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Search Results: 1 - 10 of 646713 matches for " José Jesús Guillén-Pérez "
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Mercury in Canned Tuna in Spain. Is Light Tuna Really Light?  [PDF]
Montserrat González-Estecha, María José Martínez-García, Manuel Fuentes-Ferrer, Andrés Bodas-Pinedo, Alfonso Calle-Pascual, José María Ordó?ez-Iriarte, Cristina Fernández-Pérez, Nieves Martell-Claros, Miguel ángel Rubio-Herrera, Emilia Gómez-Hoyos, José Jesús Guillén-Pérez
Food and Nutrition Sciences (FNS) , 2013, DOI: 10.4236/fns.2013.47A007

In Spain, certain population-based studies have shown high blood mercury (Hg) levels due to the high consumption of fish. Some studies have stated that one of the most consumed fish in Spain is canned tuna. Different Spanish organisms consider that it is safe to consume canned tuna as it supposedly has a low mercury content, particularly in so-called light tuna. However, in Spain light tuna is mainly yellowfin and bigeye tuna, while in other countries it is mainly skipjack tuna. This study analyzed 36 cans of the most popular brands in Spain and examined the influence of the type of tuna, packaging medium (olive oil, sunflower seed oil, water or marinade), different brands, prices and expiration dates. Mercury concentrations (mg/kg) were measured by atomic absorption spectrometry and thermal decomposition amalgamation. The medians observed were (mg/kg): light tuna: 0.314; IQR: 0.205 - 0.594, white tuna: 0.338; IQR: 0.276 - 0.558, skipjack: 0.311; IQR: 0.299 - 0.322, frigate tuna: 0.219; IQR 0.182 - 0.257 and mackerel: 0.042; IQR 0.029 - 0.074. We found statistically significant differences between white tuna, light tuna and mackerel (p = 0.004); light tuna and mackerel (p = 0.002) and white tuna and mackerel (p = 0.006). However, we found no differences between white tuna and light tuna, or among packaging medium, brands, prices or expiration dates. The limit of 0.500 mg/kg of mercury in canned tuna was exceeded by the following percentages of the cans: 33.3% of light tuna, 16.7% of white tuna, and 0% of Skipjack, frigate tuna and mackerel. The mercury content of the cans of Spanish light tuna that were analyzed was variable and high. The results of this study indicate that stricter regulation of Hg in canned tuna is necessary. Until then, it is safer to recommend that vulnerable populations such as children and pregnant women consume canned mackerel, which has a markedly lower mercury content.

Factores psicosociales relacionados con el consumo doméstico de agua en una región semidesértica
Arreguín-Moreno,Rocío Haydee; Román-Pérez,Rosario; Laborín-álvarez,Jesús Francisco; Moreno,José Luis; Valdez,Elba Abril; Valenzuela,Blanca;
Salud Pública de México , 2009, DOI: 10.1590/S0036-36342009000400009
Abstract: objective: to analyze psychosocial factors related with domestic water consumption in hermosillo, sonora, a semidesert region in northwestern mexico. an intentionally selected sample of 198 people (79 men and 119 women) from a higher education institution was used to evaluate the theories of rational action and self-efficacy. material and methods: a scale with the psychosocial factors to be analyzed and likert-type items was applied. results: the age mean was 35 years old. a positive moderate association was found between the diverse factors, particularly between intention-norm, beliefs-intention, beliefs-self-efficacy, attitude-intention, attitude-self-efficacy, and self-efficacy-intention. conclusions: despite the fact that the sample characteristics do not allow results to be generalized, the study shows the usefulness of the psychosocial factors that were analyzed and suggests the possibility of including them in educational programs that promote careful water use at home.
