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Search Results: 1 - 10 of 228134 matches for " Juan Gabriel;Mancilla Díaz "
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Los receptores dopaminérgicos D2/D3 hipotalámicos participan en la regulación del comportamiento alimentario
Tejas Juárez, Juan Gabriel;Mancilla Díaz, Juan Manuel;Florán Gardu?o, Benjamín;Escartín Pérez, Rodrigo Erick;
Revista mexicana de análisis de la conducta , 2010,
Abstract: dopamine is a neurotransmitter strongly involved in the feeding behavior regulation. it has been reported that different dopamine receptor agonists inhibited voluntary food intake, nevertheless, dopamine depletion induced intense hypophagia. current knowledge of d2 receptors and d3 mrna expression in the paraventricular nucleus of the hypothalamus (pvn) suggests that d2-like receptors may be playing a main role in the dopaminergic feeding behavior regulation. the aim of the present study was to evaluate the effects of paraventricular d2/d3 receptor activation on food intake and behavioral satiety sequence (bss) in rats. male wistar rats (220-240 g) were intra-pvn injected with d2/d3/d4 receptor agonists and/or antagonists, and food intake and bss were evaluated during 2 hours (dark phase of light cycle). the obtained results showed that intra-pvn d2/d3 activation significantly decreased food intake without disrupting the bss. the above results strongly suggest that hypothalamic dopamine induces inhibitory effects on food intake via d2/d3 receptors in the pvn.
Obesidad: factor de riesgo para esteatohepatitis y fibrosis hepática
Poniachik T,Jaime; Mancilla A,Carla; Contreras B,Jorge; Csendes J,Attila; Smok S,Gladys; Cavada CH,Gabriel; Rojas C,Jorge; Oksenberg R,Danny; Burdiles P,Patricio; Maluenda G,Fernando; Díaz J,Juan Carlos;
Revista médica de Chile , 2002, DOI: 10.4067/S0034-98872002000700003
Abstract: background: nonalcoholic fatty liver (nafl) has been recognized as a cause of chronic liver disease. its main risk factor is obesity. aim: to describe the clinical and liver pathological findings in a group of patients who underwent surgery as obesity treatment. patients and methods: sixty eight patients with severe or morbid obesity were subjected to surgery as obesity treatment. each patient was evaluated with a complete clinical and laboratory medical assessment. a wedge of liver was excised during surgery. liver biopsies were analyzed without knowledge of clinical and laboratory findings. the presence of steatosis, inflammation (portal or lobular), fibrosis and cirrhosis were recorded in the pathological analysis. age and body mass index (bmi) were correlated with pathological data. significance was set at a p value of less than 0.05. results: ninety one percent of patients had steatosis, 45% inflammation and 47% fibrosis. one patient had cirrhosis (1,4%). there was a statistically significant association between bmi and moderate or severe steatosis (p <0.03). there was also an association between bmi and portal (p=0.017) and lobular inflammation (p=0.034). a bmi over 40 kg/m2 (morbid obesity) was significantly associated with the presence of fibrosis (p=0.032). moreover, the presence of moderate or severe steatosis was a risk factor for the development of hepatic fibrosis (p=0.026). conclusions: obesity is a major and independent risk factor for steatohepatitis and fibrosis. the degree of steatosis in the liver biopsy, is a risk factor for the development of fibrosis (rev méd chile 2002; 130: 731-6)
Neuropsychological evaluation in patients with eating disorders
Camacho Ruiz, Esteban Jaime;Escoto Ponce de León, María del Consuelo;Mancilla Díaz, Juan Manuel;
Salud mental , 2008,
Abstract: research related to neuropsychological evaluation on eating disorders (ed) has produced diverse results, being more abundant those which study attention, specifically using stroop test, both in the standard and the modified versions, using words related to food and body shape. in most of the cases, different clinical groups have not been used in the same research. studies have not used other tests which evaluate cognitive areas besides those evaluated by stroop test; and most of researchers who have measured attention with stroop test have focused on measuring latency and not interference. some studies have found deficits in attention, executive functions, and memory in patients with ed; however, other studies have not found deficits in attention. because of this evidence, the present study proposed that patients with ed would show deficits in selective attention, perseverative thinking, working memory, and executive planning, compared to a control group without ed. participants included 26 female patients with bulimia nervosa (bn) and 10 female patients with anorexia nervosa (an), matched in age and education by the control group (n = 36). all patients met eating disorders criteria, and did not have a history of neuropsychological evaluation. four neuropsychological tests were individually administered in two sessions with a counterbalanced approach: 1. wisconsin card sorting test, 2. stroop colors test (developed in the program e-prime with words related to food and body shape), 3. rey-osterrieth complex figure, and 4. tower of london test. there was a significant difference between three groups in the memory test, the execution total time and in the number of perseverative answers. in memory, the an group had the worst performance, followed by the bn group. as for the executive planning, both an and bn groups took longer to complete the test compared to the control group. finally, an and bn groups showed more perseverative answers than the control group. there wa
