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Cataract occurrence in patients treated with antipsychotic drugs
Souza, Valéria Barreto Novais e;Moura Filho, Francisco José Rodrigues de;Souza, Fábio Gomes de Matos e;Rocha, Camila Farias;Furtado, Fernando Ant?nio Mendes Lopes;Gon?alves, Tiago Bessa Almeida;Vasconcelos, Karla Feitosa Ximenes;
Revista Brasileira de Psiquiatria , 2008, DOI: 10.1590/S1516-44462008000300008
Abstract: objective: typical antipsychotic drugs, mainly phenothiazines, have been associated with cataract formation for over forty years. recently, there has been a concern about atypical antipsychotic drugs' potential for inducing this lenticular pathology. accordingly, we sought to determine the cataract rate and other ocular side effects in patients on long-term therapy with antipsychotic drugs. method: eighty outpatients with dsm-iv diagnosis of schizophrenia from two settings who met pre determined inclusion criteria were submitted to an ophthalmological evaluation for ocular abnormalities with emphasis in the lens and cornea. they were divided into two groups: group 1 (n = 52) comprised patients who had been predominantly on typical antipsychotics for at least two years and group 2 (n = 28) patients who had been predominantly on atypical antipsychotics for at least two years. results: cataract was found in 26 patients (33%) with predominance of anterior capsular cataract. the cataract rate among patients from group 1 (40%) was higher than among those from group 2 (18%). visual acuity was reduced in 21 patients (26%). no changes were observed neither in the cornea nor in the retina. conclusions: patients using antipsychotic drugs should be submitted to a periodic ophthalmological evaluation.
Intraocular pressure in schizophrenic patients treated with psychiatric medications
Souza, Valéria Barreto Novais e;Moura Filho, Francisco José Rodrigues de;Souza, Fábio Gomes de Matos e;Pereira Filho, Sergio Augusto Carvalho;Coelho, Suele Serra;Furtado, Fernando Ant?nio Mendes Lopes;Gon?alves, Tiago Bessa Almeida;Vasconcelos, Karla Feitosa Ximenes;
Arquivos Brasileiros de Oftalmologia , 2008, DOI: 10.1590/S0004-27492008000500009
Abstract: purpose: in order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications. methods: twenty-eight outpatients with dsm-iv diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with goldmann applanation tonometry. results: raised intraocular pressure was found in three patients (11%). abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. all these four patients were taking only ziprasidone. conclusions: patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.
A constru??o do conhecimento na odontologia: a produ??o científica em debate
Amorim, Karla Patrícia Cardoso;Alves, Maria do Socorro Costa Feitosa;Germano, Raimunda Medeiros;
Acta Cirurgica Brasileira , 2005, DOI: 10.1590/S0102-86502005000700003
Abstract: purpose: analyze, quantitatively, which odontology magazines are being consulted and read by surgeon-dentists, and evaluate the profiles of the mostly cited. methods: 370 polls were made, during the xvii congresso pernambucano de odontologia (pernambucan congress of odontology) and the ix congresso de odontologia do rio grande do norte (congress of odontology of rio grande do norte), which took place, respectively, in april and september 2004. the participants were volunteering professionals divided among general practice (37.84%) and ten differing specialties (62.16%); of which 77,02% had up to ten years of graduation. results: resulting the researches made, 620 quotes were generated, in which, 35 different magazines, national and international, were quoted. by analyzing the data collected, we observe that three magazines summed more than half of the quota (52.74%), which are: revista da associa??o paulista de cirurgi?es dentistas - apcp (magazine of the paulista association of surgeon-dentists), revista da associa??o brasileira de odontologia - abo national (magazine of the brazilian association of odontology) and the revista brasileira de odontologia - rbo (brazilian magazine of odontology). conclusion: despite the participants of the research being, in their majority, specialists, we observe a tendency of a greater consultation of the magazines of general characteristic. these magazines predominantly tackle clinical and technical subjects and present an expressive circulation, great penetration in the odontologic world, easy accessibility and a long time in the market (two of them are over 50 years-old). according to capes - qualis, all possess a b national concept. therefore, it is necessary a deepening of this study, so as to analyze qualitatively what kind of subjects and themes these magazines touch, since they influence the odontologic formation and practice.