Oleic Acid and Octanoic Acid Sensing Capacity in Rainbow Trout Oncorhynchus mykiss Is Direct in Hypothalamus and Brockmann Bodies
Marta Librán-Pérez, Marcos A. López-Pati?o, Jesús M. Míguez, José L. Soengas
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0059507
Abstract: In a previous study, we provided evidence for the presence in hypothalamus and Brockmann bodies (BB) of rainbow trout Oncorhynchus mykiss of sensing systems responding to changes in levels of oleic acid (long-chain fatty acid, LCFA) or octanoic acid (medium-chain fatty acid, MCFA). Since those effects could be attributed to an indirect effect, in the present study, we evaluated in vitro if hypothalamus and BB respond to changes in FA in a way similar to that observed in vivo. In a first set of experiments, we evaluated in hypothalamus and BB exposed to increased oleic acic or octanoic acid concentrations changes in parameters related to FA metabolism, FA transport, nuclear receptors and transcription factors, reactive oxygen species (ROS) effectors, components of the KATP channel, and (in hypothalamus) neuropeptides related to food intake. In a second set of experiments, we evaluated in hypothalamus the response of those parameters to oleic acid or octanoic acid in the presence of inhibitors of fatty acid sensing components. The responses observed in vitro in hypothalamus are comparable to those previously observed in vivo and specific inhibitors counteracted in many cases the effects of FA. These results support the capacity of rainbow trout hypothalamus to directly sense changes in MCFA or LCFA levels. In BB increased concentrations of oleic acid or octanoic acid induced changes that in general were comparable to those observed in hypothalamus supporting direct FA sensing in this tissue. However, those changes were not coincident with those observed in vivo allowing us to suggest that the FA sensing capacity of BB previously characterized in vivo is influenced by other neuroendocrine systems.
Cierre transcatéter del conducto arterioso permeable con coils de liberación controlada: Resultados inmediatos y seguimiento a mediano plazo
Parra-Bravo, José Rafael;Acosta-Valdez, José Luis;Girón-Vargas, Ana Luisa;Beirana-Palencia, Luisa Gracia;Rodríguez-Hernández, Lydia;Estrada-Loza, María de Jesús;Galicia-Galicia, José Alfredo;Lazo-Cárdenas, César;Santillán-Pérez, Leticia;
Archivos de cardiología de México , 2005,
Abstract: objective: to determine the success rate and safety of percutaneous closure of patent ductus arteriosus (pda) with a detachable coil. methods: forty-one children with small-to moderate-size pda (maximum diameter < 4 mm) underwent percutaneous coil occlusion. the results were assessed by angiography and echocardiography the mean age was 2.0 ± 1.3 years (range 0.6 to 5.6 years); mean weight was 10.0 ± 3.4 kg (range 4.5 to 18.0 kg). the mean minimum diameter of the pda was 1.7 ± 0.6 mm (range, 0.5 to 4.0 mm). results: the occlusion device was inserted in 39 of 41 patients (95%). the mean coil/pda ratio was 3.41 ±1.1. we observed angiographic cessation of blood flow through the pda after coil insertion in 18 patients; 18 patients had residual shunt, 3 mild shunt and 2 moderate shunt. no complications were observed during the procedure. thirty-five patients showed absence of blood flow through pda 24 hours after coil occlusion by echocar-diography the other four patients with residual shunt showed flow cessation after 2 months in two patients and after 6 months in the other two. failure of coil insertion in two patients was due to detachment of the pulmonary edge of the coil, which was subsequently removed in one, and due to coil migration in the other, both patients underwent surgical pda closure. mean follow-up at 29.5 ± 16.5 months showed no residual blood flow through the occluded pda, except for one patient. conclusion: our results, as many others, suggest that pda coil occlusion is a safe, effective, and cheap procedure. pda coil occlusion should be the elective method for pda closure in patients older than 6 months of age with small-to moderate size pda(< 4 mm). the procedure in newborn infants and patients with larger pda must be made with a different type of occlusive device.
La profesión dental en Espa?a. Análisis de la situación actual a partir de las ofertas formativas de educación continuada: Estudio piloto
Martín-Pérez,Ma Jesús; Mallo-Pérez,Luciano;
RCOE , 2003, DOI: 10.4321/S1138-123X2003000600002
Abstract: objective: to understand the current trends in the dental profession in spain, from the analysis of the offers for postgraduate studies. material and method: the analysis was performed on a total of 529 offers appearing on 3 consecutive issues of the journals gaceta dental (3 months) and maxillaris (3 months), between september 2002 and february 2003. their subject, duration and organizer were considered. in addition, the annual reports of the general council of the professional associations of odontology and stomatology of spain corresponding to the years 2002 and 2003 (203 entries) were analyzed. results: courses on implantology were the most frequently offered (27.5%), followed by those on orthodontics (17.6%) and periodontics (6.1%). most of the offers (68.5%) were organized by private initiatives. 43.3% were short courses, 27.8% were of intermediate duration and 27.8% of the courses offered more than 60 teachy hours. from the courses offered by the official professional associations of odontology and stomatology, 70.5% are technically or technologically oriented.
