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Search Results: 1 - 10 of 267581 matches for " K. F. Chah "
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Recurring colisepticaemia in batches of birds in a poultry farm in Nsukka, Southeast Nigeria
K. F. Chah, E. C. Okwor
Nigerian Veterinary Journal , 2003,
Abstract: Repeated outbreaks of Escherichia coli infection in pullets and laying birds in a poultry farm in Nsukka, southeast Nigeria are reported. The outbreaks were recorded in four batches of birds; the initial cases occurring in birds 12 – 16 weeks of age while subsequent outbreaks were in birds 28–31 weeks of age. The disease was characterized by depression, inappettence, mild cough and whitish diarrhoea; morbidity was 10% while mortality was about 5%. There was a 15% drop in egg production in laying birds. Post-mortem lesions included peritonitis, pericarditis, hydropericardium and perihepatitis. Pure cultures of E. coli were obtained from the organs cultured. The E. coli strains were sensitive to neomycin, streptomycin, gentamicin, ciprofloxacin, pefloxacin, ofloxacin and chloramphenicol but resistant to tetracycline, nalidixic acid, ampicillin and cotrimoxazole. Biosecurity measures are recommended for the control of avian colisepticaemia in Nigeria. Key Words: Outbreaks, Escherichia coli, pullets, laying birds. (Nigerian Veterinary Journal: 2003 24(1): 48-52)
Bioassay Procedure for the Diagnosis of Aflatoxicosis in a Pig Farm in Nsukka, South East Nigeria  [PDF]
S. V. O. Shoyinka, K. F. Chah, C. P. Eze, W. S. Ezema, I. R. Onoja, P. U. Umeakuana
Open Journal of Veterinary Medicine (OJVM) , 2014, DOI: 10.4236/ojvm.2014.47015
Abstract:

The owner of an intensively reared pig farm in Nsukka, South-East Nigeria reported the deaths (within one week) of 90 piglets (2-3 months of age) out of 150 piglets on the farm. The piglets were being fed home-compounded ration composed of spent grain (which appeared moldy) and other locally sourced materials. Clinical signs observed in affected piglets include sudden loss of appetite, diarrhea and distress grunting sound prior to death. Symptomatic treatment of the piglets which included the use of antibiotics (tetracycline, LA) did not appear to have ameliorated the condition. At necropsy carcasses were generally in fair to good body condition; with subcutaneous hemorrhages, mainly under the skin of head and neck regions. Lungs were congested and edematous, with froth along the tracheal and bronchial airways. The liver and spleen were moderately congested, while the mucosae of the gastrointestinal tract (which was free of ingesta) appeared mildly hyperaemic. No pathogenic bacterium was isolated from the heart blood and spleen. Histologic section of the liver showed centrilobular hepatocytes vacoulation and necrosis with hypertrophy of Kupffer cells that were in erythrophagocytosis. There was moderate fibrinous exudation into the interlobular septae. Spleen section showed severe erythrophagocytosis, but mild haemosiderosis. White pulp was either reactive or depopulated. Lungs were severely haemorrhagic with bronchitis and bronchiolitis. A tentative diagnosis of mycotoxicosis was made and the spent grain-compounded ration was fed to different groups of ducklings, with/without arginine and lysine supplementation. On the bases of clinical signs and mortality pattern; gross and histologic changes in the liver of the ducklings, a definitive diagnosis of aflatoxicosis was made. This paper emphasizes the experimental feeding of suspected feeds/feed ingredient to ducklings as a reliable diagnostic model for aflatoxicosis.

Extended-spectrum beta-lactamase production among ampicillin-resistant Escherichia coli strains from chicken in Enugu State, Nigeria
Chah, K.F.;Oboegbulem, S.I.;
Brazilian Journal of Microbiology , 2007, DOI: 10.1590/S1517-83822007000400018
Abstract: one hundred and seventy-two ampicillin-resistant e. coli strains isolated from commercial chickens in enugu state, nigeria, were screened for beta-lactamase production using the broth method with nitrocefin? as the chromogenic cephalosporin to detect enzyme production. beta-lactamase producing strains were further examined for extended-spectrum beta-lactamase (esbl) production using the oxoid combination discs method. one hundred and seventy (98.8%) of the 172 ampicillin-resistant e. coli strains produced beta-lactamase enzyme. sixteen (9.4%) beta-lactamase producers were phenotypically confirmed to produce esbls. six of the esbl producing strains were only detected with ceftazidime versus ceftazidime/clavulanate combination while ten of the esbl producers were detected with cefotaxime versus cefotaxime/clavulanate combination. chicken may serve as a reservoir of esbl-producing e. coli strains which could be transferred to man and other animals.
