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Search Results: 1 - 10 of 778 matches for " Julius Benicky "
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Telmisartan directly ameliorates the neuronal inflammatory response to IL-1β partly through the JNK/c-Jun and NADPH oxidase pathways
Tao Pang, Juan Wang, Julius Benicky, Enrique Sanchez-Lemus, Juan M Saavedra
Journal of Neuroinflammation , 2012, DOI: 10.1186/1742-2094-9-102
Abstract: SK-N-SH human neuroblasts and primary rat cortical neurons were pretreated with telmisartan followed by exposure to IL-1β. Gene expression was determined by reverse transcriptase (RT)-PCR, protein expression and kinase activation by western blotting, NADPH oxidase activity by the lucigenin method, prostaglandin E2 (PGE2) release by enzyme immunoassay, reactive oxygen species (ROS) generation by the dichlorodihydrofluorescein diacetate fluorescent probe assay, and peroxisome proliferator-activated receptor gamma (PPARγ) involvement was assessed with the antagonists GW9662 and T0070907, the agonist pioglitazone and the expression of PPARγ target genes ABCG1 and CD36.We found that SK-N-SH neuroblasts expressed AT1 but not AT2 receptor mRNA. Telmisartan reduced IL-1β-induced cyclooxygenase-2 (COX-2) expression and PGE2 release more potently than did candesartan and losartan. Telmisartan reduced the IL-1β-induced increase in IL-1R1 receptor and NADPH oxidase-4 (NOX-4) mRNA expression, NADPH oxidase activity, and ROS generation, and reduced hydrogen peroxide-induced COX-2 gene expression. Telmisartan did not modify IL-1β-induced ERK1/2 and p38 mitogen-activated protein kinase (MAPK) phosphorylation or nuclear factor-κB activation but significantly decreased IL-1β-induced c-Jun N-terminal kinase (JNK) and c-Jun activation. The JNK inhibitor SP600125 decreased IL-1β-induced PGE2 release with a potency similar to that of telmisartan. The PPARγ agonist pioglitazone reduced IL-1β-induced inflammatory reaction, whereas telmisartan did not activate PPARγ, as shown by its failure to enhance the expression of the PPARγ target genes ABCG1 and CD36, and the inability of the PPARγ antagonists GW9662 and T0070907 to modify the effect of telmisartan on COX-2 induction. The effect of telmisartan on IL-1β-stimulated COX-2 and IL-1R1 mRNA expression and ROS production was replicated in primary rat cortical neurons.Telmisartan directly ameliorates IL-1β-induced neuronal inflammatory respon
Real Time Motion Data Preprocessing
Peter Benicky, Ladislav Juri ica
Journal of Electrical Engineering , 2010, DOI: 10.2478/v10187-010-0035-2
Abstract: There is a lot of redundant data for image processing in an image, in motion picture as well. The more data for image processing we have, the more time is needed for preprocessing it. That is why we need to work with important data only. In order to identify or classify motion, data processing in real time is needed.
Some Characteristics of a Plant Growth Promoting Enterobacter sp. Isolated from the Roots of Maize  [PDF]
Frank Ogbo, Julius Okonkwo
Advances in Microbiology (AiM) , 2012, DOI: 10.4236/aim.2012.23046
Abstract: Some properties of an Enterobacter sp. isolated from the roots of maize are described. Isolation was carried out using the semisolid enrichment culture technique and subsequent plating, both on nitrogen free biotin medium. Morphological, biochemical and phylogenetic characterization using the MicroSeqTM 16S rDNA technique were employed in identification of isolate, which was revealed to be closest matched at 99.4% with Enterobacter asburiae. The isolate possessed properties of plant growth promoting bacteria. Thus, it produced indole-3-acetic, plant polymer hydrolyzing enzymes, pectinase and cellulase as well as ammonia in vitro. The isolate grew well in the presence of both 3% NaCl and 10 μg of streptomycin. In plate bioassays, isolate promoted the germination of both maize and rice seeds as well as root and lateral root growth resulting in weight increases of seedlings over their controls. Experiments to quantify ability of isolate to promote plant growth was performed using hydroponics solutions and as appropriate, an inoculum of the isolate. Pot experiments were also employed. Results from these studies showed that isolate enhanced nitrogen accumulation and significantly (p < 0.05), improved the growth of maze seedlings over controls. Isolate has potential for utilizetion as inocula for sustainable production of cereals.