Motor Effects of 1,3-Disubstituted 8-Styrylxanthines as A1 and A2 Adenosine-Receptor Antagonists in Rats  [PDF]
Ilhuicamina Daniel Limón-Pérez de León, María del Carmen Parra-Cid, Alejandro Mu?oz-Zurita, Saúl Alejandro Merino-Contreras, Sara Montiel-Smith, Socorro Meza-Reyes, Gerardo Ramírez-Mejía, Jesús Sandoval-Ramírez
Pharmacology & Pharmacy (PP) , 2013, DOI: 10.4236/pp.2013.43044

A series of 1,3-substituted 8-styrylxanthines (11a-d) was synthesized, under chemo- and regioselective conditions, in a good overall yield. The compounds showed affinity towards both A1 and A2A-adenosine receptors by radioligand binding by means of in vitro assays. The (E)-3-ethyl-1-propyl-8-styrylxanthine (11a) showed the greatest affinity towards the A2A receptor, whereas (E)-3-pentyl-1-propyl-8-styrylxanthine (11d) showed the greatest affinity for the A1 receptor. When the 8-styrylxanthines 11a (A15Et) and 11c (A15Bu) were administrated in rats, which were previously injured with 6-hydroxydopamine at the substantia nigra pars compacta (SNc), the turning behavior decreased 50%. Based on these results we propose to A15Et as a potential compound to treat some symptoms of Parkinson’s disease.

Efectos a corto plazo de la contaminación atmosférica sobre la mortalidad: resultados del proyecto EMECAM en Cartagena, 1992-96
Guillén Pérez José Jesús,Cirera Suárez Lluís,García-Marcos álvarez Luis,Jiménez Torres Enrique
Revista Espa?ola de Salud Pública , 1999,
Abstract: FUNDAMENTO: Los problemas de contaminación atmosférica se han venido percibiendo en la ciudad de Cartagena desde la década de los setenta, con episodios puntuales de altos niveles de SO2 y partículas. Nos proponemos evaluar, utilizando la metodología del proyecto EMECAM, los efectos agudos de la contaminación atmosférica por SO2 y partículas sobre la mortalidad diaria en la ciudad de Cartagena de 1992 a 1996. MéTODOS: se relacionan las defunciones diarias por todas las causas excepto las externas, en población general y en la de 70 y más a os, por causas cardiovasculares y por causas respiratorias, con la contaminación atmosférica por dióxido de azufre y partículas, en el período1992-1996, utilizando modelos de Poisson autorregresiva que controlan por estacionalidad, meteorología, calendario, gripe, eventos especiales y retardos. RESULTADOS: En el periodo en estudio se ha producido una disminución de la contaminación por SO2, con respecto a a os anteriores, lo que no ha sido evidente para la contaminación por partículas. Los análisis muestran asociaciones significativas en las defunciones totales sin accidentes en mayores de 69 a os y el valor promedio de partículas, estas son las defunciones cardiovasculares del mes de mayo a octubre. En el semestre frío, encontramos asociación estadísticamente significativa positiva en el valor máximo horario diario de las partículas y las muertes por enfermedades cardiocirculatorias y respiratorias. Sin embargo no hay consistencia en las asociaciones al evaluar la fiabilidad de los modelos.
