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Search Results: 1 - 10 of 84502 matches for " José Ant?nio;Machado "
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A crise financeira e económica internacional
Vítor Bento,José Ferreira Machado,António Nogueira Leite
Rela??es Internacionais (R:I) , 2009,
Abstract:
Analysis and Visualization of Seismic Data Using Mutual Information
José A. Tenreiro Machado,António M. Lopes
Entropy , 2013, DOI: 10.3390/e15093892
Abstract: Seismic data is difficult to analyze and classical mathematical tools reveal strong limitations in exposing hidden relationships between earthquakes. In this paper, we study earthquake phenomena in the perspective of complex systems. Global seismic data, covering the period from 1962 up to 2011 is analyzed. The events, characterized by their magnitude, geographic location and time of occurrence, are divided into groups, either according to the Flinn-Engdahl (F-E) seismic regions of Earth or using a rectangular grid based in latitude and longitude coordinates. Two methods of analysis are considered and compared in this study. In a first method, the distributions of magnitudes are approximated by Gutenberg-Richter (G-R) distributions and the parameters used to reveal the relationships among regions. In the second method, the mutual information is calculated and adopted as a measure of similarity between regions. In both cases, using clustering analysis, visualization maps are generated, providing an intuitive and useful representation of the complex relationships that are present among seismic data. Such relationships might not be perceived on classical geographic maps. Therefore, the generated charts are a valid alternative to other visualization tools, for understanding the global behavior of earthquakes.
ANALYSIS OF DRAFTING EFFECTS IN SWIMMING USING COMPUTATIONAL FLUID DYNAMICS
António José Silva,Abel Rouboa,António Moreira,Victor Machado Reis
Journal of Sports Science and Medicine , 2008,
Abstract: The purpose of this study was to determine the effect of drafting distance on the drag coefficient in swimming. A k-epsilon turbulent model was implemented in the commercial code Fluent and applied to the fluid flow around two swimmers in a drafting situation. Numerical simulations were conducted for various distances between swimmers (0.5-8.0 m) and swimming velocities (1.6-2.0 m.s-1). Drag coefficient (Cd) was computed for each one of the distances and velocities. We found that the drag coefficient of the leading swimmer decreased as the flow velocity increased. The relative drag coefficient of the back swimmer was lower (about 56% of the leading swimmer) for the smallest inter-swimmer distance (0.5 m). This value increased progressively until the distance between swimmers reached 6.0 m, where the relative drag coefficient of the back swimmer was about 84% of the leading swimmer. The results indicated that the Cd of the back swimmer was equal to that of the leading swimmer at distances ranging from 6.45 to 8. 90 m. We conclude that these distances allow the swimmers to be in the same hydrodynamic conditions during training and competitions.
Total IgE detection in paired cerebrospinal fluid and serum samples from patients with neurocysticercosis
BUENO, Ednéia Casagranda;VAZ, Adelaide José;MACHADO, Luís dos Ramos;LIVRAMENTO, José Antnio;
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000, DOI: 10.1590/S0036-46652000000200002
Abstract: neurocysticercosis (nc), the presence of taenia solium metacestodes in tissues, is the most frequent and severe parasitic infection of the central nervous system. we investigated the presence of total ige by an automated chemiluminescence assay in 53 paired cerebrospinal fluid (csf) and serum samples from patients with nc (p) and in 40 csf samples from individuals with other neurological disorders as the control group (c). total ige concentration ranged from 1.2 to 6.6 iu/ml (mean = 1.4 iu/ml, standard deviation-sd = 1.1 iu/ml) in 28.3% of csf samples from the p group, a value significantly higher than for the c group (£1.0 iu/ml). the serum samples from the p group showed concentrations ranging from 1.0 to 2330.0 iu/ml (mean = 224.1 iu/ml, sd = 452.1 iu/ml), which were higher than the normal value cited by the manufacturer (<100.0 iu/ml) in 32.1% of the samples. a significant difference was observed in csf samples from the p and c groups (p = 0.005) and in serum samples from the p group compared to the normal value (p = 0.005), with sera showing more frequent abnormal results.