To Harmonise or Not to Harmonise?: The Case of Cross-national Biotechnology Governance in Southern Africa
Mugwagwa,Julius;
Journal of technology management & innovation , 2011, DOI: 10.4067/S0718-27242011000300003
Abstract: this paper is based on a study which investigated both existing and new regulatory responses to food emergencies and bigger challenges presented by modern gene-based biotechnologies. in particular, this paper looks at the challenge of cross-national cooperation in regulation of these technologies in southern africa. one response to this challenge which has dominated policy agendas in the region for a long time, and with more prominence after the 2002-2003 food emergency, is that of harmonisation of national biosafety regulatory systems. harmonisation is touted by its promoters as one way in which countries can buttress weaker national and sub-national regulatory capacities, and develop synergies that will place them in a strong position to deal with the dynamic challenges presented by modern biotechnologies. the desire for cross-national cooperation in biotechnology management was investigated from the broader perspective of policy convergence, with harmonization being but one of the mechanisms towards the policy convergence. a number of factors facilitating or inhibiting policy convergence were identified, including but not limited to cultural, institutional, socio-economic and policy community attributes. the paper concludes that an understanding of these factors is crucial if grounded empirical and theoretical proposals on cross-national policy convergence are to be advanced.
Gender differentiation in Daily Farm Wage Rates in Abuja, Nigeria
A Julius
Journal of Agricultural Extension , 2012,
Abstract: The main objective of the study was to determine if significant difference existed in gender daily wage rates (wage rate/day) in farm production activities. Multi-stage technique was used for sample selection while structured questionnaires were used for data collection. A total of 168 farmers were randomly interviewed in four Agricultural Zones (42 respondents in each agricultural zone). Data were analyzed using two way mixed factorial analysis of variance and mean separation was done at 5% probability level. Results revealed that there was significant difference (P < 0.05) in the gender daily wage rates. The daily wage paid to an adult male (N950 = $ 6.47) was significantly higher than the wage paid to an adult female (N692.08 = $ 4.55), young male (N683.33 = $4.73) and young female (N562 = $ 3.70). Young females received the least daily wage. Generally, the grand mean daily wage was N734.82 ($ 4.86). Furthermore, there was significant (P < 0.05) main effect of location meaning that there were locational differences in the average daily wage rate. The Eastern Agricultural Zone had the highest daily wage (N798.94) On the contrary, there was no significant (P > 0.05) interaction effect between gender daily wage rates and locations. Based on the findings, the paper concluded that there was significant difference in gender daily wage rates. It was recommended that the study should be replicated in other places for cross-validation purposes.
Significant Factors Affecting Patronage of Health Facilities by Rural Dwellers in Owo Region, Nigeria
Julius Olujimi
The Social Sciences , 2013,
Abstract: Infrastructure has become ubiquitous theme in a variety of areas of the policy debate. For instance, a number of studies have argued that generalized access to infrastructure services plays a key role in helping to reduce income inequality and enhancing productivity. Health care facility is one of these infrastructure. Paradoxically, the inadequate provision of infrastructure is more pronounced in the rural areas that habour greater proportion of the Nigerian population than the urban area. While frantic efforts are being made in providing for more infrastructure, it is therefore necessary to encourage adequate patronage of the available infrastructure particularly health facilities by the rural dwellers. This study reports the findings of a study that looked into the significant factors affecting the patronage of health care facilities by rural dwellers in Owo region, Nigeria. The study utilized a set of questionnaire designed to collect data on the health-seeking behaviour of 348 rural dwellers randomly selected from 22 rural settlements in the region. The study identified 20 health consumer variables that were fitted into regression model. Using a step-wise regression model, it concludes that only nine (9) of the 20 variables significantly affected the patronage of health care facilities by the rural dwellers in the region. Finally, the paper gives suggestions that would enhance these factors in the promotion of patronage of health care facilities in the region in particular and Nigeria in general which are adaptable to most developing countries of the World.
