stable operation in low SNR and large Doppler frequency environment. The proposals for SFO estimation / compensation are mainly specialized on DVB (Digital Video Broadcasting) system, and we verified that the proposed method has good performance and stable operation through extensive simulation.
Large-Scale Production of Microalgal Lipids Containing High Levels of Docosahexaenoic Acid upon Fermentation of Aurantiochytrium sp. KRS101  [PDF]
Won-Kyung Hong, Anna Yu, Baek-Rock Oh, Jang Min Park, Chul Ho Kim, Jung-Hoon Sohn, Akihiko Kondo, Jeong-Woo Seo
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.49A1001
Abstract:

In this study, large-scale production of microalgal lipid containing high levels of docosahexaenoic acid (DHA) by fermentation of Aurantiochytrium sp. KRS101 was performed. The microalgal strain yielded productivity of docosahex-aenoic acid (DHA) productivity of 1.08 and 1.6 g/L/d by fermentation at 300-L and 5000-L scale stirrer-type bioreactor. The productivity was significantly enhanced upto 5.6 g/L/d by fermentation at 6000-L scale airlift-type bioreactor, probably due to the reduced shearing force. The microalgal lipid could be efficiently recovered by safe extraction methods such as ethanol extraction, hot water extraction or supercritical fluid extraction, promising commercial potential of the microalgal DHA-rich lipid in the food and feed industry.

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