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Search Results: 1 - 10 of 14712 matches for " KX Tang "
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An endophytic Taxol-producing fungus BT2 isolated from Taxus chinensis var. mairei
BH Guo, YC Wang, XW Zhou, K Hu, F Tan, ZQ Miao, KX Tang
African Journal of Biotechnology , 2006,
Abstract: BT2, a newly isolated endophytic fungus from Taxus chinensis var. mairei, was observed to produce Taxol. Besides Taxol, a potent anticancer drug, BT2 could also yield taxane baccatin III, which was an important intermediate for Taxol and semi-synthesis of Taxol in industry. The isolation of such a fungus may provide a promising alterative approach to produce Taxol, and BT2 can serve as a potential material for fungus engineering to improve Taxol production
Neuropsychological profiles of members of organized crime and drug-traffic organizations
Ostrosky F, Borja KC, Romero Rebollar C, Galván KX
Research and Reports in Forensic Medical Science , 2012, DOI: http://dx.doi.org/10.2147/RRFMS.S32352
Abstract: ropsychological profiles of members of organized crime and drug-traffic organizations Review (1024) Total Article Views Authors: Ostrosky F, Borja KC, Romero Rebollar C, Galván KX Published Date October 2012 Volume 2012:2 Pages 19 - 30 DOI: http://dx.doi.org/10.2147/RRFMS.S32352 Received: 25 June 2012 Accepted: 06 September 2012 Published: 17 October 2012 Feggy Ostrosky, Karina Cecilia Borja, César Romero Rebollar, Karla Ximena Díaz Galván Laboratory of Neuropsychology and Psychophysiology, National Autonomous University of Mexico, Mexico City, Mexico Abstract: Members of organized crime and drug traffic organization have developed a hierarchical model of association while participating in the production, distribution, and commercialization of drugs and defense of their territory. The nature of these organizations leads to extremely violent acts, similar to those performed by psychopathic delinquents. Eighty-two incarcerated male offenders – members of these organizations – were assessed and later classified according to the role they played in the organization: kingpins, money launderers, protectors, enforcers, and distributors/producers. These individuals were paired to a control group of 76 nonincarcerated healthy male volunteers from a community sample. We obtained their psychopathic profile and frontal lobe functioning using the Psychopathy Checklist, Revised (PCL-R), PCL-R score, and the Frontal Lobe and Executive Functions Battery. Kingpins and enforcers were considered as psychopaths across the entire range, while the money launderers fit in the description of successful psychopathy, and interesting contrasts were observed within the groups in the PCL-R factors. The orbitofrontal cortex was the functional area affected in the inmate sample, being more detrimentally affected in the most violent samples, thus providing a useful measure of psychopathy and violence of unimpaired criminals. An objective classification of incarcerated criminals will allow us to distinguish between neuronal and cultural psychopaths and sociopaths, which will help us establish adequate readaptation programs. Social issues were also determinants: it was found that in the environment where these criminals grew up, there is a broad acceptance and validation of lifestyles characterized by the accumulation and showing off of material values over intellectual and social values, which in addition to drug consumption trigger the development of aggressive and violent personalities. Readaptation programs must strengthen cognitive abilities, which are normally diminished in these individuals, and encourage a lifestyle with an “integral wealth perspective” that values not only economic but also personal, social, familial, labor, and cultural assets.