Total IgE detection in paired cerebrospinal fluid and serum samples from patients with neurocysticercosis
BUENO Ednéia Casagranda,VAZ Adelaide José,MACHADO Luís dos Ramos,LIVRAMENTO José Antnio
Revista do Instituto de Medicina Tropical de S?o Paulo , 2000,
Abstract: Neurocysticercosis (NC), the presence of Taenia solium metacestodes in tissues, is the most frequent and severe parasitic infection of the central nervous system. We investigated the presence of total IgE by an automated chemiluminescence assay in 53 paired cerebrospinal fluid (CSF) and serum samples from patients with NC (P) and in 40 CSF samples from individuals with other neurological disorders as the control group (C). Total IgE concentration ranged from 1.2 to 6.6 IU/ml (mean = 1.4 IU/ml, standard deviation-sd = 1.1 IU/ml) in 28.3% of CSF samples from the P group, a value significantly higher than for the C group (£1.0 IU/ml). The serum samples from the P group showed concentrations ranging from 1.0 to 2330.0 IU/ml (mean = 224.1 IU/ml, sd = 452.1 IU/ml), which were higher than the normal value cited by the manufacturer (<100.0 IU/ml) in 32.1% of the samples. A significant difference was observed in CSF samples from the P and C groups (p = 0.005) and in serum samples from the P group compared to the normal value (p = 0.005), with sera showing more frequent abnormal results.
Applying science in practice: the optimization of biological therapy in rheumatoid arthritis
Sofia Ramiro, Pedro Machado, Jasvinder A Singh, Robert B Landewé, José António P da Silva
Arthritis Research & Therapy , 2010, DOI: 10.1186/ar3149
Abstract: The development of specific biological therapies has resulted in a remarkable improvement in the treatment of rheumatoid arthritis (RA) and also in the under-standing of its complex pathogenesis. We better recognize the multitude of cells and biological pathways involved in the disease process. We have also become more aware of the individual variability in disease features and in patterns of response to therapy. A large array of new treatment opportunities is currently under development and soon will be available as new biological agents. While enjoying these fruits of research, rheumatologists face the challenge of defining the best therapeutic plan for patients who have failed classical disease-modifying antirheumatic drugs (DMARDs).It is certainly desirable that our patients feel better and have improved function and acute-phase reactants as measured by response criteria, but the remaining inflammatory activity (status) seems decisive: 'It is good to feel better but it is better to feel good' [1]. Aletaha and colleagues [2] have demonstrated, in a pooled analysis based on data from several clinical trials in RA involving anti-tumor necrosis factor (anti-TNF), that within the ACR50 (American College of Rheumatology 50% improvement criteria) and ACR70 responder groups, the most important determinant of progression is the final disease state and not the relative degree of improvement. In fact, functional ability was best and radiographic progression was lowest in patients who had attained disease remission at 1 year compared with those who had attained only low or moderate disease activity. Further-more, among patients attaining the same disease activity category, physical function and radiographic progression did not differ significantly by the level of response. Even with low disease activity, damage progresses and only sustained remission is capable of abrogating progression of joint destruction [3]. Moreover, optimal disease control is associated with less work
Dynamics of Protein Phosphatase Gene Expression in Corbicula fluminea Exposed to Microcystin-LR and to Toxic Microcystis aeruginosa Cells
José Carlos Martins,Jo?o Machado,António Martins,Joana Azevedo,Luís OlivaTeles,Vitor Vasconcelos
International Journal of Molecular Sciences , 2011, DOI: 10.3390/ijms12129172
Abstract: This study investigated the in vivo effects of microcystins on gene expression of several phosphoprotein phosphatases (PPP) in the freshwater clam Corbicula fluminea with two different exposure scenarios. Clams were exposed for 96 h to 5 μg L ?1 of dissolved microcystin-LR and the relative changes of gene expression of three different types of PPP (PPP1, 2 and 4) were analyzed by quantitative real-time PCR. The results showed a significant induction of PPP2 gene expression in the visceral mass. In contrast, the cyanotoxin did not cause any significant changes on PPP1 and PPP4 gene expression. Based on these results, we studied alterations in transcriptional patterns in parallel with enzymatic activity of C. fluminea for PPP2, induced by a Microcystis aeruginosa toxic strain (1 × 10 5 cells cm ?3) during 96 h. The relative changes of gene expression and enzyme activity in visceral mass were analyzed by quantitative real-time PCR and colorimetric assays respectively. The clams exhibited a significant reduction of PPP2 activity with a concomitant enhancement of gene expression. Considering all the results we can conclude that the exposure to an ecologically relevant concentration of pure or intracellular microcystins (-LR) promoted an in vivo effect on PPP2 gene expression in C. fluminea.
