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Search Results: 1 - 10 of 4717 matches for " Kyu Ri Hwang "
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DNA Microarray Analysis of Gene Expression in Eutopic Endometrium from Patients with Endometriosis  [PDF]
Kyu Ri Hwang, Young Min Choi, Jin Ju Kim, Hye Won Jeon, Min A. Hong
Advances in Reproductive Sciences (ARSci) , 2017, DOI: 10.4236/arsci.2017.54009
Abstract: Pathogenesis of the endometriosis is complex and the etiology is still unclear. The objective of this study was to examine that endometrial gene expression in late secretory phase endometrium differs between patients with and without endometriosis. Five patients with proven advanced-stage endometriosis and 5 controls underwent endometrial biopsy in the late secretory phase. Analysis of eutopic endometrial gene expression was performed using Affymetrix gene arrays and differentially expressed genes were assigned to gene ontology groups based on overrepresented analysis using Database for Annotation, Visualization, and Integrated Discovery software. Four hundred sixty two genes were identified as up-regulated such as matrix metalloproteinase 10, cytochrome P450 family 24 subfamily A polypeptide 1, matrix metalloproteinase 3, chemokine (C-C motif) ligand 20, Rho family GTPase 1, interleukin 1-beta, and insulin-like growth factor binding protein 1. Six hundred forty three genes were down-regulated in all endometriotic samples. A lot of genes related with metabolic process, cellular ketone metabolic process and ncRNA metabolic processing were included. Expression patterns of selected five genes were validated by quantitative real time PCR. The results of this analysis support that the eutopic endometrium from patients with advanced-stage endometriosis has distinct gene expression profile from eutopic endometrium of control without endometriosis.
Generation of cluster-type entangled squeezed vacuum states

Wen Jing-Ji,Shao Xiao-Qiang,Jin Xing-Ri,Zhang Shou,Yeon Kyu-Hwang,

中国物理 B , 2008,
Abstract: We present a scheme to prepare cluster-type entangled squeezed vacuum states (CTESVS) by considering the two-photon interaction between a two-level atom and a high-quality cavity, driven by a strong classical field. After the realization of simple atomic measurements, the generation of CTESVS in four separate cavities is accomplished within the cavity decay time. In the case of large atom--cavity detuning, the scheme is immune to the effect of atomic spontaneous emission.
Efficient Scheme for Implementing a Fredkin Gate via Resonant Interaction with Two-Mode Cavity Quantum Electrodynamics
fficient Scheme for Implementing a Fredkin Gate via Resonant Interaction with Two-Mode Cavity Quantum Electrodynamics

SHAO Xiao-Qiang,WEN Jing-Ji,JIN Xing-Ri,ZHU Ai-Dong,ZHANG Shou,YEON Kyu-Hwang,
邵晓强
,文晶姬,金星日,朱爱东,张寿,YEON,Kyu-Hwang