Improvement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG–PLA micelle
Shi YN,Huang W,Liang RC,Sun KX
International Journal of Nanomedicine , 2012,
Abstract: Yanan Shi,1,2,* Wan Huang,1,* Rongcai Liang,1–3 Kaoxiang Sun,2,3 Fangxi Zhang,2,3 Wanhui Liu,2,3 Youxin Li1–31College of Life Science, Jilin University, Changchun, China; 2State Key Laboratory of Long-acting and Targeting Drug Delivery System, Luye Pharmaceutical Co, Ltd, Yantai, China; 3School of Pharmacy, Yantai University, Yantai, China*These authors contributed equally to this workAbstract: To improve the pharmacokinetics and stability of recombinant human erythropoietin (rhEPO), rhEPO was successfully formulated into poly(ethylene glycol)–poly(d,l-lactide) (PEG–PLA) di-block copolymeric micelles at diameters ranging from 60 to 200 nm with narrow polydispersity indices (PDIs; PDI < 0.3) and trace amount of protein aggregation. The zeta potential of the spherical micelles was in the range of 3.78 to 4.65 mV and the highest encapsulation efficiency of rhEPO in the PEG–PLA micelles was about 80%. In vitro release profiles indicated that the stability of rhEPO in the micelles was improved significantly and only a trace amount of aggregate was found. Pharmacokinetic studies in rats showed highly enhanced plasma retention time of the rhEPO-loaded PEG-PLA micelles in comparison with the native rhEPO group. Increased hemoglobin concentrations were also found in the rat study. Native polyacrylamide gel electrophoresis results demonstrated that rhEPO was successfully encapsulated into the micelles, which was stable in phosphate buffered saline with different pHs and concentrations of NaCl. Therefore, PEG–PLA micelles can be a potential protein drug delivery system.Keywords: rhEPO, PEG–PLA micelle, in vitro, pharmacokinetics, pharmacodynamics
Improvement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG–PLA micelle
Shi YN, Huang W, Liang RC, Sun KX, Zhang FX, Liu WH, Li YX
International Journal of Nanomedicine , 2013, DOI: http://dx.doi.org/10.2147/IJN.S38648
Abstract: ovement of in vivo efficacy of recombinant human erythropoietin by encapsulation in PEG–PLA micelle Original Research (1098) Total Article Views Authors: Shi YN, Huang W, Liang RC, Sun KX, Zhang FX, Liu WH, Li YX Published Date December 2012 Volume 2013:8 Pages 1 - 11 DOI: http://dx.doi.org/10.2147/IJN.S38648 Received: 29 September 2012 Accepted: 13 November 2012 Published: 27 December 2012 Yanan Shi,1,2,* Wan Huang,1,* Rongcai Liang,1–3 Kaoxiang Sun,2,3 Fangxi Zhang,2,3 Wanhui Liu,2,3 Youxin Li1–3 1College of Life Science, Jilin University, Changchun, China; 2State Key Laboratory of Long-acting and Targeting Drug Delivery System, Luye Pharmaceutical Co, Ltd, Yantai, China; 3School of Pharmacy, Yantai University, Yantai, China *These authors contributed equally to this work Abstract: To improve the pharmacokinetics and stability of recombinant human erythropoietin (rhEPO), rhEPO was successfully formulated into poly(ethylene glycol)–poly(d,l-lactide) (PEG–PLA) di-block copolymeric micelles at diameters ranging from 60 to 200 nm with narrow polydispersity indices (PDIs; PDI < 0.3) and trace amount of protein aggregation. The zeta potential of the spherical micelles was in the range of 3.78 to 4.65 mV and the highest encapsulation efficiency of rhEPO in the PEG–PLA micelles was about 80%. In vitro release profiles indicated that the stability of rhEPO in the micelles was improved significantly and only a trace amount of aggregate was found. Pharmacokinetic studies in rats showed highly enhanced plasma retention time of the rhEPO-loaded PEG-PLA micelles in comparison with the native rhEPO group. Increased hemoglobin concentrations were also found in the rat study. Native polyacrylamide gel electrophoresis results demonstrated that rhEPO was successfully encapsulated into the micelles, which was stable in phosphate buffered saline with different pHs and concentrations of NaCl. Therefore, PEG–PLA micelles can be a potential protein drug delivery system.
Gateways Placement in Backbone Wireless Mesh Networks  [PDF]
Maolin TANG
Int'l J. of Communications, Network and System Sciences (IJCNS) , 2009, DOI: 10.4236/ijcns.2009.21005
Abstract: This paper presents a novel algorithm for the gate瑆ay placement problem in Backbone Wireless Mesh Networks (BWMNs). Different from existing algorithms, the new algorithm incrementally identi&#64257;es gateways and assigns mesh routers to identi&#64257;ed gateways. The new algorithm can guarantee to &#64257;nd a feasible gateway placement satisfying Quality-of-Service (QoS) constraints, including delay constraint, relay load constraint and gateway capacity constraint. Experimental results show that its performance is as good as that of the best of existing algorithms for the gateway placement problem. But, the new algorithm can be used for BWMNs that do not form one connected component, and it is easy to implement and use.
