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Search Results: 1 - 10 of 528802 matches for " Karl-G sta Ljungstr m "
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Percutaneous transluminal angioplasty between 1998 and 2002: Outcomes of interventions proximal and distal to the inguinal ligament
Louise Egberg, Anne-Cathrine Mattiasson, Karl-G sta Ljungstr m, Johan Styrud
Open Access Surgery , 2008, DOI: http://dx.doi.org/10.2147/OAS.S3898
Abstract: cutaneous transluminal angioplasty between 1998 and 2002: Outcomes of interventions proximal and distal to the inguinal ligament Original Research (3960) Total Article Views Authors: Louise Egberg, Anne-Cathrine Mattiasson, Karl-G sta Ljungstr m, Johan Styrud Published Date September 2008 Volume 2008:1 Pages 9 - 19 DOI: http://dx.doi.org/10.2147/OAS.S3898 Louise Egberg1,2, Anne-Cathrine Mattiasson1,2,3, Karl-G sta Ljungstr m1, Johan Styrud1 1Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Surgery, Stockholm, Sweden; 2Sophiahemmet University College, Stockholm, Sweden; 3Department of Nursing, Health and Culture University West, Trollh ttan, Sweden Objective: The aim of this study was to examine patients who have undergone percutaneous transluminal angioplasty (PTA) in order to describe patient characteristics and outcomes of interventions proximal and distal to the inguinal ligament and to assess whether different living situations may be associated with the outcome of PTA-intervention. Design: A retrospective descriptive chart review. Setting: A Swedish University Hospital between January 1998 and December 2002. Participants: All patients who have undergone PTA. Main outcome measure: Medical and nursing records from medical, surgical, orthopedic, and geriatric clinics were reviewed to obtain data. A study-specific protocol was developed. Results: Eighty-seven patients were treated with PTA proximal and 101 distal to the inguinal ligament. No significant differences regarding outcome were found. Fifty-two patients had hematoma/bruise as a complication, which was more common among non-diabetic patients; 46 without diabetes versus 6 diagnosed with diabetes (p = 0.001). When comparing patients living situations and mortality, 76 of the deceased patients had been living alone compared to 38 of the survivors (p = 0.001). Conclusions: The patients were younger in the proximal group, however no differences in outcome were found between patients who had undergone PTA whether proximal or distal to the inguinal ligament. Hematomas/bruises as a complication were more common among nondiabetic patients. Amputation was a strong predictor of death during follow-up.
Percutaneous transluminal angioplasty between 1998 and 2002: Outcomes of interventions proximal and distal to the inguinal ligament
Louise Egberg,Anne-Cathrine Mattiasson,Karl-Gösta Ljungström,Johan Styrud
Open Access Surgery , 2008,
Abstract: Louise Egberg1,2, Anne-Cathrine Mattiasson1,2,3, Karl-G sta Ljungstr m1, Johan Styrud11Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Surgery, Stockholm, Sweden; 2Sophiahemmet University College, Stockholm, Sweden; 3Department of Nursing, Health and Culture University West, Trollh ttan, SwedenObjective: The aim of this study was to examine patients who have undergone percutaneous transluminal angioplasty (PTA) in order to describe patient characteristics and outcomes of interventions proximal and distal to the inguinal ligament and to assess whether different living situations may be associated with the outcome of PTA-intervention.Design: A retrospective descriptive chart review.Setting: A Swedish University Hospital between January 1998 and December 2002.Participants: All patients who have undergone PTA.Main outcome measure: Medical and nursing records from medical, surgical, orthopedic, and geriatric clinics were reviewed to obtain data. A study-specific protocol was developed.Results: Eighty-seven patients were treated with PTA proximal and 101 distal to the inguinal ligament. No significant differences regarding outcome were found. Fifty-two patients had hematoma/bruise as a complication, which was more common among non-diabetic patients; 46 without diabetes versus 6 diagnosed with diabetes (p = 0.001). When comparing patients living situations and mortality, 76 of the deceased patients had been living alone compared to 38 of the survivors (p = 0.001).Conclusions: The patients were younger in the proximal group, however no differences in outcome were found between patients who had undergone PTA whether proximal or distal to the inguinal ligament. Hematomas/bruises as a complication were more common among nondiabetic patients. Amputation was a strong predictor of death during follow-up.Keywords: angioplasty, balloon, peripheral vascular diseases, treatment outcome