Efeito da suplementa??o com vitamina A sobre a concentra??o de retinol no colostro de mulheres atendidas em uma maternidade pública
Ribeiro, Karla Danielly da Silva;Araújo, Katherine Feitosa de;Dimenstein, Roberto;
Revista da Associa??o Médica Brasileira , 2009, DOI: 10.1590/S0104-42302009000400022
Abstract: objective: the aim was to evaluate the effect of supplementary vitamin a upon the colostrum retinol levels in puerperal women cared for at a public maternity hospital in natal, rn, brazil. analysis was conducted on the influence of the colostrum retinol and the maternal nutritional condition as response to supplementation. methods: for analysis of serum retinol 5ml of fasting blood and two samples of milk were collected before and 24 hours after supplementation. a questionnaire was used to define the frequency of previous vitamin a intake. high efficiency liquid chromatography was used to analyze the retinol. results: vitamin a intake was 1492.4 ± 1264 μgrae/day and 23% probably had an inadequate intale. at the beginning of supplementation, 0 hour, and at 24 hours, the control and supplemented groups presented serum retinol concentrations of 1.3 ± 0.4 and 1.4 ± 0.4 μmol/l (7% deficiency) and 3.5 ± 1.7 μmol/l and 3.3 ± 1.8 μmol/l (p>0.05) at 0 hour colostrum, respectively. retinol in the 24 hours milk of the supplemented group increased from of 3.6 ± 1.9 and 6.8 ± 2.6 μmol/l (p<0.0001), respectively. women with deficient levels of retinol in the colostrum at 0 hour(<2.04 mol/l) transferred more retinol to the colostrum at24 hours milk than those with adequate levels (an increase of 326.1% and 86.5%, respectively). conclusion: the megadose of vitamin a was efficient in the first 24 hours after supplementation. the supplementation response was influenced by the basal levels of retinol in the colostrum. parturient women with low initial levels of retinol transferred more retinol to the milk, after the megadose, than nursing women with sufficient levels. this possibly confirms the action of the vitamin a transfer mechanisms proposed by the mammary gland.
Making species distribution models available on the web for reuse in biodiversity experiments: Euterpe edulis species case study
Fook, Karla Donato;Amaral, Silvana;Monteiro, Ant?nio Miguel Vieira;Camara, Gilberto;Ximenes, Arimatéa de Carvalho;Arasato, Luciana Satiko;
Sociedade & Natureza , 2009, DOI: 10.1590/S1982-45132009000100003
Abstract: currently, biodiversity conservation is one of the most urgent and important themes. biodiversity researchers use species distribution models to make inferences about species occurrences and locations. these models are fundamental for fauna and flora preservation, as well as for decision making processes for urban and regional planning and development. species distribution modelling tools use large biodiversity datasets which are globally distributed, can be in different computational platforms, and are hard to access and manipulate. the scientific community needs infrastructures in which biodiversity researchers can collaborate and share knowledge. in this context, we present a computational environment that supports the collaboration in species distribution modelling network on the web. this environment is based on a modelling experiment catalogue and on a set of geoweb services, the web biodiversity collaborative modelling services - wbcms.
A constru??o do saber em Odontologia: a produ??o científica de três periódicos brasileiros de 1990 a 2004
Amorim, Karla Patrícia Cardoso;Alves, Maria do Socorro Costa Feitosa;Germano, Raimunda Medeiros;Costa, Iris do Céu Clara;
Interface - Comunica??o, Saúde, Educa??o , 2007, DOI: 10.1590/S1414-32832007000100003
Abstract: this paper focuses on analyzing the themes dealt with by three brazilian dentistry magazines, during the period from 1990 to 2004. we start from the assumption that these magazines play an important role in professional formation, because they are dynamic means of publishing knowledge and, thus, they are able to influence and guide the thoughts, reflections and attitudes, thereby molding dentistry practice. a quantitative analysis of the empirical material, totaling 2,806 articles, reveals just how diverse the themes and subjects of these publications were. the five most often dealt with themes, relating to technical and professionalizing subjects, represent 52.73% of the works we analyzed. we hope to be able to contribute to a better understanding of the knowledge-building process, leading to reflection and subsequent studies that will also work as a parameter for monitoring thinking in the dental area.
Reincidência de gravidez em adolescentes
Bruno, Zenilda Vieira;Feitosa, Francisco Edson de Lucena;Silveira, Karla Pinheiro;Morais, Ivany Queiroz de;Bezerra, Maria de Fátima;
Revista Brasileira de Ginecologia e Obstetrícia , 2009, DOI: 10.1590/S0100-72032009001000002
Abstract: purpose: to evaluate epidemiological aspects in recurrent adolescence pregnancy. methods: cohort study including 187 pregnant adolescents attended and followed-up for five years after delivery in an adolescent's attendance service in ceará state. age group, being or not at school, living with parents, schooling, marital status and the present partner's condition were analyzed. data were processed by the epi-info program. statistical analysis of the independent variables (age, schooling, being at school, having a job, living with parents, marital status and switching partners) was done and compared to the dependent variable (being or not pregnant after five years). the fisher's exact test was used to evaluate the association among factors which could influence the pregnancy recurrence, the association being present when p<0.05. risks related to schooling, marital status and multiple partners have been calculated, since these were significant factors for pregnancy recurrence. results: 61% of the adolescents got pregnant in the five years after the first delivery. factors such as age, school, work or living with parents were not protective. nevertheless, when the adolescents had eight or less years of schooling, the risk of getting pregnant has almost duplicated (relative risk (rr)=1.8 (ci95%=1.3-2.6)). new pregnancies were more frequent among the single adolescents without a stable partner (rr=1.3 (ci95%=1.1-1.6) and among the ones who had multiple partners (rr=1.4 (ci95%=1.1-1.7)). conclusions: low schooling, multiple partners and non-stable bonds were risk factors for pregnancy recurrence.