QoS-Aware Reference Station Placement for Regional Network RTK  [PDF]
Maolin Tang
Journal of Software Engineering and Applications (JSEA) , 2009, DOI: 10.4236/jsea.2009.21007
Abstract: Network RTK (Real-Time Kinematic) is a technology that is based on GPS (Global Positioning System) or more gener-ally on GNSS (Global Navigation Satellite System) measurements to achieve centimeter-level accuracy positioning in real-time. Reference station placement is an important problem in the design and deployment of network RTK systems as it directly affects the quality of the positioning service and the cost of the network RTK systems. This paper identifies a new reference station placement for network RTK, namely QoS-aware regional network RTK reference station placement problem, and proposes an algorithm for the new reference station placement problem. The algorithm can always produce a reference station placement solution that completely covers the region of network RTK.
Sharing and Implementation of Heterogeneous Database for Education Resource Based on XML  [PDF]
Shixi TANG
Journal of Software Engineering and Applications (JSEA) , 2009, DOI: 10.4236/jsea.2009.23027
Abstract: The problem of sharing heterogeneous database for accessing different educational resources has to be considered. The study is carried out to realize the heterogeneous database sharing for educational resources using multi-media educa-tional resources as the researching object. XML is applied as middleware for the practical requirements of education. The study has important practical significance for the intellectualization of educational and teaching resource platform.
Traffic Modeling of a Finite-Source Power Line Communication Network  [PDF]
Shensheng Tang
Smart Grid and Renewable Energy (SGRE) , 2011, DOI: 10.4236/sgre.2011.23029
Abstract: Power line communication (PLC) is a promising smart grid application for information transmission using existing power lines. We analytically model a finite-source PLC network subject to channel failure through a queueing theoretic framework. The proposed PLC network model consists of a base station (BS), which is located at a transformer station and connected to the backbone communication networks, and a number of subscriber stations that are interconnected with each other and with the BS via the power line transmission medium. An orthogonal frequency division multiplexing based technique is assumed for forming the transmission channels in a frequency spectrum. The channels are subject to failure during service due to noise. We determine the steady-state solution of the proposed model and derive a set of performance metrics of interest. Numerical and simulation results are presented to provide further insights into the analytical results. The proposed modeling method is expected to be used for evaluation and design of future PLC networks.
China’s Sui Generis plus Oxymoron- its justification  [PDF]
Shaocheng Tang
Open Journal of Political Science (OJPS) , 2011, DOI: 10.4236/ojps.2011.11001
Abstract: In recent years, China’s overall performance stood out extraordinarily. Although the PRC is not only a socialist but also a developing country, it still has offered financial relief to European countries. None of Beijing’s leaders has been directly elected by the people, but most of them have been proven to be competent. Does this mean that the “Beijing Consensus” has taken over “Washington Consensus”? Given China’s vast population and its unique geographical environment and historical development, compared to European countries, China is sui generis. In the traditional Confucianism, benevolence (仁) is a virtue which human beings are born with, while the Western world is rooted deeply in the Christian culture of “original sin”. As a result the rule of virtue in China contrasts the rule of law in the West, harmony vs. contradiction. China’s “socialist market economy” and “Three Represents” are typical oxymorons but with great success. Since the implementation of a “socialist market economy” in 1992 there has been much more market economy than socialism. Currently, political, social and cultural sectors are lagging behind. Therefore, the gap between the rich and the poor must be reduced efficiently. Nonetheless, the corruption problem remains as another serious and important issue for the CCP. Without independent anti-corruption authorities, it would be extremely difficult for them to tackle this problem. For the time being the Mainland has to count on the leadership to set examples for others.
Knowledge Transferring Features in Traditional Construction Project Team in China: Based on SNA  [PDF]
Yong Tang
Technology and Investment (TI) , 2012, DOI: 10.4236/ti.2012.34032
Abstract: For the uniqueness and one-time feature, construction project is urgently needed in knowledge transferring to acquire its high performance. This paper focuses in the exploration of knowledge transferring features from the network perspective. Based on the data from a real construction project team of 40 members, we find that all members have knowledge transferring behavior, while the knowledge transferring density is comparatively low and distance is long; from cluster analysis we find that 89 different clusters in the whole network, and some members (especially the managers) repeated appear in different clusters and assume the responsibilities in coordinating knowledge transferring.
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