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Cats Infected by Feline Leukemia Virus—Morpho-Quantitative Evaluation of the Thymus  [PDF]
Flávia Azevedo Cavalcanti de Melo, Anna Clara dos Santos, Kaique Nogueira, André Rodrigues da Cunha Barreto-Vianna, Eduardo Maurício Mendes de Lima
Open Journal of Animal Sciences (OJAS) , 2015, DOI: 10.4236/ojas.2015.53032
Abstract: The feline leukemia virus (FeLV) is a complex disease that affects mainly the immune and hematological systems of cats. And because the thymus was closely associated with the immune system, the aim of this study was to quantify the morphological changes in the thymus of naturally infected and uninfected animals. Thymus morphological changes were evaluated by quantifying the following parameters: thymocytes, fat tissue, thymic corpuscles, connective tissue, and type I and III collagen. This study analyzed a total of seven cats, five in the negative group (Fn) and two in the positive (Fp) group. The areas occupied by thymocytes in FeLV negative (Fn) and positive (Fp) animals were, respectively, 55.16% ± 6.15% and 44.81% ± 6.15% (p = 0.39); adipocytes, 42.14% ± 5.97% (Fn) and 53.42% ± 11.3% (Fp) (p = 0.34); blood vessels, 0.85% ± 0.24% (Fn) and 1.75% ± 0.52% (Fp) (p = 0.15). Whereas thymic corpuscles occupied an area of 0.68% ± 0.19% in negative animals (Fn) only. The connective tissue covered area varied between 12.05% ± 0.68% (Fn) and 10.34% ± 0.62% (Fp) (p = 0.009). Collagen type I (p = 0.30) and type III (p = 0.59) were present in, respectively, 1.73% ± 0.3% and 0.44% ± 0.09% in Fn, and 1.44% ± 0.36 and 0.44% ± 0.13% in Fp. The FeLV virus was not able to completely modify the thymus structure of infected animals, considering the areas occupied by thymocytes, adipose tissue, blood vessels and also type I and III collagens. However, the connective tissue underwent a certain degree of remodeling since less connective tissue area was observed in FeLV infected animals. The absence of thymic corpuscles in immunosuppressed animals suggests a possible connection to thymopoiesis.
VEGF System in Dog’s Thymus—Temporal Expression  [PDF]
Fernanda Rodrigues Agreste, Pedro Primo Bombonato, Kaique Nogueira, Anna Clara dos Santos, André Rodrigues da Cunha Barreto-Vianna, Eduardo Maurício Mendes de Lima
Open Journal of Veterinary Medicine (OJVM) , 2015, DOI: 10.4236/ojvm.2015.510028
Abstract: Given the importance of the thymus to the immune system and the limited knowledge about its development and involution processes, this study evaluated the expression of the vascular endo-thelial growth factor, a key angiogenic factor for the formation of vascular tissue bed and modulation of functions related to cell proliferation and migration, hormone synthesis, and immunomodulation. In this study, thymus samples of dog fetuses (30, 40, 50 and 60 days old), and young (180 days old) and adult (365 days old) dogs were submitted to real-time PCR and Western blot. Time-dependent changes were observed for proteins and genes associated with the development of the vascular system, such as VEGF-A, VEGF-C, Flt-1, KDR, FLT-4, and EG-VEGF. This result demonstrates that these system components play different roles during development and involution of the thymus. Possible functions, such as the modulatory effect on vasculogenesis and microenvironment, influence the proliferation and differentiation of thymocytes, T cells maturation, cell-cell interaction and hormone secretion.
Tax Incentives, Competition and Welfare  [PDF]
Claudio Andre Gondim Nogueira
Modern Economy (ME) , 2012, DOI: 10.4236/me.2012.35080
Abstract: The main objective of this paper is to analyze the impacts of the concession of tax incentives as a tool for entry promotion in a developing region. The simple model and the numerical example presented indicate that the adoption of tax incentives can cause very important effects. The productive structure could be heavily changed and production could increase improving conditions to consumers that benefit from the larger output and lower prices. Furthermore, the need for strategic action by the government in order to increase the chance of success of their development strategies is also emphasized, especially if one considers that firms often behave strategically.
