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Technological Progress in Radiation Therapy for Brain Tumors  [PDF]
Frederik Jozef Vernimmen, Kathy Rock
Journal of Cancer Therapy (JCT) , 2014, DOI: 10.4236/jct.2014.51005

To achieve a good therapeutic ratio the radiation dose to the tumor should be as high as possible with the lowest possible dose to the surrounding normal tissue. This is especially the case for brain tumors. Technological advancements in diagnostic imaging, dose calculations, and radiation delivery systems, combined with a better understanding of the pathophysiology of brain tumors have led to improvements in the therapeutic results. The widely used technology of delivering 3-D conformal therapy with photon beams (gamma rays) produced by Linear Accelerators has progressed into the use of Intensity modulated radiation therapy (IMRT). Particle beams have been used for several decades for radiotherapy because of their favorable depth dose characteristics. The introduction of clinically dedicated proton beam therapy facilities has improved the access for cancer patients to this treatment. Proton therapy is of particular interest for pediatric malignancies. These technical improvements are further enhanced by the evolution in tumor physiology imaging which allows for improved delineation of the tumor. This in turn opens the potential to adjust the radiation dose to maximize the radiobiological effects. The advances in both imaging and radiation therapy delivery will be discussed.

The management of acute parathyroid crisis secondary to parathyroid carcinoma: a case report
Kathy Rock, Nariman Fattah, Diarmuid O'Malley, Enda McDermott
Journal of Medical Case Reports , 2010, DOI: 10.1186/1752-1947-4-28
Abstract: We report the case of a 60-year-old Caucasian man with hypercalcaemic hyperparathyroid crisis associated with parathyroid carcinoma. He presented with a classic hypercalcaemic syndrome and his serum calcium and parathyroid hormone levels were at 4.65 mmol/L and 1743 ng/L, respectively. He initially presented with a two-week history of weakness and lethargy and a one-week history of vomiting, polyuria and polydipsia. An emergency left thyroid lobectomy and left lower parathyroidectomy were performed. There was a prompt decrease in his parathyroid hormone level immediately after surgery. Histology revealed that our patient had a 4-cm parathyroid carcinoma.In patients with parathyroid carcinoma, the optimal surgical treatment is en bloc resection with ipsilateral thyroid lobectomy and removal of any enlarged or abnormal lymph nodes. Surgery is the only curative treatment. In our patient, prompt surgical intervention proved successful. At six months the patient is well with no evidence of disease recurrence. This case highlights the importance of considering a hyperparathyroid storm in the context of a parathyroid carcinoma. Parathyroid carcinoma is a rare entity and our knowledge is mainly derived from case reports and retrospective studies. This case report increases awareness of this serious and life-threatening complication. This report also illustrates how prompt and appropriate management provides the best outcome for the patient.Hypercalcaemic hyperparathyroid crisis is a rare but life-threatening complication of primary hyperparathyroidism. The symptoms of hypercalcaemia are frequently non-specific and reflect multi-organ involvement. This condition should be suspected in acutely ill patients with profound dehydration, gastrointestinal manifestations, urinary symptoms, altered mental state, or cardiac arrhythmias. Parathyroid carcinoma is a rare malignancy with an incidence of 0.5% to 4% of reported cases of primary hyperparathyroidism [1,2].In patients with par
Toon Van Hal. ‘Moedertalen en taalmoeders’. Het vroegmoderne taalvergelijkende onderzoek in de Lage Landen
Jan Rock
De Zeventiende Eeuw : Cultuur in de Nederlanden in Interdisciplinair Perspectief , 2012,
Measuring the Phases of G_E and G_M of the Nucleon
Stephen Rock
Physics , 2001,
Abstract: The nucleon electromagnetic form factors G_E and G_M are complex quantities in the time-like region. The absolute values can be determined by measuring the angular distribution of the nucleons in e^+ e^- --> N N-bar. The complex phase can only be determined by measuring one or more polarizations of the initial or final state. For PEP-N, we can use unpolarized e+ and e- and measure the polarization of one of the outgoing nucleons.
Obstructive sleep apnea syndrome: The case of residual sleepiness  [PDF]
Kathy Sexton-Radek
Health (Health) , 2013, DOI: 10.4236/health.2013.511252
Abstract: The case of a 62-year-old male illustrated the medical emergent need for treatment. Severe excessive daytime sleepiness, neurocognitive functioning symptoms were evident from his chronic untreated sleepiness. An all-night polysomnogram confirmed the diagnosis of Obstructive Sleep Apnea (OSA). The implication of this case’s chronic untreated experience of OSA is discussed in terms of neurocognitive/brain structure laboratory findings. Results at intake, one and three months of this case’s sleep and cognitive functioning are reported.
Examining Prelingually Deaf and Hard of Hearing College Students on Self Identity and Acculturation  [PDF]
Kathy J. Weldon
Psychology (PSYCH) , 2017, DOI: 10.4236/psych.2017.814155
Abstract: Acculturation as an experience tends to refer to immigrants. The study used this theory to look at how deaf individuals’ become acculturated into either hearing culture or Deaf culture. The Deaf Acculturation Scale (DAS) was used to examine four acculturation styles, including Hearing Acculturated, Bicultural Acculturated, Deaf Acculturated, and Marginal Acculturated. The focus of the project was to investigate the impact of the type of K-12 school experience, either in a mainstream program or a school for the Deaf, had on this acculturation style. Results of the study showed a statistically significant difference in college students’ acculturation scores based on their K-12 school experience. Results are discussed with regards to the impact of early life experiences on later identity and acculturation into the dominant hearing culture or the minority Deaf culture.
Acquisition of Weak Signals in Multi-Constellation Frequency Domain Receivers  [PDF]
Kaveh Mollaiyan, Rock Santerre, René Jr. Landry
Positioning (POS) , 2013, DOI: 10.4236/pos.2013.42014

