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Search Results: 1 - 10 of 114967 matches for " Judith;Monta?o-Loza "
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Patogénesis de la hipertensión portal
Montao-Loza, Aldo;Meza-Junco, Judith;
Revista de investigación clínica , 2005,
Abstract: it is now well established that portal hypertension is not a purely mechanical phenomenon. primary hemodynamic alterations develop in the hepatic and systemic circulatory systems; these alterations in combination with mechanical factors contribute to the development of portal hypertension. in the hepatic circulation, these hemodynamic alterations are characterized by vasoconstriction and impaired hepatic vasodilatory responses, whereas in the systemic circulation, particularly in the splanchnic bed, vessels are hyperemic with increased flow. thus, an increase in intrahepatic resistance in conjunction with increased portal venous inflow, mediated through splanchnic dilation, contributes to the development of portal hypertension. the ensuing development of elevated flow and transmural pressure through collateral vessels from the hypertensive portal vasculature into the lower pressure systemic venous circulation accounts for many of the complications, such as bleeding esophageal varices, observed with portal hypertension. the importance of the primary vascular origin of portal hypertension is emphasized by the utility of current therapies aimed at reversing these hemodynamic alterations, such as nitrates, which reduce portal pressure through direct intrahepatic vasodilatation, and fi blockers and octreotide, which reduce splanchnic vasodilatation and portal venous inflow. new evidence concerning relevant molecular mechanisms of contractile signaling pathways in hepatic stellate cells and the complex regulatory pathways of vasoactive molecules in liver endothelial cells makes a better understanding of these processes essential for developing further experimental therapies for portal hypertension. this article examines the current concepts relating to cellular mechanism that underlie the hemodynamic alterations that characterize and account for the development of portal hypertension.
Bases moleculares del cáncer
Meza-Junco, Judith;Montao-Loza, Aldo;Aguayo-González, Alvaro;
Revista de investigación clínica , 2006,
Abstract: cancer is a group of diseases characterized by an autonomous proliferation of neoplastia cells which have a number of alterations, including mutations and genetic instability. cellular functions are controlled by proteins, and because these proteins are encoded by dna organized into genes, molecular studies have shown that cancer is a paradigm of acquired genetic disease. the process of protein production involves a cascade of several different steps, each with its attendant enzymes, which are also encoded by dna and regulated by other proteins. most steps in the process can be affected, eventually leading to an alteration in the amount or structure of proteins, which in turn affects cellular function. however, whereas cellular function may be altered by disturbance of one gene, malignant transformation is thought to require two or more abnormalities occurring in the same cell. although there are mechanisms responsible for dna maintenance and repair, the basic structure of dna and the order of the nucleotide bases can be mutated. these mutations can be inherited or can occur sporadically, and can be present in all cells or only in the tumor cells. at the nucleotide level, these mutations can be substitutions, additions or deletions. several of the oncogenes discussed below, including the pb3, c-fms, and ras genes, can be activated by point mutations that lead to aminoacid substitution in critical portions of the protein. this article examines the current concepts relating to cellular mechanism that underlie the molecular alterations that characterize the development of cancer.