Defective Chemokine Production in T-Leukemia Cell Lines and its Possible Functional Role
Jyrki Ivanoff,Anna Ivanoff,Karl-G sta Sundqvist
Clinical and Developmental Immunology , 2000, DOI: 10.1155/2000/28085
Abstract: Peripheral blood lymphocytes and T-cell clones produced nanogram quantities of the chemokines RANTES, MIP-lα, MIP-lβ, MCP-l, IL-8 and GRO-α as well as the motogenic cytokine HGF. In contrast, various T-leukemia cell lines at different stages of differentiation did not produce the same chemokines/cytokines. In order to study the possible functional importance of the poor chemokine production different T-cell lines were compared with respect to development of motile forms and migration on extracellular matrix components in the absence and presence of various chemokines. RANTES, MIP-1α, MIP-1β, IL-8, GRO-α and lymphotactin did not augment the development of motile forms including the size and appearance of the pseudopodia activity of the T-leukemia cell lines. The T-cell lines migrated spontaneously on/to fibronectin in a Boyden chamber assay system. Chemokines augmented the migration of the T-leukemia cell lines on fibronectin in the Boyden system in a chemotactic fashion with peak responses at 10 to 50 ng/ml. Thus, the production of chemokines is defective, in neoplastic T-lymphocytes. The defective chemokine production does not seem to play any major role for the basic locomotor capacity of the cells but may modulate the responsiveness to exogenous chemokines.
Efficacy of injections of phosphatidylcholine into fat deposits-a non-surgical alternative to liposuction in body-contouring
Karl-G Heinrich
Indian Journal of Plastic Surgery , 2005,
Abstract: Injecting phosphatidylcholine has been used in South America as a non-surgical treatment in body contouring. The objective of this study was to demonstrate the efficacy of injecting phosphatidylcholine in the reduction of localised fat deposits. 86 patients were included in the study. Patients received 1-3 treatments in localised fat deposits in various areas of the body using phosphatidylcholine. After treatment with phosphatidylcholine (250 mg / 5 ml), fat deposits show an average circumferential reduction per application of 2.70 cm. No patient showed irregularities, dimples or any serious side effect after treatment. Results remained stable during the time of follow up. All patients showed remarkable reductions of the fat deposits treated with phosphatidylcholine. Using the correct technique, injecting phosphatidylcholine may be a safe and efficacious alternative to liposuction in patients objecting to surgery.
General Resilience to Cope with Extreme Events
Stephen R. Carpenter,Kenneth J. Arrow,Scott Barrett,Reinette Biggs,William A. Brock,Anne-Sophie Crépin,Gustav Engstr?m,Carl Folke,Terry P. Hughes,Nils Kautsky,Chuan-Zhong Li,Geoffrey McCarney,Kyle Meng,Karl-G?ran M?ler,Stephen Polasky,Marten Scheffer,Jason Shogren,Thomas Sterner,Jeffrey R. Vincent,Brian Walker,Anastasios Xepapadeas,Aart de Zeeuw
Sustainability , 2012, DOI: 10.3390/su4123248
Abstract: Resilience to specified kinds of disasters is an active area of research and practice. However, rare or unprecedented disturbances that are unusually intense or extensive require a more broad-spectrum type of resilience. General resilience is the capacity of social-ecological systems to adapt or transform in response to unfamiliar, unexpected and extreme shocks. Conditions that enable general resilience include diversity, modularity, openness, reserves, feedbacks, nestedness, monitoring, leadership, and trust. Processes for building general resilience are an emerging and crucially important area of research.
