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Search Results: 1 - 10 of 1224 matches for " Koichi Asahi "
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SOX Emissions Reduction Policy and Economic Development: A Case of Yokkaichi  [PDF]
Sachiyo Asahi, Akira Yakita
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.31004
Abstract: We find an inverted U-shape relationship between local income and SOX emissions, i.e., the so-called environmental Kuznets curve, in the Yokkaichi area. It is then shown (1) that the income level at the peak of the curve is fairly low relative to those reported for countries and/or the world in the literature, and (2) SOX that the drastic decline in emissions after the peak of the inverted U-shape was brought about by technical progress in cleaning up the environment but not by the declining output levels, despite increases in output level. It should be noted that the local residents’ campaigns moved and backed up the local governments, in contrast to the SOX reductions in developed economies in 1980 pushed by the international agreements, i.e. Sulphur Protocols. The administrative agencies supported by local residents’ campaigns, rather than decreasing returns in production technology, played a critical role even at such a low income level.
Methylglyoxal (MG) and Cerebro-Renal Interaction: Does Long-Term Orally Administered MG Cause Cognitive Impairment in Normal Sprague-Dawley Rats?
Kimio Watanabe,Kana Okada,Ryoji Fukabori,Yoshimitsu Hayashi,Koichi Asahi,Hiroyuki Terawaki,Kazuto Kobayashi,Tsuyoshi Watanabe,Masaaki Nakayama
Toxins , 2014, DOI: 10.3390/toxins6010254
Abstract: Methylglyoxal (MG), one of the uremic toxins, is a highly reactive alpha-dicarbonyl compound. Recent clinical studies have demonstrated the close associations of cognitive impairment (CI) with plasma MG levels and presence of kidney dysfunction. Therefore, the present study aims to examine whether MG is a direct causative substance for CI development. Eight-week-old male Sprague-Dawley (SD) rats were divided into two groups: control ( n = 9) and MG group ( n = 10; 0.5% MG in drinking water), and fed a normal diet for 12 months. Cognitive function was evaluated by two behavioral tests (object exploration test and radial-arm maze test) in early (4–6 months of age) and late phase (7–12 months of age). Serum MG was significantly elevated in the MG group (495.8 ± 38.1 vs. 244.8 ± 28.2 nM; p < 0.001) at the end of study. The groups did not differ in cognitive function during the course of study. No time-course differences were found in oxidative stress markers between the two groups, while, antioxidants such as glutathione peroxidase and superoxide dismutase activities were significantly increased in the MG group compared to the control. Long-term MG administration to rats with normal kidney function did not cause CI. A counter-balanced activation of the systemic anti-oxidant system may offset the toxicity of MG in this model. Pathogenetic significance of MG for CI requires further investigation.
Graph isomorphism completeness for trapezoid graphs
Asahi Takaoka
Computer Science , 2015,
Abstract: The complexity of the graph isomorphism problem for trapezoid graphs has been open over a decade. This paper shows that the problem is GI-complete. More precisely, we show that the graph isomorphism problem is GI-complete for comparability graphs of partially ordered sets with interval dimension 2 and height 3. In contrast, the problem is known to be solvable in polynomial time for comparability graphs of partially ordered sets with interval dimension at most 2 and height at most 2.
Skin Autofluorescence Is Associated with the Progression of Chronic Kidney Disease: A Prospective Observational Study
Kenichi Tanaka, Masaaki Nakayama, Makoto Kanno, Hiroshi Kimura, Kimio Watanabe, Yoshihiro Tani, Yuki Kusano, Hodaka Suzuki, Yoshimitsu Hayashi, Koichi Asahi, Keiji Sato, Toshio Miyata, Tsuyoshi Watanabe
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0083799
Abstract: Background Advanced glycation end product (AGE) accumulation is thought to be a measure of cumulative metabolic stress that has been reported to independently predict cardiovascular disease in diabetes and renal failure. The aim of this study was to evaluate the association between AGE accumulation, measured as skin autofluorescence, and the progression of renal disease in pre-dialysis patients with chronic kidney disease (CKD). Methods Skin autofluorescence was measured noninvasively with an autofluorescence reader at baseline in 449 pre-dialysis patients with CKD. The primary end point was defined as a doubling of serum creatinine and/or need for dialysis. Results Thirty-three patients were lost to follow-up. Forty six patients reached the primary end point during the follow-up period (Median 39 months). Kaplan-Meier analysis showed a significantly higher risk of development of the primary end points in patients with skin autofluorescence levels above the optimal cut-off level of 2.31 arbitrary units, derived by receiver operator curve analysis. Cox regression analysis revealed that skin autofluorescence was an independent predictor of the primary end point, even after adjustment for age, gender, smoking history, diabetes, estimated glomerular filtration rate and proteinuria (adjusted hazard ratio 2.58, P = 0.004). Conclusions Tissue accumulation of AGEs, measured as skin autofluorescence, is a strong and independent predictor of progression of CKD. Skin autofluorescence may be useful for risk stratification in this group of patients; further studies should clarify whether AGE accumulation could be one of the therapeutic targets to improve the prognosis of CKD.
