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Search Results: 1 - 10 of 138559 matches for " K Huruy "
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The effects of Moringa stenopetala on blood parameters and histopathology of liver and kidney in mice
D Ghebreselassie, Y Mekonnen, G Gebru, W Ergete, K Huruy
Ethiopian Journal of Health Development , 2011,
Abstract: Background: Moringa stenopetala and related species are commonly used in folk medicine for various human diseases such as antimalarial, antihypertensive, antidiabetic and as antispasmodic. Objective: The aim of the study is to evaluate the effects of aqueous extract of M. stenopetala on blood parameters, and histopathology of liver and kidney in experimental mice. Methods: Fresh leaves of M. stenopetala were collected from Arbaminch area, Southwest Ethiopia, in November 2005. The leaves were dried and extracted with water. Three month-old Swiss albino male mice, which were kept under uniform laboratory conditions, were randomly divided into four groups (one group of controls and three experimental). (The control group was orally given 0.5 ml of distilled water, and groups II, III and IV were given the aqueous leaf extract of M. stenopetala using intragastric tube to achieve the required doses of 600, 750 and 900 mg/kg body weight, respectively once a day at 24 hours intervals for six weeks and then sacrificed). Blood sample was collected from each mouse and examined for hematological and biochemical parameters. Liver and kidney were removed, stained and examined for histopathological profiles. The effects of treatment with aqueous extract of M. stenopetala on hematological, biochemical and histopathology features were compared with control group following standard procedures. Results: Mice treated with 900 mg/kg of the extract per kg of body weight showed a significant increase in body weight compared to the controls (P=0.014). Neither a significant change in the weight nor in histopathology of liver and kidney were observed in the animals treated with aqueous extract of M. stenopetala compared to those of the controls. Serum glucose level (P=0.034) and serum cholesterol level (P=0.016) decreased significantly after six weeks treatment. Conclusion: The aqueous leaf extract of M. stenopetala is shown to increase body weight and reduce serum glucose and cholesterol level in mice. This indicates nutritional and medicinal values, but we cannot yet recommend its therapeutic use before more and complete studies are done.
Brief Communication: Comparison of formol-acetone concentration method with that of the direct iodine preparation and formol-ether concentration methods for examination of stool parasites
F Moges, Y Belyhun, M Tiruneh, Y Kebede, A Mulu, A Kassu, K Huruy
Ethiopian Journal of Health Development , 2010,
Abstract: Background: Formol-ether concentration technique is taken as a gold standard method to detect most intestinal parasites; however, because of its low safety and hazardous impact a need for better technique has a paramount importance. Objective: To evaluate a formol- acetone concentration method in comparison with the conventional direct iodine preparation and formol- ether concentration methods in detecting intestinal parasites. Methods: A total of 382 stool samples were collected from Tseda elementary school children, in 2006. Samples were processed and examined using formol-acetone concentration, the direct iodine stained smear, and formol-ether concentration methods. Results: Formol-ether detected 79.1% of parasites followed by formol-acetone (73.6%) and direct iodine preparation (50.3%). Statistical (P< 0.05) difference was observed for the detection of over all positivity of any parasites between the two concentration methods. However, the sensitivity, specificity, and positive predicative value of formol-acetone were 88.1%, 81.3%, and 94.7%, respectively respective to formol-ether method. Almost similar detection ability was also observed by the two concentration methods for A. lumbricoids, H. nana, T. trichuira, and S. stercoralis. However, there was difference in the detection rate of hookworm and S. mansoni. Conclusions: for safety and hazard free laboratory set up, this new method might be used as an alternative choice for formol-ether concentration method. [Ethiop. J. Health Dev. 2010;24(2):148-151]
Socioeconomic Factors Associated with Underweight and Stunting among Adolescents of Jimma Zone, South West Ethiopia: A Cross-Sectional Study
