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Search Results: 1 - 10 of 74285 matches for " Johnny Y Jiang "
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Antihypertensive drug class and impaired fasting glucose: a risk association study among Chinese patients with uncomplicated hypertension
Martin CS Wong, Johnny Y Jiang, H Fung, Sian Griffiths, Stewart Mercer
BMC Pharmacology and Toxicology , 2008, DOI: 10.1186/1472-6904-8-6
Abstract: The odds ratios of having above borderline (≥ 6.1 mmol/l) and adverse (≥ 7.0 mmol/l) glucose levels, respectively, were studied according to patient age, gender, socioeconomic status, clinic types and antihypertensive drug classes by multivariable regression analyses.The fasting glucose levels were statistically similar (p = 0.786) among patients prescribed thiazide diuretics (5.48 mmol/l, 95%, 5.38, 5.59), calcium channel blockers (5.46 mmol/l, 95% C.I. 5.37, 5.54), β-blockers (5.42 mmol/l, 95% C.I. 5.34, 5.51) and drugs acting on the renin angiotensin system (RAS) [5.41 mmol/l, 95% C.I. 5.20, 5.61]. Multivariate analyses reported no significant associations between antihypertensive drug class and impaired fasting glucose. Elderly patients and male gender were significantly more likely to present with above borderline and adverse readings respectively.Clinicians should be aware of the increased risk of impaired fasting glucose in these groups, and use of thiazides should not in itself deter its use as a first-line antihypertensive agent among ethnic Chinese patients.Hypertension was estimated to be present in at least 73% of citizens in the United States who have diabetes [1]. Many people were diagnosed with hypertension prior to diabetes [2], and a significant number of hypertensive patients have diabetes gone unrecognized [3]. Diabetes was reported to impose a two-fold or greater risk for cardiovascular morbidity and mortality [4] and together with hypertension this risk increased dramatically [5]. The co-existence of diabetes and hypertension are associated with greater degrees of arterial stiffness [6] which leads to earlier rises in systolic and pulse pressures [7].The importance of early detection of diabetes among hypertensive patients has been highlighted in the guidelines of the American Diabetes Association [8] and the seventh report of the Joint National Committee [9], which called for screening for diabetes at the time of diagnosing hypertension and rep
Predictors of switching from beta-blockers to other anti-hypertensive drugs: a review of records of 19,177 Chinese patients seen in public primary care clinics in the New Territory East, Hong Kong
Martin CS Wong, Harry HX Wang, Johnny Y Jiang, Stephen Leeder, Sian M Griffiths
Asia Pacific Family Medicine , 2011, DOI: 10.1186/1447-056x-10-10
Abstract: We used a validated database which consisted of the demographic and clinical information of all Chinese patients prescribed a beta-blocker from any public, family practice clinics between 01 Jan 2004 to 30 June 2007 in one large Territory of Hong Kong. The proportion of patients switched from beta-blockers to another antihypertensive agent 180 days within their first prescription was studied, and the factors associated with medication switching were evaluated by using multivariate regression analyses.From 19,177 eligible subjects with a mean age of 59.1 years, 763 (4.0%) were switched from their beta-blockers within 180 days of commencing therapy. A binary logistic regression model used medication switching as the outcome variable and controlled for age, gender, socioeconomic status, clinic setting (general out-patient clinics, family medicine specialist clinic or staff clinics), district of residence, visit type (new vs. follow-up attendance), the number of concomitant co-morbidities, and the calendar year of prescription. It was found that older patients (age 50-59 years: adjusted odds ratio [AOR] 1.38, 95% C.I. 1.12-1.70; p = 0.002; age 60-69 years: AOR 1.63 95% C.I. 1.30-2.04, p < 0.001; age ≥ 70 years: AOR 1.82, 95% C.I. 1.46-2.26, p < 0.001; referent age < 50 years) and new visitors (AOR 0.57, 95% C.I. 0.48-0.68, p < 0.001) were more likely to have their medication switched.Closer monitoring of the medication taking behavior among the older patients and the new clinic visitors prescribed a beta-blocker is warranted. Future studies should evaluate the reasons of drug switching.Hypertension is a global health problem and represents one of the most important, modifiable risk factors for renal and cardiovascular diseases [1] It affects more than 30% of the general US population [2], and estimates of the cost of the disorder are around $66.4 billion worldwide in 2007 [3]. Its prevalence is high over the globe, including Asia Pacific countries [4]. Despite the effec