Amicus in Spiritu Christi – die Rezeption des Laelius in einer Kloster gemeinschaft des 12.Jahrhunderts: Aelred von Rievaulx. Amicus in Spiritu Christi – Cicerono Lelijaus recepcija XII a. vienuolijoje: Aelredas i Rievaulx
Kerstin Julius
Literatura , 2010,
Abstract: Straipsnyje aptariama domi Cicerono traktato Laelius de amicitia recepcija XII am iaus cisters vienuolyno vienuolio Aelredo i Rievaulx kūrinyje. D mes pa-traukia pirmiausia pats faktas, kad svarstyti draugyst s kategorij ir nustatyti jos apibr im krik ion kv p pagoni kosios literatūros altinis ir kad autorius nepaiso viduram iams būdingos nuostatos, jog vienuoliai turi labai kriti kai vertinti pagoni kūrinius ir nesiremti jais kaip autoritetais. Aelredo i Rievaulx kūrinys i siskiria ir tuo, kad jame kalbama apie draugyst , per engian i prastos krik ioni kosios meil s ribas, apibr tas v. Benedikto reguloje. Straipsnyje siekiama rodyti, kad tarp Aelredo i Rievaulx dialogo ir Cicerono kūrini yra daug stiliaus ir id j pana um , ypa suvokiant s vok virtus, kuri, Aelredo nuomone, yra esmin draugyst s prielaida. Siekdamas suderinti Cicerono pateikt draugyst s apibr im (De am. 20: Amicitia est rerum humanarum et divinarum cum benevolentia et caritate consensio) su savo gyvenimo patirtimi ir vienuolyno kultūrine aplinka, Aelredas sukuria sav j amicitia spiritalis koncepcij , pasak kurios, tikroji draugyst gali būti tik sakralioje vienuolyno aplinkoje.
Einstein-Riemann Gravity on Deformed Spaces
Julius Wess
Symmetry, Integrability and Geometry : Methods and Applications , 2006,
Abstract: A differential calculus, differential geometry and the E-R Gravity theory are studied on noncommutative spaces. Noncommutativity is formulated in the star product formalism. The basis for the gravity theory is the infinitesimal algebra of diffeomorphisms. Considering the corresponding Hopf algebra we find that the deformed gravity is based on a deformation of the Hopf algebra.
'Digging [D]eeper than the eye approves': oral histories and their use in the Digging Deeper exhibition of the district Six Museum
Chrischené Julius
Kronos (Bellville) , 2008,
Abstract:
Effects of Farmers’ Level of Education and Cooperative Membership on Access to Agricultural Extension Services in Abuja, Nigeria
Ajah Julius
Trends in Agricultural Economics , 2012,
Abstract: The study examined the effects of farmers’ level of education and cooperative membership on access to extension services in Abuja. A purposeful technique was adopted for sample selection while semi-structured questionnaires were used for data collection. A sample of 240 farmers made up of 30 cooperative and 30 non-cooperative farmers who had no formal education, 30 cooperative and 30 non-cooperative farmers who had primary school education, 30 cooperative and 30 non-cooperative farmers who had secondary school education and 30 cooperative and 30 non-cooperative farmers who had post secondary school education were used for the study. Two-way analysis of variance was used for data analysis. Results indicated that there was no significant difference (p>0.05) in cooperative and non-cooperative farmers’ access to extension services but the mean responses indicated that cooperative farmers had, slightly, more access to extension services more than non-cooperative farmers. Similarly, farmers’ level of education did not significantly affect (p>0.05) access to extension services although, the mean response value for farmers who had no formal school education but were members of cooperative societies was higher compared with others. Furthermore, there was no significant (p>0.05) interaction effect of cooperative membership and farmers’ level of education on access to extension services. Based on the findings, the paper concluded that farmers’ level of education and cooperative membership did not affect access to extension services.
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