Efecto del drenaje biliar preoperatorio en la evolución posquirúrgica de la pancreatoduodenectomía
Montao-Loza, Aldo;Meza-Junco, Judith;Chan-Nu?ez, Carlos;Robles-Díaz, Guillermo;
Revista de investigación clínica , 2005,
Abstract: background/aim. there are theoretic arguments in favor and against biliary drainage before the pancreatoduodenectomy. most of the studies failed to show any beneficial effect of this aproach whereas others even reported an increased postoperative morbidity related with biliary drainage. therefore, the role of preoperative biliary drainage remains controversial. so, we decided to analyze our own results in a series of patients undergoing pancreatoduodenectomy in order to determine the association between preoperative biliary drainage and postoperative outcome. patients and methods. we analyzed 109 patients undergoing pancreatoduodenectomy between january 1990 and may 2003. patients were classified in 3 groups: group 1 (n = 64) patients without preoperative biliary drainage, group 2 (n = 27) patients who underwent preoperative biliary drainage with sphincterotomy and stent placement, and group 3 (n = 18) only sphincterotomy. demographic characteristics, surgical risk, comorbility, type of surgery, pathology and biochemical parameters were analyzed. we also, stratified patients with and without cholestasis (total bilirubin > 3mg/dl), and divided patients in two groups: with biliary drainage and without biliary drainage. surgical and medical complications, the frequency of patients with at least one complication (global morbidity) and mortality were compared between groups. kruskatwallis, mann-whitney u, and fisher tests were used for the analysis of categorical and dimensional variables. results. the most frequent postoperative diagnoses were biliopancreatic tumors. global postoperative morbidity and mortality were 40% (n = 44) and 10% (n = 11), respectively. the frequency of surgery and medical complications were no significantly different among the 3 groups. however, when only patients with cholestasis were analyzed (n = 65), there was a lower frequency of surgical complications and global postoperative morbidity in patients with preoperative biliary drainage (p = 0.
Endoscopic retrograde cholangiopancreatography in the elderly
ávila-Fu?es, José Alberto;Montao-Loza, Aldo;Zepeda-Gómez, Sergio;Meza-Junco, Judith;Melano-Carranza, Efrén;Valdovinos-Andraca, Francisco;Valdovinos-Díaz, Miguel A.;Ponce de León-Rosales, Sergio;
Revista de investigación clínica , 2005,
Abstract: background. endoscopic retrograde cholangiopancreatography (ercp) is a widely used technique for the diagnosis and treatment of biliary and pancreatic diseases. objective. to know the complication rate of ercp in the elderly. patients and methods. patient files who underwent ercp were reviewed and were divided into two groups: aged 65 and older (group 1) and less than 65 years (group 2). sociodemographic variables, prophylactic antibiotic use, indications for ercp and outcomes were assessed. results. mean age in group 1 was 72.9 years and 41.7 years in group 2. group 1 had more comorbidity (p < 0.001). the most frequent indication for the procedure was obstructive jaundice in both groups (63% versus 44%; p = 0.002). malignancy was more frequent as a cause of biliary obstruction in group 1 (45% versus 21%; p < 0.001). ercp was performed once in 76% in group 1 and 93% in group 2 (p = 0.001). prophylactic antibiotics were used more frequently in group 1 (84% versus 60%; p < 0.001). there were no differences between groups regarding infectious complications (p = 0.700). there was no difference in mortality rates between groups. conclusion. ercp is a safe procedure in elderly patients. the elderly frequently have more comorbidity. nevertheless, the complication and mortality rates did not differ in this study. it is noteworthy that elderly patients received prophylactic antibiotics more frequently than younger patients but infectious complications were not different. the patients should not be excluded from ercp based on their age.