Huruy Assefa,Tefera Belachew,Legesse Negash
ISRN Public Health , 2013, DOI: 10.1155/2013/238546
Abstract: Background. Nutrition during adolescence plays an important role in the individual’s life. Socioeconomic status, age, sex, and mothers’ educational level are among the important determinant factors of nutritional status of adolescents. In this study, we test the competing hypotheses about the correlates of nutritional status among Ethiopian adolescents. Methods. We report a total of 2084 adolescents and univariate and multivariable linear regression were used to assess socioeconomic factors associated with underweight and stunting among adolescents. Results. Age, highest grade completed, job, and last attended in community school were positively associated with BMI for Age z-score and highest grade completed, household income, and job were positively associated with Height for Age z-score. However, male gender was negatively associated with BMI for Age z-score and male gender, last attended in community school, abdominal pain, and household size were negatively associated with Height for Age z-score. Conclusion. Age of the adolescents, gender, educational status, employment status, and type of last school attended are associated with underweight; gender, place of residence, household size, household income, educational status, employment status, type of last school attended, and abdominal pain are associated with stunting. The findings reflect socio-economic characteristics are associated with underweight and stunting. 1. Background of the study The world population is believed to have reached over 6.6 billion [1]. Adolescence is a particularly unique period in life because it is a time of intense physical, psychosocial, and cognitive development. Nutrition during adolescence plays an important role in the individual’s life. Increased nutritional needs to adolescents gain up to 50% of their adult weight, more than 20% of their adult height, and 50% of their adult skeletal mass [2]. There are different factors that affect nutritional status of adolescents. Socioeconomic status, age, sex, and mothers’ educational level are among the important determinant factors of nutritional status of adolescents [3–6]. Studies have shown that adolescent women from low economic status households were most affected by malnutrition and the higher the level of education, the lower the proportion of undernourished adolescent women, and rural adolescent women are more likely to suffer from chronic energy deficiency than adolescent women in urban areas. [7, 8]. There are only a handful of studies on adolescent malnutrition in developing countries—they indicate that younger
Immune restoration disease and changes in CD4+ T-cell count in HIV- infected patients during highly active antiretroviral therapy at Zewditu memorial hospital, Addis Ababa, Ethiopia
Kahsay Huruy, Afework Kassu, Andargachew Mulu, Yemataw Wondie
AIDS Research and Therapy , 2010, DOI: 10.1186/1742-6405-7-46
Abstract: A retrospective study of all HIV- infected patients starting HAART between September 1, 2005 and August 31, 2006 at Zewditu memorial hospital HIV clinic, Addis Ababa, Ethiopia was conducted. All laboratory and clinical data were extracted from computerized clinic records and patient charts.A total of 1166 HIV- infected patients with mean ± SD age of 36 ± 9.3 years were on HAART. IRD was identified in 170 (14.6%) patients. OIs diagnosed in the IRD patients were tuberculosis (66.5%, 113/170), toxoplasmosis (12.9%, 22/170), herpes zoster rash (12.9%, 22/170), Pneumocystis jirovecii pneumonia (4.1%, 7/170), and cryptococcosis (3.5%, 6/170). Of the 170 patients with IRD, 124 (72.9%) patients developed IRD within the first 3 months of HAART initiation. Low baseline CD4+ T-cell count (odds ratio [OR], 3.16, 95% confidence interval [CI], 2.19-4.58) and baseline extra pulmonary tuberculosis (OR, 7.7, 95% CI, 3.36-17.65) were associated with development of IRD. Twenty nine (17.1%) of the IRD patients needed to use systemic anti-inflammatory treatment where as 19(11.2%) patients required hospitalization associated to the IRD occurrence. There was a total of 8 (4.7%) deaths attributable to IRD.The proportion and risk factors of IRD and the pattern of OIs mirrored reports from other countries. Close monitoring of patients during the first three months of HAART initiation is important to minimize clinical deterioration related to IRD.Highly active antiretroviral therapy (HAART) improves the immune function and decreases morbidity, mortality and opportunistic infections (OIs) in HIV-infected patients [1,2]. However, the introduction of HAART presents new clinical problems, including adverse drug effects, and the event of diseases that are as the result of the restoration of the immune response. When clinical deterioration occurs during immune recovery and is associated with the host inflammatory response to pathogens, the clinical presentation has been described as immune restorat
