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Search Results: 1 - 10 of 13240 matches for " Josabete SB;Martins "
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Aduba??o organica, mineral e organomineral e sua influencia no crescimento da helic?nia em Garanhuns-PE
Carvalho, Josabete SB;Martins, Jéssyca DL;Ulisses, Cláudia;Silva, Wilkilane L;
Horticultura Brasileira , 2012, DOI: 10.1590/S0102-05362012000400003
Abstract: heliconia stands out for its beauty and variety of shapes and colors and this plant is among the most traded tropical flowers in the world. we evaluated the growth and development of heliconia psittacorum x h. spathocircinata cv. golden torch, submitted to organic and mineral fertilization. the experiment was carried out in field, in a completely randomized design. the treatments consisted of four doses of fertilizer (control (t1) local soil; cattle manure (t2); mineral fertilizer npk (t3) and cattle manure + npk (t4)), in ten replications. we evaluated plant height, number of shoots, flowering time, number, size and weight of inflorescences. the combination of mineral fertilizer (npk) and organic (manure) (organomineral) significantly affected plant height resulting in an increase of over 23% when compared with the control 330 days after planting date. after six months of cultivation, all plants exhibited a very homogeneous and vigorous growth without visual symptoms of nutrient deficiency, showing that chemical fertilization associated with cattle manure (organomineral) is highly recommended for growing heliconia cv. golden torch. this cultivar can be well adapted to the conditions of garanhuns, pernambuco state, brazil.
Triple bothropic envenomation in horses caused by a single snake
Chiacchio, SB;Martins, GTB;Amorim, RM;Gon?alves, RC;Barraviera, B;Ferreira Junior, RS;
Journal of Venomous Animals and Toxins including Tropical Diseases , 2011, DOI: 10.1590/S1678-91992011000100016
Abstract: in the present study, snakebites caused by a single bothrops pauloensis simultaneously affecting three male adult horses are described. whereas the first two affected horses were six years old, the third was 16 years old; they weighed respectively 555, 550 and 500 kg. all horses presented swollen muzzles. the first animal received an initial antivenom dose of 19 vials and adjuvant medication, it was also subjected to tracheostomy due to the progression of acute respiratory failure. the second and third horses respectively received 15 vials of antivenom each, in addition to adjuvant medication. due to continuous changes in blood coagulation observed during hospitalization, the first and the second horses received five more vials of antivenom, respectively, in the second and third days of treatment. the first animal was discharged on 15th day and the other on the 8th day of hospitalization. several factors including the main actions of bothrops venom (coagulation, proteolytic and vasculotoxic activities), the importance of early diagnosis based on clinical history and clinical examination suggesting the diagnosis of bothrops snakebite, the adequate doses of antivenom, and finally the immediate tracheostomy are herein discussed. the tracheostomy, required to save the life of the first horse, should only occur after the administration of antivenom and control measures for changes in blood coagulation.
Modulatory role of eosinophils in allergic inflammation: new evidence for a rather outdated concept
Bandeira-Melo, Christianne;Cordeiro, Renato SB;Silva, Patrícia MR;Martins, Marco A;
Memórias do Instituto Oswaldo Cruz , 1997, DOI: 10.1590/S0074-02761997000800007
Abstract: the eosinophilic response has been identified as a key alteration in the pathogenesis of asthma and other allergic diseases. a close-correlation between disease severity and eosinophilia, and the eosinophil ability to provide toxic and pro-inflammatory agents are the major elements supporting the interpretation that there is indeed a causal relationship between these phenomena. nevertheless, controversy still persists since some studies have clearly demonstrated that eosinophil infiltration is not necessarily accompanied by tissue damage or hyperresponsiveness. in addition, there are some examples in the literature in which such alterations are not modified following abrogation of eosinophil influx. in this review it will be argued, based on a model of ige-dependent pleurisy, that eosinophil infiltration can be associated with down-regulation of allergic inflammatory response. the potential mechanism by which eosinophils could be acting as a immunomodulatory cells in this particular system will also be assessed.