Kinematic analysis and modelling of biped locomotion systems
Silva, Filipe Miguel Teixeira Pereira da;Machado, José Antnio Tenreiro;
Journal of the Brazilian Society of Mechanical Sciences , 1999, DOI: 10.1590/S0100-73861999000300003
Abstract: this paper presents the kinematic study of robotic biped locomotion systems. the main purpose is to determine the kinematic characteristics and the system performance during walking. for that objective, the prescribed motion of the biped is completely characterised in terms of five locomotion variables: step length, hip height, maximum hip ripple, maximum foot clearance and link lengths. in this work, we propose four methods to quantitatively measure the performance of the walking robot: energy analysis, perturbation analysis, lowpass frequency response and locomobility measure. these performance measures are discussed and compared in determining the robustness and effectiveness of the resulting locomotion.
Species diversity of sandflies (Diptera: Psychodidae) during different seasons and in different environments in the district of Taquaru?ú, state of Tocantins, Brazil
Machado, Tamara Oliveira;Bragan?a, Marcos Antnio Lima;Carvalho, Muzenilha Lima;Andrade Filho, José Dilermando;
Memórias do Instituto Oswaldo Cruz , 2012, DOI: 10.1590/S0074-02762012000700021
Abstract: phlebotomine sandflies are the vectors for the protozoan parasites that cause leishmaniasis. the present study investigated the species composition of sandfly fauna in the rural district of taquaru?ú, municipality of palmas, state of tocantins, brazil and compared the diversity of species among intradomicile, peridomicile and forest environments during the dry and rainy seasons. sandflies were collected using cdc light traps over the course of three months during the dry and rainy seasons. a total of 767 specimens were captured, belonging to different 32 species. the most abundant species were micropygomyia goiana (martins, falc?o & silva), sciopemyia sordellii (shannon & del ponte), evandromyia carmelinoi (ryan fraiha, lainson & shaw), evandromyia termitophila (martins, falc?o & silva), nyssomyia whitmani (antunes & coutinho) and lutzomyia longipalpis (lutz & neiva). the highest species diversity (30) and the greatest percentage of specimens (78.3%) were obtained during the rainy season. during the dry season, the species richness and abundance were greater in domestic environments. however, during the rainy season, the forest displayed the highest species richness and the domestic environment exhibited the greatest species abundance. several important vector species are reported in this study.
A computerized system to conduct the Tweed-Merrifield analysis in orthodontics
Barreto, Maximino Brand?o;Fonseca, Eduardo Machado;Cunha, Antnio José Ledo Alves da;
Brazilian Oral Research , 2006, DOI: 10.1590/S1806-83242006000200014
Abstract: precision in orthodontic diagnosis can increase the chance of therapeutic success. the objective of this study was to describe the development of a computerized system (prototype), created from a printed table of the cranial facial analysis and total dentition space analysis with difficulty index - tweed-merrifield analysis - in order to aid orthodontic diagnosis. the analysis was transposed from the manual format to the digital format. a user-logical and clear interface was sought for the development of the prototype, consisting of tables and graphs, including automatic, fast and accurate calculations. the result was the immediate visualization of the resolution of the analysis after filling out the fields on the computer. this technological innovation can be a helpful instrument for the orthodontist that favors a more accurate dental-cranial-facial analysis, increases patient safety, orients conduct and may contribute to teaching and research.
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