Frequency and antimicrobial resistance of aerobic bacteria isolated from surgical sites in humans and animals in Nsukka, Southeast Nigeria
K. F. Chah, C. A. Eze, B. N Oluoha
Nigerian Veterinary Journal , 2003,
Abstract: This study was carried out to evaluate the frequency of occurrence and antimicrobial resistance of aerobic bacteria isolated from surgical sites in human and animal patients in Nsukka, southeast Nigeria. Wound swabs from 132 patients (96 humans and 36 animals) were cultured for bacterial isolation. Antimicrobial resistance profile of the isolates was evaluated by the agar disc diffusion method. A total of 134 bacterial isolates were obtained from 114 samples that yielded growth. Staphylococcus aureus (26.1%) was the most prevalent agent isolated from humans, followed by E. coli (17.4%), Proteus spp (17.4%), Enterococcus spp (13.0%) and coagulase negative Staphylococcus [CNS] (10.9%). In animals, the most common agents isolated were E. coli (19.0%) and Proteus spp (19.0%), followed by S. aureus (14.3%), Enterococcus spp (14.3%) and CNS (9.5%). A high proportion of Gram-negative isolates were resistant to cephalexin (80%), cotrimoxazole (80%), ampicillin (73.3%), gentamicin (70%) and nalidixic acid (70%) while majority of the Gram-positive bacteria were resistant to streptomycin (40.5%) and erythromycin (40.5%). Isolates demonstrated low resistance rate to ciprofloxacin. This study has provided information that may be needed in designing empirical treatment regimens for post-operative infections in Nsukka area. Key Words: Bacteria, isolation, surgical site, antimicrobial, resistance. (Nigerian Veterinary Journal: 2003 24(1): 1-9)
Synthesis, spectroscopic characterization and antibacterial screening of novel n-(benzothiazol-2-yl)ethanamides
Obasi, L.N.;Ukoha, P.O.;Chah, K.F.;Anaga, A.O.;
Eclética Química , 2011, DOI: 10.1590/S0100-46702011000100001
Abstract: synthesis, electronic, infrared, elemental micro analytical studies were carried on n-(benzothiazol-2-yl)trichloroethanamide [4] and n-(benzothiazol-2-yl)chloroethanamide [5]. they were also screened in vitro and in vivo for antibacterial activity. the results indicate that the compounds are very stable and that they show high antibacterial activities against both gram-positive and gram-negative bacteria tested. both derivatives of 2-aminobenzothiazole were active against the multiresistant bacteria with izd ranging from 9 -18 mm [5] and 9 - 20mm [4]. from the mic results it is observed that the [5] derivative produced a better antibacterial activity than the [4] derivative. the lethal concentrations (lc50) of the compounds were also determined. their solubilities and melting points were also determined.
Prevalence of Newcastle Disease Viruses in Wild and Captive Birds in Central Nigeria
O.J. Ibu,J.O.A. Okoye,E.P. Adulugba,K.F. Chah
International Journal of Poultry Science , 2009,
Abstract: Newcastle disease (ND) is an acute rapidly spreading, contagious, nervous and respiratory disease of domestic and wild birds caused by the Avian Paramxyovirus 1, the Newcastle disease (ND) virus. ND is endemic in Nigeria. The reservoir status of wild and captive birds for ND virus in central Nigeria is assessed in this study. Cloacal swabs were taken from one hundred and sixty three birds caught from five Local Government Council areas of Plateau, Benue and Kaduna States in central Nigeria. A total of thirteen ND Viruses were isolated from the three States. Viz: 8 isolates from Plateau, 4 from Benue and 1 from Kaduna State. One hundred and fifty three of the birds sampled belonged to 30 avian species in 10 Orders while ten birds were unidentified. Only 7% of the species in three Orders yielded ND viruses. The 13 isolates were characterized using the Mean death time of the Minimum lethal dose (MTD/MLD); Intracerebral Pathogenicity index (ICPI) Intravenous Pathogenicity index (IVPI) and the Reverse transcriptase polymerase chain reaction (RT/PCR). The results show that 12 of the isolates were of the lento genic strain while 1 isolate belonged to the Merogenic strain. The implication of these findings on the poultry industry in the country is discussed.
