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Search Results: 1 - 10 of 5929 matches for " Jung Yeon Shim "
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Distribution of Electromagnetic Force of Square Working Coil for High-Speed Magnetic Pulse Welding Using FEM  [PDF]
Ji-Yeon Shim, Bong-Yong Kang
Materials Sciences and Applications (MSA) , 2013, DOI: 10.4236/msa.2013.412109
Abstract:

Magnetic pulse welding process, one of high speed welding processes, uses electromagnetic force from discharged current through a working coil which develops a repulsive force between the induced currents flowing parallel and in the opposite direction in the pipe to be welded. For achieving the successful weldment and using this process, the design of working coil is the most important factor, because working coil has to generate a high-intensity magnetic field on the surface of the workpiece during the process. Therefore, the objective of this study is to analyze the distribution of electromagnetic force of square working coil for magnetic pulse welding. For this, FE-model has been developed to analyze the distribution of electromagnetic force; after that, distribution of electromagnetic force, results of numerical analysis and experimental results for verifying the developed FE-model were compared. A 3-dimensional electromagnetic FE-model has been developed using a general commercial computer program, ANSYS/EMAG code. The shape and material of square working coil were decided through literature surveys. For the experiment, an MPW equipment W-MPW manufactured by WELDMATE Co., Ltd. was employed

Epigenetic Inactivation of Heparan Sulfate (Glucosamine) 3-O-Sulfotransferase 2 in Lung Cancer and Its Role in Tumorigenesis
Jung-Ah Hwang, Yujin Kim, Seung-Hyun Hong, Jieun Lee, Yong Gu Cho, Ji-Youn Han, Young-Ho Kim, Joungho Han, Young Mog Shim, Yeon-Su Lee, Duk-Hwan Kim
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0079634
Abstract: Background This study was aimed at investigating the functional significance of heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (HS3ST2) hypermethylation in non-small cell lung cancer (NSCLC). Methodology/ Principal Findings HS3ST2 hypermethylation was characterized in six lung cancer cell lines, and its clinical significance was analyzed using 298 formalin-fixed paraffin-embedded tissues and 26 fresh-frozen tissues from 324 NSCLC patients. MS-HRM (methylation-specific high-resolution melting) and EpiTYPERTM assays showed substantial hypermethylation of CpG island at the promoter region of HS3ST2 in six lung cancer cell lines. The silenced gene was demethylated and re-expressed by treatment with 5-aza-2′-deoxycytidine (5-Aza-dC). A promoter assay also showed the core promoter activity of HS3ST2 was regulated by methylation. Exogenous expression of HS3ST2 in lung cancer cells H460 and H23 inhibited cell migration, invasion, cell proliferation and whereas knockdown of HS3ST2 in NHBE cells induced cell migration, invasion, and cell proliferation in vitro. A negative correlation was observed between mRNA and methylation levels of HS3ST2 in 26 fresh-frozen tumors tissues (ρ = -0.51, P = 0.009; Spearman’s rank correlation). HS3ST2 hypermethylation was found in 95 (32%) of 298 primary NSCLCs. Patients with HS3ST2 hypermethylation in 193 node-negative stage I-II NSCLCs with a median follow-up period of 5.8 years had poor overall survival (hazard ratio = 2.12, 95% confidence interval = 1.25–3.58, P = 0.005) compared to those without HS3ST2 hypermethylation, after adjusting for age, sex, tumor size, adjuvant therapy, recurrence, and differentiation. Conclusions/ Significance The present study suggests that HS3ST2 hypermethylation may be an independent prognostic indicator for overall survival in node-negative stage I-II NSCLC.