Universos coloniais e 'enfermidades dos negros' pelos cirurgi?es régios Dazille e Vieira de Carvalho
Nogueira, André;
História, Ciências, Saúde-Manguinhos , 2012, DOI: 10.1590/S0104-59702012000500010
Abstract: the article analyzes how the diseases that struck captives in colonial areas were named and explained in the treatise observa??es sobre as enfermidades dos negros (1776), written by french surgeon for the troops on santo domingo island, jean-barthélemy dazille. its translation into portuguese by surgeon-major ant?nio josé vieira de carvalho informs us about the circulation of knowledge among these agents who worked overseas. strongly informed by neo-hippocratism and by other lines of enlightened medicine, dazille's treatise and its translation raises considerations about the dangers of the so-called torrid zones, the general living and working conditions of "negroes," and the ways in which these were attenuated.
Lindembergue Cardoso: aspectos de uma obra plural
Nogueira, Ilza;
Per Musi , 2012, DOI: 10.1590/S1517-75992012000100002
Abstract: in the present article, written just after completing brazilian composer lindembergue cardoso's catalogue of musical works, the author intends to present the composer's archive of musical documents, as well as to discuss characteristic aspects of his musical work. the archive consists of 189 complete and 43 unfinished or incomplete documents. considering that the composer's career developed over 25 years (1965-1989), we must admit that the volume of his legacy is expressive. there are 110 works with opus numbers and other pieces without opus number, among which we find arrangements, incidental music, a few transcriptions and orchestrations. regarding characteristic aspects of his work, the most significant ones are: intimacy with brazilian folk and popular music; religiosity; timbral creativity; eclectic aesthetics, resulting from the interaction between tradition and innovative procedures; a heterodox attitude in the use of traditional musical systems; valorization of scenic expression in musical conception; openness towards the interpreter's creativity; commitment to student and amateur ensembles.
Preconceito racial de marca e preconceito racial de origem: sugest?o de um quadro de referência para a interpreta??o do material sobre rela??es raciais no Brasil
Nogueira, Oracy;
Tempo Social , 2007, DOI: 10.1590/S0103-20702007000100015
Abstract: the objective of this text is to construct an interpretative framework capable of being applied as a set of hypotheses to studies of race relations in brazil. it presents twelve propositions that help determine the differentiating features of two types of prejudice and dynamics of racial situations in brazilian society and us society. this aim in mind, it denominates the form in which these features are presented in brazil as "mark prejudice", and the way in which they are constituted in the united states as "origin prejudice".
Dignidade da pessoa humana: conceito fundamental da ciência jurídica
Roberto Nogueira
Lex Humana , 2009,
Abstract: é caro a todo operador do direito, o princípio jurídico posto no artigo 1o, inciso III, da Constitui o Federal, qual, a dignidade da pessoa humana. Este escrito, faz deste conceito previsto no mundo do dever ser, uma ponte necessária e imprescindível para o estudo do ser do direito brasileiro no que pertine ao seu conceito fundamental.
A cultura material no processo educativo: museus, objectos e ofícios tradicionais na reconstru o de identidades e evoca o de memórias
Nogueira, Sandra
PASOS : Revista de Turismo y Patrimonio Cultural , 2003,
Abstract: The present article, talks mainly about the objects and artifacts role at the educational process of the populations, as well as, their responsability in the reconstruction of the cultural identity of the communities. Because the Museum is the best place for conservation, study and perpetuation of the material culture, the article explains how museums, especially the local museums, can make and mantain the link between the institution itself and the Community, mainly the young people. Analized and proved are also some small but, at same time big events, occured in Portugal, where through the artifacts and the Portuguese Trades, I've been showing that adult and young people are sensitive and attracted to this subject
Sobre a televis o - seguido de a influência do jornalismo e os jogos olímpicos
Nogueira Silvia
Mana , 1999,
Os Clássicos na Literatura Infanto-Juvenil Portuguesa
Carlos Nogueira
ECCOM , 2011,
Abstract: This article analyzes how different writers have adapted to children and young people some of the most important works of Portuguese literature, from Gil Vicente to Fernando Pessoa; and reflects on the impact that the reading of these texts might have on young readers.
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