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Nutritional Assessment of Leaves of Wild Edible Plant Urtica ardence
Jayanti, Kshitij Agarwal* and Prem Saini
Indian Journal of Pharmaceutical and Biological Research , 2013,
Abstract: Considering the growing need to identify alternative bio-nutritional sources, wild edible leaves consumedin forest zone of Uttarakhand, India were evaluated for their nutritive value in order to prioritize edible wildplant suitable for domestication. The result showed significance of wild plant species as important sourceof nutrient for rural poor people. The nutritional value of leaves of wild plant Urtica ardence wereevaluated in terms of protein, carbohydrate, fat, fiber content, vitamin content, reducing sugars andminerals. Urtica ardence had a significant level of above nutrients and therefore was identified aspromising specie for promotion as backyard planting especially farming systems suffering from crop loss,food shortage and chronic malnutrition.
Research: COMPARATIVE STANDARDIZATION OF POLYHERBAL AYURVEDIC FORMULATION: GLUNORM
Kshitij Agarwal*,Gopal Bisht,Shweta Verma,Prem Saini
Pharmacie Globale : International Journal of Comprehensive Pharmacy , 2012,
Abstract: India is a landmark for traditional system of medicine from past few centuries. Most of the medicines are effective but only one major drawback is lack of standardization. So, there is a need to develop a standardization technique to mingle this system of medicine in the main stream of health science. Central Council for Research in Ayurveda and Siddha (CCRAS) has given preliminary guidelines for standardization these conventional formulations. Standardization of herbal formulation is essential in order to assess the quality of drugs. The present paper reports preparation and standardization of a polyherbal formulation which contains Syzgium cumini (seed), Anthrocefhalus cadamba (leaf), Gymnema stylvestre (whole plant), Foenum graceum (seed), Azadirachata indica (leaves), Momordica charantia (seed) This “GLUNORM” churna formulation is used to treat diabetes mellitus. Here we calculate and discussed about Extractive value, Moisture content, Ash value, Carr’s index etc. These parameters are required for authentication of any herbal drug and its formulation.
PREPARATION AND STANDARDIZATION OF MADURISHT: POLYHERBAL FORMULATION
Rani Shama,Agarwal Kshitij,Nanda Deepak,Saini Prem
International Research Journal of Pharmacy , 2012,
Abstract: Pharmaceutical ayurvedic research is aimed at meeting the medical needs of the population for whom appropriate therapeutic remedies are not available or at those that are available are but not effective for various disorders. While meeting medical needs of a polyherbal formulation set some parameters to ensure that the formulation shows desired pharmacological action against various diseases. The selection of an appropriate drug should take into account apart from medical needs and innovative potential for success. The standardization of crude drug materials includes authentication, organoleptic evaluation, ash values, extractive values, moisture content determination and Carr’s index etc. These parameters are required for authentication of any herbal drug and its formulation.
Chronic obstructive pulmonary disease and peripheral neuropathy
Gupta Prem,Agarwal Dipti
Lung India , 2006,
Abstract: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death world-wide and a further increase in the prevalence as well as mortality of the disease is predicted for coming decades. There is now an increased appreciation for the need to build awareness regarding COPD and to help the thousands of people who suffer from this disease and die prematurely from COPD or its associated complication(s). Peripheral neuropathy in COPD has received scanty attention despite the fact that very often clinicians come across COPD patients having clinical features suggestive of peripheral neuropathy. Electrophysiological tests like nerve conduction studies are required to distinguish between axonal and demyelinating type of disorder that cannot be analyzed by clinical examination alone. However, various studies addressing peripheral neuropathy in COPD carried out so far have included patients with COPD having markedly varying baseline characteristics like severe hypoxemia, elderly patients, those with long duration of illness, etc. that are not uniform across the studies and make it difficult to interpret the results to a consistent conclusion. Almost one-third of COPD patients have clinical evidence of peripheral neuropathy and two-thirds have electrophysiological abnormalities. Some patients with no clinical indication of peripheral neuropathy do have electrophysiological deficit suggestive of peripheral neuropathy. The more frequent presentation consists of a polyneuropathy that is subclinical or with predominantly sensory signs, and the neurophysiological and pathological features of predominantly axonal neuropathy. The presumed etiopathogenic factors are multiple: chronic hypoxia, tobacco smoke, alcoholism, malnutrition and adverse effects of certain drugs.
A comparison of peak expiratory flow measured from forced vital capacity and peak flow meter manoeuvres in healthy volunteers
Agarwal Dipti,Gupta Prem
Annals of Thoracic Medicine , 2007,
Abstract: Background: Spirometry measures the mechanical function of lungs, chest wall and respiratory muscles by assessing the total volume of air exhaled from total lung capacity to residual volume. Spirometry and peak flow measurements have usually been carried out on separate equipments using different expiratory maneuvers. Aims: The present study was carried out to determine whether there is a significant difference between peak expiratory flow (PEF) derived from a short sharp exhalation (PEF maneuver) and that derived from a full forced vital capacity (FVC) maneuver in healthy volunteers. Settings: A medical college and tertiary level hospital. Materials and Methods: The present study was carried out during the period from January 2006 to July 2006. The study included 80 healthy volunteers with no coexisting illnesses, who were in the 15-45 years age group and belonging to either sex. They were asked to perform two sets of PEF and FVC maneuvers using the same turbine spirometer; the order was randomly assigned.th Statistical Analysis: The difference between PEF obtained from a peak flow maneuver (PEFPF) and that obtained from a forced vital capacity maneuver (PEFVC) in healthy volunteers was analyzed separately for males and females, as well as for both groups combined, and statistical significance of its correlations with study data parameters was analyzed.th Results: The difference between PEF obtained from a peak flow maneuver (PEFPF) and that obtained from a forced vital capacity maneuver (PEFVC) was statistically significant ( P < 0.001) in males and in females separately and also for both groups combined. PEFPF (517.25 ± 83.22 liters/min) was significantly greater than PEFVC (511.09 ± 83.54 liters/min), as found on combined group mean analysis. However, the difference was small (6.16 + 7.09 liters/min). Conclusions: FVC maneuver can be used over spirometers to detect the PEF; and on follow-up subsequently, the same maneuver should be used to derive PEF. If we are using a peak flow maneuver subsequently, corrections are required to compensate for the difference due to the different maneuver.