Human Physical Activity Measurement Method Based on Electrostatic Induction  [PDF]
Koichi Kurita
Journal of Sensor Technology (JST) , 2014, DOI: 10.4236/jst.2014.43013
In this study, an effective noncontact and nonattached technique that is based on electrostatic induction current generated during walking motion is proposed for the detection and assessment of human physical activity. In addition, a theoretical model is proposed for the electrostatic induction current generated owing to variation in the electric potential of the human body. The proposed electrostatic induction current model is compared with the theoretical model, and the proposed model is shown to effectively explain the behavior of the electrostatic induction current waveform. The normal walking motions of daily living are recorded with a portable sensor located in a regular house. The obtained results show that detailed information of physical activity such as a gait cycle can be estimated using our proposed technique. Additionally, the walking signal was measured when the subject walked with the ankle and knee fastened to a splint with bandages to simulate a limp. Therefore, the proposed technique, which is based on the detection of signal generated during walking, can be successfully employed to assess human physical activity.
Attractor-Based Simultaneous Design of the Minimum Set of Control Nodes and Controllers in Boolean Networks  [PDF]
Koichi Kobayashi
Applied Mathematics (AM) , 2016, DOI: 10.4236/am.2016.714131
Abstract: Design of control strategies for gene regulatory networks is a challenging and important topic in systems biology. In this paper, the problem of finding both a minimum set of control nodes (control inputs) and a controller is studied. A control node corresponds to a gene that expression can be controlled. Here, a Boolean network is used as a model of gene regulatory networks, and control specifications on attractors, which represent cell types or states of cells, are imposed. It is important to design a gene regulatory network that has desired attractors and has no undesired attractors. Using a matrix-based representation of BNs, this problem can be rewritten as an integer linear programming problem. Finally, the proposed method is demonstrated by a numerical example on a WNT5A network, which is related to melanoma.
Possible Effect of Pressure Solution on the Movement of a Canister in the Buffer of Geological Disposal System  [PDF]
Koichi Shin
International Journal of Geosciences (IJG) , 2017, DOI: 10.4236/ijg.2017.82006
Abstract: One of the major concepts of the geological disposal of high level radioactive waste is to enclose a metallic container with bentonite buffer which is considered to be impermeable and chemically stable. Since the average density of the container is around 6 to 7 and very heavy compared to bentonite, the scenario of container sinking has been evaluated because excess sinking makes short the pathway of nuclide migration in the bentonite and is detrimental to the safety of the disposal system. Previous considerations on container sinking have been made from the viewpoint of mechanical deformation of the bentonite. In this paper, a chemical deformation process is presented as another mechanism of container sinking, which has not been previously considered for the container sinking in the field of radioactive waste disposal. The chemical deformation mentioned in this paper is the deformation through the process of pressure solution of minerals constituting the buffer, transportation by diffusion and precipitation. That such chemical deformation is a ubiquitous phenomenon occurring in various scales in the crust of the earth will be shown through the review of previous works. Then, some future research topics will be suggested which would be required in order to evaluate the container sinking in the safety case for radioactive waste disposal.
Regeneration Traits of Four Dominant Species in a Cool-Temperate Conifer-Hardwood Mixed Forest, Northern Japan  [PDF]
Koichi Takahashi
American Journal of Plant Sciences (AJPS) , 2017, DOI: 10.4236/ajps.2017.813223
Abstract: Regeneration traits of four dominant species were studied during a decade in a cool-temperate conifer-hardwood mixed forest, northern Japan. Dominant species were three canopy species (Tilia japonica, Acer mono and Abies sachalinensis) and a subcanopy species Prunus ssiori. Regeneration traits differed among the four dominant species. The regeneration of a conifer Abies sachalinensis largely depends on major disturbances because its size structure was a bell-shaped pattern. The growth rate of the sub-canopy species Prunus ssiori increased faster with tree size than the other three species, and therefore, this species can reach reproductive stage faster. Although the number of recruits of Tilia japonica was less than the other three dominant species, about one-fourth of Tilia japonica regenerated by the sprouts. Thus, vegetative reproduction is important for the regeneration of Tilia japonica. On the contrary, many recruits were observed in Acer mono, and its recruits and saplings concentrated in canopy gaps, suggesting that the regeneration of Acer mono restricted to canopy gaps. Thus, clear differences in the regeneration traits were recognized in the four dominant species. This study suggests that the species-specific regeneration traits contribute to the species coexistence of the four dominant species through different regeneration niches.
Analysis Using the Daily-level Purchasing Model Focusing on Product Pages at an E-commerce Site
Shota Sato,Yumi Asahi
International Journal of Electrical and Computer Engineering , 2012, DOI: 10.11591/ijece.v2i6.1816
Abstract: -Recently, the e-commerce sites market in Japan is growing. Many companies in e-commerce sites compete for customers each other. Predicting customer’s purchasing is one of interests of e-commerce managers. In this study, we develop the model which captures customer’s purchasing behavior focusing viewing of product pages. As a result of analysis using the model, we found some customers tend to purchase several days after viewing many product pages. The model of this study will helps e-commerce managers to understand customer’s purchasing behavior.
Topological indices, defects and Majorana fermion in chiral superconductors
Daichi Asahi,Naoto Nagaosa
Physics , 2012, DOI: 10.1103/PhysRevB.86.100504
Abstract: We study theoretically the role of topological invariants to protect the Majorana fermions in a model of two-dimensional chiral superconductors which belong to class D of topological periodic table. A rich phase diagram is revealed. Each phase is characterized by the topological invariants for 2d (Z) and 1d (Z2), which lead to the Majorana fermion at the edge of the dislocation and the core of the vortex. Interference of the Majorana fermions originated from the different topological invariants is studied. The stability of the Majorana fermion with respect to the interlayer coupling, i.e., in 3d, is also examined.
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