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Search Results: 1 - 10 of 155422 matches for " Joseph B. Rosales "
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Protein Phosphatase 1 β Paralogs Encode the Zebrafish Myosin Phosphatase Catalytic Subunit
Vaishali Jayashankar, Michael J. Nguyen, Brandon W. Carr, Dale C. Zheng, Joseph B. Rosales, Joshua B. Rosales, Douglas C. Weiser
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0075766
Abstract: Background The myosin phosphatase is a highly conserved regulator of actomyosin contractility. Zebrafish has emerged as an ideal model system to study the in vivo role of myosin phosphatase in controlling cell contractility, cell movement and epithelial biology. Most work in zebrafish has focused on the regulatory subunit of the myosin phosphatase called Mypt1. In this work, we examined the critical role of Protein Phosphatase 1, PP1, the catalytic subunit of the myosin phosphatase. Methodology/Principal Findings We observed that in zebrafish two paralogous genes encoding PP1β, called ppp1cba and ppp1cbb, are both broadly expressed during early development. Furthermore, we found that both gene products interact with Mypt1 and assemble an active myosin phosphatase complex. In addition, expression of this complex results in dephosphorylation of the myosin regulatory light chain and large scale rearrangements of the actin cytoskeleton. Morpholino knock-down of ppp1cba and ppp1cbb results in severe defects in morphogenetic cell movements during gastrulation through loss of myosin phosphatase function. Conclusions/Significance Our work demonstrates that zebrafish have two genes encoding PP1β, both of which can interact with Mypt1 and assemble an active myosin phosphatase. In addition, both genes are required for convergence and extension during gastrulation and correct dosage of the protein products is required.
Accelerated tests of coil coatings
Rosales, B. M.,Simancas, J.,Flores, S.
Revista de Metalurgia , 2003,
Abstract: Accelerated laboratory tests on 12 materials in study in the Subgroup 6 of the PATINA Network (CYTED), are discussed for different exposition periods in salt spray, SO2 and Prohesion chambers. International standards used to evaluate failures caused by the different aggressive agents of these laboratory tests are the same as those applied for outdoor expositions. The results exposed contribute to a better understanding of the mechanisms occurred in the diverse natural environments, being mentioned the main analogies and differences respect to factors affecting natural tests. They also allowed to evidence the advantages and limitations in the application of these tests during several days, as compared to the years required to attain similar failure magnitudes through outdoor tests. En este trabajo se discuten los ensayos de laboratorio acelerados, realizados sobre 12 materiales de estudio en el Subgrupo 6 de la Red PATINA (CYTED), a diferentes periodos de exposición en cámaras de niebla salina, SO2 y Prohesion. Se utilizaron las normas internacionales para evaluar los fallos causados por los diferentes agentes agresivos de estos ensayos de laboratorio, las cuales se aplican también para los ensayos de exposición a la intemperie. Los resultados expuestos contribuyen a una mejor comprensión de los mecanismos ocurridos en los diversos ambientes naturales, mencionándose las principales analogías y diferencias respecto de los factores que afectan los ensayos naturales. También permitieron evidenciar las ventajas y limitaciones en la aplicación de estos ensayos durante varios días, en comparación con los a os requeridos para alcanzar magnitudes de fallos similares por medio de ensayos a intemperie.
A Centralized Energy Coordinator Reliant on BESS and DER-PV Operation  [PDF]
Joseph M. Lavalliere, Elham B. Makram
Journal of Power and Energy Engineering (JPEE) , 2016, DOI: 10.4236/jpee.2016.48005
Abstract: Many existing battery energy storage system (BESS) control schemes focus on mitigating negative impacts resulting from the operation of distributed energy resources-photovoltaic facilities (DER-PV). These include out-of-firm conditions from reverse power flow or extreme variability in the service voltage. Existing control strategies fail to consider how BESS control schemes need to operate in a consecutive day-to-day basis in order for them to be implemented in the field. In this paper, a novel energy management algorithm capable of dispatching a BESS unit upstream of a multi-megawatt DER-PV is introduced. This algorithm referenced as the Master Energy Coordinator (MEC), accepts forecasted DER-PV generation and individual feeder load to create daily charge and discharge rate schedules. Logic is integrated to the cyclic discharging event to sync with the forecasted peak load, even when it will occur during the morning of the next day. To verify the MEC operation, Quasi-Static Time Series (QSTS) simulations are conducted on a 12.47 kV distribution feeder model utilizing historical head-of-feeder and DER-PV analog DSCADA measurements.
