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Search Results: 1 - 10 of 37254 matches for " Jun-Gyo Suh "
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Transcortical Alterations in - ATPase and Microtubule-Associated Proteins Immunoreactivity in the Rat Cortical Atrophy Model Induced by Hypoxic Ischemia
Jun-Gyo Suh,Sung-Jin An,Jae-Bong Park,Zae-Young Ryoo,Jeong Woong Lee,Yang-Seok Oh,Moo Ho Won,Tae-Cheon Kang
Neural Plasticity , 2002, DOI: 10.1155/np.2002.135
Abstract: To identify the chronological transcortical change in the contralateral hemisphere following ischemic insults, we investigated the changes in microtubule associated protein (MAP) and Na
Production of antibodies with peptide-CpG-DNA-liposome complex without carriers
Dongbum Kim, Sanghoon Kwon, Jae Rhee, Kwang Kim, Young-Eun Kim, Cheung-Seog Park, Myeong Choi, Jun-Gyo Suh, Doo-Sik Kim, Younghee Lee, Hyung-Joo Kwon
BMC Immunology , 2011, DOI: 10.1186/1471-2172-12-29
Abstract: We present that a particular form of natural phosphodiester bond CpG-DNA encapsulated in a specific liposome complex (Lipoplex(O)) induces potent immunomodulatory activity in humans as well as in mice. Additionally, Lipoplex(O) enhances the production of IgG2a specific to antigenic protein in mice. Most importantly, immunization of mice with several peptides co-encapsulated with Lipoplex(O) without carriers significantly induces each peptide-specific IgG2a production in a TLR9-dependent manner. A peptide-specific monoclonal antibody produced against hepatocellular carcinoma-associated antigen has functional effects on the cancer cells.Our overall results show that Lipoplex(O) is a potent adjuvant and that complexes of peptide and Lipoplex(O) are extremely useful for B cell epitope screening and antibody production without carriers. Therefore, our strategy may be promptly used for the development of therapeutic antibodies by rapid screening of potent B cell epitopes.Synthetic oligodeoxynucleotides (ODNs) and bacterial DNA containing unmethylated CpG dinucleotides flanked by specific base sequences (CpG-DNA) have significant immunomodulatory effects on B lymphocytes, macrophages, dendritic cells, and natural killer cells [1-4]. Experimental evidence suggests that CpG-DNA induces the regulation of Th1/Th2 immune responses, antigen-presenting cell activity, and immunoglobulin (Ig) isotype switching [5-7]. Therefore, CpG-DNA has gained attention for its potential use as an immune adjuvant and in therapeutics for allergic and infectious diseases [8,9].Phosphorothioate-modified types of CpG-DNA (PS-ODN), which are resistant to nuclease activity and can be efficiently delivered into cells [10,11], have been utilized in clinical applications [9]. The immunomodulatory activities of PS-ODN are enhanced by liposome-encapsulation [12-14]. However, several studies have suggested that PS-ODN induces backbone-related side effects, such as transient splenomegaly [15], lymphoid folli
Survival in Primary Carcinoma of the External and Middle Ear Is Strongly Dependent on Stage at Diagnosi  [PDF]
Toru Ugumori, Jun Hyodo, Naohito Hato, Kiyofumi Gyo
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2013, DOI: 10.4236/ijohns.2013.26046
Abstract: Conclusion: Early-stage detection of temporal bone carcinoma improves the survival rate. When detected at an advanced stage, predicted prognosis is poor even with a combination of surgery, radiotherapy and chemotherapy. Objectives: We evaluated treatment strategies and survival rates in cases of carcinomas of the external and middle ear. Method: Retrospective review of patients treated at Ehime University Hospital during the 32 years from 1977 to 2008. Subjects were 41 patients, consisting of 21 men and 20 women with a mean age of 63.2 years. Modified Pittsburgh staging system: stage I in 11 cases (27%), stage II in 4 (10%), stage III in 6 (15%) and stage IV in 20 (49%). Histopathology: squamous cell carcinoma (SCC) in 35 cases, adenoid cystic carcinoma (ACC) in 3, and adenocarcinoma (AC) in 3. Thirty-eight patients were treated by surgery. Radiation was added postoperatively in 23 patients. Three patients were treated by chemoradiotherapy. Results: The survival rate of carcinomas detected at an advanced stage was poor with a disease-specific 5-year survival rate of 100% in early-stage disease (stage I and II) versus 20.8% in stage III and 27.5% in stage IV disease, irrespective of histopathology of the tumor.
Optimization of the Sampling Periods and the Quantization Bit Lengths for Networked Estimation
Young Soo Suh,Young Sik Ro,Hee Jun Kang
Sensors , 2010, DOI: 10.3390/s100706406
Abstract: This paper is concerned with networked estimation, where sensor data are transmitted over a network of limited transmission rate. The transmission rate depends on the sampling periods and the quantization bit lengths. To investigate how the sampling periods and the quantization bit lengths affect the estimation performance, an equation to compute the estimation performance is provided. An algorithm is proposed to find sampling periods and quantization bit lengths combination, which gives good estimation performance while satisfying the transmission rate constraint. Through the numerical example, the proposed algorithm is verified.
Superbridge index of composite knots
Gyo Taek Jin
Mathematics , 2000,
Abstract: An upper bound of the superbridge index of the connected sum of two knots is given in terms of the braid index of the summands. Using this upper bound and minimal polygonal presentations, we give an upper bound in terms of the superbridge index and the bridge index of the summands when they are torus knots. In contrast to the fact that the difference between the sum of bridge indices of two knots and the bridge index of their connected sum is always one, the corresponding difference for the superbridge index can be arbitrarily large.