Neuropsychological evaluation in patients with eating disorders
Esteban Jaime Camacho Ruiz,María del Consuelo Escoto Ponce de León,Juan Manuel Mancilla Díaz
Salud mental , 2008,
Abstract: Los trabajos relacionados con la evaluación neuropsicológica de sujetos con trastornos alimentarios (TCA) han obtenido resultados diversos, y abundan más aquellos que estudian la atención, específicamente con la Prueba de Stroop, tanto en su versión estándar como en las modificadas, para lo cual emplean palabras relacionadas con la comida y la figura. En la mayoría de los casos, no se han utilizado diferentes grupos clínicos en la misma investigación. No se han utilizado tampoco otras pruebas que evalúen aspectos cognoscitivos, además de aquellos que evalúa la Prueba de Stroop; y la mayoría de las investigaciones que han medido la atención con ésta se han enfocado en medir la latencia y no la interferencia. Algunos estudios han encontrado déficits en la atención, funciones ejecutivas y en la memoria en pacientes con TCA, pero otros estudios no encontraron déficits en la atención. A la luz de estas evidencias, este trabajo hipotetiza que las pacientes con TCA presentan déficits en la atención selectiva, el pensamiento perseverativo, la memoria de trabajo y la planeación ejecutiva en comparación con un grupo de sujetos control sin TCA. El grupo de 36 pacientes de nuevo ingreso con TCA incluyó 26 mujeres con BN y 10 con AN. La muestra sin trastorno (n = 36) se emparejó por edad y nivel de estudios con la muestra de pacientes. Todas las pacientes cumplieron los criterios de TCA y no tenían historia de evaluación neuropsicológica. Se aplicaron cuatro pruebas neuropsicológicas de manera individual y contrabalanceada en dos sesiones: 1. Prueba de Ordenamiento de Tarjetas de Wisconsin, 2. Prueba de Colores de Stroop (desarrollada en el programa E-Prime, con palabras relacionadas con la comida y la figura corporal), 3. Prueba de la Figura Compleja de Rey-Osterrieth, y 4. Prueba de la Torre de Londres. Se observó una diferencia significativa entre los tres grupos en la prueba de memoria, en el tiempo total de ejecución y en el número de respuestas perseverativas. En la prueba de memoria, el grupo con AN tuvo el peor desempe o, seguido por el grupo con BN. Para la planeación ejecutiva, tanto al grupo con AN como el de BN les tomó más tiempo realizar la prueba. Finalmente, los grupos con AN y BN mostraron más respuestas perseverativas que el control. Se observó una diferencia estadísticamente significativa en el número de errores para palabras negativas relacionadas con la figura corporal. Los grupos con AN y BN cometieron más errores que el control, mientras que al grupo con BN le tomó más tiempo completar la serie de palabras negativas relacionadas con la figura
ROLE OF PEER INFLUENCE AND THIN-IDEAL INTERNALIZATION ON BODY DISSATISFACTION AND DISORDERED EATING IN MEXICAN GIRLS/ ROL DE LA INFLUENCIA DE PARES Y DE LA INTERIORIZACIóN DEL IDEAL DE DELGADEZ SOBRE LA INSATISFACCIóN CORPORAL Y ALIMENTACIóN NO SALUDABLE EN JóVENES MEXICANAS/ O PAPEL DA INFLUêNCIA DE PARES E DA INTERIORIZA O DO IDEAL DE DELGADEZA NA INSATISFA O CORPORAL E NA ALIMENTA O N O SAUDáVEL EM JOVENS MEXICANAS
Juan Manuel Mancilla-Díaz,Xochitl López-Aguilar,Karina Franco-Paredes,Georgina Alvarez-Rayón
Revista Colombiana de Psicología , 2012,
Abstract: The aim of this study was to examine the role of peer influence and thin-ideal internalization on body dissatisfaction and disordered eating. The Eating Attitudes Test, the Body Shape Questionnaire and the Questionnaire of Sociocultural Influences on the Aesthetic Body Shape Model were administered to 130 female students, with a mean age of 19.44. The results showed that thin-ideal internalization mediated the relationship between peer influence and body dissatisfaction (β=0.14, p>.05), and the relationship between peer influence and disordered eating (β=0.09, p>.05). This study supports the hypothesis that the thin-ideal internalization is an important mediator on body dissatisfaction and disordered eating in Mexican girls.
Perfectionism in Body Dissatisfaction, Sociocultural Influence of the Thinness model and Symptoms of Eating Disorders
Karina Franco Paredes,Juan Manuel Mancilla-Díaz,Rosalía Vásquez-Arévalo,Georgina álvarez Rayón
Universitas Psychologica , 2011,
Abstract: The purpose of this study was to assess if perfectionism components explained body dissatisfaction (BD), sociocultural influences of aesthetic model (SIAM) and symptoms of eating disorders (ED). The sample comprised 30 women with Bulimia Nervosa (BN), 35 women with Eating Disorder not Otherwise Specified (EDNOS) and 63 women without ED. A regression analysis showed that concern over mistakes (CM) and doubt about actions explained BD and SIAM in the BN sample; while concern over mistakes only explained SIAM in the EDNOS sample. These findings evidence that two perfectionism components contribute to vulnerability of thinness ideal and BD among women, which constitute two important risk factors for ED.