Health services research in the public healthcare system in Hong Kong: An analysis of over 1 million antihypertensive prescriptions between 2004–2007 as an example of the potential and pitfalls of using routinely collected electronic patient data
Martin CS Wong, Johnny Y Jiang, Jin-ling Tang, Augustine Lam, Hong Fung, Stewart W Mercer
BMC Health Services Research , 2008, DOI: 10.1186/1472-6963-8-138
Abstract: Data on antihypertensive drug prescriptions were retrieved from the electronic Clinical Management System (e-CMS) of all primary care clinics run by the Health Authority (HA) in the New Territory East (NTE) cluster of Hong Kong between January 2004 and June 2007. Information was also retrieved on patients' demographic and socioeconomic characteristics, visit type (new or follow-up), and relevant diseases (International Classification of Primary Care, ICPC codes).1,096,282 visit episodes were accessed, representing 93,450 patients. Patients' demographic and socio-economic details were recorded in all cases. Prescription details for anti-hypertensive drugs were missing in only 18 patients (0.02%). However, ICPC-code was missing for 36,409 patients (39%). Significant independent predictors of whether disease codes were applied included patient age ≥ 70 years (OR 2.18), female gender (OR 1.20), district of residence (range of ORs in more rural districts; 0.32–0.41), type of clinic (OR in Family Medicine Specialist Clinics; 1.45) and type of visit (OR follow-up visit; 2.39).In the 57,041 patients with an ICPC-code, uncomplicated hypertension (ICPC K86) was recorded in 45,859 patients (82.1%). The characteristics of these patients were very similar to those of the non-coded group, suggesting that most non-coded patients on antihypertensive drugs are likely to have uncomplicated hypertension.The e-CMS database of the HA in Hong Kong varies in quality in terms of recorded information. Potential future health services research using demographic and prescription information is highly feasible but for disease-specific research dependant on ICPC codes some caution is warranted. In the case of uncomplicated hypertension, future research on pharmaco-epidemiology (such as prescription patterns) and clinical issues (such as side-effects of medications on metabolic parameters) seems feasible given the large size of the data set and the comparability of coded and non-coded patients.T
The 3rd Asia Pacific Conference on EBM held on 26–28 November 2004, Hong Kong
Johnny Yu Jiang,Jin Ling Tang
Evidence-Based Complementary and Alternative Medicine , 2005, DOI: 10.1093/ecam/neh080
Abstract:
Generation of Non-Gaussian Wide-Sense Stationary Random Processes with Desired PSDs and PDFs  [PDF]
Milad Johnny
Journal of Signal and Information Processing (JSIP) , 2012, DOI: 10.4236/jsip.2012.34056
Abstract: This paper describes a new method to generate discrete signals with arbitrary power spectral density (PSD) and first order probability density function (PDF) without any limitation on PDFs and PSDs. The first approximation has been achieved by using a nonlinear transform function. At the second stage the desired PDF was approximated by a number of symmetric PDFs with defined variance. Each one provides a part of energy from total signal with different ratios of remained desired PSD. These symmetric PDFs defined by sinusoidal components with random amplitude, frequency and phase variables. Both analytic results and examples are included. The proposed scheme has been proved to be useful in simulations involving non-Gaussian processes with specific PSDs and PDFs.
Treatment of destillery wastewaters using coagulants and membranes
Rennola,Leonardo; Yépez,Carlos; Bullón,Johnny; Salazar,Franklin;
Revista Técnica de la Facultad de Ingeniería Universidad del Zulia , 2007,
Abstract: the present work studies the feasibility to treat distillery wastewaters (vinasses) using the coagulants: polyaluminum chloride, anionic and cationic polyacrylamide, a mixture of them and an ultrafiltration membrane. the vinasse was characterized carrying out color and turbidity measures. the optimal coagulant and its dose were determined. the reduction in turbidity was found to be 0%, 35% and 70% when anionic, cationic polyacrylamide and polyaluminum chloride respectively were used; when mixing pac with the cationic polyacrylamide, it was possible to obtain an additional 28% and 10% removal in turbidity and color respectively. afterwards, the vinasse was filtered using an ultrafiltration process with a ceramic membrane of 0.005μm of pore diameter with and without coagulants. the results show a color and turbidity reduction of 70% and 90% respectively. when using coagulants the removal increased to 97%. it may be concluded that the efficiency of the coagulants used is low although its use together with an ultrafiltration membrane leads to satisfactory results.