Fatty acid patterns early after premature birth, simultaneously analysed in mothers' food, breast milk and serum phospholipids of mothers and infants
Karl-G?ran Sabel, Cristina Lundqvist-Persson, Elsa Bona, Max Petzold, Birgitta Strandvik
Lipids in Health and Disease , 2009, DOI: 10.1186/1476-511x-8-20
Abstract: To in a longitudinal study explore the relation between FA status in mothers and infants from an unselected cohort of prematures, not requiring intensive care.Breast milk and mothers' and infants' plasma phospholipid FA concentrations from birth to 44 weeks of gestational age were analysed and compared with mothers' food intake, assessed using a 3-day diary. Fatty acids were analysed by capillary gas-liquid chromatography.The energy intake was low in 75% of mothers, and 90% had low intake of essential FAs (EFAs). Dietary linoleic acid (LA, 18:2w6), but not w3 FAs, correlated to concentrations in breast milk. Infants' plasma and breast milk correlated for arachidonic (AA, 20:4w6), eicosapentaenoic (EPA, 20:5w3) and docosahexaenoic (DHA, 22:6w3) acids. A high concentration of mead acid (20:3w9) in the infants at birth correlated negatively to the concentrations of LA, AA and w3 FAs. Infants of mothers who stopped breastfeeding during the study period showed decreased DHA concentrations and increased w6/w3 ratios, with the opposite FA pattern seen in the mothers' plasma.Although dietary w3 FAs were insufficient in an unselected cohort of mothers of premature infants, breastfeeding resulted in increased levels of DHA in the premature infants at the expense of the mothers, suggesting a general need to increase dietary w3 FAs during pregnancy and lactation.The importance of lipids for growth and development of the central nervous system (CNS) was addressed by Widdowson in 1968 [1], but has been given more attention during the latest decades [2-4]. During the last trimester of pregnancy, a substantial number of essential fatty acids (EFAs), predominantly the long-chain polyunsaturated fatty acids (LCPUFAs) are transferred from the mother to the foetus [5,6]. During this time and in the early neonatal period, rapid synthesis of brain tissue, with cellular differentiation and active synaptogenesis, has a special need for docosahexaenoic (DHA) (22:6w3), eicosapentaenoic (EPA)
Exploring Epistemological Trends in Students’ Understanding of Science from the Perspective of Large-Scale Studies
Anders Jakobsson,Eva Davidsson,Karl-G?ran Karlsson,Magnus Oskarsson
ISRN Education , 2013, DOI: 10.1155/2013/196014
Abstract: This paper highlights how results from large-scale studies can be used to understand students’ knowledge of science. Several scholars express critique of today’s PISA framework, especially with regard to the presentation of the results as national rankings, and suggest alternative and complementary methods. The present study has used PISA data to reveal hidden patterns in the results. The results show a general descending trend in items focusing on the nature of science and how new scientific knowledge is generated. On the other hand, there is an obvious upward trend regarding tasks that measure fact-based elementary or root knowledge. These trends are slightly differentiated at a national level, as the time and magnitude of the decline or increase may vary. 1. Introduction Since the 1990s, the OECD (Organisation for Economic Co-operation and Development) has conducted large-scale PISA studies about students’ knowledge of, and attitudes toward, science, mathematics, and reading. One of the common methods of describing the results from these studies involves comparing the mean values between countries in order to evaluate different educational systems, which also constitutes an important aim of the studies [1–3]. Jakobsson et al. [4] argue that the results of the surveys and tests of educational achievement play an increasingly important role in monitoring educational performance and in political discussions around the world. The test results are used as institutional efficiency indicators, quality assurance measures, and instruments through which politicians, school administrators, and teachers are held accountable [5, 6]. There is an ongoing discussion in the field of science education about the value of these tests, and several scholars express critical opinions about the validity and reliability of the measurements. For example, Sj?berg [7] and Bautier and Rayou [8] argue that the tests do not constitute a valid representation of students performance and knowledge at a national level, and that it is hard to draw any conclusions from the results. They also call attention to the fact that national science curriculum goals in their countries have diverged from the framework of OECD and IEA, and they point out the risk of the tests being considered as “hidden curricula” of science education. Other scholars highlight problems concerning the cultural bias of the tests (e.g., [9]), and the fact that the translating procedure favors English-speaking students [10]. Bottani and Vrignaud [11] also call attention to the inherent conflict between political and
Evaluation of Copper Supplementation to Control Haemonchus contortus Infections of Sheep in Sweden
PJ Waller, G Bernes, L Rudby-Martin, B-L Ljungstrm, A Rydzik
Acta Veterinaria Scandinavica , 2004, DOI: 10.1186/1751-0147-45-149