中国物理快报 , 2007,
Abstract: A scheme for implementing a Fredkin gate with an atom sent through a microwave cavity is proposed. The scheme is based on the resonant atom-cavity interaction so that the gating time is sharply short, which is important in view of decoherence.
Gene Expression Pattern in Transmitochondrial Cytoplasmic Hybrid Cells Harboring Type 2 Diabetes-Associated Mitochondrial DNA Haplogroups
Seungwoo Hwang, Soo Heon Kwak, Jong Bhak, Hae Sun Kang, You Ri Lee, Bo Kyung Koo, Kyong Soo Park, Hong Kyu Lee, Young Min Cho
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0022116
Abstract: Decreased mitochondrial function plays a pivotal role in the pathogenesis of type 2 diabetes mellitus (T2DM). Recently, it was reported that mitochondrial DNA (mtDNA) haplogroups confer genetic susceptibility to T2DM in Koreans and Japanese. Particularly, mtDNA haplogroup N9a is associated with a decreased risk of T2DM, whereas haplogroups D5 and F are associated with an increased risk. To examine functional consequences of these haplogroups without being confounded by the heterogeneous nuclear genomic backgrounds of different subjects, we constructed transmitochondrial cytoplasmic hybrid (cybrid) cells harboring each of the three haplogroups (N9a, D5, and F) in a background of a shared nuclear genome. We compared the functional consequences of the three haplogroups using cell-based assays and gene expression microarrays. Cell-based assays did not detect differences in mitochondrial functions among the haplogroups in terms of ATP generation, reactive oxygen species production, mitochondrial membrane potential, and cellular dehydrogenase activity. However, differential expression and clustering analyses of microarray data revealed that the three haplogroups exhibit a distinctive nuclear gene expression pattern that correlates with their susceptibility to T2DM. Pathway analysis of microarray data identified several differentially regulated metabolic pathways. Notably, compared to the T2DM-resistant haplogroup N9a, the T2DM-susceptible haplogroup F showed down-regulation of oxidative phosphorylation and up-regulation of glycolysis. These results suggest that variations in mtDNA can affect the expression of nuclear genes regulating mitochondrial functions or cellular energetics. Given that impaired mitochondrial function caused by T2DM-associated mtDNA haplogroups is compensated by the nuclear genome, we speculate that defective nuclear compensation, under certain circumstances, might lead to the development of T2DM.
Three-party quantum secure direct communication based on Greenberger-Horne-Zeilinger states
Xing-Ri Jin,Xin Ji,Ying-Qiao Zhang,Shou Zhang,Suc-Kyoung Hong,Kyu-Hwang Yeon,Chung-In Um
Physics , 2006, DOI: 10.1016/j.physleta.2006.01.035
Abstract: We present a three-party simultaneous quantum secure direct communication (QSDC) scheme by using Greenberger-Horne-Zeilinger (GHZ) states. This scheme can be directly generalized to $N$-party QSDC by using $n$-particle GHZ states. We show that the many-party simultaneous QSDC scheme is secure not only against the intercept-and-resend attack but also against the disturbance attack.
Successful Conservative Management of Ruptured Ovarian Cysts with Hemoperitoneum in Healthy Women
Jee Hyun Kim, Seung Mi Lee, Ji-Hyun Lee, Yu Ri Jo, Min Hoan Moon, Jonghwan Shin, Byoung Jae Kim, Kyu Ri Hwang, Taek Sang Lee, Kwang Bum Bai, Hye Won Jeon
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0091171
Abstract: Study Objective To determine the success rate of the “intended conservative management strategy” of ruptured ovarian cysts with hemoperitoneum and the risk factors for surgical interventions in healthy women of reproductive age. Methods Patients who visited the emergency department with abdominal pain and were diagnosed with a ruptured ovarian cyst with hemoperitoneum between August 2008 and June 2013 were included in this retrospective study. The diagnosis of the ruptured ovarian cysts and hemoperitoneum was based on the clinical symptoms, physical examination and ultrasound and CT imaging. The rate of surgical interventions and the risk factors for surgical intervention were determined. Results A total of 78 women were diagnosed with a ruptured ovarian cyst with hemoperitoneum. Most patients (80.8%, 63/78) were managed conservatively, and 19.2% of the patients (15/78) required a surgical intervention. In the multiple logistic regression analysis, the diastolic blood pressure (dBP) (odds ratio [OR] of 0.921 with 95% confidence interval [CI] of 0.855–0.993) and the depth of the total pelvic fluid collection in CT (DTFC_CT) (OR 1.599 with 95% CI 1.092–2.343) were the significant determining factors of surgical intervention after adjustment. The rate of surgical intervention was 6.5% vs. 15.8% vs. 77.8% in the patients with neither dBP≤70 mmHg nor DTFC_CT≥5.6 cm, those with only one of those features, and those with both, respectively. Conclusion Most cases of ruptured ovarian cysts with hemoperitoneum can be managed conservatively. A low diastolic blood pressure and a large amount of hemoperitoneum suggest the need for surgical intervention.
Scheme for Implementing an N-Qubit Phase Gate via Selective Atom--Field Interaction with Cavity Quantum Electrodynamics
Scheme for Implementing an N-Qubit Phase Gate via Selective Atom-Field Interaction with Cavity Quantum Electrodynamics

SHAO Xiao-Qiang,JIN Xing-Ri,ZHU Ai-Dong,ZHANG Shou,YEONKyu-Hwang,
邵晓强
,金星日,朱爱东,张寿,YEON,Kyu-Hwang