Tratamiento de las aguas residuales de una destilería mediante el uso de coagulantes y membranas Treatment of destillery wastewaters using coagulants and membranes
Leonardo Rennola,Carlos Yépez,Johnny Bullón,Franklin Salazar
Revista Técnica de la Facultad de Ingeniería Universidad del Zulia , 2007,
Abstract: El objetivo del presente trabajo es estudiar la factibilidad del tratamiento de las aguas residuales de una destilería (vinazas) utilizando los coagulantes: cloruro de polialuminio, poliacrilamida aniónica y catiónica, mezcla de ellos y una membrana de ultrafiltración. Se caracterizó la vinaza realizándole medidas de color y turbidez. Se determinó el coagulante óptimo y su dosis. Se encontró que las poliacrilamidas aniónicas, catiónicas y el cloruro de polialumnio remueven la turbidez en 0%, 35% y 70% respectivamente. Con la mezcla PAM/PAC, se podría lograr una remoción adicional de hasta un 28% en la turbidez y 10% en color. Posteriormente se sometió la vinaza a un proceso de ultrafiltración con una membrana cerámica con diámetro de poro de 0.005μm con y sin el uso de coagulantes. Los resultados muestran una reducción de color en 70% y turbidez en 90%. Al usar coagulantes la remoción de la turbidez aumentó a 97%. Se concluye que la eficiencia de los coagulantes utilizados es baja aunque su uso en conjunto con una membrana de ultrafiltración conduce a resultados más satisfactorios. The present work studies the feasibility to treat distillery wastewaters (vinasses) using the coagulants: polyaluminum chloride, anionic and cationic polyacrylamide, a mixture of them and an ultrafiltration membrane. The vinasse was characterized carrying out color and turbidity measures. The optimal coagulant and its dose were determined. The reduction in turbidity was found to be 0%, 35% and 70% when anionic, cationic polyacrylamide and polyaluminum chloride respectively were used; when mixing PAC with the cationic polyacrylamide, it was possible to obtain an additional 28% and 10% removal in turbidity and color respectively. Afterwards, the vinasse was filtered using an ultrafiltration process with a ceramic membrane of 0.005μm of pore diameter with and without coagulants. The results show a color and turbidity reduction of 70% and 90% respectively. When using coagulants the removal increased to 97%. It may be concluded that the efficiency of the coagulants used is low although its use together with an ultrafiltration membrane leads to satisfactory results.
Etiology and Diagnosis of Major Depression—A Novel Quantitative Approach  [PDF]
Johnny T. Ottesen
Open Journal of Endocrine and Metabolic Diseases (OJEMD) , 2013, DOI: 10.4236/ojemd.2013.32018
Abstract:

Background: Classical psychiatric opinions are relative uncertain and treatment results are not impressive when dealing with major depression. Depression is related to the endocrine system, but despite much effort a good quantitative measure for characterizing depression has not yet emerged. Methods: Based on ACTH and cortisol levels and using clustering analysis and mixture effect modeling we propose a novel and scientifically based quantitative index, denoted the O-index. The O-index combines a weighted and scaled deviation from normal values in both ACTH and cortisol. Results: Using ANOVA we compare the O-index with opinions reach by classical psychiatric diagnostic procedure (sensitivity 83%, specificity 59%, likelihood ratio positive 2.0, and likelihood ratio negative 0.29). The O-index nicely refines the etiology of depression: Combined with clinical data for 29 subjects earlier reported three categories emerge (p = 4.4 × 10-13): hypocortisolemic depressed, non-depressed, and hypercotisolemic depressed. The O-index also reveals why it has been difficult to obtain good markers earlier. It explains that healthy subjects may have an elevated (suppressed) level of cortisol or ACTH, however, the healthy system is able to deal with such elevated (suppressed) levels by compensating through suppressing (stimulating) the other component. In contrast the O-index shows that depressed subjects are incapable of making such compensation to a satisfactory degree. We illustrate how the O-index may be used for diagnostic procedure. Discussion: The methods are discussed and based on the available data material we propose that the O-index may be used to improve the diagnostic procedure and consequently the follow-up treatment.

Toric Intraocular Lens Malposition Corrected by Lens Repositioning to Manifest Refractive Cylinder Axis in Patient with Irregular Astigmatism Due to Corneal Scar  [PDF]
Riley Sanders, Johnny Gayton
Open Journal of Ophthalmology (OJOph) , 2015, DOI: 10.4236/ojoph.2015.52010
Abstract: A case is presented of a patient with an unexpected poor visual result and subsequent correction following cataract removal surgery via phacoemulsification and intraocular lens implantation using a toric intraocular lens implant (IOL). The initial operation resulted in an uncorrected vision of 20/100 (0.70 logMAR). Retrospective analysis of the patient’s corneal topography revealed irregular astigmatism secondary to remote trauma to the cornea. The cylinder axis on manifest refraction (MR) was significantly different from measured keratometry, so a second procedure was performed to align the cylinder axis of the IOL with the steep axis on MR. This repositioning procedure improved visual outcome to a final uncorrected vision of 20/25 (0.10 logMAR) and best corrected acuity of 20/20 (0.0 logMAR).
Convergence of the Unmanned Aerial Industry  [PDF]
Johnny Elie Chamata
Theoretical Economics Letters (TEL) , 2017, DOI: 10.4236/tel.2017.72015
Abstract: Industry convergencethe merger of previously unrelated industriesis a model that has had a strong influence on various industries and received substantial attention among practitioners over the past years. Despite this, industry convergence has received little attention in the field of unmanned aircraft. As the unmanned aircraft industry is still in the infancy stage, exploring the industrial status may contribute to the technology’s body of knowledge and may be useful for entrepreneurial decision making. Thus, this research paper investigates the degree to which the unmanned aerial vehicle sector represents an example of industry convergence and predicts the consequences built upon it. The investigation is based on the convergence theory and evidence from the unmanned aerial systems industry is provided to support theoretical foundations. Conclusions show that unmanned aerial technology is converged to an undefined extent and the author calls for further related empirical research.
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