Vitamin A deficiency during pregnancy of HIV infected and non-infected women in tropical settings of Northwest Ethiopia
Andargachew Mulu, Afework Kassu, Kahsay Huruy, Birhanemeskel Tegene, Gashaw Yitayaw, Masayo Nakamori, Nguyen Van Nhien, Assegedech Bekele, Yared Wondimhun, Shigeru Yamamoto, Fusao Ota
BMC Public Health , 2011, DOI: 10.1186/1471-2458-11-569
Abstract: In this cross-sectional study, blood samples were collected from 423 pregnant women and from 55 healthy volunteers who visited the University of Gondar Hospital. Serum concentration of vitamin A was measured by high performance liquid chromatography.After controlling for total serum protein, albumin and demographic variables, the mean ± SD serum vitamin A in HIV seropositive pregnant women (0.96 ± 0.42 μmol/L) was significantly lower than that in pregnant women without HIV infection (1.10 ± 0.45 μmol/L, P < 0.05). Likewise, the level of serum vitamin A in HIV seropositive non-pregnant women (0.74 ± 0.39) was significantly lower than that in HIV negative non-pregnant women (1.18 ± 0.59 μmol/L, P < 0.004). VAD (serum retinol < 0.7 μmol/L) was observed in 18.4% and 17.7% of HIV infected and uninfected pregnant women, respectively. Forty six percent of non-pregnant women with HIV infection had VAD while only 28% controls were deficient for vitamin A (P = 0.002).The present study shows that VAD is a major public health problem among pregnant women in the tropical settings of Northwest Ethiopia. Considering the possible implications of VAD during pregnancy, we recommend multivitamin (which has a lower level of vitamin A) supplementation in the care and management of pregnant women with or without HIV infection.Vitamin A deficiency (VAD) is known to be a significant public health problem around the world and it is particularly serious among women of reproductive age in South-East Asia and Africa [1-4]. It has now become evident that VAD in women has negative consequences on their health status as well as on their infants [3,4]. The link between VAD morbidity and mortality from infectious diseases [5] and non-infectious diseases [6-8] has been known for several years.VAD in pregnant women is associated with night blindness, severe anaemia, wasting, malnutrition, and reproductive and infectious morbidity [9], and increased risk of mortality 1-2 years following delivery [4].
Intestinal parasitosis and shigellosis among diarrheal patients in Gondar teaching hospital, northwest Ethiopia
Kahsay Huruy, Afework Kassu, Andargachew Mulu, Netsanet Worku, Teshome Fetene, Simon Gebretsadik, Fantahun Biadglegne, Yeshambel Belyhun, Abebe Muche, Aschalew Gelaw, Belay Anagaw, Sisay Yifru, Yemataw Wondie, Assegedech Bekele, Moges Tiruneh, Dieter Reissig, Feleke Moges
BMC Research Notes , 2011, DOI: 10.1186/1756-0500-4-472
Abstract: A cross-sectional study involving 384 consecutive diarrheal patients who visited Gondar teaching hospital, Gondar, Ethiopia from October 2006 to March 2007 was conducted. Stool specimens were collected and examined for intestinal parasites and enteropathogenic bacteria following standard parasitological and microbiological procedures.Intestinal parasites were diagnosed in 36.5% of the patients. The most frequently encountered protozoan parasite was Entamoeba histolytica/dispar (7.3%) followed by Giardia lamblia (5.0%), Cryptosporidium parvum (1.8%) and Isospora belli (1.3%). The dominant helminthic parasite identified was Ascaris lumbricoides (5.5%) followed by Strongyloides stercoralis and Schistosoma mansoni (3.1% each), hookworm infection (1.8%), and Hymenolepis species (1.3%). Multiple infections of intestinal parasites were also observed in 6.3% of the patients. Among the enteropathogenic bacteria Shigella and Salmonella species were isolated from 15.6% and 1.6%, respectively, of the patients. Escherichia coli O57:H7 was not found in any of the stool samples tested. Eighty eight percent and 