Effects of soothing music on labor pain among Filipino mothers
Leodoro J. Labrague,Rheajane A. Rosales,Gilbey L. Rosales,Gerald B. Fiel
Clinical Nursing Studies , 2013,
Abstract: Background: Labor pain is the most undesirable and unpleasant aspect of labor experience during childbirth. In the Philippines, especially in government hospitals, they seldom receive pharmacologic and non-pharmacologic management to reduce pain. Thus, the purpose of this study was to identify the effect of soothing music on the perception of pain during the latent phase of labor among laboring women in a government hospital.Methodology: A quasi-experimental design with random assignment was utilized in this investigation. Fifty subjects were assigned into either music (n=25) or non-music group (n=25). Participants’ levels of pain were measured utilizing the visual analogue scale (VAS) for pain and the behavioral rating scale (BRS) for pain at two time period. The non-music group was provided with the usual standard routine of care while the music group was provided with the usual standard routine of care and was exposed music therapy for 30 minutes. Results: Findings revealed that those in the music group had statistically significant reduction in reported pain levels compared to those in the non-music group [VAS (t=7.317, p<0.05) and BRS (t=8.128, p<0.050)]. Conclusion: The finding provides promising result that soothing music during the latent phase of labor provides pain reduction and can be used as part their routine when providing care for women during this stage.
Investigation of Fecraly Coating on Corrosion Behaviour of Mild Steel
Leonardo Journal of Sciences , 2009,
Abstract: Steel has found wide application in hot rolling equipments in the steel industry and the oil rig structures in sea water. These equipments are frequently subjected to corrosive and temperature condition which causes severe damage to them, hence the need to develop steel suitable to withstand these conditions in terms of surface treatment. This research work investigates the effect of FeCrAlY coating on mild steel under high temperature and aggressive environment. Iron based coatings are used due to low cost among other properties such as good corrosion resistance, ease of machining and high ductility when compared to hard metals.Thermal spraying of the specimens was carried out using high velocity oxygen fuel (HVOF). Corrosion test was carried out on both coated and uncoated samples. All samples were subjected to the same high temperature treatment for oxidation test.
The Culture and Development Index (CDI): Measuring Values and Attitudes Associated With Development In Selected Asian and Latin American Countries
Joseph I. B. Gonzales
Terengganu International Management and Business Journal , 2011,
Abstract: Analyzing data gathered in five waves in the period 1981–2005 for up to 97 societies (most of which are independent countries), the World Values Survey Organization (WVSO) identified two orthogonal factors, Traditional/Secular-Rational Values, and Survival/Self-Expression Values, that account for up to 70 percent of cross-cultural variation worldwide. However, one weakness of the two-factor construct is that it overlooks regional or local patterns in values and attitudes that may be vitally related to development. Alternatively, the Culture and Development Index (CDI) and the closely related Culture and Corruption Index (CCI) are constructed for selected South and Southeast Asian, Latin American, and East Asian countries to account for cross-cultural variation in terms of a different set of orthogonal factors, some of which are strongly associated with leading measures of development and of corruption. Both CDI and CCI reveal patterns of value and attitudinal change relevant to promoting development and to mitigating corruption.
Occupation Related Accidents in Selected Garment Industries in Bangalore City
Calvin S,Joseph B
Indian Journal of Community Medicine , 2006,
Facial myokymia as a presenting symptom of vestibular schwannoma.
Joseph B,Rajshekhar V
Neurology India , 2002,
Abstract: Facial myokymia is a rare presenting feature of a vestibular schwannoma. We present a 48 year old woman with a large right vestibular schwannoma, who presented with facial myokymia. It is postulated that facial myokymia might be due to a defect in the motor axons of the 7th nerve or due to brain stem compression by the tumor.
Current Challenges in Spina Bifida Care
David B. Joseph
The Scientific World Journal , 2007, DOI: 10.1100/tsw.2007.263
Piecewise Linear Phase Transitions
Joseph B. Keller
Physics , 2007,
Abstract: It is shown how simple assumptions lead to piecewise linear behavior, which is observed in certain phase transitions.
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