Efectos a corto plazo de la contaminación atmosférica sobre la mortalidad: resultados del proyecto EMECAM en Cartagena, 1992-96
Guillén Pérez,José Jesús; Cirera Suárez,Lluís; García-Marcos álvarez,Luis; Jiménez Torres,Enrique; Barber Vallès,Xavier; Martínez García,María José; Moreno Grau,Stella;
Revista Espa?ola de Salud Pública , 1999, DOI: 10.1590/S1135-57271999000200011
Abstract: purpose: the problems of air pollution became noticeable in cartagena in the seventies, high so2 and particle levels having been reached from time to time. our aim is to assess, using the emecam methodology, the acute impact of so2 and particle air pollution on the daily mortality of the city of cartagena in the 1992-1996 period. methods: a daily listing is provided of the total number of non-accidental deaths within the population as a whole and for those over age 70, the cardiovascular and the respiratory deaths due to the sulfur dioxide and particle air pollution for the 1992-1996 period using autoregressive poisson models which control seasonality, weather, time of year, flu, special events, and time lags. results: in the period under study, there has been a drop in the so2 air pollution as compared to previous years, which was not as marked for the particles. the analyses reveal significant relationships in the total non-accidental deaths in those over age 69, with the average particle count and those particles with cardiovascular deaths for the months of may to october. in the six-month period of the year when the weather is cold, we found a positive statistically significant relationship to exist in the maximum daily hourly value of the particles and the deaths due to cardiocirculatory and respiratory diseases. however, there is no consistency in the between on assessing the reliability of the models.
El proyecto EMECAM: discusión de los resultados en las ciudades participantes
Ballester Díez,Ferran; Sáez Zafra,Marc; Pérez-Hoyos,Santiago; Daponte Codina,Antonio; Bellido Blasco,Juan; Ca?ada Martínez,álvaro; Abad Díez,José Ma; Pérez Boíllos,Ma José; Alonso Fustel,Ma Eva; Taracido Trunk,Margarita; Aguinaga Ontoso,Inés; Jesús Guillén Pérez,José; Ordó?ez Iriarte,José Ma; Saurina Canals,Carme; Tenías Burillo,José Ma;
Revista Espa?ola de Salud Pública , 1999, DOI: 10.1590/S1135-57271999000200021
Abstract: this article draws a comparison and provides a discussion of the findings resulting from the local analyses of the 14 cities participating in the emecam project. an analysis is made of the time series related to mortality, pollutants (particles in suspension, so2, no2, o3 and co), temperature and other factors taken from records of public institutions. by using poisson autoregressive regression, an estimate has been made of the short-term relationship between the number of deaths and the air pollution indicators in each one of the following cities: barcelona, metropolitan area of bilbao, cartagena, castellón, gijón, huelva, madrid, pamplona, seville, oviedo, valencia, vigo, vitoria and saragossa. the findings reveal the air pollution figures in our country to be similar to those of other european cities. the levels of the different pollutants point toward road traffic as being the main source of most of this pollution. a relationship has been found between the mortality and different pollutants in most cities, although the results are not homogeneous among the cities and show variability in the different causes under study. in some cities, especially in those having smaller populations, there have been no findings providing any evidence of a relationship, or the findings themseves are not highly consistent. the meta-analysis will provide estimates for all of the cities as a whole and will allow the possibility of making a more clear-cut assessment of the time lag impact of air pollution on the mortality. worthy of special mention is the participation in this project of public health officiers as actively-involved researchers.
Nation-Wide, Web-Based, Geographic Information System for the Integrated Surveillance and Control of Dengue Fever in Mexico
Juan Eugenio Hernández-ávila, Mario-Henry Rodríguez, René Santos-Luna, Veronica Sánchez-Casta?eda, Susana Román-Pérez, Víctor Hugo Ríos-Salgado, Jesús Alberto Salas-Sarmiento
PLOS ONE , 2013, DOI: 10.1371/journal.pone.0070231
Abstract: Dengue fever incidence and its geographical distribution are increasing throughout the world. Quality and timely information is essential for its prevention and control. A web based, geographically enabled, dengue integral surveillance system (Dengue-GIS) was developed for the nation-wide collection, integration, analysis and reporting of geo-referenced epidemiologic, entomologic, and control interventions data. Consensus in the design and practical operation of the system was a key factor for its acceptance. Working with information systems already implemented as a starting point facilitated its acceptance by officials and operative personnel. Dengue-GIS provides the geographical detail needed to plan, asses and evaluate the impact of control activities. The system is beginning to be adopted as a knowledge base by vector control programs. It is used to generate evidence on impact and cost-effectiveness of control activities, promoting the use of information for decision making at all levels of the vector control program. Dengue-GIS has also been used as a hypothesis generator for the academic community. This GIS-based model system for dengue surveillance and the experience gathered during its development and implementation could be useful in other dengue endemic countries and extended to other infectious or chronic diseases.
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