中国物理快报 , 2008,
Abstract: A scheme for implementing a two-qubit phase gate with atoms sent through a high-Q optical cavity is proposed by choosing nonidentical coupling constants between the atoms and cavity. The atomic spontaneous emission can be suppressed due to the large atom-field detuning. Moreover, the scheme can be generalized to implement an N-qubit phase gate and the gating time does not change with an increase of the number of qubits.
Crystallinity, Microstructure and Mechanical Strength of Yttria-Stabilized Tetragonal Zirconia Ceramics for Optical Ferrule  [PDF]
Sung-Dai Kim, Kyu-Seog Hwang
Materials Sciences and Applications (MSA) , 2011, DOI: 10.4236/msa.2011.21001
Abstract: Yttria-stabilized zirconia ceramics were prepared by using different raw materials in order to compare commercially available optical ferrule. Injection-molded cylindrical green compacts were sintered in air at 1350°C, 1400°C and 1450°C for 2 hrs, followed by furnace cooling. Crystallinity, microstructure and mechanical strength of the sintered body were evaluated by using an X-ray diffraction analyses, a field emission-scanning electron microscope, a universal tester, and a micro-hardness tester, respectively. For practical usage, the sample B sintered at 1350°C was favorable because of high tetragonality and good mechanical strength.
SHOCK-ABSORBING EFFECTS OF VARIOUS PADDING CONDITIONS IN IMPROVING EFFICACY OF WRIST GUARDS
Kyu-Jung Kim,Il-Kyu Hwang
Journal of Sports Science and Medicine , 2004,
Abstract: The use of wrist guards has limited efficacy in preventing wrist injuries during falling in many sports activities. The objectives of this study were to measure the ground reaction force of the hand under simulated impact of the forearm and hand complex with different padding conditions of wrist guards and to analyze their impact force attenuation and maximum energy absorption for improved functional efficiency. A total of 15 subjects, wearing a commercial wrist guard, participated in a cable-released hand impact experiment to test four different conditions on the volar aspect of the hand, which include a wrist guard without a volar splint (bare hand), with a volar splint (normal use), with a volar splint and additional viscoelastic polymeric padding, and a volar splint and additional air cell padding. The ground reaction force and acceleration of the hand were measured using a force platform mounted on an anti-vibration table and a miniature accelerometer, respectively. Additional padding on the bare hand could substantially improve the maximum energy absorption by more than 39%, with no differences with each other. However, only the air cell padding could simultaneously improve the impact force attenuation by 32% compared with the bare hand impact without compromising the maximum energy absorption. It is recommended that common wrist guard design should provide more compliant padding in the volar aspect to improve the impact force attenuation through optimal material selection and design
Prevalence of Metabolic Syndrome Is Higher among Non-Obese PCOS Women with Hyperandrogenism and Menstrual Irregularity in Korea
Min-Ju Kim, Nam-Kyoo Lim, Young-Min Choi, Jin-Ju Kim, Kyu-Ri Hwang, Soo-Jin Chae, Chan-Woo Park, Doo-Seok Choi, Byung-Moon Kang, Byung-Seok Lee, Tak Kim, Hyun-Young Park
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0099252
Abstract: Background Hyperandrogenism (HA) has been linked with several components of metabolic syndrome (MetS). Few studies in Asian women have evaluated the important risk factors for and prevalence of MetS according to PCOS subtype. In this study, we investigated differences in metabolic parameters and the prevalence of MetS in two major phenotypic subgroups of PCOS in Korea. Furthermore, we investigated the relationship between HA-associated parameters and MetS. Materials and Methods This cross-sectional observational study was conducted from May 2010 to December 2011 in Korea. A total of 837 females with PCOS, aged 15–40, were recruited from Departments of Obstetrics and Gynecology at 13 hospitals. Of those, 700 subjects with either polycystic ovaries (PCO)+HA+oligomenorrhea/amenorrhea (O) or PCO+O were eligible for this study. MetS was diagnosed according to the modified National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP) III guidelines and the International Diabetes Federation (IDF) criteria. Results MetS was more prevalent in the PCO+HA+O group (19.7%) than in the PCO+O (11.9%) group. There were statistically significant trends for an increased risk of MetS in the PCO+HA+O group compared to the PCO+O group. After adjustment for age, the odds ratio of MetS was 2.192 in non-obese subjects with PCO+HA+O compared to those with PCO+O, whereas the risk of MetS was not different in obese patients. Multivariate logistic regression analysis showed that high free androgen index and low sex hormone-binding globulin were significantly associated with MetS in non-obese women with PCOS, with odds ratios of 4.234 (95% CI, 1.893–9.474) and 4.612 (95% CI, 1.978–10.750), respectively. However, no associations were detected between MetS and SHBG and FAI in obese PCOS subjects. Conclusions Our results indicate that HA and its associated parameters (FAI and SHBG) are significantly associated with MetS in non-obese PCOS subjects, whereas this association was not observed in obese subjects.
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