83.3% of the Shigella and Salmonella isolates were resistant to one or more commonly used antibiotics, respectively.Intestinal parasitosis was higher in patients who live in rural area, in patients who were washing their hands after visiting toilet either irregularly with soap and without soap or not at all, in patients who used well and spring water for household consumption, and in patients who had nausea (P < 0.05). Statistically significant associations were also observed between Shigella infections and patients who were using well and spring water for household consumption, and patients who had dysentery and mucoid stool (P < 0.05).The high prevalence of intestinal parasites and Shigella species in diarrheic patients calls for institution of appropriate public health intervention measures to reduce morbidity and mortality associated with these diseases. The rational use
The Constrained Mean-Semivariance Portfolio Optimization Problem with the Support of a Novel Multiobjective Evolutionary Algorithm  [PDF]
K. Liagkouras, K. Metaxiotis
Journal of Software Engineering and Applications (JSEA) , 2013, DOI: 10.4236/jsea.2013.67B005

The paper addresses the constrained mean-semivariance portfolio optimization problem with the support of a novel multi-objective evolutionary algorithm (n-MOEA). The use of semivariance as the risk quantification measure and the real world constraints imposed to the model make the problem difficult to be solved with exact methods. Thanks to the exploratory mechanism, n-MOEA concentrates the search effort where is needed more and provides a well formed efficient frontier with the solutions spread across the whole frontier. We also provide evidence for the robustness of the produced non-dominated solutions by carrying out, out-of-sample testing during both bull and bear market conditions on FTSE-100.

Design of a Cantilever - Type Rotating Bending Fatigue Testing Machine  [PDF]
K. K. Alaneme
Journal of Minerals and Materials Characterization and Engineering (JMMCE) , 2011, DOI: 10.4236/jmmce.2011.1011078
Abstract: This research is centered on the design of a low–cost cantilever loading rotating bending fatigue testing machine using locally sourced materials. The design principle was based on the adaptation of the technical theory of bending of elastic beams. Design drawings were produced and components/materials selections were based on functionality, durability, cost and local availability. The major parts of the machine: the machine main frame, the rotating shaft, the bearing and the bearing housing, the specimen clamping system, pulleys, speed counter, electric motor, and dead weights; were fabricated and then assembled following the design specifications. The machine performance was evaluated using test specimens which were machined in conformity with standard procedures. It was observed that the machine has the potentials of generating reliable bending stress – number of cycles data; and the cost of design (171,000 Naira) was lower in comparison to that of rotating bending machines from abroad. Also the machine has the advantages of ease of operation and maintenance, and is safe for use.
K. Метешк?н,Х. Раковський
Information Technologies and Learning Tools , 2010,
Abstract: The results of Bologna process are investigated. It is underlined that theoretical – methodological bases of the Bologna process have been poorly developed. A scheme for master’s education both on requirements of separate states, and on requirements of EU is offered. Досл джуються п дсумки Болонського процесу. П дкреслю ться, що слабко розроблен теоретико-методолог чн основи Болонського процесу. Пропону ться схема навчання маг стр в, як для потреб окремих держав, так для потреб С.
Х.В. Раковський,Н.Х. Раковська,K.О. Метешк?н
Information Technologies and Learning Tools , 2010,
Abstract: The process and phenomena connected with the initiation of new methodological paradigm of the scientific and educational management in Ukraine has been investigated. The paradigm is conditioned by global tendencies of informatization, development of communicative means and integrative processes in education and science У статт досл джен процеси та явища, пов’язан з зародженням в Укра н ново методолог чно парадигми управл ння осв тою наукою, яка обумовлена глобальними тенденц ями нформатизац , розвитком комун кац йних засоб в, а також нтеграц йними процесами в осв т та науц .
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