Abstract: Recently, a large-scale survey was completed that was aimed at determining the prevalence and intensity of nematode infections in organically reared sheep flocks throughout Sweden [12]. This study, conducted over 3 consecutive years, showed that internal nematode parasites were a major disease constraint and Haemonchus contortus was a particular problem. Further epidemiological studies have shown that this parasite has evolved to survive the long, cold winters in Sweden almost entirely within the host as the arrested larval stage, relying almost entirely on the lambing ewe to complete its life cycle [19]. The Swedish Animal Health Service sheep veterinarians (L. Rudby-Martin pers. comm.) and the National Veterinary Institute (D. Christensson pers. comm.) report more clinical cases and more post-mortem causes of death due to H. contortus in recent years, respectively. This may be attributed to several factors that could include the general trend of warmer and wetter grazing seasons, the greater time animals spend on pasture, ineffective de-worming practices, or the further development of anthelmintic resistance in this parasite. Resistance to benzimidazole anthelmintics in H. contortus infections of Swedish sheep flocks was detected more than a decade ago [13], but there have been no further investigations since this time.Certainly the Swedish organic small ruminant (sheep and goat) producers have justifiable causes for concern. This is because the organisations which impose regulations that conform with the statutes developed for organic farming at both the EU level (IFOAM – International Federation of Organic Farming Movements) and nationally (KRAV), stipulate that prophylactic use of any drugs, including anthelmintics, is prohibited. In addition, organically reared animals have to spend more time on pasture, thus potentially exposing them to infective larval pick-up for longer periods. Thus, the problem of H. contortus control will inevitably get worse in organic
Mass and motion of globulettes in the Rosette Nebula
Gsta F. Gahm,Carina M. Persson,Minja M. M?kel?,Lauri K. Haikala
Physics , 2013, DOI: 10.1051/0004-6361/201321547
Abstract: We have investigated tiny molecular clumps in the Rosette Nebula. Radio observations were made of molecular line emission from 16 globulettes identified in a previous optical survey. In addtion, we collected images in the NIR broad-band JHKs and narrow-band Paschen beta and H2. Ten objects, for which we collected information from several transitions in 12CO and 13CO were modelled using a spherically symmetric model. The best fit to observed line ratios and intensities was obtained by assuming a model composed of a cool and dense centre and warm and dense surface layer. The average masses derived range from about 50 to 500 Jupiter masses, which is similar to earlier estimates based on extinction measures. The globulettes selected are dense, with very thin layers of fluorescent H2 emission. The NIR data shows that several globulettes are very opaque and contain dense cores. Because of the high density encountered already at the surface, the rims become thin, as evidenced by our P beta images. We conclude that the entire complex of shells, elephant trunks, and globulettes in the northern part of the nebula is expanding with nearly the same velocity of ~22 km/s, and with a very small spread in velocity among the globulettes. Some globulettes are in the process of detaching from elephant trunks and shells, while other more isolated objects must have detached long ago and are lagging behind in the general expansion of the molecular shell. The suggestion that some globulettes might collapse to form planetary-mass objects or brown dwarfs is strengthened by our finding of dense cores in several objects.
The effect of temperature and water on secondary organic aerosol formation from ozonolysis of limonene, Δ3-carene and α-pinene
. M. Jonsson, M. Hallquist,E. Ljungstr m
Atmospheric Chemistry and Physics (ACP) & Discussions (ACPD) , 2008,
Abstract: The effect of reaction temperature and how water vapour influences the formation of secondary organic aerosol (SOA) in ozonolysis of limonene, Δ3-carene and α-pinene, both regarding number and mass of particles, has been investigated by using a laminar flow reactor (G-FROST). Experiments with cyclohexane and 2-butanol as OH scavengers were compared to experiments without any scavenger. The reactions were conducted in the temperature range between 298 and 243 K, and at relative humidities between <10 and 80%. Results showed that there is still a scavenger effect on number and mass concentrations at low temperatures between experiments with and without an addition of an OH scavenger. This shows that the OH chemistry is influencing the SOA formation also at these temperatures. The overall temperature dependence on SOA formation is not as strong as expected from partitioning theory. In some cases there is even a positive temperature dependence that must be related to changes in the chemical mechanism and/or reduced rates of secondary chemistry at low temperatures. The precursor's α-pinene and Δ3-carene exhibit a similar temperature dependence regarding both number and mass of particles formed, whereas limonene shows a different dependence. The water effect at low temperature could be explained by physical uptake and cluster stabilisation. At higher temperatures, only a physical explanation is not sufficient and the observations are in line with water changing the chemical mechanism or reaction rates. The data presented adds to the understanding of SOA contribution to new particle formation and atmospheric degradation mechanisms.
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