Packet Compression Ratio Dependent Spanning Tree for Convergecast  [PDF]
Changjin Suh, Jisoo Shin
Wireless Sensor Network (WSN) , 2010, DOI: 10.4236/wsn.201027062
Abstract: A convergecast is a popular routing in sensor networks. It periodically forwards collected data at every sensor node along a configured routing path to the outside of a sensor network via the base station (BS). To extend the lifetime of energy-limited sensor networks, many previous researches proposed schemes for data compression. However, few researches investigated the relation between packet compression ratio and spanning trees. We propose packet Compression ratio dependent Spanning Tree (CST) which can provide effective routing paths in terms of the tree length for all ranges of compression ratio f. CST is equivalent to the Shortest Path spanning Tree (SPT) which is optimum in the case of no-compression (f = 0) and is equivalent to the Minimum Spanning Tree (MST) in the case of full-compression (f = 1). CST outperforms SPT and MST for any range of f (0 < f < 1). Through simulation we show CST provides shorter paths than MST and SPT in terms of the tree length by 34.1% and 7.8% respectively. We confirm CST is very useful in convergecasts.
Quantum Cosmology Explains the General Galaxy-Black Hole Correlation  [PDF]
Paul K. Suh
International Journal of Astronomy and Astrophysics (IJAA) , 2012, DOI: 10.4236/ijaa.2012.22014
Abstract: The symmetric quantum physics of the Universe demonstrates that the massive black holes developing in the post-inflation big-bang prompt the formation of the host galaxies around them. A general correlation between the variety of galaxies and black holes develops, a specific example of which is the celebrated (but not understood) mass correlation between the host elliptical galaxies and their core black holes. The elucidations and predictions in this exposition are inclusive and far-reaching, resolving a myriad of yet unsolved problems and quandaries in the evolving Universe, among which are: how the general galaxy-black hole correlations are established; what is the role of the dark matter and energy in the formation of galaxies and stars; how the spiral galaxies with less predominant black holes are formed; how the early star forming globular cluster emerged with sparse dark matter; why some galaxy mergers give rise to the starbursts, while other mergers switch the star flourishing galaxies off into grave yards; and how could the Universe have wound up as sheets and filaments of galaxy clusters encompassing great voids.
Cultural models of female breasts and breast cancer among Korean women  [PDF]
Eunyoung E. Suh
Open Journal of Nursing (OJN) , 2013, DOI: 10.4236/ojn.2013.35055
Abstract:

Although a great many qualitative descriptions of the experience of having breast cancer exist, they overwhelmingly represent experiences of women in Western cultures and are based on assumptions that stem from Western individualism. This study explores and describes cultural models shared by a group of non-Western women, South Koreans, in reference to female breasts and breast cancer. The hermeneutic phenomenology-grounded qualitative study was conducted with 40 Korean women, between 23 and 81 years of age, half of whom were breast cancer survivors. The analysis elicited two cultural models, both characterized in terms of physical relationships to others (as opposed to the woman’s individual or independent view of her body): a breast-feeding mother to a child and an attractive wife to a husband. Female breasts are interpreted as a medium that connects women to roles as mothers and wives. Breast cancer can lead women to detach from their previous relational and role-oriented identities. Cultural traditions, cultural concepts, and culture-related health beliefs in Korea are interwoven deeply in the women’s stories about breasts, as a gendered organ, and its disease. The findings suggest that understanding indigenous cultural models should precede any supportive breast cancer care for women from non-Western cultural backgrounds. 

Bacterial Inactivation of Wound Infection in a Human Skin Model by Liquid-Phase Discharge Plasma
Paul Y. Kim, Yoon-Sun Kim, Il Gyo Koo, Jae Chul Jung, Gon Jun Kim, Myeong Yeol Choi, Zengqi Yu, George J. Collins
PLOS ONE , 2011, DOI: 10.1371/journal.pone.0024104
Abstract: Background We investigate disinfection of a reconstructed human skin model contaminated with biofilm-formative Staphylococcus aureus employing plasma discharge in liquid. Principal Findings We observed statistically significant 3.83-log10 (p<0.001) and 1.59-log10 (p<0.05) decreases in colony forming units of adherent S. aureus bacteria and 24 h S. aureus biofilm culture with plasma treatment. Plasma treatment was associated with minimal changes in histological morphology and tissue viability determined by means of MTT assay. Spectral analysis of the plasma discharge indicated the presence of highly reactive atomic oxygen radicals (777 nm and 844 nm) and OH bands in the UV region. The contribution of these and other plasma-generated agents and physical conditions to the reduction in bacterial load are discussed. Conclusions These findings demonstrate the potential of liquid plasma treatment as a potential adjunct therapy for chronic wounds.
Quadrisecant approximation of hexagonal trefoil knot
Gyo Taek Jin,Seojung Park
Mathematics , 2010,
Abstract: It is known that every nontrivial knot has at least two quadrisecants. Given a knot, we mark each intersection point of each of its quadrisecants. Replacing each subarc between two nearby marked points with a straight line segment joining them, we obtain a polygonal closed curve which we will call the quadrisecant approximation of the given knot. We show that for any hexagonal trefoil knot, there are only three quadrisecants, and the resulting quadrisecant approximation has the same knot type.
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