Efecto de la administración de indometacina rectal sobre los niveles séricos de amilasa posteriores a colangiopancreatografía retrógrada endoscópica y su impacto en la aparición de episodios de pancreatitis secundaria Effect of the rectal administration of indomethacin on amylase serum levels after endoscopic retrograde cholangiopancreatography, and its impact on the development of secondary pancreatitis episodes
A. Montao Loza,X. Rodríguez Lomelí,J. E. García Correa,C. Dávalos Cobián
Revista Espa?ola de Enfermedades Digestivas , 2007,
Abstract: Introducción: hiperamilasemia y pancreatitis aguda representan las complicaciones mayores más frecuentes posteriores a colangiopancreatografía retrógrada endoscópica (CPRE), apareciendo en 1-30% de los casos. Objetivo: determinar la incidencia de hiperamilasemia y pancreatitis posterior a CPRE y evaluar la utilidad de indometacina rectal para la prevención de estos. Material y métodos: ensayo clínico controlado. Durante un periodo de 12 meses se incluyeron 150 pacientes. Estos fueron divididos en grupo de estudio (n = 75), a quienes se administró indometacina rectal 100 mg 2 horas previas al procedimiento, y control (n = 75) que recibió glicerina. Dos horas posteriores a la CPRE se determinó el nivel de amilasa sérica y se clasificaron en: 0 ≤ 150 UI/l, 1 = 151-599 UI/l, 2 ≥ 600 UI/l. Los episodios de pancreatitis clínica se cuantificaron y clasificaron de acuerdo a los criterios de Ranson. Resultados: distribución por género: 100 mujeres y 50 hombres. Edad media: 55,37 ± 18,0 para el grupo de estudio y 51,1 ± 17,0 para el control. El diagnóstico de patología benigna se presentó en 56 (74,7%) casos del grupo de estudio y 59 (78,7%) del control. Posterior al procedimiento, 13 (17,3%) pacientes del grupo experimental y 28 (37,3%) del control desarrollaron hiperamilasemia (p < 0,05). Se encontró hiperamilasemia > 600 UI/l en 3 pacientes del grupo de estudio y 10 del control (p = 0,001). Se detectó pancreatitis leve en 5,3% de los pacientes del grupo de estudio y 16% del control (p < 0,05). No hubo mortalidad ni eventos adversos. Conclusiones: indometacina rectal previo a CPRE disminuye el riesgo de hiperamilasemia y pancreatitis. La indometacina es accesible, de bajo costo con mínimos o nulos efectos secundarios. Background: hyperamylasemia and acute pancreatitis represent the most frequent major complication after endoscopic retrograde cholangiopancreatography (ERCP), developing in 1-30% of cases. Objective: to determine the incidence of hyperamylasemia and acute pancreatitis after ERCP, and to assess the utility of rectal indomethacin to prevent these events. Material and methods: a randomized clinical trial. During a 12-month period 150 patients were included. They were divided up into a study group (n = 75), where 100 mg of rectal indomethacin were administered 2 hours prior to the procedure, and a control group (n = 75), which received rectal glycerin. Two hours after ERCP serum amylase levels were measured and classified as follows: 0 ≤ 150 IU/L, 1 = 151-599 IU/L, 2 ≥ 600 IU/L. Clinical pancreatitis episodes were quantified and classified according t
Efecto de la administración de indometacina rectal sobre los niveles séricos de amilasa posteriores a colangiopancreatografía retrógrada endoscópica y su impacto en la aparición de episodios de pancreatitis secundaria
Montao Loza,A.; Rodríguez Lomelí,X.; García Correa,J. E.; Dávalos Cobián,C.; Cervantes Guevara,G.; Medrano Mu?oz,F.; Fuentes Orozco,C.; González Ojeda,A.;
Revista Espa?ola de Enfermedades Digestivas , 2007, DOI: 10.4321/S1130-01082007000600005
Abstract: background: hyperamylasemia and acute pancreatitis represent the most frequent major complication after endoscopic retrograde cholangiopancreatography (ercp), developing in 1-30% of cases. objective: to determine the incidence of hyperamylasemia and acute pancreatitis after ercp, and to assess the utility of rectal indomethacin to prevent these events. material and methods: a randomized clinical trial. during a 12-month period 150 patients were included. they were divided up into a study group (n = 75), where 100 mg of rectal indomethacin were administered 2 hours prior to the procedure, and a control group (n = 75), which received rectal glycerin. two hours after ercp serum amylase levels were measured and classified as follows: 0 ≤ 150 iu/l, 1 = 151-599 iu/l, 2 ≥ 600 iu/l. clinical pancreatitis episodes were quantified and classified according to ranson's criteria. results: gender distribution: 100 women and 50 men. mean age: 55.37 ± 18.0 for the study group, and 51.1 ± 17.0 for the control group. a diagnosis of benign pathology was present in 56 (74.7%) cases in the study group, and 59 (78.7%) controls. after ercp 13 (17.3%) patients in the study group and 28 (37.3%) in the control group developed hyperamylasemia (p ≤ 0.05). hyperamylasemia > 600 iu/l was found in 3 patients in the study group, and in 10 in the control group (p = 0.001). mild pancreatitis was detected in 4 (5.3%) patients in the study group, and in 12 (16%) patients in the control group (p = 0.034). there were no deaths or adverse drug reactions. conclusions: rectal indomethacin before ercp decreases the risk of hyperamylasemia and pancreatitis. indomethacine is a feasible, low-cost drug with minimal or nil side effects.