Análise espacial dos determinantes socioecon?micos dos homicídios no Estado de Pernambuco
Lima,Maria Luiza C de; Ximenes,Ricardo A de A; Souza,Edinilsa Ramos de; Luna,Carlos Feitosa; Albuquerque,Maria de Fátima P Milit?o de;
Revista de Saúde Pública , 2005, DOI: 10.1590/S0034-89102005000200006
Abstract: objective: to investigate the association between homicide rates and socio-economic variables taking into account the spatial site of the indicators. methods: an ecological study was conducted. the dependent variable was the rate of homicides among the male population aged 15 to 49 years, residing in the districts of the state of pernambuco from 1995 to 1998. the independent variables were an index of the living conditions, per capita family income, theil inequality index, gini index, average income of the head of the family, poverty index, rate of illiteracy, and demographic density. the following techniques were used in the analysis: a spatial autocorrelation test determined by the moran index, multiple linear regression, a spatial regression model (car) and a generalized additive model for the detection of spatial trend (loess). results: the illiteracy and the poverty index explained 24.6% of the total variability of the homicide rates and there was an inverse relationship. moran′s i statistics indicated spatial autocorrelation between municipalities. the multiple linear regression model best fitted for the purposes of this study was the conditional auto regressive (car) model. the latter confirmed the association between the poverty index, illiteracy and homicide rates. conclusions: the inverse association observed between socio-economic indicators and homicides may be expressing a process that propitiates improvement in living conditions and that is linked predominantly to conditions that generate violence, such as drug traffic.
Os fatores associados à tuberculose pulmonar e a baciloscopia: uma contribui??o ao diagnóstico nos servi?os de saúde pública
Ferreira, Aurigena Antunes de Araújo;Queiroz, Karla Cristiana de Souza;Torres, Kerginaldo Paulo;Ferreira, Maria ?ngela Fernandes;Accioly, Horácio;Alves, Maria do Socorro Costa Feitosa;
Revista Brasileira de Epidemiologia , 2005, DOI: 10.1590/S1415-790X2005000200006
Abstract: objectives: this study aims to find the main factors associated with pulmonary tuberculosis and sputum smear. design: a cross-sectional study based on secondary records. sample and methods: the study included one hundred eight-nine (189) patients up to 25 years of age who received care at hospital giselda trigueiro (natal/rn) from 2000 to 2002. associated factors were collected from patient records. results: the results demonstrated that the factors associated to tuberculosis were alcoholism and smoking (20.6%), alcoholism (16.7%), smoking (19.8%), diabetes (8.7%), direct infection (10.3%), untreated pneumonia (6.3%), abandoned treatment (6.3%), and other factors (11.1%). sputum smear was performed in 84.1% of the cases. 44.7% of these presented positive results and 55.3% were negative. conclusion: the factors associated to pulmonary tuberculosis may contribute towards its diagnosis, since the sputum smear presents low sensitivity.
Níveis de alfa-tocoferol no soro e leite materno de puérperas atendidas em maternidade pública de Natal, Rio Grande do Norte
Garcia, Lígia Rejane Siqueira;Ribeiro, Karla Danielly da Silva;Araújo, Katherine Feitosa de;Azevedo, Gabrielle Mahara Martins;Pires, Jeane Franco;Batista, Samara Dantas;Dimenstein, Roberto;
Revista Brasileira de Saúde Materno Infantil , 2009, DOI: 10.1590/S1519-38292009000400006
Abstract: objectives: to evaluate levels of alpha-tocopherol in the serum and breast-milk of women at various stages in lactation and to confirm whether nutritio nally appropriate levels of vitamin e are present in the milk given to the babies. methods: thirty-two child-bearing women with an average age of 25 years took part in the study. 5 ml of blood and 2 ml of colostrum were collected, under fasting conditions, for the purposes of analyzing the levels of alpha-tocopherol. between 10 to 15 days after childbirth, a further 2 ml of breast-milk was collected. the samples were analyzed using high-efficiency liquid chromatography. the nutritional adequacy of the breast-milk in terms of vitamin e content was calculated by multiplying the estimated volume of milk ingested by the infant by the concen tration of α-tocopherol in the breast-milk and comparing this directly with the gold standard for intake of this nutrient (4 mg/day). results: alfa-tocopherol in the blood were 29 ± 0.9 μmol/l (mean ± standard error) and in the colostrum and transition milk were 28.7 ± 4,7 μmol/l and 7.8 ± 1.0 μmol/l, respectively. the estimated consumption of colostrum provided 241% the recommended dietary intake and the transition milk provided 66%. conclusions: the group of women under study had nutritionally adequate levels of vitamin e, and these levels are reflected in their breast-milk, especially in the colostrum, which contained more than double the nutritional requirement of the infant.
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