Synthesis, Spectroscopic Characterization and Preliminary Antimicrobial Studies of Mn(II) and Cu(II) Complexes of two Thiolates; S,S’-(2,6-Diaminopyridine-3,5-diyl) Dibenzenecarbothioate (DBCT) and S-Benzyl Benzenecarbothioate (BBCT)
P. O. Ukoha,C.U. Alioke,N.L> Obasi,K.F. Chah
Journal of Chemistry , 2011, DOI: 10.1155/2011/214870
Abstract:
Mucormicosis cutánea primaria: a propósito de dos casos. Revisión de la literatura
Tapia E,Oscar; Chahín A,Carolina; Concha F,Carla;
Revista chilena de infectología , 2011, DOI: 10.4067/S0716-10182011000300012
Abstract: mucormycosis or zygomycosis is a rare opportunistic infection caused by aerobic saprophytic fungus that belongs to the class of zygomycetes mucorales family. these organisms live in the environment and enter the body by air, gastrointestinal or skin routes, through solutions of continuity of the skin. this microorganism is generally not pathogenic for immunocompetent hosts, being the development of the disease linked with the immune status of the subject. its mortality is around 50-60%; sometimes in spite of early diagnosis and treatment initiation it has a fatal course. six clinical forms of mucormycosis are described: rhinocerebral, cutaneous, pulmonary, disseminated, gastrointestinal and miscellaneous form. two cases of patients with primary cutaneous mucormycosis diagnosed in the pathology unit of hernan henriquez aravena hospital of temuco, chile are presented here.
Mucormicosis cutánea primaria: a propósito de dos casos. Revisión de la literatura Primary cutaneous mucormycosis: two case reports and literature
Oscar Tapia E,Carolina Chahín A,Carla Concha F
Revista chilena de infectología , 2011,
Abstract: La mucormicosis o zigomicosis es una infección oportunista poco frecuente, causada por un hongo sapró-fito aeróbico que pertenece a la clase Zygomycetes de la familia Mucorales. Estos microorganismos viven en el ambiente y penetran en el organismo por vía aérea, gastrointestinal o cutánea a través de soluciones de continuidad de la piel. Este agente generalmente no es patógeno para el hospedero inmunocompetente estando relacionado el desarrollo de la enfermedad con el estado inmune del sujeto. Su mortalidad es cercana a 50-60%; en ocasiones, a pesar del precoz diagnóstico e instauración del tratamiento, tiene un curso fatal. Se describen seis formas clínicas de mucormicosis: rinocerebral, cutánea, pulmonar, diseminada, gastrointestinal y una forma miscelánea. Se presentan dos casos de pacientes con mu-cormicosis cutánea primaria diagnosticados en la Unidad de Anatomía Patológica del Hospital Hernán Henríquez Aravena de Temuco. Mucormycosis or zygomycosis is a rare opportunistic infection caused by aerobic saprophytic fungus that belongs to the class of Zygomycetes Mucorales family. These organisms live in the environment and enter the body by air, gastrointestinal or skin routes, through solutions of continuity of the skin. This microorganism is generally not pathogenic for immunocompetent hosts, being the development of the disease linked with the immune status of the subject. Its mortality is around 50-60%; sometimes in spite of early diagnosis and treatment initiation it has a fatal course. Six clinical forms of mucormycosis are described: rhinocerebral, cutaneous, pulmonary, disseminated, gastrointestinal and miscellaneous form. Two cases of patients with primary cutaneous mucormycosis diagnosed in the Pathology Unit of Hernan Henriquez Aravena Hospital of Temuco, Chile are presented here.
Effect of ethylene diamine tetraacetic acid (EDTA) on in vitro antibacterial activity of tetracycline and ampicillin against escherichia coli strains
KF Chah, SI Oboegbulem
Nigerian Veterinary Journal , 2005,
Abstract:
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