Discordance between Perceived and Actual Cancer Stage among Cancer Patients in Korea: A Nationwide Survey
Hye-Young Shim, Jong-Hyock Park, So-Young Kim, Dong Wook Shin, Ji-Yeon Shin, Bo Young Park, Jung-Sik Huh, Hee-Young Shin, Young Joo Won, Hong Gwan Seo
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0090483
Abstract: Purpose We assessed the accuracy of communication between doctors and patients by evaluating the consistency between patient perception of cancer stage and the medical records, and analyzed the most influential factors of incongruence among cancer patients at 10 cancer centers across Korea. Methods Information was gathered from cancer patients at the National Cancer Center and nine regional cancer centers located in every province of Korea between 1 July 2008 and 31 August 2008. Data were analyzed using Pearson's χ2 test and multivariate logistic regression analysis. Results The stages of cancer reported by the 1,854 patients showed a low degree of congruence with the stages given in medical records (k = 0.35, P<0.001). Only 57.1% of the patients had accurate knowledge of their cancer stage. In total, 18.5% underestimated their stage of disease, and the more advanced the cancer stage, the more likely they were to underestimate it, in order of local (14.2%), regional (23.7%), and distant (51.6%). Logistic regression analysis showed that congruence was lower in patients with cervical cancer (odds ratio [OR] = 0.51, 95% confidence interval [CI] = 0.30–0.87), recurrence (OR = 0.64, 95% CI = 0.50–0.83), and treatment at the National Cancer Center (OR = 0.53, 95% CI = 0.39–0.72). Conclusion There are knowledge gaps between patients' perceived and actual stage of cancer. Patients with cervical cancer, recurrence, and who received treatment at a regional cancer center showed less understanding of their cancer stage.
Synthesis and Electrochemical Characterization of Li2MnSiO4 with Different Crystal Structure as Cathode Material in Lithium Rechargeable Batteries  [PDF]
Joongpyo Shim, Sora Won, Gyungse Park, Ho-Jung Sun
Advances in Materials Physics and Chemistry (AMPC) , 2012, DOI: 10.4236/ampc.2012.24B048
Abstract:

Li2MnSiO4 with different crystal structure was synthesized by solid state reaction method. Their crystal structure and electrochemical properties have been characterized by X-ray diffraction and charge-discharge test. The material prepared at 900oC in N2 atmosphere had γ-phase and its crystal structure changed to β-phase by post-heating at 400oC in air after 900oC sintering. In electrochemical measurement, two materials (γ- and β-phase) showed ~3 and ~45mAh/g, respectively. The different capacities of these two materials might be due to the change of crystal structure.



Micromorphology and Ultrastructure of the Foot of the Equilateral Venus Gomphina veneriformis (Bivalvia: Veneridae)  [PDF]
Jung Jun Park, Jung Sick Lee, Yeon Gyu Lee, Jae Won Kim
CellBio (CellBio) , 2012, DOI: 10.4236/cellbio.2012.11002
Abstract: The shape and microscopic structure of the foot of the equilateral Venus, Gomphina veneriformis are described by light and electron microscopy along with the substrate conditions of their habitat. The habitat sediment of G. veneriformis is composed of sand (2 - 0.063 mm in diameter), mainly. The foot is wedge-shaped with multiple vertical furrows on the surface. Although the foot is composed of an epithelial layer, a connective tissue layer and a muscular layer, the boundary between the connective tissue and muscular layer is not clear. The epithelial layer was composed mostly of ciliated columnar epithelia and secretory cells. Epithelial cells forming the apical region of the fold were long columnar, while cells of the interfold were mostly short columnar. The cilia and microvilli were commonly observed on the free surface of epithelial cells, while tight junctions of apico-lateral aspect and membrane interdigitations were found between the epithelial cells. Secretory cells were found to contain acidic mucopolysaccharide, and were classified into two types in accordance with the shapes and ultrastructures of secretory granules. The muscle fibers were composed of thin and thick microfilaments, the proportions of which were 81.3% and 18.7%, respectively. It was determined that such morphology and structural characteristics of the foot of G. veneriformis would present advantageous conditions for borrowing into substrate and mobility.
A Compact Vertical Scanner for Atomic Force Microscopes
Jae Hong Park,Jaesool Shim,Dong-Yeon Lee
Sensors , 2010, DOI: 10.3390/s101210673
Abstract: A compact vertical scanner for an atomic force microscope (AFM) is developed. The vertical scanner is designed to have no interference with the optical microscope for viewing the cantilever. The theoretical stiffness and resonance of the scanner are derived and verified via finite element analysis. An optimal design process that maximizes the resonance frequency is performed. To evaluate the scanner’s performance, experiments are performed to evaluate the travel range, resonance frequency, and feedback noise level. In addition, an AFM image using the proposed vertical scanner is generated.