Modulatory role of eosinophils in allergic inflammation: new evidence for a rather outdated concept
Bandeira-Melo Christianne,Cordeiro Renato SB,Silva Patrícia MR,Martins Marco A
Memórias do Instituto Oswaldo Cruz , 1997,
Abstract: The eosinophilic response has been identified as a key alteration in the pathogenesis of asthma and other allergic diseases. A close-correlation between disease severity and eosinophilia, and the eosinophil ability to provide toxic and pro-inflammatory agents are the major elements supporting the interpretation that there is indeed a causal relationship between these phenomena. Nevertheless, controversy still persists since some studies have clearly demonstrated that eosinophil infiltration is not necessarily accompanied by tissue damage or hyperresponsiveness. In addition, there are some examples in the literature in which such alterations are not modified following abrogation of eosinophil influx. In this review it will be argued, based on a model of IgE-dependent pleurisy, that eosinophil infiltration can be associated with down-regulation of allergic inflammatory response. The potential mechanism by which eosinophils could be acting as a immunomodulatory cells in this particular system will also be assessed.
Crescimento de calos embriogênicos de milho submetidos ao estresse salino
Bezerra, Josabete Salgueiro;Willadino, Lília;Camara, Terezinha Rangel;
Scientia Agricola , 2001, DOI: 10.1590/S0103-90162001000200007
Abstract: soil salinity is a very important problem in irrigated areas of the brazilian semi-arid area, where maize is a subsistence crop. to study the effect of nacl concentrations in embryogenic calli of jatin? c3 an?o, an important maize cultivar of the northest of brazil, calli were induced using immature embryos aseptically removed from the seeds and grown on n6 medium supplemented with 2 mg l-1 of 2,4-d. to study the effect of salinity in vitro, embryogenic calli were subjected to different concentrations of sodium chloride (0; 50; 100; 150 and 200 mmol l-1 of nacl), in three replicates, during 60 days. calli subjected up to100 mmol l-1 nacl showed proline concentration 37% higher than callus treated with 50 mmol l-1 nacl. this result suggests a positive effect of proline accumulation at salt stress conditions. however, at the highest concentration tested (150-200 mmol l-1 nacl) as lower growth and also a lower proline accumulation was observed, probably due to an increase of the non embryogenic fraction of calli.
Crescimento de calos embriogênicos de milho submetidos ao estresse salino
Bezerra Josabete Salgueiro,Willadino Lília,Camara Terezinha Rangel
Scientia Agricola , 2001,
Abstract: A salinidade do solo é um problema muito importante em áreas irrigadas do semi-árido brasileiro, onde o milho é uma cultura de subsistência. Este trabalho teve como objetivo estudar o efeito de concentra es de NaCl sobre calos embriogênicos, da cultivar Jatin C3 An o, uma importante cultivar de milho no Nordeste do Brasil. A indu o dos calos foi feita a partir de embri es imaturos assepticamente retirados das sementes e inoculados em meio de cultura N6 suplementado com 2 mg L-1 de 2,4-D. Os calos embriogênicos foram submetidos a diferentes concentra es de cloreto de sódio (0; 50; 100; 150 e 200 mmol L-1 de NaCl), com três repeti es durante 60 dias. Os calos submetidos a 100 mmol L-1 de NaCl apresentaram aumento no conteúdo de prolina na ordem de 37% quando comparado com o nível de 50 mmol L-1 de NaCl, sugerindo um efeito positivo da acumula o deste aminoácido em resposta ao estresse salino. Por outro lado, em elevadas concentra es salinas (150 e 200 mmol L-1) observou-se decréscimo no crescimento dos calos, bem como redu o nos teores de prolina, provavelmente em fun o de um aumento da fra o n o embriogênica dos calos.
Mast cell changes in experimental diabetes: focus on attenuation of allergic events
Carvalho, Vinicius F;Barreto, Emiliano O;Cordeiro, Renato SB;Lagente, Vincent;Martins, Marco A;e Silva, Patrícia MR;
Memórias do Instituto Oswaldo Cruz , 2005, DOI: 10.1590/S0074-02762005000900021
Abstract: the prevalence of atopic diseases and diabetes is increasing worldwide though the concurrence of these pathologies in individual patients is found less frequent than it would be predicted. moreover, co-existence of diabetes and allergy is generally marked by attenuation of their respective symptoms, and effective treatment of one disease exacerbates the other. this review gives an update of the state-of-the-art concerning the intercurrence of allergy and diabetes, particularly focusing on the consequences to the allergen-evoked vascular and cellular changes. it is proposed that the reduction in mast cell numbers and reactivity may be a pivotal mechanism behind the mutual exclusion phenomenon.