Insatisfacción corporal e influencia de los modelos estéticos en ni os y jóvenes varones mexicanos
Rosalía Vázquez Arevalo,Xóchitl López Aguilar,Georgina Leticia álvarez Rayón,Juan Mauel Mancilla Díaz
Ense?anza e Investigación en Psicología , 2006,
Abstract: El objetivo del presente estudio fue comparar en ni os y jóvenes varones la sintomatología de trastorno alimentario y de dos factores asociados: la insatisfacción corporal y la influencia del modelo estético corporal. Participaron 45 ni os y 42 jóvenes del sexo masculino, quienes fueron entrevistados y respondieron a los tests de Actitudes Alimentarias, Interiorización del Modelo Estético Corporal e Insatisfacción Corporal. La sintomatología de trastorno alimentario fue mayor en los ni os que en los jóvenes; no obstante, no se halló en ellos una asimilación considerable de los modelos estéticos corporales de delgadez, a diferencia de los jóvenes, quienes al parecer están bajo la influencia de la publicidad y del grupo de amigos.
Administración del 8-OH-DPAT en el núcleo ventromedial hipotalámico: caracterización de la conducta alimentaria
López Alonso, Verónica Elsa;Mancilla Díaz, Juan Manuel;Rito Domingo, Melissa;Jiménez Fujarte, Armando Giovanni;Díaz Urbina, Daniel;
Revista mexicana de análisis de la conducta , 2010,
Abstract: the present study evaluated the effects of 5-ht1a receptor agonist 8-oh-dpat on the behavioral satiety sequence (bss) in rats. the 8-oh-dpat was administered via central in the hypothalamic ventromedial nucleus (vmn) in rats. the experimental subjects were kept under a dietary self-selection paradigm consisting of proteins, carbohydrates and fats. food and water were available all the time. intra-vmn administration of 5-ht1a agonist was associated with the selective increase in carbohydrate intake. the bss analysis revealed that the administration of 8-oh-dpat delayed the natural development of the bss. the results lead to the conclusion that 5-ht1a receptors in the nvh involved in the modulation of food intake, is discussed the possible involvement of interactions with other neurotransmitters systems.
Imagen Corporal y Trastornos de la Conducta Alimentaria
álvarez-Rayón,Georgina; Franco-Paredes,Karina; López-Aguilar,Xochitl; Mancilla-Díaz,Juan M; Vázquez-Arévalo,Rosalia;
Revista de Salud Pública , 2009, DOI: 10.1590/S0124-00642009000400008
Abstract: objective assessing the association of age and weight with internalisation of the ideal of being thin, bodily dissatisfaction and eating disorder symptoms amongst three groups of females: teenage, young and adult women. material and methods 145 females participated, ranging in age from 12 to 46, who answered four self-reporting questionnaires aimed at measuring symptoms of anorexia nervosa, bulimia nervosa, the ideal of being thin and bodily dissatisfaction. the participants’ weight and height were also recorded for calculating their body mass index. data analysis included descriptive and inferential statistics, specifically spearman correlation and kruskal-wallis test. results being an older woman was associated with high internalisation of ideally being thin and bodily dissatisfaction; however, it was not correlated with eating disorder symptoms. comparisons between groups showed that adult females were more dissatisfied with their bodies and their attitudes towards being thin; however, their attitudes and behaviour concerning abnormal eating were just as inappropriate as that amongst teenagers. conclusions these findings show the need for research into attitudes towards eating amongst adult women because they use extreme methods for controlling weight which may result in higher health risks.
Efectos de antagonistas selectivos y no selectivos a receptores 5-HT2C sobre la estructura de la conducta alimentaria en ratas
Mancilla-Díaz, Juan Manuel;Escartín-Pérez, Rodrigo Erick;López-Alonso, Verónica Elsa;Rito-Domingo, Melissa;
Revista mexicana de análisis de la conducta , 2008,
Abstract: it is known that the 5-ht2c receptors are involved in the regulation of food intake. nevertheless, the relative role of selective and nonselective 5-ht2c receptor antagonists in the control of feeding behavior remains uncertain. in the present study, we examined the effects of serotonin (5-ht) on the feeding behavior patterns of rats pretreated with rs-102221 (5-ht2c receptor selective antagonist) or cyproheptadine (5-ht2c/2a receptor antagonist). the drugs were injected into the paraventricular hypothalamus nucleus (pvn). the animals were maintained in a self-selection feeding paradigm and provided with freely available and separate sources of protein, carbohydrate, fat, and water. the rats were kept at 21 ± 1°c on a 12 h light and 12 h dark cycle. our results indicate that more selective 5-ht2c antagonists induce a major blockade of the hypophagic effect produced by 5-ht in the pvn. both, selective and nonselective 5-ht2c receptors have shown participation in feeding behavior, mainly in the expression of satiation.
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