Constructing Cost-effective Anomaly Detection Systems for User Identification
Charlie Y. Shim,Jung Yeop Kim
Lecture Notes in Engineering and Computer Science , 2008,
Abstract:
Two Marine Sponges of the Family Ancorinidae (Demospongiae: Astrophorida) from Korea
Eun Jung Shim,Chung Ja Sim
Animal Systematics, Evolution and Diversity , 2013, DOI: http://dx.doi.org/10.5635/ased.2013.29.1.31
Abstract: Two sponges, Stelletta subtilis (Sollas, 1886) and Stryphnus sollasi n. sp., were collected from depth of 24-30 m at Jeju-do Island and Chuja-do Island by SCUBA diving from July 2003 to June 2010. The new species Stryphnus sollasi n. sp is similar with Stryphnus niger Sollas, 1886 in the composition of spicules, however they differ in colour and spicule size. This new species has smaller oxeas and larger oxyasters than those of S. niger. This new species has two size categories of oxyaster but S. niger has one size category of oxyaster. The colour of S. sollasi n. sp is white, but the latter puce black. Stelletta subtilis (Sollas, 1886) is first recorded in Korean fauna.
A New Species of the Genus Caminus (Astroporida: Geodiidae) from Korea
Eun Jung Shim,Chung Ja Sim
Animal Systematics, Evolution and Diversity , 2012, DOI: http://dx.doi.org/10.5635/ased.2012.28.3.208
Abstract: Caminus jejuensis n. sp was collected from depth of 20 m at Geomeunyeo, Seogwipo, Jejudo Island by a SCUBA diving from April 2004 to December 2008. This new species is similar to C. chinensis from China in the composition of spicules except for the spherasters and they differ in spicule size and growth form. This species has longer orthotriaenes and spherules, smaller sterrasters and oxyasters than those of C. chinensis. This species also has many spherasters in choanosome, but C. chinensis lacks. Morever, the new species is a massive shape with wrinkles, whereas C. chinensis is a club shape with smooth surface. Description and figures of the new species are provided.
Additive Effect between IL-13 Polymorphism and Cesarean Section Delivery/Prenatal Antibiotics Use on Atopic Dermatitis: A Birth Cohort Study (COCOA)
So-Yeon Lee, Jinho Yu, Kang-Mo Ahn, Kyung Won Kim, Youn Ho Shin, Kyung-shin Lee, Seo Ah Hong, Young-ho Jung, Eun Lee, Song-I Yang, Ju-hee Seo, Ji-Won Kwon, Byoung-Ju Kim, Hyo-Bin Kim, Woo-Kyung Kim, Dae Jin Song, Gwang Cheon Jang, Jung Yeon Shim, Soo-Young Lee, Ja-Young Kwon, Suk-Joo Choi, Kyung-Ju Lee, Hee Jin Park, Hye-Sung Won, Ho-Sung Yoo, Mi-Jin Kang, Hyung-Young Kim, Soo-Jong Hong
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0096603
Abstract: Background Although cesarean delivery and prenatal exposure to antibiotics are likely to affect the gut microbiome in infancy, their effect on the development of atopic dermatitis (AD) in infancy is unclear. The influence of individual genotypes on these relationships is also unclear. To evaluate with a prospective birth cohort study whether cesarean section, prenatal exposure to antibiotics, and susceptible genotypes act additively to promote the development of AD in infancy. Methods The Cohort for Childhood of Asthma and Allergic Diseases (COCOA) was selected from the general Korean population. A pediatric allergist assessed 412 infants for the presence of AD at 1 year of age. Their cord blood DNA was subjected to interleukin (IL)-13 (rs20541) and cluster-of-differentiation (CD)14 (rs2569190) genotype analysis. Results The combination of cesarean delivery and prenatal exposure to antibiotics associated significantly and positively with AD (adjusted odds ratio, 5.70; 95% CI, 1.19–27.3). The association between cesarean delivery and AD was significantly modified by parental history of allergic diseases or risk-associated IL-13 (rs20541) and CD14 (rs2569190) genotypes. There was a trend of interaction between IL-13 (rs20541) and delivery mode with respect to the subsequent risk of AD. (P for interaction = 0.039) Infants who were exposed prenatally to antibiotics and were born by cesarean delivery had a lower total microbiota diversity in stool samples at 6 months of age than the control group. As the number of these risk factors increased, the AD risk rose (trend p<0.05). Conclusion Cesarean delivery and prenatal antibiotic exposure may affect the gut microbiota, which may in turn influence the risk of AD in infants. These relationships may be shaped by the genetic predisposition.
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