A Security Solution for the Transmission of Confidential Data and Efficient File Authentication Based on DES, AES, DSS and RSA
Rajat Chaudhary,,Prem Singh,,Ambika Agarwal.
International Journal of Innovative Technology and Exploring Engineering , 2012,
Abstract: Data security is an integral part of web basedbusiness applications like insurance, banking etc. Theseapplications require a secure infrastructure to meet the securityrequirements of confidentiality, endpoint authentication, messageintegrity and no repudiation. Document encryption/decryptionand signatures/validation are the data security standards thatdefine XML vocabularies and processing rules to meet thesesecurity requirements.In this paper, we present a how a file securely passes fromsender (server) to the receiver (client) through a central gatewaywith web services applications which mean a secure architecturefor the exchange of confidential documents. Designing a securedelectronic system architecture i.e. connected to the centralgateway through which the whole work is established and takesplace accordingly to pass only the files over the internet and havesecurity features like digital signatures. Various algorithms,implementations and coding have been developed forencryption/decryption, signatures/validations and web services.
Lung abscess due to pulmonary candidiasis
Gupta Prem,Agarwal Dipti,Yadav R
Lung India , 2006,
Abstract: Here we describe a patient who developed lung abscess caused by Candida albicans. There was no evidence of disseminated/ extrapulmonary candidiasis or any immunodeficiency. However, he was taking high doses of inhaled corticosteroid for chronic airflow obstruction. CT guided percutaneous needle aspiration provided the specimen which confirmed the diagnosis of pulmonary candidiasis. His sputum culture was also positive for Candida albicans. The patient achieved favourable out-come with a 4 weeks treatment with fluconazole. The case is presented here due to unique possible association of pulmonary candidiasis with intake of high doses of inhaled corticosteroids.
Herbal Medicine Scenario in India and European Countries
Parul Agarwal,Amreen Fatima,Prem Prakash Singh
Journal of Pharmacognosy and Phytochemistry , 2012,
Abstract: Herbal medicines are the synthesis of therapeutic experiences of generations of practising physicians of indigenous systems of medicine for over hundreds of years while nutraceuticals are nutritionally ormedicinally enhanced foods with health benefits of recent origin and marketed in developed countries. Herbal medicines are also ingreat demand in the developed world for primary health care because of their efficacy, safety and lesser side effects. They also offer therapeutics for age-related disorders like memory loss, osteoporosis, immune disorders, etc. for which no modern medicine is available. WHO too has not systematically evaluated traditional medicines despite the fact that it is used for primary health care by about 80% of the world population. However, in 1991 WHO developed guidelines for the assessment of herbal medicine. Suggestions for herbal medicine standardization are outlined. The scenario and perceptions of herbal medicine are discussed.
A young non-immunocompromised woman with diffuse alveolar opacities
Gupta Prem,Verma Manish,Agarwal Dipti,Kumar Sanjay
Lung India , 2010,
Abstract: Diffuse alveolar opacities (DAO) due to pulmonary tuberculosis are usually described in immunocompromised patients. In adult patients residing in high endemic areas such as India, alveolar opacities are not reported frequently in non-immunocompromised pulmonary tuberculosis patients. We describe a twenty-five-year-old woman who presented with bilateral diffuse alveolar opacities and initial diagnostic work up was directed to non-tuberculosis etiologies. Her sputum was not suggestive of tuberculous or any other infective etiology. However, histopathological examination of specimen from fine needle aspiration cytology through percutaneous route suggested chronic granulomatous disease with detection of mycobacterium. Polymerase chain reaction test in BAL and FNAC specimen confirmed tubercular etiology. Though not frequent, pulmonary tuberculous etiology is worth considering in the differential diagnosis of DAO as not only tuberculosis is fully treatable but also early detection shall help to avoid unnecessary invasive tests and cut down transmission to contacts.
Tuberculosis of spleen presenting with pyrexia of unknown origin in a non-immunocompromised woman
Gupta Prem,Fotedar Sanjay,Agarwal Dipti,Sansanwal Pradeep
Lung India , 2008,
Abstract: Splenic lesions due to tuberculosis are extremely rare in immunocompetent indi-viduals and delays in diagnosis are frequent. Here, we describe a 49-year-woman presenting with pyrexia-of-unknown origin with no evidence of any immunodefi-ciency. Computed tomography of the abdomen showed an enlarged spleen having multiple small focal hypodense lesions; the later were confirmed to be of tubercu-lous etiology on histopathological examination. She had favorable response with anti-tubercular chemotherapy. We report this case of tuberculosis spleen in an im-munocompetent individual for its rarity and to highlight the fact that these patients can be managed by medical treatment effectively.
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