Local anaesthetic medication for the treatment of asthma
Siqueira, Rodrigo A;Costa, Jorge CS;Cordeiro, Renato SB;Serra, Magda F;e Silva, Patrícia MR;Martins, Marco A;
Memórias do Instituto Oswaldo Cruz , 2005, DOI: 10.1590/S0074-02762005000900027
Abstract: it is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. the local anaesthetic lidocaine has recently received increased attention as an alternative form of treatment for asthmatic patients. this paper reviews the major findings on the topic and summarizes the putative mechanisms underlying the airway effects of local anaesthetic agents. we think that lidocaine extends the spectrum of options in asthma therapy, probably by counteracting both spasmogenic and inflammatory stimuli in the bronchial airways. the possibility of development of new anti-asthma compounds based on the synthesis of lidocaine derivatives is also on the horizon.
Antigen-induced pleural eosinophilia is suppressed in diabetic rats: role of corticosteroid hormones
Diaz, Bruno L;Serra, Magda F;Barreto, Emiliano O;Cordeiro, Renato SB;Martins, Marco A;Silva, Patricia MR e;
Memórias do Instituto Oswaldo Cruz , 1997, DOI: 10.1590/S0074-02761997000800031
Abstract: previous studies have evidenced for the existence of interactive regulatory mechanisms between insulin and steroid hormones in different systems. in this study, we have investigated whether endogenous corticosteroids could be implicated in the hyporeactivity to antigen challenge observed in sensitized diabetic rats. alloxinated rats showed a long-lasting increase in the blood glucose levels and a reduction in the number of pleural mast cells at 48 and 72 hr, but not at 24 hr after alloxan administration. in parallel, they also showed a significant elevation in the plasma levels of corticosterone together with an increase in the adrenal/body weight ratio. antigen-evoked eosinophil accumulation appeared significantly reduced in rats pretreated with dexamethasone as well as in those rendered diabetic 72 hr after alloxan. in the same way, naive animals treated with dexamethasone also responded with a significant decrease in the number of pleural mast cells. interestingly, when sensitized diabetic rats were pretreated with the steroid antagonist ru 38486 a reversion of the reduction in the allergen-induced eosinophil accumulation was noted. we conclude that the down-regulation of the allergic inflammatory response in diabetic rats is close-related to reduction in mast cell numbers and over expression of endogenous corticosteroids.
Effect of selective phosphodiesterase inhibitors on the rat eosinophil chemotactic response in vitro
Alves, Alessandra C;Pires, Ana Lucia A;Lagente, Vincent;Cordeiro, Renato SB;Martins, Marco A;Silva, Patricia MR e;
Memórias do Instituto Oswaldo Cruz , 1997, DOI: 10.1590/S0074-02761997000800027
Abstract: in the present study, we have performed a comparative analysis of the effect of selective inhibitors of phosphodiesterase (pde) type iii, iv and v on eosinophil chemotaxis triggered by platelet activating factor (paf) and leukotriene b4 (ltb4) in vitro. the effect of the analogues n6-2'-o-dibutyryladenosine 3':5' cyclic monophosphate (bt2 cyclic amp) and n2-2'-o- dibutyrylguanosine 3':5' cyclic monophosphate (bt2 cyclic gmp) has also been determined. the eosinophils were obtained from the peritoneal cavity of naive wistar rats and purified in discontinuous percoll gradients to 85-95% purity. we observed that pre-incubation of eosinophils with the pde type iv inhibitor rolipram suppressed the chemotactic response triggered by paf and ltb4, in association with an increase in the intracellular levels of cyclic amp. in contrast, neither zaprinast (type v inhibitor) nor type iii inhibitors milrinone and sk&f 94836 affected the eosinophil migration. only at the highest concentration tested did the analogue bt2 cyclic amp suppress the eosinophil chemotaxis, under conditions where bt2 cyclic gmp was ineffective. we have concluded that inhibition of pde iv, but not pde iii or v, was able to block the eosinophil chemotaxis in vitro, suggesting that the suppressive activity of selective pde iv inhibitors on tissue eosinophil accumulation may, at least, be partially dependent on their ability to directly inhibit the eosinophil migration.
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