New positioning applications’ availability requirements demand receivers with higher sensitivities and ability to process multiple GNSS signals. Possible applications include acquiring one signal per GNSS constellation in the same frequency band and combining them for increased sensitivity or predicting acquisition of other signals. Frequency domain processing can be used for this purpose, since it benefits from parallel processing capabilities of Fast Fourier Transform (FFT), which can be efficiently implemented in software receivers. On the other hand, long coherent integration times are mainly limited due to large FFT size in receivers using frequency domain techniques. A new method is proposed to address the problems in frequency domain receivers without compromising the resources and execution time. A pre-correlation accumulation (PCA) is proposed to partition the received samples into one-code-period blocks, and to sum them together. As a result, the noise is averaged out and the correlation results will gain more power, provided that the relative phase between the data segments is compensated for. In addition to simplicity, the proposed PCA method enables the use of one-size FFT for all integration times. A post-correlation peak combination is also proposed to remove the need for double buffering. The proposed methods are implemented in a configurable Simulink model, developed for acquiring recorded GNSS signals. For weak signal scenarios, a Spirent GPS simulator is used as a source. Acquisition results for GPS L1 C/A and GLONASS L1OF are shown and the performance of the proposed technique is discussed. The proposed techniques target GNSS receivers using frequency domain processing aiming at accommodating all the GNSS signals, while minimizing resource usage. They also apply to weak signal acquisition in frequency domain to answer the availability demand of today’s GNSS positioning applications.

Relationships between Structure, Composition, and Dynamics of the Pristine Northern Boreal Forest and Air Temperature, Precipitation, and Soil Texture in Quebec (Canada)
Louis Duchesne,Rock Ouimet
International Journal of Forestry Research , 2009, DOI: 10.1155/2009/398389
Abstract: This study reports on the contemporary structure, composition, and dynamics of the pristine northern boreal forest in Quebec, Canada, associated with air temperature, precipitation, and soil texture, using 147 permanent sample plots located at the limit of continuous forest in Quebec. The results show that tree species composition of stands is associated with stand age, soil texture, air temperature, and precipitation regime. After establishment of the pioneer cohort, the postsuccessional stand dynamics differed among temperature and precipitation regimes, probably because of their influence on tree growth. Our results support the hypothesis that shifts in forest composition related to stand dynamics and the subsequent senescing phase associated with the old growth stage generally occur sooner and proceed faster on more fertile sites due to quicker growth and the subsequent earlier mortality of pioneer species. This study suggests that climate warming should accelerate the successional dynamics of these ecosystems through its positive influence on tree growth.
Harnessing Social Networks along with Consumer-Driven Electronic Communication Technologies to Identify and Engage Members of 'Hard-to-Reach' Populations: A Methodological Case Report
Melanie J Rock
BMC Medical Research Methodology , 2010, DOI: 10.1186/1471-2288-10-8
Abstract: To identify and engage a small yet diverse sample of people who met an unusual set of criteria (i.e., pet owners who had been treating cats or dogs for diabetes), four sampling strategies were used. First, copies of a recruitment letter were posted in pet-friendly places. Second, information about the study was diffused throughout the study period via word of mouth. Third, the lead investigator personally sent the recruitment letter via email to a pet owner, who then circulated the information to others, and so on. Fourth, veterinarians were enlisted to refer people who had diabetic pets. The second, third and fourth strategies rely on social networks and represent forms of chain referral sampling.Chain referral sampling via email proved to be the most efficient and effective, yielding a small yet diverse group of respondents within one month, and at negligible cost.The widespread popularity of electronic communication technologies offers new methodological opportunities for researchers seeking to recruit from hard-to-reach populations.Many populations of interest to health researchers can be hard to reach. These populations may contain few members, be scattered over a large geographic area, be stigmatized, or represent elites with little interest in being studied [1]. The challenges of sampling from hard-to-reach populations are compounded in the absence of accurate or comprehensive information, and whenever few members of a target population regularly interact or even know each other [2]. This paper reports on the sampling strategies deployed for an ethnographic case study that, to explore connections between pet care and human health, focused on pet owner's involvement in treating dogs and cats for diabetes [3,4].A large number of people worldwide are treating dogs and cats for diabetes, yet I faced logistical, ethical, and resource allocation challenges in recruiting even a small number of them. People with diabetic pets constitute a low-frequency population who
Rese a de "Management" de Michael A. Hitt; J. Stewart Black & Lyman W. Porter
Juan Antonio Rock T.
Panorama Socioeconómico , 2006,
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