Sand Waves Generation: A Numerical Investigation of the Infiernillo Channel in the Gulf of California  [PDF]
Yovani Montao Ley, Noel Carbajal
Open Journal of Marine Science (OJMS) , 2016, DOI: 10.4236/ojms.2016.63035
Abstract: The effect of the coastal geometry on sand bed forms generation has been investigated for a tidal dominated area. Different hypothetical geometries of coastal channels with flat bottoms and unlimited sediment availability were exposed to strong oscillatory tidal currents to simulate the interaction of hydrodynamics and the bedload sediment transport. The hypothetical geometries stand for the idealization of the principal geographic features of the Infiernillo Channel, a coastal area of the Gulf of California where sandbanks and sand waves have been observed. A depth integrated hydrodynamic-numerical model and a parameterized formula to estimate the bedload sediment transport were applied coupled with a sediment conservation equation to determine the sea bottom morphodynamics. Model predictions in the Infiernillo Channel were compared to available satellite imagery. This investigation demonstrates that a vertical integrated numerical model is able to reproduce the development of incipient sand waves that exist in the Infiernillo Channel. Incipient sandbanks and shoals were also simulated. Sand waves with wavelengths of about 200 m were calculated on the same locations where sand waves actually exist. A crucial finding of this research was to show that the geometry of a shallow water basin and the presence of tidal velocity gradients associated with abrupt changes in the coastline alignment were critical in determining the sand-bed pattern generation. We demonstrate that a vertical variation of tidal currents is not necessary to generate sand waves.
Periodismo ambiental en Canal Sur Televisión
Lic. Miguel Montao Montao
Revista Latina de Comunicación Social , 1999,
Abstract: El autor estudia el origen histórico del periodismo ambiental, la evolución en Espa a y Andalucía y su aparición en Canal Sur TV Realiza un análisis sobre la información medioambiental, especialidad del periodismo que en la década de los noventa despierta nuevamente gran interés entre el público. La televisión autonómica ha dedicado, desde su creación numerosos programas sobre el medio ambiente. Actualmente sus Servicios Informativos tienen la sección Medio Ambiente. De la importancia que se concede a este tipo de información es un buen ejemplo el programa Tierra y Mar , que incorpora progresivamente noticias medioambientales, referidas a la educación ambiental, el mantenimiento y recuperación de la biodiversidad y la presentación de modelos de conducta respetuosos.
Medio ambiente, empresa y periodismo ambiental. El caso de Canal Natura y las noticias sobre medio ambiente en Andalucía
Dr. Miguel Montao Montao
Revista Latina de Comunicación Social , 2000,
Abstract: La revolución industrial del siglo XIX provocó un salto en la evolución de la humanidad sin precedentes, a la que siguieron otras revoluciones como la nuclear y en este final de milenio la de la comunicación. Hoy el progreso se mide no sólo por el beneficio económico que produce una determinada actividad, sino que en el balance intervienen de forma decisiva el respeto que la gestión de un recurso tiene por el medio ambiente.
LA PALMA AFRICANA EN EL PACíFICO COLOMBIANO: SU ILEGALIDAD, CONSECUENCIAS Y VIOLACIóN DE DERECHOS TERRITORIALES
Arboleda Montao,Nixon;
Luna Azul , 2008,
Abstract: the great biodiversity present in the colombian pacific coast has been and is being devastated by the agroindustry of african palm (revitalized by the biofuels boom). additionally, severe problems regarding the violation of territorial rights (protected by law 70 of 1993 and the 1991 political constitution) have arisen, as well as displacement and changes in the life conditions of the local community (mostly afro-colombian). this pacific coast community has been denied the possibility of creating their own development.
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